cimetidine has been researched along with Adjuvant Arthritis in 3 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of cimetidine on rat adjuvant arthritis (AA) and rat osteoclast differentiation were studied." | 3.72 | The histamine H2-receptor antagonist, cimetidine, inhibits the articular osteopenia in rats with adjuvant-induced arthritis by suppressing the osteoclast differentiation induced by histamine. ( Nakamura, T; Ueno, K; Yamaura, K; Yano, S; Yonekawa, T, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamaura, K | 1 |
| Yonekawa, T | 1 |
| Nakamura, T | 1 |
| Yano, S | 1 |
| Ueno, K | 1 |
| Al-Haboubi, HA | 2 |
| Zeitlin, IJ | 2 |
3 other studies available for cimetidine and Adjuvant Arthritis
| Article | Year |
|---|---|
The histamine H2-receptor antagonist, cimetidine, inhibits the articular osteopenia in rats with adjuvant-induced arthritis by suppressing the osteoclast differentiation induced by histamine.
Topics: Animals; Arthritis, Experimental; Bone Density; Bone Resorption; Cartilage, Articular; Cell Differen | 2003 |
The actions of cimetidine hydrochloride and mepyramine maleate in rat adjuvant arthritis.
Topics: Aminopyridines; Animals; Arthritis; Arthritis, Experimental; Cimetidine; Guanidines; Male; Pyrilamin | 1982 |
The actions of cimetidine, mepyramine, indomethacin and aprotinin (Trasylol) on the inflammatory response in adjuvant rats [proceedings].
Topics: Aminopyridines; Animals; Aprotinin; Arthritis; Arthritis, Experimental; Cimetidine; Guanidines; Indo | 1979 |