Page last updated: 2024-10-25

cimetidine and Anaphylactic Reaction

cimetidine has been researched along with Anaphylactic Reaction in 57 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Research Excerpts

ExcerptRelevanceReference
"Combination therapy blocking both PAF and histamine markedly reduces the severity of peanut-induced anaphylaxis, and thus it may be a potential life-saving therapeutic approach in peanut and, likely, other food-induced anaphylaxis."7.75Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions. ( Arias, K; Baig, M; Chu, D; Colangelo, M; Coyle, A; Goncharova, S; Jordana, M; Vadas, P; Walker, T; Waserman, S, 2009)
"To elucidate the role of histamine in each of these symptoms, we induced the passive systemic anaphylaxis reaction in histidine decarboxylase gene knockout (HDC [-/-]) mice, which lack histamine."7.71The control effect of histamine on body temperature and respiratory function in IgE-dependent systemic anaphylaxis. ( Adachi, T; Hori, Y; Ishigaki-Suzuki, S; Kagaya, Y; Kikuchi, Y; Makabe-Kobayashi, Y; Nagy, A; Ohtsu, H; Shirato, K; Takai, T; Ujike, A; Watanabe, T, 2002)
" This study describes the effects of histamine and platelet-activating factor (PAF) antagonism (combined) on IgE-induced systemic anaphylaxis in the rabbit."7.68The effects of combined histamine and platelet-activating factor antagonism on systemic anaphylaxis induced by immunoglobulin E in the rabbit. ( Halonen, M; Lohman, IC, 1993)
"The respiratory and circulatory alterations induced by intravenous histamine in the pentobarbital anesthetized rabbit were examined and compared to those alterations associated with IgE anaphylaxis following antigen challenge."7.67The role of histamine in the physiologic alterations of IgE anaphylaxis in the rabbit. ( Halonen, M; Lohman, IC; Palmer, JD, 1984)
"Cardiac anaphylaxis was elicited in isolated working guinea pig hearts in the presence of the histamine receptor antagonists pyrilamine and cimetidine, adenosine or hydrocortisone."7.67Protective effects of histamine H1 and H2 antagonists, adenosine and hydrocortisone on cardiac anaphylaxis. ( Guo, ZG; Qiu, R, 1989)
"Intravenous cimetidine treatment was prescribed for patients suffering from anaphylaxis, urticaria, pruritus, and contact dermatitis."7.67Intravenous cimetidine as an effective treatment for systemic anaphylaxis and acute allergic skin reactions. ( Asano, M; Au-Yong, TF; Kimura, S; Mayumi, H; Shimokawa, T; Yayama, T, 1987)
" After immunization with ovalbumin (OVA), a common dietary constituent, we evaluated the efficacy of pretreatment with histamine-receptor or serotonin-receptor blockers administered alone or in combination with a nitric oxide synthase inhibitor (L-NAME) on OVA-induced anaphylactic shock in Brown Norway rats."5.32Constitutive nitric oxide synthase inhibition combined with histamine and serotonin receptor blockade improves the initial ovalbumin-induced arterial hypotension but decreases the survival time in brown norway rats anaphylactic shock. ( Bellou, A; Gerard, P; Gillois, P; Guéant, JL; Lambert, H; Longrois, D; Mallié, JP; Montémont, C; Sainte-Laudy, J; Vauthier, E, 2003)
"Of the 35 patients with pruritus, all 12 receiving diphenhydramine placebo had clinically significant relief compared with six of ten (60%) receiving cimetidine plus placebo (P = ."5.07Histamine antagonists in the treatment of acute allergic reactions. ( Caravati, EM; Hartsell, SC; Martinez, JC; Runge, JW; Williamson, SG, 1992)
"Combination therapy blocking both PAF and histamine markedly reduces the severity of peanut-induced anaphylaxis, and thus it may be a potential life-saving therapeutic approach in peanut and, likely, other food-induced anaphylaxis."3.75Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions. ( Arias, K; Baig, M; Chu, D; Colangelo, M; Coyle, A; Goncharova, S; Jordana, M; Vadas, P; Walker, T; Waserman, S, 2009)
"To elucidate the role of histamine in each of these symptoms, we induced the passive systemic anaphylaxis reaction in histidine decarboxylase gene knockout (HDC [-/-]) mice, which lack histamine."3.71The control effect of histamine on body temperature and respiratory function in IgE-dependent systemic anaphylaxis. ( Adachi, T; Hori, Y; Ishigaki-Suzuki, S; Kagaya, Y; Kikuchi, Y; Makabe-Kobayashi, Y; Nagy, A; Ohtsu, H; Shirato, K; Takai, T; Ujike, A; Watanabe, T, 2002)
"We have investigated the antigen-stimulated release of calcitonin gene-related peptide (CGRP) from ovalbumin-sensitized guinea-pig isolated hearts and the interaction with other mediators of anaphylaxis released concomitantly."3.69Release of calcitonin gene-related peptide in cardiac anaphylaxis. ( Amann, R; Donnerer, J; Peskar, BA; Schuligoi, R, 1997)
" This study describes the effects of histamine and platelet-activating factor (PAF) antagonism (combined) on IgE-induced systemic anaphylaxis in the rabbit."3.68The effects of combined histamine and platelet-activating factor antagonism on systemic anaphylaxis induced by immunoglobulin E in the rabbit. ( Halonen, M; Lohman, IC, 1993)
" The edematogenic reaction appeared 5 min after the intraplantar injection of ovalbumin, peaked at 30 min after the antigenic challenge, and decreased thereafter."3.68Effect of PAF-acether antagonists on active anaphylactic mouse paw edema. ( Amorim, CZ; Cordeiro, RS; Henriques, MG; Vargaftig, BB; Weg, VB, 1991)
"The respiratory and circulatory alterations induced by intravenous histamine in the pentobarbital anesthetized rabbit were examined and compared to those alterations associated with IgE anaphylaxis following antigen challenge."3.67The role of histamine in the physiologic alterations of IgE anaphylaxis in the rabbit. ( Halonen, M; Lohman, IC; Palmer, JD, 1984)
"Cardiac anaphylaxis was elicited in isolated working guinea pig hearts in the presence of the histamine receptor antagonists pyrilamine and cimetidine, adenosine or hydrocortisone."3.67Protective effects of histamine H1 and H2 antagonists, adenosine and hydrocortisone on cardiac anaphylaxis. ( Guo, ZG; Qiu, R, 1989)
"Intravenous cimetidine treatment was prescribed for patients suffering from anaphylaxis, urticaria, pruritus, and contact dermatitis."3.67Intravenous cimetidine as an effective treatment for systemic anaphylaxis and acute allergic skin reactions. ( Asano, M; Au-Yong, TF; Kimura, S; Mayumi, H; Shimokawa, T; Yayama, T, 1987)
" Cimetidine decreased the tachycardia occurring during anaphylaxis but no effect on the inhibition of stimulation-induced transmitter release."3.66Are the prejunctional histamine receptors on sympathetic nerve terminals in guinea-pig isolated atria activated during anaphylaxis in vitro? ( Rand, MJ; Story, DF; Wong-Dusting, H, 1982)
"To evaluate the ability of histamine to induce ventricular arrhythmias, we studied the effects of histamine on ventricular rhythmicity in the isolated guinea pig heart with complete atrioventricular conduction block."3.66Acceleration of idioventricular rhythms by histamine in guinea pig heart: mediation by H2 receptors. ( Levi, R; Zavecz, JH, 1979)
" In a separate group of ten patients whose previous reactions to RCM were life threatening (shock), pretreatment was accompanied by a provocative dosing regimen."2.67Comparison of three pretreatment protocols to prevent anaphylactoid reactions to radiocontrast media. ( Lieberman, PL; Marshall, GD, 1991)
"Cutaneous anaphylactoid reactions following infusion of polygeline (Haemaccel) in orthopedic patients were successfully abolished by premedication with 0."2.65Prophylaxis of anaphylactoid reactions to a polypeptidal plasma substitute by H1- plus H2-receptor antagonists: synopsis of three randomized controlled trials. ( Doenicke, A; Lorenz, W; Schöning, B, 1982)
" After immunization with ovalbumin (OVA), a common dietary constituent, we evaluated the efficacy of pretreatment with histamine-receptor or serotonin-receptor blockers administered alone or in combination with a nitric oxide synthase inhibitor (L-NAME) on OVA-induced anaphylactic shock in Brown Norway rats."1.32Constitutive nitric oxide synthase inhibition combined with histamine and serotonin receptor blockade improves the initial ovalbumin-induced arterial hypotension but decreases the survival time in brown norway rats anaphylactic shock. ( Bellou, A; Gerard, P; Gillois, P; Guéant, JL; Lambert, H; Longrois, D; Mallié, JP; Montémont, C; Sainte-Laudy, J; Vauthier, E, 2003)
"Treatment with dimaprit at 6 and 60 microM for 20 min significantly inhibited the anaphylactic histamine release, whereas betahistine at up to 80 microM under the same conditions did not affect it."1.29Dimaprit, a histamine H2-agonist, inhibits anaphylactic histamine release from mast cells and the decreased release is restored by thioperamide (H3-antagonist), but not by cimetidine (H2-antagonist). ( Kohno, S; Nabe, T; Ogawa, K; Ohata, K; Yamamura, H, 1993)
"Previous studies have shown that an anaphylactic reaction in the isolated perfused heart is characterized by drastic coronary constriction, arrhythmias, and severe impairment of contractility."1.28Characterization of cardiovascular events mediated by platelet activating factor during systemic anaphylaxis. ( Ahmad, Z; Baumann, G; Berdel, WE; Felix, SB; Hashemi, T; Niemczyk, M, 1990)
"Two case reports are described of acute anaphylactoid reactions following the administration of protamine to reverse the anticoagulation effect of heparin in patients undergoing coronary artery bypass graft surgery."1.28Histamine 2 receptor blocker in the treatment of protamine related anaphylactoid reactions: two case reports. ( Kambam, JR; Merrill, WH; Smith, BE, 1989)
"Treatment with cimetidine (1 mg kg-1) or dimaprit (1 mg kg-1) did not influence the response capacity to antigen challenge in IgG1- type animals."1.27Changes in bronchial anaphylactic reactivity induced in guinea-pigs by long-term treatment with histamine H2-agents. ( Andersson, P; Bergstrand, H, 1984)
"The danger of the anaphylactoid reactions which occur during pediatric general anesthesia leads the authors to use a specific antihistaminic premedication."1.27A specific antihistaminic premedication anti H1 anti H2 for pediatric anesthesia. ( Cupa, M; Fournier, JL; Khenifer, L; Le Mapihan, Y; Pierrot, M, 1984)
"There was no evidence of causes for the anaphylactic reactions over a two and a half year period."1.27Life-threatening idiopathic anaphylaxis associated with hyperimmunoglobulinemia E. ( Greenberger, PA, 1984)
"We have found that the anaphylactic reaction of these cardiac preparations is characterized by complement activation and C3a generation, as well as by histamine release and positive inotropic and chronotropic effects."1.27Activation of the third complement component (C3) and C3a generation in cardiac anaphylaxis: histamine release and associated inotropic and chronotropic effects. ( del Balzo, U; Levi, R; Polley, MJ, 1988)
"In this group there was not a single anaphylactic reaction."1.27Repeat chemonucleolysis. ( Sutton, JC, 1986)

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-199036 (63.16)18.7374
1990's12 (21.05)18.2507
2000's8 (14.04)29.6817
2010's1 (1.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duplancic, B1
Stambolija, V1
Holjevac, J1
Zemba, M1
Balenovic, I1
Drmic, D1
Suran, J1
Radic, B1
Filipovic, M1
Blagaic, AB1
Brcic, L1
Kolenc, D1
Grabarevic, Z1
Seiwerth, S1
Sikiric, P1
Arias, K1
Baig, M1
Colangelo, M1
Chu, D1
Walker, T1
Goncharova, S1
Coyle, A1
Vadas, P1
Waserman, S1
Jordana, M1
Makabe-Kobayashi, Y1
Hori, Y1
Adachi, T1
Ishigaki-Suzuki, S1
Kikuchi, Y1
Kagaya, Y1
Shirato, K1
Nagy, A1
Ujike, A1
Takai, T1
Watanabe, T1
Ohtsu, H1
Bellou, A1
Lambert, H1
Gillois, P1
Montémont, C1
Gerard, P1
Vauthier, E1
Sainte-Laudy, J1
Longrois, D1
Guéant, JL1
Mallié, JP1
Herzinger, T1
Behr, J1
Przybilla, B1
Hannaway, PJ1
Wong-Dusting, H1
Story, DF1
Rand, MJ1
Braibant, F1
Mélon, J1
Lecomte, J1
Damas, J1
Szczepaniak, K1
Kazimierczak, W1
Berstad, J1
Andersson, P1
Bergstrand, H1
Chand, N1
DeRoth, L1
Tryba, M1
Zevounou, F1
Zenz, M1
Le Mapihan, Y1
Pierrot, M1
Khenifer, L1
Fournier, JL1
Cupa, M1
Greenberger, PA2
Halonen, M2
Lohman, IC2
Palmer, JD1
Schöning, B2
Lorenz, W3
Doenicke, A3
Paré, P1
Miller, D1
Sandhu, BS1
Requena, R1
Knapp, AB1
Grimshaw, RS1
Goldfarb, JP1
Farkas, PS1
Rubin, M1
Rosenstreich, DL1
Baumann, G2
Loher, U1
Felix, SB2
Heidecke, CD1
Riess, G1
Ludwig, L1
Blömer, H1
Kohno, S2
Nakao, S1
Ogawa, K2
Yamamura, H2
Nabe, T2
Ohata, K2
Schuligoi, R1
Amann, R1
Donnerer, J1
Peskar, BA1
Robertson, PS1
Rhoney, DH1
Lynch, JP1
Renz, CL1
Laroche, D1
Moss, J1
Spengler, U1
Guo, Y1
Hedqvist, P1
Gustafsson, LE1
Dittmann, I1
Hug, P1
Schwarz, B1
Hutchcroft, BJ1
Moore, EG1
Orange, RP1
Levi, R2
Zavecz, JH1
Drazen, JM1
Venugopalan, CS1
Soter, NA1
Roberts, M1
Fisher, M1
Runge, JW1
Martinez, JC1
Caravati, EM1
Williamson, SG1
Hartsell, SC1
Atkinson, TP1
Kaliner, MA1
Amorim, CZ1
Henriques, MG1
Weg, VB1
Cordeiro, RS1
Vargaftig, BB1
Hashemi, T1
Niemczyk, M1
Ahmad, Z1
Berdel, WE1
Marshall, GD1
Lieberman, PL1
Kelly, JS1
Prielipp, RC1
Assem, ES1
Abdullah, NA1
Silverman, HJ1
Taylor, WR1
Smith, PL1
Kagey-Sobotka, A1
Permutt, S1
Lichtenstein, LM1
Bleecker, ER1
del Balzo, U1
Polley, MJ1
Kambam, JR2
Merrill, WH1
Smith, BE1
De Soto, H1
Turk, P1
Yarbrough, JA1
Moffitt, JE1
Brown, DA1
Stafford, CT1
Qiu, R2
Guo, ZG2
Ring, J1
Rothenberger, KH1
Clauss, W1
Patterson, R1
Tapio, CM1
Reimann, HJ1
Tauber, R1
Kramann, B1
Gmeinwieser, J1
Schmidt, U1
Reiser, M1
Sutton, JC1
Blandina, P1
Brunelleschi, S1
Fantozzi, R1
Giannella, E1
Mannaioni, PF1
Masini, E1
Dymond, R1
Krestow, M1
Handte, RE1
Mayumi, H1
Kimura, S1
Asano, M1
Shimokawa, T1
Au-Yong, TF1
Yayama, T1
Tanz, RD1
Kettelkamp, N1
Hirshman, CA1

Reviews

3 reviews available for cimetidine and Anaphylactic Reaction

ArticleYear
[Anaphylaxis due to contrast media].
    Der Internist, 2000, Volume: 41, Issue:8

    Topics: Anaphylaxis; Cimetidine; Contrast Media; Drug Interactions; Drug Therapy, Combination; Glucocorticoi

2000
Anaphylaxis.
    The Medical clinics of North America, 1992, Volume: 76, Issue:4

    Topics: Anaphylaxis; Cardiopulmonary Resuscitation; Cimetidine; Clinical Protocols; Complement Activation; D

1992
[Histamine H1 and H2 receptor blockade as a supplementary premedication principle in elective surgery].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1985, Mar-26, Volume: 74, Issue:13

    Topics: Adult; Anaphylaxis; Cimetidine; Clinical Trials as Topic; Dimethindene; Drug Eruptions; Histamine H1

1985

Trials

7 trials available for cimetidine and Anaphylactic Reaction

ArticleYear
[Prevention of anaphylactoid reactions using intramuscular promethazine and cimetidine. Studies of a histamine infusion model].
    Der Anaesthesist, 1984, Volume: 33, Issue:5

    Topics: Adult; Anaphylaxis; Blood Pressure; Cimetidine; Drug Therapy, Combination; Hemodynamics; Histamine;

1984
Prophylaxis of anaphylactoid reactions to a polypeptidal plasma substitute by H1- plus H2-receptor antagonists: synopsis of three randomized controlled trials.
    Klinische Wochenschrift, 1982, Sep-01, Volume: 60, Issue:17

    Topics: Adult; Anaphylaxis; Animals; Cimetidine; Clinical Trials as Topic; Dimethindene; Dogs; Female; Hista

1982
[Anaphylactoid reactions following administration of plasma substitutes in man. Prevention of this side-effect of haemaccel by premedication with H1- and H2-receptor antagonists (author's transl)].
    Der Anaesthesist, 1977, Volume: 26, Issue:12

    Topics: Anaphylaxis; Cimetidine; Dimethindene; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; M

1977
Histamine antagonists in the treatment of acute allergic reactions.
    Annals of emergency medicine, 1992, Volume: 21, Issue:3

    Topics: Adult; Anaphylaxis; Blood Pressure; Cimetidine; Diphenhydramine; Double-Blind Method; Drug Therapy,

1992
Comparison of three pretreatment protocols to prevent anaphylactoid reactions to radiocontrast media.
    Annals of allergy, 1991, Volume: 67, Issue:1

    Topics: Administration, Oral; Adult; Aged; Anaphylaxis; Cimetidine; Contrast Media; Diphenhydramine; Dose-Re

1991
[Histamine H1 and H2 receptor blockade as a supplementary premedication principle in elective surgery].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1985, Mar-26, Volume: 74, Issue:13

    Topics: Adult; Anaphylaxis; Cimetidine; Clinical Trials as Topic; Dimethindene; Drug Eruptions; Histamine H1

1985
Prevention of anaphylactoid reactions after radiographic contrast media infusion by combined histamine H1- and H2-receptor antagonists: results of a prospective controlled trial.
    International archives of allergy and applied immunology, 1985, Volume: 78, Issue:1

    Topics: Adolescent; Adult; Aged; Anaphylaxis; Cimetidine; Clemastine; Clinical Trials as Topic; Contrast Med

1985

Other Studies

48 other studies available for cimetidine and Anaphylactic Reaction

ArticleYear
Pentadecapeptide BPC 157 and anaphylactoid reaction in rats and mice after intravenous dextran and white egg administration.
    European journal of pharmacology, 2014, Mar-15, Volume: 727

    Topics: Administration, Intravenous; Anaphylaxis; Animals; Anti-Allergic Agents; Cimetidine; Dextrans; Disea

2014
Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions.
    The Journal of allergy and clinical immunology, 2009, Volume: 124, Issue:2

    Topics: Allergens; Anaphylaxis; Animals; Arachis; Cholera Toxin; Cimetidine; Disease Models, Animal; Drug Th

2009
The control effect of histamine on body temperature and respiratory function in IgE-dependent systemic anaphylaxis.
    The Journal of allergy and clinical immunology, 2002, Volume: 110, Issue:2

    Topics: Allergens; Anaphylaxis; Animals; Blood Pressure; Body Temperature; Cimetidine; Histamine; Histamine

2002
Constitutive nitric oxide synthase inhibition combined with histamine and serotonin receptor blockade improves the initial ovalbumin-induced arterial hypotension but decreases the survival time in brown norway rats anaphylactic shock.
    Shock (Augusta, Ga.), 2003, Volume: 19, Issue:1

    Topics: Anaphylaxis; Animals; Arteries; Cimetidine; Dihydroergotamine; Dinoprostone; Eicosanoids; Enzyme Inh

2003
[Tolerance induction in anaphylaxis to carboplatin].
    Deutsche medizinische Wochenschrift (1946), 2003, Jul-25, Volume: 128, Issue:30

    Topics: Abdominal Neoplasms; Aged; Anaphylaxis; Antineoplastic Agents; Carboplatin; Chemotherapy, Adjuvant;

2003
Emergency department treatment of anaphylaxis: is epinephrine always indicated?
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:1

    Topics: Aged; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Contraindications; Diphenhyd

2006
Are the prejunctional histamine receptors on sympathetic nerve terminals in guinea-pig isolated atria activated during anaphylaxis in vitro?
    The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:10

    Topics: Anaphylaxis; Animals; Cimetidine; Female; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Male;

1982
[Histamine receptors and clinical expression of some anaphylactic reactions].
    Revue medicale de Liege, 1984, Jun-01, Volume: 39, Issue:11

    Topics: Anaphylaxis; Animals; Cimetidine; Drug Therapy, Combination; Guinea Pigs; Histamine H1 Antagonists;

1984
The role of histamine H-receptors in the anaphylactic histamine release from human basophilic leukocytes.
    Archivum immunologiae et therapiae experimentalis, 1980, Volume: 28, Issue:6

    Topics: Anaphylaxis; Basophils; Cimetidine; Guanidines; Histamine Release; Humans; Imidazoles; Impromidine;

1980
The initial phase of the dextran-induced anaphylactoid reaction in the rat: a comparison of inhibitors of the blood pressure fall.
    Acta pharmacologica et toxicologica, 1982, Volume: 51, Issue:2

    Topics: Anaphylaxis; Animals; Blood Pressure; Cimetidine; Dextrans; Enzyme Precursors; Kininogens; Lysergic

1982
Changes in bronchial anaphylactic reactivity induced in guinea-pigs by long-term treatment with histamine H2-agents.
    British journal of pharmacology, 1984, Volume: 82, Issue:1

    Topics: Anaphylaxis; Animals; Bronchi; Cimetidine; Dimaprit; Female; Guinea Pigs; Histamine H2 Antagonists;

1984
Acute systemic anaphylaxis in adult domestic fowl: evidence for the protective role of H2-histaminergic and beta 2-adrenergic receptors.
    American journal of veterinary research, 1980, Volume: 41, Issue:1

    Topics: Anaphylaxis; Animals; Blood Pressure; Carotid Arteries; Chickens; Chromones; Cimetidine; Dimaprit; E

1980
A specific antihistaminic premedication anti H1 anti H2 for pediatric anesthesia.
    Acta anaesthesiologica Belgica, 1984, Volume: 35 Suppl

    Topics: Anaphylaxis; Anesthesia, General; Child; Child, Preschool; Cimetidine; Drug Therapy, Combination; Fe

1984
Life-threatening idiopathic anaphylaxis associated with hyperimmunoglobulinemia E.
    The American journal of medicine, 1984, Volume: 76, Issue:3

    Topics: Anaphylaxis; Cimetidine; Coronary Disease; Diphenhydramine; Humans; Hydroxyzine; Hypergammaglobuline

1984
The role of histamine in the physiologic alterations of IgE anaphylaxis in the rabbit.
    Immunopharmacology, 1984, Volume: 7, Issue:2

    Topics: Airway Resistance; Anaphylaxis; Animals; Antigens; Cimetidine; Female; Hemodynamics; Histamine; Hist

1984
The effect of H2-blocking agents on systemic anaphylaxis in guinea pigs.
    The American review of respiratory disease, 1980, Volume: 121, Issue:4

    Topics: Anaphylaxis; Animals; Cimetidine; Functional Residual Capacity; Guanidines; Guinea Pigs; Lung; Lung

1980
Cimetidine and hypersensitivity.
    Annals of internal medicine, 1983, Volume: 98, Issue:1

    Topics: Anaphylaxis; Cimetidine; Drug Hypersensitivity; Guanidines; Humans

1983
Cimetidine-induced anaphylaxis.
    Annals of internal medicine, 1982, Volume: 97, Issue:3

    Topics: Anaphylaxis; Cimetidine; Forced Expiratory Volume; Guanidines; Humans; Infusions, Parenteral; Male;

1982
Deleterious effects of cimetidine in the presence of histamine on coronary circulation. Possible clinical implications in anaphylactic states in individuals with coronary heart disease.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1982, Volume: 180, Issue:3

    Topics: Anaphylaxis; Animals; Cimetidine; Coronary Circulation; Coronary Disease; Drug Interactions; Female;

1982
Possible participation of histamine H3-receptors in the regulation of anaphylactic histamine release from isolated rat peritoneal mast cells.
    Japanese journal of pharmacology, 1994, Volume: 66, Issue:2

    Topics: Anaphylaxis; Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Cimetidine; Dimaprit; D

1994
Dimaprit, a histamine H2-agonist, inhibits anaphylactic histamine release from mast cells and the decreased release is restored by thioperamide (H3-antagonist), but not by cimetidine (H2-antagonist).
    Japanese journal of pharmacology, 1993, Volume: 62, Issue:1

    Topics: Anaphylaxis; Animals; Anticonvulsants; Betahistine; Cimetidine; Dimaprit; Histamine H2 Antagonists;

1993
The effects of combined histamine and platelet-activating factor antagonism on systemic anaphylaxis induced by immunoglobulin E in the rabbit.
    The American review of respiratory disease, 1993, Volume: 147, Issue:5

    Topics: Airway Resistance; Anaphylaxis; Animals; Azepines; Basophil Degranulation Test; Blood Pressure; Chlo

1993
Release of calcitonin gene-related peptide in cardiac anaphylaxis.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Anaphylaxis; Animals; Calcitonin Gene-Related Peptide; Cimetidine; Cor

1997
Prophylaxis for anaphylactoid reactions in high risk patients receiving radiopaque contrast media.
    Surgical neurology, 1997, Volume: 48, Issue:3

    Topics: Anaphylaxis; Anti-Allergic Agents; Anti-Inflammatory Agents; Bronchodilator Agents; Cimetidine; Cont

1997
Value of baseline levels in assessing tryptase release.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2000, Volume: 49 Suppl 1

    Topics: Anaphylaxis; Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthroplasty, Replacement; Chymases; Cim

2000
Absence of mast cell involvement in active systemic anaphylaxis in rats.
    European journal of pharmacology, 2001, Nov-02, Volume: 430, Issue:2-3

    Topics: Anaphylaxis; Animals; Blood Pressure; Cell Degranulation; Chlorpheniramine; Cimetidine; Dextrans; Ge

2001
The effects of H1 and H2 receptor antagonism on the response of monkey skin to intradermal histamine, reverse-type anaphylaxis, and passive cutaneous anaphylaxis.
    The Journal of allergy and clinical immunology, 1979, Volume: 63, Issue:6

    Topics: Anaphylaxis; Animals; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Immunologic; Haplorh

1979
Acceleration of idioventricular rhythms by histamine in guinea pig heart: mediation by H2 receptors.
    Circulation research, 1979, Volume: 44, Issue:6

    Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Chlorpheniramine; Cimetidine; Dose-Response Relationship

1979
H2 receptor mediated inhibition of immediate type hypersensitivity reactions in vivo.
    The American review of respiratory disease, 1978, Volume: 117, Issue:3

    Topics: Anaphylaxis; Animals; Burimamide; Cimetidine; Feedback; Guinea Pigs; Lung; Lung Volume Measurements;

1978
Anaphylactoid reaction to iopamiro (after pretreatment).
    Australasian radiology, 1992, Volume: 36, Issue:2

    Topics: Anaphylaxis; Cimetidine; Humans; Iopamidol; Male; Middle Aged; Prednisone; Premedication; Promethazi

1992
Effect of PAF-acether antagonists on active anaphylactic mouse paw edema.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Anaphylaxis; Animals; A

1991
Characterization of cardiovascular events mediated by platelet activating factor during systemic anaphylaxis.
    Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:6

    Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Azepines; Blood Pressure; Cardiac Output; Cimetidine; El

1990
Is cimetidine indicated in the treatment of acute anaphylactic shock?
    Anesthesia and analgesia, 1990, Volume: 71, Issue:1

    Topics: Anaphylaxis; Cimetidine; Humans

1990
Experimental renal anaphylaxis: release of histamine and study of its effect on renal perfusion.
    Agents and actions, 1987, Volume: 20, Issue:3-4

    Topics: Anaphylaxis; Animals; Cimetidine; Guinea Pigs; Histamine; Histamine Release; Immune Sera; Immunoglob

1987
Effects of antihistamines on the cardiopulmonary changes due to canine anaphylaxis.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 64, Issue:1

    Topics: Anaphylaxis; Animals; Antigens, Helminth; Ascaris; Chlorpheniramine; Cimetidine; Dogs; Heart; Hemody

1988
Activation of the third complement component (C3) and C3a generation in cardiac anaphylaxis: histamine release and associated inotropic and chronotropic effects.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3

    Topics: Anaphylaxis; Animals; Cimetidine; Complement Activation; Complement C3; Complement C3a; Guinea Pigs;

1988
Histamine 2 receptor blocker in the treatment of protamine related anaphylactoid reactions: two case reports.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1989, Volume: 36, Issue:4

    Topics: Adult; Anaphylaxis; Cimetidine; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Protami

1989
Cimetidine in anaphylactic shock refractory to standard therapy.
    Anesthesia and analgesia, 1989, Volume: 69, Issue:2

    Topics: Anaphylaxis; Cefuroxime; Cephalosporins; Cimetidine; Female; Humans; Intraoperative Complications; M

1989
Cimetidine in the treatment of refractory anaphylaxis.
    Annals of allergy, 1989, Volume: 63, Issue:3

    Topics: Anaphylaxis; Cefuroxime; Cimetidine; Drug Hypersensitivity; Female; Flushing; Humans; Hypotension; I

1989
Protective effects of histamine H1 and H2 antagonists, adenosine and hydrocortisone on cardiac anaphylaxis.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:1

    Topics: Adenosine; Aminopyridines; Anaphylaxis; Animals; Arrhythmias, Cardiac; Cardiac Output; Cimetidine; G

1989
Dissociation of cimetidine effects on inotropic and chronotropic action in cardiac anaphylaxis.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:2

    Topics: Anaphylaxis; Animals; Cimetidine; Guinea Pigs; Heart Rate; Histamine; In Vitro Techniques; Myocardia

1989
Prophylaxis against repeated radiocontrast media reactions in 857 cases. Adverse experience with cimetidine and safety of beta-adrenergic antagonists.
    Archives of internal medicine, 1985, Volume: 145, Issue:12

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Anaphylaxis; Cimetidine; Contrast Media; Diphenhydra

1985
[Premedication with H1- and H2-receptor antagonists for intravenous urography using contrast media].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1986, Volume: 144, Issue:2

    Topics: Adult; Aged; Anaphylaxis; Cimetidine; Contrast Media; Dimethindene; Female; Histamine H1 Antagonists

1986
Repeat chemonucleolysis.
    Clinical orthopaedics and related research, 1986, Issue:206

    Topics: Adolescent; Adult; Anaphylaxis; Chymopapain; Cimetidine; Female; Follow-Up Studies; Histamine H1 Ant

1986
The antianaphylactic action of histamine H2-receptor agonists in the guinea-pig isolated heart.
    British journal of pharmacology, 1987, Volume: 90, Issue:3

    Topics: Anaphylaxis; Animals; Cimetidine; Dimaprit; Female; Guinea Pigs; Heart; Heart Rate; Histamine; Hista

1987
Efficacy of histamine H1 and H2 receptor blockers in the anesthetic management during operation for hydatid cysts of liver and lungs.
    Southern medical journal, 1988, Volume: 81, Issue:8

    Topics: Adult; Anaphylaxis; Anesthesia; Blood Pressure; Bronchial Spasm; Central Venous Pressure; Cimetidine

1988
Intravenous cimetidine as an effective treatment for systemic anaphylaxis and acute allergic skin reactions.
    Annals of allergy, 1987, Volume: 58, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aged; Anaphylaxis; Child; Cimetidine; Dermatitis, Contact; Drug Ev

1987
The effect of calcium on cardiac anaphylaxis in guinea-pig Langendorff heart preparations.
    Agents and actions, 1985, Volume: 16, Issue:5

    Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Calcium; Cardiovascular Diseases; Cimetidine; Coronary C

1985