cimetidine has been researched along with Alcoholic Cirrhosis in 9 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a 14-day multiple-dose study the pharmacokinetics of paroxetine was investigated in 12 patients with alcoholic cirrhosis and in 6 subjects without liver disease." | 3.68 | Pharmacokinetics of paroxetine in patients with cirrhosis. ( Almdal, TP; Bjerrum, K; Dalhoff, K; Keiding, S; Lund, J; Mengel, H, 1991) |
| " Cimetidine used in the ulcer therapy shows a certain antiandrogenic effect and after a longer time may evoke impotence and other undesirable andrological side-effects which we, however, did not realize in 4 weeks treatment periods." | 3.66 | [Andrologic anomalies in various gastrointestinal diseases]. ( Szarvas, F, 1983) |
| "Nine patients with compensated alcoholic and nonalcoholic cirrhosis of the liver and 11 patients with peptic ulcer received 200 mg of cimetidine orally and intravenously." | 3.66 | Cimetidine clearance and bioavailability in hepatic cirrhosis. ( Andreasen, PB; Døssing, M; Larsen, NE; Poulsen, HE; Sonne, J, 1981) |
| "Cimetidine clearance was diminished by about 30 p 100 in cirrhotic patients (0." | 2.65 | [Pharmacokinetics of cimetidine in ascitic cirrhotics]. ( Albin, H; Béraud, C; Couzigou, P; Fleury, B; Péhourcq, F; Vinçon, G, 1983) |
| "The disposition of cimetidine after oral and intravenous administration during multiple dosing was studied in 11 patients with Laennec's cirrhosis." | 1.27 | Cimetidine disposition in patients with Laennec's cirrhosis during multiple dosing therapy. ( Cello, JP; Oie, S, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Navab, F | 1 |
| Schiller, TD | 1 |
| Slaton, D | 1 |
| Cello, JP | 1 |
| Oie, S | 1 |
| Szarvas, F | 2 |
| Greco, AV | 1 |
| Modugno, I | 1 |
| Altomonte, L | 1 |
| Manna, R | 1 |
| Rebuzzi, AG | 1 |
| Ghirlanda, G | 1 |
| Albin, H | 1 |
| Couzigou, P | 1 |
| Vinçon, G | 1 |
| Péhourcq, F | 1 |
| Fleury, B | 1 |
| Béraud, C | 1 |
| Wehr, M | 1 |
| Schäfer, K | 1 |
| Bode, JC | 1 |
| Sonne, J | 1 |
| Poulsen, HE | 1 |
| Døssing, M | 1 |
| Larsen, NE | 1 |
| Andreasen, PB | 1 |
| Dalhoff, K | 1 |
| Almdal, TP | 1 |
| Bjerrum, K | 1 |
| Keiding, S | 1 |
| Mengel, H | 1 |
| Lund, J | 1 |
1 review available for cimetidine and Alcoholic Cirrhosis
| Article | Year |
|---|---|
Management of variceal hemorrhage.
Topics: Blood Transfusion; Central Venous Pressure; Cimetidine; Emergencies; Esophageal and Gastric Varices; | 1984 |
1 trial available for cimetidine and Alcoholic Cirrhosis
| Article | Year |
|---|---|
[Pharmacokinetics of cimetidine in ascitic cirrhotics].
Topics: Adult; Aged; Ascites; Cimetidine; Female; Guanidines; Humans; Kinetics; Liver Cirrhosis, Alcoholic; | 1983 |
7 other studies available for cimetidine and Alcoholic Cirrhosis
| Article | Year |
|---|---|
Cimetidine disposition in patients with Laennec's cirrhosis during multiple dosing therapy.
Topics: Adult; Biological Availability; Cimetidine; Creatinine; Humans; Kinetics; Liver Cirrhosis, Alcoholic | 1983 |
[Andrologic anomalies in various gastrointestinal diseases].
Topics: Cimetidine; Crohn Disease; Cystic Fibrosis; Erectile Dysfunction; Estradiol; Gastrointestinal Diseas | 1983 |
Prolactin release in liver cirrhosis with impaired glucose tolerance (IGT).
Topics: Adult; Blood Glucose; Cimetidine; Glucose Tolerance Test; Humans; Kinetics; Liver Cirrhosis, Alcohol | 1981 |
[Granulocytopenia with cimetidine therapy (author's transl)].
Topics: Adult; Agranulocytosis; Bone Marrow; Cimetidine; Guanidines; Humans; Liver Cirrhosis, Alcoholic; Mal | 1980 |
Cimetidine clearance and bioavailability in hepatic cirrhosis.
Topics: Administration, Oral; Aged; Biological Availability; Cimetidine; Female; Guanidines; Humans; Injecti | 1981 |
Pharmacokinetics of paroxetine in patients with cirrhosis.
Topics: Adult; Aged; Cimetidine; Disulfiram; Drug Interactions; Female; Half-Life; Humans; Liver Cirrhosis, | 1991 |
[Andrological abnormalities in internal diseases and following drug therapy].
Topics: Cimetidine; Crohn Disease; Diabetes Complications; Diabetes Mellitus; Estradiol; Follicle Stimulatin | 1987 |