cimetidine has been researched along with Anemia, Aplastic in 14 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Anemia, Aplastic: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 72-year-old woman had been given cimetidine 400mg/day for her gastritis since June 17, 1987." | 7.68 | [Cimetidine-induced aplastic anemia complicated with nonbacterial thrombotic endocarditis and cerebral infarction]. ( Itoh, T; Miyanishi, E; Morita, K; Nakase, K; Shirakawa, S; Tsuji, K, 1990) |
| "A 72-year-old woman had been given cimetidine 400mg/day for her gastritis since June 17, 1987." | 3.68 | [Cimetidine-induced aplastic anemia complicated with nonbacterial thrombotic endocarditis and cerebral infarction]. ( Itoh, T; Miyanishi, E; Morita, K; Nakase, K; Shirakawa, S; Tsuji, K, 1990) |
| " Aplastic anemia patients were used to establish a population pharmacokinetic model by the nonlinear mixed effect (NONMEM), and concentrations of ciclosporin were simulated by Monte Carlo method." | 1.72 | Effects of cimetidine on ciclosporin population pharmacokinetics and initial dose optimization in aplastic anemia patients. ( Chen, X; He, SM; Mao, YZ; Wang, DD; Yang, Y; Yin, D; Zheng, ZQ, 2022) |
| "The immune-mediated aplastic anemia mice model was induced by irradiation and half-matched allogeneic lymphocytes transfusion (ALT)." | 1.31 | [The development of immune-mediated aplastic anemia in mice can be blocked by cimetidine]. ( Jiang, Z; Liao, J; Lin, C; Ma, X; Wang, M; Zhao, X, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (64.29) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, DD | 1 |
| He, SM | 1 |
| Yang, Y | 1 |
| Mao, YZ | 1 |
| Yin, D | 1 |
| Zheng, ZQ | 1 |
| Chen, X | 1 |
| Wang, M | 2 |
| Yang, L | 1 |
| Guo, X | 1 |
| Chen, S | 1 |
| Liao, J | 2 |
| Urban, C | 1 |
| Zoubek, A | 1 |
| Krottmayer, G | 1 |
| Slavc, I | 1 |
| Kaulfersch, W | 1 |
| Wagner, K | 1 |
| Farber, BF | 1 |
| Brody, JP | 1 |
| Tonkonow, B | 1 |
| Hoffman, R | 1 |
| Xia, T | 1 |
| Wang, QR | 1 |
| Xu, YH | 1 |
| Zhao, X | 1 |
| Lin, C | 1 |
| Jiang, Z | 1 |
| Ma, X | 1 |
| Schapira, DV | 1 |
| Bennett, JM | 1 |
| Gouffier, E | 1 |
| Schnurmann, D | 1 |
| Durepaire, H | 1 |
| Vernant, JB | 1 |
| Nakase, K | 1 |
| Itoh, T | 1 |
| Tsuji, K | 1 |
| Miyanishi, E | 1 |
| Morita, K | 1 |
| Shirakawa, S | 1 |
| Dohlsten, M | 1 |
| Hedlund, G | 1 |
| Bekassy, AN | 1 |
| Lindén, O | 1 |
| Garwicz, S | 1 |
| Wiebe, T | 1 |
| Sjögren, HO | 1 |
| Carlsson, R | 1 |
| Miyawaki, S | 1 |
| Nemoto, K | 1 |
| Yashiro, K | 1 |
| Takahashi, K | 1 |
| Andoh, K | 1 |
| Karasawa, M | 1 |
| Omine, M | 1 |
| Tsuchiya, J | 1 |
| Maekawa, T | 1 |
| Yao, E | 1 |
| Tsukasaki, K | 1 |
| Kamei, T | 1 |
| Kuriyama, K | 1 |
| Ichimaru, M | 1 |
| Fujishita, M | 1 |
| Uemura, Y | 1 |
| Kotani, S | 1 |
| Takehara, N | 1 |
| Matsuoka, T | 1 |
| Taguchi, H | 1 |
| Miyoshi, I | 1 |
| Okazaki, K | 1 |
14 other studies available for cimetidine and Anemia, Aplastic
| Article | Year |
|---|---|
Effects of cimetidine on ciclosporin population pharmacokinetics and initial dose optimization in aplastic anemia patients.
Topics: Anemia, Aplastic; Cimetidine; Cyclosporine; Humans; Immunosuppressive Agents; Metabolic Clearance Ra | 2022 |
[The in vitro inhibitory effect of CD8+ cells from patients with aplastic anemia on normal CFU-GM growth was blocked by cimetidine].
Topics: Adult; Aged; Anemia, Aplastic; Case-Control Studies; CD8 Antigens; Cell Proliferation; Cimetidine; F | 1997 |
[Immunosuppressive treatment of severe aplastic anemia with high-dose methylprednisolone and antithymocyte globulin in 2 patients].
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Blood Transfusion; Cimetidine; Female; Humans; I | 1984 |
Rapid development of aplastic anemia after intravenous chloramphenicol and cimetidine therapy.
Topics: Anemia, Aplastic; Chloramphenicol; Cimetidine; Drug Interactions; Guanidines; Humans; Injections, In | 1981 |
Aplastic anemia and cimetidine.
Topics: Anemia, Aplastic; Bone Marrow Diseases; Cimetidine; Female; Guanidines; Humans; Middle Aged | 1980 |
Cimetidine inhibits production of interferon gamma and tumor necrosis factor alpha by splenocytes in aplastic anemic mice.
Topics: Anemia, Aplastic; Animals; Cells, Cultured; Cimetidine; Female; Histamine H2 Antagonists; Interferon | 2001 |
[The development of immune-mediated aplastic anemia in mice can be blocked by cimetidine].
Topics: Anemia, Aplastic; Animals; Bone Marrow; Cimetidine; Dose-Response Relationship, Drug; Female; Histam | 2000 |
Cimetidine for pruritus.
Topics: Aged; Anemia, Aplastic; Cimetidine; Female; Guanidines; Humans; Pruritus | 1979 |
[Transient marrow aplasia during cimetidine treatment].
Topics: Aged; Anemia, Aplastic; Cimetidine; Guanidines; Humans; Leukopenia; Male | 1978 |
[Cimetidine-induced aplastic anemia complicated with nonbacterial thrombotic endocarditis and cerebral infarction].
Topics: Aged; Anemia, Aplastic; Cerebral Infarction; Cimetidine; Endocarditis; Female; Gastritis; Humans; Pa | 1990 |
Lymphocyte subpopulations and lymphokine production in children with constitutional aplastic anemia.
Topics: Anemia, Aplastic; Antigens, Differentiation; Child; Child, Preschool; Cimetidine; Cyclosporins; Fema | 1988 |
[Cimetidine-induced aplastic anemia: a case report].
Topics: Aged; Aged, 80 and over; Anemia, Aplastic; Cimetidine; Humans; Male | 1988 |
[Effect of bolus methylprednisolone therapy on a case of cimetidine-associated aplastic anemia].
Topics: Aged; Anemia, Aplastic; Cimetidine; Duodenal Ulcer; Humans; Male; Methylprednisolone | 1987 |
[Cimetidine-induced hypoplastic anemia complicated by hepatoma: report of a case].
Topics: Anemia, Aplastic; Cimetidine; Embolization, Therapeutic; Hematoma; Humans; Liver Neoplasms; Male; Mi | 1985 |