cimetidine has been researched along with Alloxan Diabetes in 3 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "ICRF-187, (+)-1,2-bis(3,5-dioxopiperazine-1-yl)propane, has been shown to protect against alloxan diabetes (el-Hage et al." | 3.67 | Mechanism of the protective activity of ICRF-187 against alloxan-induced diabetes in mice. ( Crouch, RK; el-Hage, A; Ferrans, VJ; Herman, EH; Yang, GC, 1986) |
| " Pharmacokinetic analysis was based on plasma and urine data concentrations." | 1.48 | The role of organic cation transporter 2 inhibitor cimetidine, experimental diabetes mellitus and metformin on gabapentin pharmacokinetics in rats. ( Baviera, AM; Benzi, JRL; de Moraes, NV; Stevens, JH; Yamamoto, PA, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benzi, JRL | 1 |
| Yamamoto, PA | 1 |
| Stevens, JH | 1 |
| Baviera, AM | 1 |
| de Moraes, NV | 1 |
| Liu, YC | 1 |
| Liu, HY | 1 |
| Yang, HW | 1 |
| Wen, T | 1 |
| Shang, Y | 1 |
| Liu, XD | 1 |
| Xie, L | 1 |
| Wang, GJ | 1 |
| el-Hage, A | 1 |
| Herman, EH | 1 |
| Yang, GC | 1 |
| Crouch, RK | 1 |
| Ferrans, VJ | 1 |
3 other studies available for cimetidine and Alloxan Diabetes
| Article | Year |
|---|---|
The role of organic cation transporter 2 inhibitor cimetidine, experimental diabetes mellitus and metformin on gabapentin pharmacokinetics in rats.
Topics: Amines; Animals; Cimetidine; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Gabapenti | 2018 |
Impaired expression and function of breast cancer resistance protein (Bcrp) in brain cortex of streptozocin-induced diabetic rats.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; | 2007 |
Mechanism of the protective activity of ICRF-187 against alloxan-induced diabetes in mice.
Topics: Alloxan; Animals; Blood Glucose; Chelating Agents; Cimetidine; Diabetes Mellitus, Experimental; Dime | 1986 |