Page last updated: 2024-10-25

cimetidine and Alcoholism

cimetidine has been researched along with Alcoholism in 8 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)

Research Excerpts

ExcerptRelevanceReference
"A double-blind prospective controlled study designed to determine the effectiveness of the addition of cimetidine to standard treatment of acute alcoholic pancreatitis and to determine the importance of nasogastric suction in this disorder was undertaken."9.05Treatment of acute alcoholic pancreatitis: the roles of cimetidine and nasogastric suction. ( Banta, L; Lang, J; Loiudice, TA; Mehta, H, 1984)
"Clinical and experimental evidence has suggested that the use of cimetidine might be harmful to patients with acute pancreatitis."9.05A randomized trial comparing cimetidine to nasogastric suction in acute pancreatitis. ( Brugge, WR; Feinberg, LE; Goff, JS, 1982)
"A double-blind study was made of the comparative effectiveness of cimetidine in the treatment of acute alcoholic pancreatitis."9.04Cimetidine in the treatment of acute alcoholic pancreatitis. A randomized, double-blind study. ( Berk, JE; Gardner, L; Hoehler, FK; Meshkinpour, H; Molinari, MD, 1979)
"A double-blind prospective controlled study designed to determine the effectiveness of the addition of cimetidine to standard treatment of acute alcoholic pancreatitis and to determine the importance of nasogastric suction in this disorder was undertaken."5.05Treatment of acute alcoholic pancreatitis: the roles of cimetidine and nasogastric suction. ( Banta, L; Lang, J; Loiudice, TA; Mehta, H, 1984)
"Clinical and experimental evidence has suggested that the use of cimetidine might be harmful to patients with acute pancreatitis."5.05A randomized trial comparing cimetidine to nasogastric suction in acute pancreatitis. ( Brugge, WR; Feinberg, LE; Goff, JS, 1982)
"A double-blind study was made of the comparative effectiveness of cimetidine in the treatment of acute alcoholic pancreatitis."5.04Cimetidine in the treatment of acute alcoholic pancreatitis. A randomized, double-blind study. ( Berk, JE; Gardner, L; Hoehler, FK; Meshkinpour, H; Molinari, MD, 1979)
"We created acute pancreatitis in cats by instilling ethanol (20 ml of a 40% solution) into the stomach and then perfusing activated pancreatic enzymes through the main pancreatic duct."1.28Treatment of acute alcoholic pancreatitis in cats. ( Reber, HA; Singh, SM, 1990)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19907 (87.50)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Loiudice, TA1
Lang, J1
Mehta, H1
Banta, L1
Goff, JS1
Feinberg, LE1
Brugge, WR1
Jenike, MA1
Levy, JC1
Ferri, GL1
Sternini, C1
Bonora, G1
Vezzadini, P1
Labò, G1
Pardo, MP2
Hall, TB2
Meshkinpour, H1
Molinari, MD1
Gardner, L1
Berk, JE1
Hoehler, FK1
Singh, SM1
Reber, HA1
Miller, NS1
Goodwin, DW1
Jones, FC1
Gabrielli, WF1
Anand, MM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Asian Flushing Syndrome With Topical Alpha Agonists[NCT03497442]Early Phase 120 participants (Actual)Interventional2018-07-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for cimetidine and Alcoholism

ArticleYear
Genetic implications of the alcohol-induced flushing phenomenon in Orientals.
    Currents in alcoholism, 1981, Volume: 8

    Topics: Acetaldehyde; Alcoholism; Asian People; Cimetidine; Diphenhydramine; Ethanol; Female; Histamine; Hum

1981

Trials

4 trials available for cimetidine and Alcoholism

ArticleYear
Treatment of acute alcoholic pancreatitis: the roles of cimetidine and nasogastric suction.
    The American journal of gastroenterology, 1984, Volume: 79, Issue:7

    Topics: Acute Disease; Alcoholism; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Female; Humans

1984
A randomized trial comparing cimetidine to nasogastric suction in acute pancreatitis.
    Digestive diseases and sciences, 1982, Volume: 27, Issue:12

    Topics: Acute Disease; Alcoholism; Cimetidine; Clinical Trials as Topic; Guanidines; Humans; Length of Stay;

1982
Cimetidine in the treatment of acute alcoholic pancreatitis. A randomized, double-blind study.
    Gastroenterology, 1979, Volume: 77, Issue:4 Pt 1

    Topics: Acute Disease; Adult; Alcoholism; Amylases; Cimetidine; Clinical Trials as Topic; Double-Blind Metho

1979
Antihistamine blockade of alcohol-induced flushing in orientals.
    Journal of studies on alcohol, 1988, Volume: 49, Issue:1

    Topics: Adolescent; Adult; Alcoholism; Asian People; Blood Pressure; Cimetidine; Diphenhydramine; Ethanol; F

1988

Other Studies

3 other studies available for cimetidine and Alcoholism

ArticleYear
Physostigmine reversal of cimetidine-induced delirium and agitation.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:1

    Topics: Akathisia, Drug-Induced; Alcoholism; Cimetidine; Delirium; Female; Guanidines; Humans; Middle Aged;

1983
Effect of cimetidine on trypsin-like immunoreactivity in serum.
    Scandinavian journal of gastroenterology. Supplement, 1980, Volume: 62

    Topics: Adult; Aged; Alcoholism; Cimetidine; Female; Guanidines; Humans; Hyperlipoproteinemia Type IV; Male;

1980
Treatment of acute alcoholic pancreatitis in cats.
    Pancreas, 1990, Volume: 5, Issue:5

    Topics: Acute Disease; Alcoholism; Animals; Cats; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Fe

1990