cimetidine has been researched along with Alcohol Drinking in 34 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.
Excerpt | Relevance | Reference |
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"Antacid (AA) in a very low dose (88 mmol/day) was compared to the standard 800-mg dose of cimetidine in healing duodenal ulcers." | 9.07 | Very-low dose antacid in treatment of duodenal ulcer. Comparison with cimetidine. ( Cordeiro, F; Jorge, JL; Lyra, LG; Massuda, HK; Miszputen, SJ; Modena, JL; Silva, EP; Toletino, MM; Vieira, FE; Zaterka, S, 1991) |
"Nizatidine, a new H2-receptor antagonist for the treatment of duodenal ulcer disease, was compared with cimetidine in an 8-wk, randomized, double-blind, multicenter clinical trial." | 9.06 | Comparison of nizatidine and cimetidine as once-nightly treatment of acute duodenal ulcer. Nizatidine Multicenter Duodenal Ulcer Study Group. ( Cherner, JA; Cloud, ML; Latz, JE; Offen, WW, 1989) |
"Data were combined for statistical analysis from four European trials comparing enprostil (35 micrograms twice daily) with cimetidine (400 mg twice daily) in the treatment of duodenal ulcer, using a double-blind, randomized design with endoscopic control." | 9.06 | Comparison of enprostil and cimetidine in active duodenal ulcer disease. Summary of pooled European studies. ( Winters, L, 1986) |
"Seventy-two patients with endoscopically proven gastric ulcers were entered into a prospective controlled trial to assess the efficacy of ranitidine and cimetidine in ulcer healing." | 9.05 | Ranitidine in the treatment of gastric ulceration. ( Bornman, PC; Gilinsky, NH; Girdwood, AH; Lucke, W; Marks, IN; Mee, AS; Tobias, P; Wright, JP, 1982) |
"The aim of the study was to compare the effectiveness of ranitidine and cimetidine in accelerating the healing of chronic gastric ulcer." | 9.05 | Comparison of ranitidine and cimetidine in the treatment of chronic gastric ulcer. A double-blind trial. ( Barr, GD; Cowen, AE; Kellow, JE; Piper, DW; Ward, M; Wood, L, 1983) |
"In a randomized multicentre study of 149 patients with gastric ulcer the effect of 1000 mg cimetidine daily applied in four separate doses was compared to that of 400 mg cimetidine twice a day." | 9.05 | [2 or 4 daily doses of cimetidine in the treatment of gastric ulcer?]. ( Backwinkel, KP; Beckenbach, HP; Bock, H; Feyerabend, H; Mares, A; Pelz, W; Pistauer, H; Rohner, HG; Weiss, W; Wienbeck, M, 1984) |
"Thirty-seven patients with chronic duodenal ulceration were entered into an endoscopically controlled trial of cimetidine (Tagamet) versus tri-potassium di-citrato bismuthate (De-Nol)." | 9.05 | Double-blind trial of cimetidine versus tri-potassium di-citrato bismuthate in chronic duodenal ulceration. ( Cowen, A; Pollard, EJ; Ward, M, 1981) |
"The efficacy of misoprostol (a synthetic analogue of prostaglandin E1) and cimetidine in the treatment of duodenal ulcer was evaluated." | 9.05 | Comparison of misoprostol and cimetidine in the treatment of duodenal ulcer. ( Fich, A; Goldin, E; Ligumsky, M; Rachmilewitz, D; Zimmerman, J, 1985) |
"The efficacy and tolerance of misoprostol a synthetic prostaglandin E1 analogue-and of cimetidine were evaluated in the treatment of duodenal ulcer following a double blind multicenter design." | 9.05 | [Misoprostol and cimetidine in the treatment of duodenal ulcer. A multicenter Swiss double-blind study]. ( Aenishänslin, W; Bärlocher, C; Bernoulli, R; Egger, G; Eisner, M; Fumagalli, I; Güller, R; Leuthold, E; Osterkorn, K; Pelloni, S, 1985) |
"Forty patients with chronic duodenal ulcer who had healed endoscopically with a 6-week course of cimetidine were randomized double blind to 1 year of either placebo or cimetidine tablets 400 mg bid (20 patients in each group)." | 9.04 | Long-term cimetidine in duodenal ulcer disease. ( Hansky, J; Korman, MG, 1979) |
"Healing rates were examined retrospectively in 124 outpatients with peptic ulcer who had received cimetidine for at least four weeks." | 7.67 | Unsuccessful cimetidine treatment of peptic ulcer: analysis of the factors involved. ( Angelini, GP; Celli, L; Granelli, P, 1984) |
"Antacid (AA) in a very low dose (88 mmol/day) was compared to the standard 800-mg dose of cimetidine in healing duodenal ulcers." | 5.07 | Very-low dose antacid in treatment of duodenal ulcer. Comparison with cimetidine. ( Cordeiro, F; Jorge, JL; Lyra, LG; Massuda, HK; Miszputen, SJ; Modena, JL; Silva, EP; Toletino, MM; Vieira, FE; Zaterka, S, 1991) |
"Nizatidine, a new H2-receptor antagonist for the treatment of duodenal ulcer disease, was compared with cimetidine in an 8-wk, randomized, double-blind, multicenter clinical trial." | 5.06 | Comparison of nizatidine and cimetidine as once-nightly treatment of acute duodenal ulcer. Nizatidine Multicenter Duodenal Ulcer Study Group. ( Cherner, JA; Cloud, ML; Latz, JE; Offen, WW, 1989) |
"Data were combined for statistical analysis from four European trials comparing enprostil (35 micrograms twice daily) with cimetidine (400 mg twice daily) in the treatment of duodenal ulcer, using a double-blind, randomized design with endoscopic control." | 5.06 | Comparison of enprostil and cimetidine in active duodenal ulcer disease. Summary of pooled European studies. ( Winters, L, 1986) |
"Seventy-two patients with endoscopically proven gastric ulcers were entered into a prospective controlled trial to assess the efficacy of ranitidine and cimetidine in ulcer healing." | 5.05 | Ranitidine in the treatment of gastric ulceration. ( Bornman, PC; Gilinsky, NH; Girdwood, AH; Lucke, W; Marks, IN; Mee, AS; Tobias, P; Wright, JP, 1982) |
"The aim of the study was to compare the effectiveness of ranitidine and cimetidine in accelerating the healing of chronic gastric ulcer." | 5.05 | Comparison of ranitidine and cimetidine in the treatment of chronic gastric ulcer. A double-blind trial. ( Barr, GD; Cowen, AE; Kellow, JE; Piper, DW; Ward, M; Wood, L, 1983) |
"Previous studies have shown that approximately 50% and 70% of duodenal ulcers heal after 2 and 4 wk, respectively, of cimetidine, and at least one-third heal after 4 wk of placebo." | 5.05 | Accurate prediction of duodenal-ulcer healing rate by discriminant analysis. ( Koo, J; Lam, SK, 1983) |
"In a randomized multicentre study of 149 patients with gastric ulcer the effect of 1000 mg cimetidine daily applied in four separate doses was compared to that of 400 mg cimetidine twice a day." | 5.05 | [2 or 4 daily doses of cimetidine in the treatment of gastric ulcer?]. ( Backwinkel, KP; Beckenbach, HP; Bock, H; Feyerabend, H; Mares, A; Pelz, W; Pistauer, H; Rohner, HG; Weiss, W; Wienbeck, M, 1984) |
"Thirty-seven patients with chronic duodenal ulceration were entered into an endoscopically controlled trial of cimetidine (Tagamet) versus tri-potassium di-citrato bismuthate (De-Nol)." | 5.05 | Double-blind trial of cimetidine versus tri-potassium di-citrato bismuthate in chronic duodenal ulceration. ( Cowen, A; Pollard, EJ; Ward, M, 1981) |
"The efficacy of misoprostol (a synthetic analogue of prostaglandin E1) and cimetidine in the treatment of duodenal ulcer was evaluated." | 5.05 | Comparison of misoprostol and cimetidine in the treatment of duodenal ulcer. ( Fich, A; Goldin, E; Ligumsky, M; Rachmilewitz, D; Zimmerman, J, 1985) |
"The efficacy and tolerance of misoprostol a synthetic prostaglandin E1 analogue-and of cimetidine were evaluated in the treatment of duodenal ulcer following a double blind multicenter design." | 5.05 | [Misoprostol and cimetidine in the treatment of duodenal ulcer. A multicenter Swiss double-blind study]. ( Aenishänslin, W; Bärlocher, C; Bernoulli, R; Egger, G; Eisner, M; Fumagalli, I; Güller, R; Leuthold, E; Osterkorn, K; Pelloni, S, 1985) |
"Forty patients with chronic duodenal ulcer who had healed endoscopically with a 6-week course of cimetidine were randomized double blind to 1 year of either placebo or cimetidine tablets 400 mg bid (20 patients in each group)." | 5.04 | Long-term cimetidine in duodenal ulcer disease. ( Hansky, J; Korman, MG, 1979) |
"To assess effects of repetitive alcohol drinking and pre-existing first-pass metabolism on the cimetidine-induced increase in blood alcohol concentrations, 20 healthy men (aged 20 to 40) of varied ethnicity and consuming less than 60 g alcohol per week underwent baseline quantitation of first-pass metabolism of alcohol." | 3.69 | Significant increase of blood alcohol by cimetidine after repetitive drinking of small alcohol doses. ( Baraona, E; Gupta, AM; Lieber, CS, 1995) |
"Healing rates were examined retrospectively in 124 outpatients with peptic ulcer who had received cimetidine for at least four weeks." | 3.67 | Unsuccessful cimetidine treatment of peptic ulcer: analysis of the factors involved. ( Angelini, GP; Celli, L; Granelli, P, 1984) |
" The effects of a minimum of 2 weeks of dosing with cimetidine, ranitidine and omeprazole were examined." | 1.30 | Omeprazole, ranitidine, and cimetidine have no effect on peak blood ethanol concentrations, first pass metabolism or area under the time-ethanol curve under 'real-life' drinking conditions. ( Brown, AS; James, OF, 1998) |
"Duodenal ulcer was found to relapse more frequently in patients with total serum pepsinogen more than 109 micrograms tyr X ml-1 X 24 h-1 and in patients with maximal acid output more than 60 mmol/h (Logrank test; both p less than 0." | 1.27 | Recurrence of duodenal ulcer under continuous antisecretory treatment: an approach to the detection of predictive markers. ( Battaglia, G; Burlina, A; Di Mario, F; Farini, R; Naccarato, R; Piccoli, A; Plebani, M; Vianello, F, 1984) |
" So far as can be assessed, however, none of these drug-disease associations represented adverse effects of cimetidine treatment; on the contrary, they resulted from cimetidine being used, knowingly or unknowingly, for treating the symptoms of various diseases or for alleviating adverse effects of other agents such as corticosteroids, non-steroidal anti-inflammatory drugs, and radiotherapy." | 1.27 | Postmarketing surveillance of the safety of cimetidine: 12 month mortality report. ( Colin-Jones, DG; Langman, MJ; Lawson, DH; Vessey, MP, 1983) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 24 (70.59) | 18.7374 |
1990's | 10 (29.41) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Schubert, TT | 1 |
Battaglia, G | 1 |
Farini, R | 1 |
Di Mario, F | 1 |
Piccoli, A | 1 |
Plebani, M | 1 |
Vianello, F | 1 |
Burlina, A | 1 |
Naccarato, R | 1 |
Thomas, JM | 1 |
Misiewicz, G | 1 |
Wright, JP | 1 |
Marks, IN | 1 |
Mee, AS | 1 |
Girdwood, AH | 1 |
Bornman, PC | 1 |
Gilinsky, NH | 1 |
Tobias, P | 1 |
Lucke, W | 1 |
Kellow, JE | 1 |
Barr, GD | 1 |
Cowen, AE | 1 |
Ward, M | 2 |
Wood, L | 1 |
Piper, DW | 2 |
Dobrilla, G | 1 |
de Pretis, G | 1 |
Piazzi, L | 1 |
Chilovi, F | 1 |
Comberlato, M | 1 |
Valentini, M | 1 |
Pastorino, A | 1 |
Vallaperta, P | 1 |
Lam, SK | 1 |
Koo, J | 1 |
Rohner, HG | 1 |
Wienbeck, M | 1 |
Feyerabend, H | 1 |
Backwinkel, KP | 1 |
Pelz, W | 1 |
Pistauer, H | 1 |
Bock, H | 1 |
Mares, A | 1 |
Weiss, W | 1 |
Beckenbach, HP | 1 |
Colin-Jones, DG | 1 |
Langman, MJ | 1 |
Lawson, DH | 1 |
Vessey, MP | 1 |
Rufín, F | 1 |
Llorens, P | 1 |
Altschiller, H | 1 |
Miranda, M | 1 |
Granelli, P | 1 |
Angelini, GP | 1 |
Celli, L | 1 |
Pollard, EJ | 1 |
Cowen, A | 1 |
Sonnenberg, A | 1 |
Müller-Lissner, SA | 1 |
Vogel, E | 1 |
Schmid, P | 1 |
Gonvers, JJ | 1 |
Peter, P | 1 |
Strohmeyer, G | 1 |
Blum, AL | 1 |
Hasan, M | 1 |
Sircus, W | 1 |
Gupta, AM | 1 |
Baraona, E | 1 |
Lieber, CS | 1 |
Parkhomenko, LK | 1 |
Radbil', OS | 1 |
Beil, W | 1 |
Sewing, KF | 1 |
Salim, AS | 2 |
Kawashima, O | 1 |
Yamauchi, M | 1 |
Maezawa, Y | 1 |
Toda, G | 1 |
Brown, AS | 1 |
James, OF | 1 |
Moshal, MG | 1 |
Spitaels, JM | 1 |
Khan, F | 1 |
Mason, J | 1 |
Naidoo, V | 1 |
Schlemmer, L | 1 |
Hansky, J | 1 |
Korman, MG | 2 |
Gangaidzo, I | 1 |
Kiire, C | 1 |
Mason, P | 1 |
Sitima, J | 1 |
Gwanzura, L | 1 |
Holdcroft, C | 1 |
Zaterka, S | 1 |
Cordeiro, F | 1 |
Lyra, LG | 1 |
Toletino, MM | 1 |
Miszputen, SJ | 1 |
Jorge, JL | 1 |
Silva, EP | 1 |
Vieira, FE | 1 |
Modena, JL | 1 |
Massuda, HK | 1 |
Cherner, JA | 1 |
Cloud, ML | 1 |
Offen, WW | 1 |
Latz, JE | 1 |
Gough, KR | 1 |
Bardhan, KD | 1 |
Crowe, JP | 1 |
Lee, FI | 1 |
Reed, PI | 1 |
Smith, RN | 1 |
Winters, L | 1 |
Fich, A | 1 |
Goldin, E | 1 |
Zimmerman, J | 1 |
Ligumsky, M | 1 |
Rachmilewitz, D | 1 |
Aenishänslin, W | 1 |
Bärlocher, C | 1 |
Bernoulli, R | 1 |
Egger, G | 1 |
Eisner, M | 1 |
Fumagalli, I | 1 |
Güller, R | 1 |
Leuthold, E | 1 |
Osterkorn, K | 1 |
Pelloni, S | 1 |
McIntosh, JH | 1 |
Hudson, HM | 1 |
Jewett, TC | 1 |
2 reviews available for cimetidine and Alcohol Drinking
Article | Year |
---|---|
Update in treatment of peptic ulcer disease.
Topics: Adult; Aged; Alcohol Drinking; Aluminum; Antacids; Anti-Ulcer Agents; Aspirin; Bismuth; Cimetidine; | 1984 |
Histamine H2-receptor antagonists in the short- and long-term treatment of duodenal ulcer.
Topics: Alcohol Drinking; Androgen Antagonists; Anti-Ulcer Agents; Bone Marrow; Cimetidine; Clinical Trials | 1984 |
18 trials available for cimetidine and Alcohol Drinking
Article | Year |
---|---|
Histamine H2-receptor antagonists in the short- and long-term treatment of duodenal ulcer.
Topics: Alcohol Drinking; Androgen Antagonists; Anti-Ulcer Agents; Bone Marrow; Cimetidine; Clinical Trials | 1984 |
Ranitidine in the treatment of gastric ulceration.
Topics: Aged; Alcohol Drinking; Antacids; Anti-Ulcer Agents; Aspirin; Cimetidine; Clinical Trials as Topic; | 1982 |
Comparison of ranitidine and cimetidine in the treatment of chronic gastric ulcer. A double-blind trial.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Anti-Ulcer Agents; Chronic Disease; Cimetidine; Clinical | 1983 |
Is ethanol metabolism affected by oral administration of cimetidine and ranitidine at therapeutic doses?
Topics: Administration, Oral; Adult; Alcohol Drinking; Alcohol Oxidoreductases; Cimetidine; Clinical Trials | 1984 |
Accurate prediction of duodenal-ulcer healing rate by discriminant analysis.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Cimetidine; Clinical Trials as Topic; Dose-Response Relat | 1983 |
[2 or 4 daily doses of cimetidine in the treatment of gastric ulcer?].
Topics: Alcohol Drinking; Cimetidine; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Random Al | 1984 |
Double-blind trial of cimetidine versus tri-potassium di-citrato bismuthate in chronic duodenal ulceration.
Topics: Adult; Aged; Alcohol Drinking; Anti-Ulcer Agents; Bismuth; Chronic Disease; Cimetidine; Clinical Tri | 1981 |
Predictors of duodenal ulcer healing and relapse.
Topics: Adult; Age Factors; Alcohol Drinking; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duo | 1981 |
[Effects of the histamine H2 receptor antagonist roxatidine acetate on stomach and liver alcohol dehydrogenase and serum alcohol level].
Topics: Adult; Alcohol Dehydrogenase; Alcohol Drinking; Animals; Cimetidine; Ethanol; Female; Guinea Pigs; H | 1993 |
Role of free radical scavengers in the management of refractory duodenal ulceration. A new approach.
Topics: Adult; Aged; Alcohol Drinking; Allopurinol; Cimetidine; Dimethyl Sulfoxide; Double-Blind Method; Dru | 1994 |
Factors affecting duodenal ulcer healing. Four double-blind trials in 193 patients.
Topics: Adult; Alcohol Drinking; Anti-Ulcer Agents; Bismuth; Cimetidine; Double-Blind Method; Duodenal Ulcer | 1982 |
Long-term cimetidine in duodenal ulcer disease.
Topics: Alcohol Drinking; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Endosco | 1979 |
Allopurinol and dimethyl sulfoxide improve treatment outcomes in smokers with peptic ulcer disease.
Topics: Adult; Alcohol Drinking; Allopurinol; Cimetidine; Dimethyl Sulfoxide; Double-Blind Method; Duodenal | 1992 |
Very-low dose antacid in treatment of duodenal ulcer. Comparison with cimetidine.
Topics: Adult; Alcohol Drinking; Aluminum Hydroxide; Antacids; Cimetidine; Coffee; Drug Administration Sched | 1991 |
Comparison of nizatidine and cimetidine as once-nightly treatment of acute duodenal ulcer. Nizatidine Multicenter Duodenal Ulcer Study Group.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Cimetidine; Creatinine; Double-Blin | 1989 |
Comparison of enprostil and cimetidine in active duodenal ulcer disease. Summary of pooled European studies.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Belgium; Cimetidine; Clinical Trials as Topic; Double-Bli | 1986 |
Comparison of misoprostol and cimetidine in the treatment of duodenal ulcer.
Topics: Adult; Aged; Alcohol Drinking; Cimetidine; Coffee; Double-Blind Method; Duodenal Ulcer; Duodenoscopy | 1985 |
[Misoprostol and cimetidine in the treatment of duodenal ulcer. A multicenter Swiss double-blind study].
Topics: Adult; Alcohol Drinking; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; | 1985 |
15 other studies available for cimetidine and Alcohol Drinking
Article | Year |
---|---|
Recurrence of duodenal ulcer under continuous antisecretory treatment: an approach to the detection of predictive markers.
Topics: Adolescent; Adult; Alcohol Drinking; Anti-Ulcer Agents; Benzodiazepinones; Blood Group Antigens; Cim | 1984 |
Postmarketing surveillance of the safety of cimetidine: 12 month mortality report.
Topics: Aged; Alcohol Drinking; Cimetidine; Colonic Neoplasms; England; Esophageal Neoplasms; Evaluation Stu | 1983 |
[Comparative study of 2 treatment schedules with cimetidine in patients with duodenal ulcer].
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Cimetidine; Drug Administration Schedule; Duodenal Ulcer; | 1983 |
Unsuccessful cimetidine treatment of peptic ulcer: analysis of the factors involved.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Anti-Inflammatory Agents; Child; Cimetidine; Female; Gast | 1984 |
The factors determining success or failure of cimetidine treatment of peptic ulcer.
Topics: Age Factors; Alcohol Drinking; Analgesics; Cimetidine; Drug Evaluation; Female; Guanidines; Humans; | 1981 |
Significant increase of blood alcohol by cimetidine after repetitive drinking of small alcohol doses.
Topics: Adult; Alcohol Drinking; Breath Tests; Cimetidine; Dose-Response Relationship, Drug; Ethanol; Histam | 1995 |
[Gastroesophageal reflux and bronchial asthma].
Topics: Adult; Alcohol Drinking; Aminophylline; Animals; Asthma; Bronchodilator Agents; Child; Cimetidine; D | 1994 |
Effects of cimetidine on blood ethanol levels after alcohol ingestion and genetic polymorphisms of sigma-alcohol dehydrogenase in Japanese.
Topics: Adult; Alcohol Dehydrogenase; Alcohol Drinking; Base Sequence; Cimetidine; Ethanol; Gastric Mucosa; | 1996 |
Omeprazole, ranitidine, and cimetidine have no effect on peak blood ethanol concentrations, first pass metabolism or area under the time-ethanol curve under 'real-life' drinking conditions.
Topics: Adult; Alcohol Drinking; Area Under Curve; Central Nervous System Depressants; Cimetidine; Ethanol; | 1998 |
Prospective endoscopic study of duodenal ulcer in Zimbabwean Blacks.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Cimetidine; Cohort Studies; Duodenal Ulcer; Duodenoscopy; | 1992 |
Cimetidine and ranitidine affect blood-alcohol levels.
Topics: Alcohol Dehydrogenase; Alcohol Drinking; Cimetidine; Drug Evaluation; Famotidine; Humans; Male; Rani | 1992 |
Cimetidine versus ranitidine.
Topics: Alcohol Drinking; Cimetidine; Duodenal Ulcer; Duodenoscopy; Humans; Patient Compliance; Ranitidine; | 1985 |
Drinking and smoking when taking H2-antagonists.
Topics: Alcohol Drinking; Cimetidine; Humans; Peptic Ulcer; Ranitidine; Recurrence; Smoking | 1985 |
Factors relevant to the prognosis of chronic duodenal ulcer.
Topics: Age Factors; Alcohol Drinking; Analgesics; Bismuth; Carbenoxolone; Chronic Disease; Cimetidine; Drug | 1985 |
Peptic ulcer in childhood.
Topics: Alcohol Drinking; Child; Child, Preschool; Cimetidine; Gastric Acid; Humans; Infant; Peptic Ulcer; S | 1985 |