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cimetidine and Alcoholic Cirrhosis

cimetidine has been researched along with Alcoholic Cirrhosis in 9 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Research Excerpts

ExcerptRelevanceReference
"In a 14-day multiple-dose study the pharmacokinetics of paroxetine was investigated in 12 patients with alcoholic cirrhosis and in 6 subjects without liver disease."3.68Pharmacokinetics of paroxetine in patients with cirrhosis. ( Almdal, TP; Bjerrum, K; Dalhoff, K; Keiding, S; Lund, J; Mengel, H, 1991)
" Cimetidine used in the ulcer therapy shows a certain antiandrogenic effect and after a longer time may evoke impotence and other undesirable andrological side-effects which we, however, did not realize in 4 weeks treatment periods."3.66[Andrologic anomalies in various gastrointestinal diseases]. ( Szarvas, F, 1983)
"Nine patients with compensated alcoholic and nonalcoholic cirrhosis of the liver and 11 patients with peptic ulcer received 200 mg of cimetidine orally and intravenously."3.66Cimetidine clearance and bioavailability in hepatic cirrhosis. ( Andreasen, PB; Døssing, M; Larsen, NE; Poulsen, HE; Sonne, J, 1981)
"Cimetidine clearance was diminished by about 30 p 100 in cirrhotic patients (0."2.65[Pharmacokinetics of cimetidine in ascitic cirrhotics]. ( Albin, H; Béraud, C; Couzigou, P; Fleury, B; Péhourcq, F; Vinçon, G, 1983)
"The disposition of cimetidine after oral and intravenous administration during multiple dosing was studied in 11 patients with Laennec's cirrhosis."1.27Cimetidine disposition in patients with Laennec's cirrhosis during multiple dosing therapy. ( Cello, JP; Oie, S, 1983)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's1 (11.11)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Navab, F1
Schiller, TD1
Slaton, D1
Cello, JP1
Oie, S1
Szarvas, F2
Greco, AV1
Modugno, I1
Altomonte, L1
Manna, R1
Rebuzzi, AG1
Ghirlanda, G1
Albin, H1
Couzigou, P1
Vinçon, G1
Péhourcq, F1
Fleury, B1
Béraud, C1
Wehr, M1
Schäfer, K1
Bode, JC1
Sonne, J1
Poulsen, HE1
Døssing, M1
Larsen, NE1
Andreasen, PB1
Dalhoff, K1
Almdal, TP1
Bjerrum, K1
Keiding, S1
Mengel, H1
Lund, J1

Reviews

1 review available for cimetidine and Alcoholic Cirrhosis

ArticleYear
Management of variceal hemorrhage.
    Southern medical journal, 1984, Volume: 77, Issue:10

    Topics: Blood Transfusion; Central Venous Pressure; Cimetidine; Emergencies; Esophageal and Gastric Varices;

1984

Trials

1 trial available for cimetidine and Alcoholic Cirrhosis

ArticleYear
[Pharmacokinetics of cimetidine in ascitic cirrhotics].
    Gastroenterologie clinique et biologique, 1983, Volume: 7, Issue:3

    Topics: Adult; Aged; Ascites; Cimetidine; Female; Guanidines; Humans; Kinetics; Liver Cirrhosis, Alcoholic;

1983

Other Studies

7 other studies available for cimetidine and Alcoholic Cirrhosis

ArticleYear
Cimetidine disposition in patients with Laennec's cirrhosis during multiple dosing therapy.
    European journal of clinical pharmacology, 1983, Volume: 25, Issue:2

    Topics: Adult; Biological Availability; Cimetidine; Creatinine; Humans; Kinetics; Liver Cirrhosis, Alcoholic

1983
[Andrologic anomalies in various gastrointestinal diseases].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1983, Aug-01, Volume: 38, Issue:15

    Topics: Cimetidine; Crohn Disease; Cystic Fibrosis; Erectile Dysfunction; Estradiol; Gastrointestinal Diseas

1983
Prolactin release in liver cirrhosis with impaired glucose tolerance (IGT).
    Endokrinologie, 1981, Volume: 78, Issue:1

    Topics: Adult; Blood Glucose; Cimetidine; Glucose Tolerance Test; Humans; Kinetics; Liver Cirrhosis, Alcohol

1981
[Granulocytopenia with cimetidine therapy (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1980, Nov-07, Volume: 105, Issue:45

    Topics: Adult; Agranulocytosis; Bone Marrow; Cimetidine; Guanidines; Humans; Liver Cirrhosis, Alcoholic; Mal

1980
Cimetidine clearance and bioavailability in hepatic cirrhosis.
    Clinical pharmacology and therapeutics, 1981, Volume: 29, Issue:2

    Topics: Administration, Oral; Aged; Biological Availability; Cimetidine; Female; Guanidines; Humans; Injecti

1981
Pharmacokinetics of paroxetine in patients with cirrhosis.
    European journal of clinical pharmacology, 1991, Volume: 41, Issue:4

    Topics: Adult; Aged; Cimetidine; Disulfiram; Drug Interactions; Female; Half-Life; Humans; Liver Cirrhosis,

1991
[Andrological abnormalities in internal diseases and following drug therapy].
    Andrologia, 1987, Volume: 19 Spec No

    Topics: Cimetidine; Crohn Disease; Diabetes Complications; Diabetes Mellitus; Estradiol; Follicle Stimulatin

1987