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cimetidine and Anemia, Hypoplastic

cimetidine has been researched along with Anemia, Hypoplastic in 14 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Research Excerpts

ExcerptRelevanceReference
"A 72-year-old woman had been given cimetidine 400mg/day for her gastritis since June 17, 1987."7.68[Cimetidine-induced aplastic anemia complicated with nonbacterial thrombotic endocarditis and cerebral infarction]. ( Itoh, T; Miyanishi, E; Morita, K; Nakase, K; Shirakawa, S; Tsuji, K, 1990)
"A 72-year-old woman had been given cimetidine 400mg/day for her gastritis since June 17, 1987."3.68[Cimetidine-induced aplastic anemia complicated with nonbacterial thrombotic endocarditis and cerebral infarction]. ( Itoh, T; Miyanishi, E; Morita, K; Nakase, K; Shirakawa, S; Tsuji, K, 1990)
" Aplastic anemia patients were used to establish a population pharmacokinetic model by the nonlinear mixed effect (NONMEM), and concentrations of ciclosporin were simulated by Monte Carlo method."1.72Effects of cimetidine on ciclosporin population pharmacokinetics and initial dose optimization in aplastic anemia patients. ( Chen, X; He, SM; Mao, YZ; Wang, DD; Yang, Y; Yin, D; Zheng, ZQ, 2022)
"The immune-mediated aplastic anemia mice model was induced by irradiation and half-matched allogeneic lymphocytes transfusion (ALT)."1.31[The development of immune-mediated aplastic anemia in mice can be blocked by cimetidine]. ( Jiang, Z; Liao, J; Lin, C; Ma, X; Wang, M; Zhao, X, 2000)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19909 (64.29)18.7374
1990's2 (14.29)18.2507
2000's2 (14.29)29.6817
2010's0 (0.00)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Wang, DD1
He, SM1
Yang, Y1
Mao, YZ1
Yin, D1
Zheng, ZQ1
Chen, X1
Wang, M2
Yang, L1
Guo, X1
Chen, S1
Liao, J2
Urban, C1
Zoubek, A1
Krottmayer, G1
Slavc, I1
Kaulfersch, W1
Wagner, K1
Farber, BF1
Brody, JP1
Tonkonow, B1
Hoffman, R1
Xia, T1
Wang, QR1
Xu, YH1
Zhao, X1
Lin, C1
Jiang, Z1
Ma, X1
Schapira, DV1
Bennett, JM1
Gouffier, E1
Schnurmann, D1
Durepaire, H1
Vernant, JB1
Nakase, K1
Itoh, T1
Tsuji, K1
Miyanishi, E1
Morita, K1
Shirakawa, S1
Dohlsten, M1
Hedlund, G1
Bekassy, AN1
Lindén, O1
Garwicz, S1
Wiebe, T1
Sjögren, HO1
Carlsson, R1
Miyawaki, S1
Nemoto, K1
Yashiro, K1
Takahashi, K1
Andoh, K1
Karasawa, M1
Omine, M1
Tsuchiya, J1
Maekawa, T1
Yao, E1
Tsukasaki, K1
Kamei, T1
Kuriyama, K1
Ichimaru, M1
Fujishita, M1
Uemura, Y1
Kotani, S1
Takehara, N1
Matsuoka, T1
Taguchi, H1
Miyoshi, I1
Okazaki, K1

Other Studies

14 other studies available for cimetidine and Anemia, Hypoplastic

ArticleYear
Effects of cimetidine on ciclosporin population pharmacokinetics and initial dose optimization in aplastic anemia patients.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2022, Jul-01, Volume: 174

    Topics: Anemia, Aplastic; Cimetidine; Cyclosporine; Humans; Immunosuppressive Agents; Metabolic Clearance Ra

2022
[The in vitro inhibitory effect of CD8+ cells from patients with aplastic anemia on normal CFU-GM growth was blocked by cimetidine].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 1997, Volume: 18, Issue:4

    Topics: Adult; Aged; Anemia, Aplastic; Case-Control Studies; CD8 Antigens; Cell Proliferation; Cimetidine; F

1997
[Immunosuppressive treatment of severe aplastic anemia with high-dose methylprednisolone and antithymocyte globulin in 2 patients].
    Wiener klinische Wochenschrift, 1984, Mar-16, Volume: 96, Issue:6

    Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Blood Transfusion; Cimetidine; Female; Humans; I

1984
Rapid development of aplastic anemia after intravenous chloramphenicol and cimetidine therapy.
    Southern medical journal, 1981, Volume: 74, Issue:10

    Topics: Anemia, Aplastic; Chloramphenicol; Cimetidine; Drug Interactions; Guanidines; Humans; Injections, In

1981
Aplastic anemia and cimetidine.
    Archives of internal medicine, 1980, Volume: 140, Issue:8

    Topics: Anemia, Aplastic; Bone Marrow Diseases; Cimetidine; Female; Guanidines; Humans; Middle Aged

1980
Cimetidine inhibits production of interferon gamma and tumor necrosis factor alpha by splenocytes in aplastic anemic mice.
    Acta pharmacologica Sinica, 2001, Volume: 22, Issue:3

    Topics: Anemia, Aplastic; Animals; Cells, Cultured; Cimetidine; Female; Histamine H2 Antagonists; Interferon

2001
[The development of immune-mediated aplastic anemia in mice can be blocked by cimetidine].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2000, Volume: 21, Issue:10

    Topics: Anemia, Aplastic; Animals; Bone Marrow; Cimetidine; Dose-Response Relationship, Drug; Female; Histam

2000
Cimetidine for pruritus.
    Lancet (London, England), 1979, Mar-31, Volume: 1, Issue:8118

    Topics: Aged; Anemia, Aplastic; Cimetidine; Female; Guanidines; Humans; Pruritus

1979
[Transient marrow aplasia during cimetidine treatment].
    La Nouvelle presse medicale, 1978, Sep-16, Volume: 7, Issue:30

    Topics: Aged; Anemia, Aplastic; Cimetidine; Guanidines; Humans; Leukopenia; Male

1978
[Cimetidine-induced aplastic anemia complicated with nonbacterial thrombotic endocarditis and cerebral infarction].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1990, Volume: 31, Issue:12

    Topics: Aged; Anemia, Aplastic; Cerebral Infarction; Cimetidine; Endocarditis; Female; Gastritis; Humans; Pa

1990
Lymphocyte subpopulations and lymphokine production in children with constitutional aplastic anemia.
    Pediatric hematology and oncology, 1988, Volume: 5, Issue:2

    Topics: Anemia, Aplastic; Antigens, Differentiation; Child; Child, Preschool; Cimetidine; Cyclosporins; Fema

1988
[Cimetidine-induced aplastic anemia: a case report].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:4

    Topics: Aged; Aged, 80 and over; Anemia, Aplastic; Cimetidine; Humans; Male

1988
[Effect of bolus methylprednisolone therapy on a case of cimetidine-associated aplastic anemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1987, Volume: 28, Issue:1

    Topics: Aged; Anemia, Aplastic; Cimetidine; Duodenal Ulcer; Humans; Male; Methylprednisolone

1987
[Cimetidine-induced hypoplastic anemia complicated by hepatoma: report of a case].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1985, Volume: 26, Issue:8

    Topics: Anemia, Aplastic; Cimetidine; Embolization, Therapeutic; Hematoma; Humans; Liver Neoplasms; Male; Mi

1985