cimetidine has been researched along with Alzheimer Disease in 7 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (14.29) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 5 (71.43) | 24.3611 |
2020's | 1 (14.29) | 2.80 |
Authors | Studies |
---|---|
Tang, H | 3 |
Zhao, LZ | 1 |
Zhao, HT | 2 |
Huang, SL | 1 |
Zhong, SM | 2 |
Qin, JK | 1 |
Chen, ZF | 2 |
Huang, ZS | 1 |
Liang, H | 2 |
Wang, ZY | 1 |
Di Pietro, O | 1 |
Pérez-Areales, FJ | 2 |
Juárez-Jiménez, J | 1 |
Espargaró, A | 2 |
Clos, MV | 1 |
Pérez, B | 3 |
Lavilla, R | 1 |
Sabaté, R | 2 |
Luque, FJ | 1 |
Muñoz-Torrero, D | 2 |
Wei, S | 1 |
Chen, W | 1 |
Qin, J | 1 |
Huangli, Y | 1 |
Wang, L | 1 |
Shen, Y | 1 |
Turcu, AL | 2 |
Barniol-Xicota, M | 1 |
Pont, C | 1 |
Pivetta, D | 1 |
Bartolini, M | 1 |
De Simone, A | 1 |
Andrisano, V | 1 |
Sureda, FX | 2 |
Vázquez, S | 2 |
Companys-Alemany, J | 1 |
Phillips, MB | 1 |
Patel, DS | 1 |
Griñán-Ferré, C | 1 |
Loza, MI | 1 |
Brea, JM | 1 |
Soto, D | 1 |
Kurnikova, MG | 1 |
Johnson, JW | 1 |
Pallàs, M | 1 |
Larson, EB | 1 |
Reifler, BV | 1 |
Sumi, SM | 1 |
Canfield, CG | 1 |
Chinn, NM | 1 |
7 other studies available for cimetidine and Alzheimer Disease
Article | Year |
---|---|
Hybrids of oxoisoaporphine-tacrine congeners: novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Aporphines; Blood- | 2011 |
Novel oxoisoaporphine-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Aporphines; Binding Sites; Blood-Bra | 2012 |
Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholinesterase Inhibitors; Cholinesterases; Dose-Response | 2014 |
Multitarget-directed oxoisoaporphine derivatives: Anti-acetylcholinesterase, anti-β-amyloid aggregation and enhanced autophagy activity against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Aporphines; Autophagy; Cholinesteras | 2016 |
A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors.
Topics: Acetylcholinesterase; Adamantane; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitor | 2019 |
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Recepto | 2022 |
Diagnostic evaluation of 200 elderly outpatients with suspected dementia.
Topics: Aged; Alzheimer Disease; Cimetidine; Cognition Disorders; Dementia; Depression; Follow-Up Studies; H | 1985 |