cimetidine has been researched along with Age-Related Osteoporosis in 5 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "110 patients with benign gastric ulcer and concomitant joint diseases (rheumatoid arthritis, osteoarthrosis) were treated in a comparative short-term clinical trial to assess the relative efficacy of calcitonin (daily 100 MRC of salmon calcitonin intramuscularly), cimetidine (daily 1000 mg orally) and colloidal bismuth subcitrate (De-Nol-four times a day in doses of 5 ml diluted with 15 ml of water)." | 9.06 | Calcitonin versus cimetidine or De-Nol in gastric ulcer treatment. An endoscopically controlled trial. ( Badurski, J; Janke, A; Namiot, Z; Sajewicz, I; Stasiewicz, J, 1988) |
| "110 patients with benign gastric ulcer and concomitant joint diseases (rheumatoid arthritis, osteoarthrosis) were treated in a comparative short-term clinical trial to assess the relative efficacy of calcitonin (daily 100 MRC of salmon calcitonin intramuscularly), cimetidine (daily 1000 mg orally) and colloidal bismuth subcitrate (De-Nol-four times a day in doses of 5 ml diluted with 15 ml of water)." | 5.06 | Calcitonin versus cimetidine or De-Nol in gastric ulcer treatment. An endoscopically controlled trial. ( Badurski, J; Janke, A; Namiot, Z; Sajewicz, I; Stasiewicz, J, 1988) |
| "A patient with systemic mastocytosis, accompanied by gastric hypersecretion and duodenal ulcer, was treated with metiamide followed by daily cimetidine for 44 months." | 3.66 | Long-term treatment of systemic mastocytosis with histamine H2 receptor antagonists. ( Blumenthal, M; Gilbert, HS; Johnson, GJ; Roitman, B; Silvis, SE, 1980) |
| " This study was undertaken to determine whether patients with chronic use of H2-receptor antagonists (HRA) had demonstrable decreases in bone mineral density (BMD)." | 1.30 | Bone mineral density in patients taking H2-receptor antagonist. ( Adachi, Y; Iso, Y; Kitano, S; Matsumata, T; Shiota, E; Yoh, R, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xue, ST | 1 |
| Zhang, L | 1 |
| Xie, ZS | 1 |
| Jin, J | 1 |
| Guo, HF | 1 |
| Yi, H | 1 |
| Liu, ZY | 1 |
| Li, ZR | 1 |
| Johnson, GJ | 1 |
| Silvis, SE | 1 |
| Roitman, B | 1 |
| Blumenthal, M | 1 |
| Gilbert, HS | 1 |
| Grisso, JA | 1 |
| Kelsey, JL | 1 |
| O'Brien, LA | 1 |
| Miles, CG | 1 |
| Sidney, S | 1 |
| Maislin, G | 1 |
| LaPann, K | 1 |
| Moritz, D | 1 |
| Peters, B | 1 |
| Adachi, Y | 1 |
| Shiota, E | 1 |
| Matsumata, T | 1 |
| Iso, Y | 1 |
| Yoh, R | 1 |
| Kitano, S | 1 |
| Janke, A | 1 |
| Badurski, J | 1 |
| Stasiewicz, J | 1 |
| Sajewicz, I | 1 |
| Namiot, Z | 1 |
1 trial available for cimetidine and Age-Related Osteoporosis
| Article | Year |
|---|---|
Calcitonin versus cimetidine or De-Nol in gastric ulcer treatment. An endoscopically controlled trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Arthritis, Rheumatoid; Calc | 1988 |
4 other studies available for cimetidine and Age-Related Osteoporosis
| Article | Year |
|---|---|
Substituted benzothiophene and benzofuran derivatives as a novel class of bone morphogenetic Protein-2 upregulators: Synthesis, anti-osteoporosis efficacies in ovariectomized rats and a zebrafish model, and ADME properties.
Topics: Animals; Benzofurans; Bone Morphogenetic Protein 2; Caco-2 Cells; Disease Models, Animal; Dose-Respo | 2020 |
Long-term treatment of systemic mastocytosis with histamine H2 receptor antagonists.
Topics: Adult; Cimetidine; Duodenal Ulcer; Gastric Acid; Guanidines; Humans; Long-Term Care; Male; Metiamide | 1980 |
Risk factors for hip fracture in men. Hip Fracture Study Group.
Topics: Activities of Daily Living; Aged; Body Mass Index; Case-Control Studies; Cimetidine; Exercise; Hip F | 1997 |
Bone mineral density in patients taking H2-receptor antagonist.
Topics: Adult; Aged; Bone Density; Case-Control Studies; Cimetidine; Duodenal Ulcer; Famotidine; Female; His | 1998 |