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cimetidine and Allergic Reaction

cimetidine has been researched along with Allergic Reaction in 16 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Research Excerpts

ExcerptRelevanceReference
"Intravenous cimetidine treatment was prescribed for patients suffering from anaphylaxis, urticaria, pruritus, and contact dermatitis."7.67Intravenous cimetidine as an effective treatment for systemic anaphylaxis and acute allergic skin reactions. ( Asano, M; Au-Yong, TF; Kimura, S; Mayumi, H; Shimokawa, T; Yayama, T, 1987)
"Histamine was assayed spectrofluorometrically."5.27Function of prostaglandins, thromboxane A2, and histamine in hypersensitivity reaction to experimental bluetongue disease in calves. ( Anderson, GA; Emau, P; Giri, SN; Osburn, BI; Stott, JL, 1984)
"Intravenous cimetidine treatment was prescribed for patients suffering from anaphylaxis, urticaria, pruritus, and contact dermatitis."3.67Intravenous cimetidine as an effective treatment for systemic anaphylaxis and acute allergic skin reactions. ( Asano, M; Au-Yong, TF; Kimura, S; Mayumi, H; Shimokawa, T; Yayama, T, 1987)
"The role played by immunomodulation in allergy is critically reviewed."2.37Immunomodulators and allergy. ( Tassi, GC; Valcurone, G, 1985)
"Histamine was assayed spectrofluorometrically."1.27Function of prostaglandins, thromboxane A2, and histamine in hypersensitivity reaction to experimental bluetongue disease in calves. ( Anderson, GA; Emau, P; Giri, SN; Osburn, BI; Stott, JL, 1984)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199010 (62.50)18.7374
1990's2 (12.50)18.2507
2000's1 (6.25)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boia-Ferreira, M1
Moreno, KG1
Basílio, ABC1
da Silva, LP1
Vuitika, L1
Soley, B1
Wille, ACM1
Donatti, L1
Barbaro, KC1
Chaim, OM1
Gremski, LH1
Veiga, SS1
Senff-Ribeiro, A1
Jafarzadeh, A1
Nemati, M1
Khorramdelazad, H1
Hassan, ZM1
Arae, K1
Oboki, K1
Ohno, T1
Hirata, M1
Nakae, S1
Taguchi, H1
Saito, H1
Nakajima, T1
Kuraishi, Y1
Ohtsuka, E1
Nakano, T1
Kawai, S1
Andoh, T1
Nojima, H1
Kamimura, K1
Emau, P1
Giri, SN1
Anderson, GA1
Stott, JL1
Osburn, BI1
Pounder, RE1
Ting, S1
Zweiman, B1
Lavker, RM1
Dunsky, EH1
Heyneman, CA1
De Cock, W1
De Cree, J1
Verhaegen, H1
Marthan, R1
Crevel, H1
Guénard, H1
Savineau, JP1
Valcurone, G1
Tassi, GC1
Graver, LM1
Robertson, DA1
Levi, R1
Becker, CG1
Weksler, BB1
Gay, WA1
Mannaioni, PF1
Fantozzi, R1
Giannella, E1
Masini, E1
Leon, J1
Charap, A1
Duzman, E1
Shen, CD1
Mayumi, H1
Kimura, S1
Asano, M1
Shimokawa, T1
Au-Yong, TF1
Yayama, T1
Perdue, MH1
Gall, DG1

Reviews

4 reviews available for cimetidine and Allergic Reaction

ArticleYear
Immunomodulatory properties of cimetidine: Its therapeutic potentials for treatment of immune-related diseases.
    International immunopharmacology, 2019, Volume: 70

    Topics: Animals; Bone Resorption; Burns; Cimetidine; Dendritic Cells; Histamine; Humans; Hypersensitivity; I

2019
Histamine H2-receptor antagonists and gastric acid secretion.
    Pharmacology & therapeutics, 1984, Volume: 26, Issue:2

    Topics: Burimamide; Chemical Phenomena; Chemistry; Cimetidine; Duodenal Ulcer; Esophagitis, Peptic; Gastric

1984
Histamine2-antagonists in allergic disorders.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:6

    Topics: Asthma; Chlorpheniramine; Cimetidine; Clemastine; Clinical Trials as Topic; Drug Therapy, Combinatio

1994
Immunomodulators and allergy.
    Bollettino dell'Istituto sieroterapico milanese, 1985, Volume: 64, Issue:3

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Annexins; Antibody Specificity; Calcium Channel Blockers

1985

Trials

1 trial available for cimetidine and Allergic Reaction

ArticleYear
Efficacy of cimetidine/pyrilamine eyedrops. A dose response study with histamine challenge.
    Ophthalmology, 1986, Volume: 93, Issue:1

    Topics: Adult; Aminopyridines; Cimetidine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug

1986

Other Studies

11 other studies available for cimetidine and Allergic Reaction

ArticleYear
TCTP from
    Cells, 2019, 11-22, Volume: 8, Issue:12

    Topics: Animals; Biomarkers, Tumor; Cimetidine; Cromolyn Sodium; Dose-Response Relationship, Drug; Hypersens

2019
Cimetidine enhances antigen-specific IgE and Th2 cytokine production.
    Allergology international : official journal of the Japanese Society of Allergology, 2011, Volume: 60, Issue:3

    Topics: Animals; Cells, Cultured; Cimetidine; Cytokines; Epitopes; Histamine H2 Antagonists; Hypersensitivit

2011
Possible involvement of 5-lipoxygenase metabolite in itch-associated response of mosquito allergy in mice.
    Journal of pharmacological sciences, 2007, Volume: 105, Issue:1

    Topics: Animals; Arachidonate 5-Lipoxygenase; Betamethasone Valerate; Bridged Bicyclo Compounds, Heterocycli

2007
Function of prostaglandins, thromboxane A2, and histamine in hypersensitivity reaction to experimental bluetongue disease in calves.
    American journal of veterinary research, 1984, Volume: 45, Issue:9

    Topics: Animals; Bluetongue; Bluetongue virus; Cattle; Cattle Diseases; Cimetidine; Histamine; Hypersensitiv

1984
Effect of cimetidine on exogenous histamine inhibition of histamine release in vivo.
    Allergy, 1983, Volume: 38, Issue:1

    Topics: Biopsy; Cimetidine; Guanidines; Histamine Antagonists; Histamine Release; Humans; Hypersensitivity;

1983
Histamine receptor-bearing T lymphocytes in patients with allergy, autoimmune disease, or recurrent infection.
    Clinical immunology and immunopathology, 1978, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Autoimmune Diseases; Child; Child, Preschool; Cimetidine; Female; Humans; H

1978
Responsiveness to histamine in human sensitized airway smooth muscle.
    Respiration physiology, 1992, Volume: 90, Issue:2

    Topics: Aged; Analysis of Variance; Animals; Bronchi; Calcium; Cimetidine; Dose-Response Relationship, Drug;

1992
IgE-mediated hypersensitivity in human heart tissue: histamine release and functional changes.
    The Journal of allergy and clinical immunology, 1986, Volume: 77, Issue:5

    Topics: Adult; Cimetidine; Heart; Heart Rate; Histamine Release; Humans; Hypersensitivity; Immunoglobulin E;

1986
Pathophysiological significance of the distribution of histamine receptor sub-types: a proposed dual role for histamine in inflammation and type I hypersensitivity reactions.
    Agents and actions, 1988, Volume: 24, Issue:1-2

    Topics: Animals; Cimetidine; Female; Guinea Pigs; Histamine; Humans; Hypersensitivity; In Vitro Techniques;

1988
Intravenous cimetidine as an effective treatment for systemic anaphylaxis and acute allergic skin reactions.
    Annals of allergy, 1987, Volume: 58, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aged; Anaphylaxis; Child; Cimetidine; Dermatitis, Contact; Drug Ev

1987
Rat jejunal mucosal response to histamine and anti-histamines in vitro. Comparison with antigen-induced changes during intestinal anaphylaxis.
    Agents and actions, 1986, Volume: 19, Issue:1-2

    Topics: Animals; Cimetidine; Diphenhydramine; Histamine; Hypersensitivity; In Vitro Techniques; Intestinal M

1986