cimetidine has been researched along with Amenorrhea in 3 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Amenorrhea: Absence of menstruation.
| Excerpt | Relevance | Reference |
|---|---|---|
| " e) The gynaecomastia, galactorrhoea, amenorrhoea and impotence--reported only after long-term cimetidine treatment--can probably be attributed to the specific antiandrogen receptor property of CMT." | 4.77 | [Dysfunction of the hypothalamo-hypophyseal-gonadal axis induced by histamine H2 antagonists. Review of the literature and personal observations]. ( Biagi, P; Milani, G, 1985) |
| "The effect of acute intravenous injection of 400mg cimetidine, a histamine H2-receptor antagonist, on prolactin (PRL) secretion was investigated in women with normal menstrual cycles (n = 12) and normoprolactinemic secondary amenorrhea (n = 10)." | 3.66 | [Effect of a histamine H2-receptor antagonist, cimetidine, on prolactin secretion in women]. ( Kumasaka, T; Masaoka, K; Niibe, T; Saito, M, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Masaoka, K | 1 |
| Niibe, T | 1 |
| Kumasaka, T | 1 |
| Saito, M | 1 |
| Barth, JA | 1 |
| Biagi, P | 1 |
| Milani, G | 1 |
1 review available for cimetidine and Amenorrhea
| Article | Year |
|---|---|
[Dysfunction of the hypothalamo-hypophyseal-gonadal axis induced by histamine H2 antagonists. Review of the literature and personal observations].
Topics: Amenorrhea; Androgens; Cimetidine; Erectile Dysfunction; Female; Follicle Stimulating Hormone; Galac | 1985 |
2 other studies available for cimetidine and Amenorrhea
| Article | Year |
|---|---|
[Effect of a histamine H2-receptor antagonist, cimetidine, on prolactin secretion in women].
Topics: Adult; Amenorrhea; Cimetidine; Dose-Response Relationship, Drug; Female; Humans; Prolactin | 1983 |
[Can ulcer treatment with cimetidine and other H2 receptor antagonists induce sexual dysfunctions (impotence) and other endocrine disorders?].
Topics: Amenorrhea; Cimetidine; Erectile Dysfunction; Female; Gynecomastia; Humans; Male; Peptic Ulcer; Risk | 1991 |