cimetidine has been researched along with Angiogenesis, Pathologic in 10 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the effects of cimetidine and omeprazole on angiogenesis in granulation tissue and on the healing of gastric ulcers induced by acetic acid in rats." | 7.68 | Effects of cimetidine and omeprazole on angiogenesis in granulation tissue of acetic acid-induced gastric ulcers in rats. ( Goto, H; Hase, S; Segawa, K; Tsuchida, T; Tsukamoto, Y, 1990) |
| " TL-118, a novel drug combination has been recently developed to inhibit tumor angiogenesis." | 5.40 | TL-118 and gemcitabine drug combination display therapeutic efficacy in a MYCN amplified orthotopic neuroblastoma murine model--evaluation by MRI. ( Abramovitch, R; Corchia, N; Dery, E; Fried, I; Gross, E; Komar-Stossel, C; Meir, K, 2014) |
| "We investigated the effect of sucralfate on angiogenesis in granulation tissue of gastric ulcers induced by acetic acid in rats using the carmine dye method." | 3.68 | Short report: effect of sucralfate on angiogenesis in granulation tissue of acetic acid-induced gastric ulcers in rats. ( Arisawa, T; Goto, H; Hase, S; Niwa, Y; Tsuchida, T; Tsukamoto, Y, 1993) |
| "We investigated the effects of cimetidine and omeprazole on angiogenesis in granulation tissue and on the healing of gastric ulcers induced by acetic acid in rats." | 3.68 | Effects of cimetidine and omeprazole on angiogenesis in granulation tissue of acetic acid-induced gastric ulcers in rats. ( Goto, H; Hase, S; Segawa, K; Tsuchida, T; Tsukamoto, Y, 1990) |
| "Its anticancer effect is also compared to that of the other H(2) receptor antagonists as well as outcomes of cimetidine in clinical studies in cancer patients." | 2.47 | Cimetidine: an anticancer drug? ( Bobek, V; Kacprzak, G; Kolostova, K; Kubecova, M; Pinterova, D, 2011) |
| " TL-118, a novel drug combination has been recently developed to inhibit tumor angiogenesis." | 1.40 | TL-118 and gemcitabine drug combination display therapeutic efficacy in a MYCN amplified orthotopic neuroblastoma murine model--evaluation by MRI. ( Abramovitch, R; Corchia, N; Dery, E; Fried, I; Gross, E; Komar-Stossel, C; Meir, K, 2014) |
| "We present a first description of a pancreatic cancer patient treated with standard chemotherapy and TL-118, an anti-angiogenic combination of 4 drugs that target non-overlapping aspects of the angiogenic process (Provided by Tiltan Pharma Ltd for compassionate use)." | 1.39 | TL-118-anti-angiogenic treatment in pancreatic cancer: a case report. ( Appelbaum, L; Breuer, S; Hubert, A; Maimon, O; Peretz, T, 2013) |
| "Cimetidine is known to suppress the growth of several tumors, including gastrointestinal cancer, in humans and animals." | 1.32 | Roxatidine- and cimetidine-induced angiogenesis inhibition suppresses growth of colon cancer implants in syngeneic mice. ( Izumi, K; Okabe, S; Tomita, K, 2003) |
| "The histamine-induced increase in the content of VEGF protein in the conditioned medium was inhibited by the cyclic AMP antagonist Rp-cAMP (IC(50) 6." | 1.31 | Enhancement by histamine of vascular endothelial growth factor production in granulation tissue via H(2) receptors. ( Ghosh, AK; Hirasawa, N; Ohuchi, K, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Breuer, S | 1 |
| Maimon, O | 1 |
| Appelbaum, L | 1 |
| Peretz, T | 1 |
| Hubert, A | 1 |
| Komar-Stossel, C | 1 |
| Gross, E | 1 |
| Dery, E | 1 |
| Corchia, N | 1 |
| Meir, K | 1 |
| Fried, I | 1 |
| Abramovitch, R | 1 |
| Borentain, P | 1 |
| Carmona, S | 1 |
| Mathieu, S | 1 |
| Jouve, E | 1 |
| El-Battari, A | 1 |
| Gérolami, R | 1 |
| Kubecova, M | 1 |
| Kolostova, K | 1 |
| Pinterova, D | 1 |
| Kacprzak, G | 1 |
| Bobek, V | 1 |
| Suga, M | 1 |
| Morita, R | 1 |
| Kaneko, K | 1 |
| Kyo, S | 1 |
| Tomita, K | 1 |
| Izumi, K | 1 |
| Okabe, S | 1 |
| Tsukamoto, Y | 2 |
| Tsuchida, T | 2 |
| Goto, H | 2 |
| Hase, S | 2 |
| Arisawa, T | 1 |
| Niwa, Y | 1 |
| Ghosh, AK | 1 |
| Hirasawa, N | 1 |
| Ohuchi, K | 1 |
| Segawa, K | 1 |
| Smaje, LH | 1 |
| Noor, NM | 1 |
| Clough, GF | 1 |
1 review available for cimetidine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Cimetidine: an anticancer drug?
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Adhesion; Cell Proliferation; Cimetidine; Clinical T | 2011 |
9 other studies available for cimetidine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
TL-118-anti-angiogenic treatment in pancreatic cancer: a case report.
Topics: Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Cyclophos | 2013 |
TL-118 and gemcitabine drug combination display therapeutic efficacy in a MYCN amplified orthotopic neuroblastoma murine model--evaluation by MRI.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Prolifera | 2014 |
Inhibition of E-selectin expression on the surface of endothelial cells inhibits hepatocellular carcinoma growth by preventing tumor angiogenesis.
Topics: Amiloride; Animals; Carcinoma, Hepatocellular; Cell Proliferation; Cimetidine; E-Selectin; Endotheli | 2016 |
[Impact of cimetidine on growth and metastasis of surgically transplanted Lewis lung cancer].
Topics: Animals; Carcinoma, Lewis Lung; Cimetidine; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasm | 2003 |
Roxatidine- and cimetidine-induced angiogenesis inhibition suppresses growth of colon cancer implants in syngeneic mice.
Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Cimetidine; Colonic Neoplasms; Male; Mice; Mice, | 2003 |
Short report: effect of sucralfate on angiogenesis in granulation tissue of acetic acid-induced gastric ulcers in rats.
Topics: Animals; Carmine; Cimetidine; Disease Models, Animal; Drug Therapy, Combination; Granulation Tissue; | 1993 |
Enhancement by histamine of vascular endothelial growth factor production in granulation tissue via H(2) receptors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cells, Cultured; Cimetidine; Cyclic A | 2001 |
Effects of cimetidine and omeprazole on angiogenesis in granulation tissue of acetic acid-induced gastric ulcers in rats.
Topics: Acetates; Acetic Acid; Animals; Cimetidine; Dose-Response Relationship, Drug; Granulation Tissue; Ma | 1990 |
Changing sensitivity to H1 and H2 receptor antagonists in the growing vasculature.
Topics: Animals; Blood Flow Velocity; Blood Vessels; Capillary Permeability; Cimetidine; Female; Histamine; | 1988 |