Page last updated: 2024-10-25

cimetidine and Anxiety

cimetidine has been researched along with Anxiety in 5 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"Twenty-one patients with endoscopically proven active duodenal ulcers were studied in a double-blind randomized trial comparing doxepin hydrochloride (50 mg during the first week, and 100 mg thereafter, at bedtime) and cimetidine (1,200 mg/day in four divided doses)."9.05Doxepin and cimetidine in the treatment of duodenal ulcer: a double-blind comparative study. ( Shah, BK; Shrivastava, RK; Siegal, H, 1985)
"Twenty-one patients with endoscopically proven active duodenal ulcers were studied in a double-blind randomized trial comparing doxepin hydrochloride (50 mg during the first week, and 100 mg thereafter, at bedtime) and cimetidine (1,200 mg/day in four divided doses)."5.05Doxepin and cimetidine in the treatment of duodenal ulcer: a double-blind comparative study. ( Shah, BK; Shrivastava, RK; Siegal, H, 1985)
" We studied the clinical importance of this effect in 10 patients, who were receiving long-term treatment with diazepam for anxiety, tension, or difficulty in sleeping, in an eight-week double-blind controlled study during which the diazepam dosage remained constant."2.65Clinical importance of the interaction of diazepam and cimetidine. ( Abernethy, DR; Greenblatt, DJ; Harmatz, JS; Morse, DS; Shader, RI, 1984)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wu, DY1
Guo, M1
Gao, YS1
Kang, YH1
Guo, JC1
Jiang, XL1
Chen, F1
Liu, T1
Li, M1
Greenblatt, DJ1
Abernethy, DR1
Morse, DS1
Harmatz, JS1
Shader, RI1
Yuzurihara, M1
Ikarashi, Y1
Ishige, A1
Sasaki, H1
Kuribara, H1
Maruyama, Y1
Shrivastava, RK1
Shah, BK1
Siegal, H1

Trials

3 trials available for cimetidine and Anxiety

ArticleYear
Clinical effects of psychological intervention and drug therapy against peptic ulcer.
    Asian Pacific journal of tropical medicine, 2012, Volume: 5, Issue:10

    Topics: Adult; Anti-Ulcer Agents; Anxiety; China; Cimetidine; Cognitive Behavioral Therapy; Combined Modalit

2012
Clinical importance of the interaction of diazepam and cimetidine.
    The New England journal of medicine, 1984, Jun-21, Volume: 310, Issue:25

    Topics: Adult; Anxiety; Cimetidine; Clinical Trials as Topic; Diazepam; Double-Blind Method; Drug Interactio

1984
Doxepin and cimetidine in the treatment of duodenal ulcer: a double-blind comparative study.
    Clinical therapeutics, 1985, Volume: 7, Issue:2

    Topics: Adult; Aged; Anxiety; Cimetidine; Clinical Trials as Topic; Depression; Double-Blind Method; Doxepin

1985

Other Studies

2 other studies available for cimetidine and Anxiety

ArticleYear
Drugs for esophageal reflux.
    The Medical letter on drugs and therapeutics, 1980, Mar-21, Volume: 22, Issue:6

    Topics: Antacids; Anxiety; Cimetidine; Gastroesophageal Reflux; Humans; Parasympathomimetics; Tremor

1980
Effects of drugs acting as histamine releasers or histamine receptor blockers on an experimental anxiety model in mice.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 67, Issue:1

    Topics: Animals; Anxiety; Cimetidine; Disease Models, Animal; Histamine Antagonists; Histamine Release; Inje

2000