cimetidine has been researched along with Adenoma in 12 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Adenoma: A benign epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recent evidence suggests that cimetidine given pre-operatively in primary hyperparathyroidism (1 degree HPT) might cause structural changes in parathyroid glands, while its suppressive effects on the disease are disputable." | 7.67 | The effect of cimetidine on parathyroid function and histopathology in primary hyperparathyroidism. ( Ikkos, DG; Nikou, AD; Pappas, AD; Singhellakis, PN; Sklivagou, NG; Sotsiou, FC; Vambouka, C, 1987) |
| "In twelve patients with primary hyperparathyroidism the raised parathyroid hormone (PTH) levels consistently returned to normal with cimetidine ("Tagamet"), 300 mg four times a day, orally." | 7.66 | Effect of cimetidine on circulating parathyroid hormone in primary hyperparathyroidism. ( Ackroyd, FW; Garcia, M; Sherwood, JK, 1980) |
| "We studied in vitro the presence of histamine and the effect of histamine and its antagonists on cAMP accumulation in parathyroid tissue (parathyroid adenoma or hyperplasia) from patients with primary hyperparathyroidism." | 7.66 | Histamine and human parathyroid adenoma: effect on adenosine 3',5'-monophosphate accumulation in vitro. ( Abbound, HE; Dousa, TP; Edis, AJ; Heath, H; Zimmerman, D, 1981) |
| "Cimetidine has been shown to lower circulating PTH levels effectively by causing an intraglandular rearrangement of PTH peptides in human parathyroid tissue in instances of primary hyperparathyroidism." | 5.27 | The preoperative use of cimetidine as a means of preventing symptomatic hypocalcemia following a parathyroid operation. ( Ackroyd, FW; Garcia, M; Minervini, D; Seiden, EF; Sherwood, JK; Willis, IH, 1983) |
| "The effect of cimetidine on basal and histamine-induced PTH secretion was tested using single cell suspensions obtained from (a) primary parathyroid adenomas, and (b) secondary hyperplastic parathyroid tissue from patients undergoing chronic hemodialysis." | 3.67 | Effect of cimetidine on basal and histamine-induced secretion of parathyroid hormone in vitro. ( Beyer, J; Krause, U; Rothmund, M; Schärfe, T; Wagner, PK, 1984) |
| "Recent evidence suggests that cimetidine given pre-operatively in primary hyperparathyroidism (1 degree HPT) might cause structural changes in parathyroid glands, while its suppressive effects on the disease are disputable." | 3.67 | The effect of cimetidine on parathyroid function and histopathology in primary hyperparathyroidism. ( Ikkos, DG; Nikou, AD; Pappas, AD; Singhellakis, PN; Sklivagou, NG; Sotsiou, FC; Vambouka, C, 1987) |
| "In twelve patients with primary hyperparathyroidism the raised parathyroid hormone (PTH) levels consistently returned to normal with cimetidine ("Tagamet"), 300 mg four times a day, orally." | 3.66 | Effect of cimetidine on circulating parathyroid hormone in primary hyperparathyroidism. ( Ackroyd, FW; Garcia, M; Sherwood, JK, 1980) |
| "We studied in vitro the presence of histamine and the effect of histamine and its antagonists on cAMP accumulation in parathyroid tissue (parathyroid adenoma or hyperplasia) from patients with primary hyperparathyroidism." | 3.66 | Histamine and human parathyroid adenoma: effect on adenosine 3',5'-monophosphate accumulation in vitro. ( Abbound, HE; Dousa, TP; Edis, AJ; Heath, H; Zimmerman, D, 1981) |
| "Cimetidine, which strongly stimulates prolactin release in healthy man, was unable to modify prolactin levels in prolactin-secreting pituitary adenomas." | 3.66 | Failure of drugs acting on H2-receptors to modify plasma prolactin levels in pituitary adenomas: evidence for a suprapituitary locus of action. ( Bertaccini, G; Ceda, GP; Scarpignato, C; Valenti, G, 1981) |
| "Cimetidine has been shown to lower circulating PTH levels effectively by causing an intraglandular rearrangement of PTH peptides in human parathyroid tissue in instances of primary hyperparathyroidism." | 1.27 | The preoperative use of cimetidine as a means of preventing symptomatic hypocalcemia following a parathyroid operation. ( Ackroyd, FW; Garcia, M; Minervini, D; Seiden, EF; Sherwood, JK; Willis, IH, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sherwood, JK | 2 |
| Ackroyd, FW | 2 |
| Garcia, M | 2 |
| Abbound, HE | 1 |
| Zimmerman, D | 1 |
| Edis, AJ | 1 |
| Heath, H | 1 |
| Dousa, TP | 1 |
| Brennan, MF | 1 |
| Bacchi Modena, A | 1 |
| Vadora, E | 1 |
| Fiaschetti, D | 1 |
| Micucci, G | 1 |
| Lombardozzi, L | 1 |
| Willis, IH | 1 |
| Minervini, D | 1 |
| Seiden, EF | 1 |
| Wagner, PK | 1 |
| Krause, U | 1 |
| Schärfe, T | 1 |
| Beyer, J | 1 |
| Rothmund, M | 1 |
| Klein, I | 1 |
| Lehotay, DC | 1 |
| Watson, CG | 1 |
| Rogerson, B | 1 |
| Levey, GS | 1 |
| Scarpignato, C | 1 |
| Valenti, G | 1 |
| Ceda, GP | 1 |
| Bertaccini, G | 1 |
| Gonzalez-Villapando, C | 1 |
| Szabo, M | 1 |
| Frohman, LA | 1 |
| Sasaki, H | 1 |
| Miyake, K | 1 |
| Okumura, M | 1 |
| Eimoto, T | 1 |
| Sotsiou, FC | 1 |
| Singhellakis, PN | 1 |
| Nikou, AD | 1 |
| Pappas, AD | 1 |
| Vambouka, C | 1 |
| Sklivagou, NG | 1 |
| Ikkos, DG | 1 |
| Kikuchi, Y | 1 |
| Seki, K | 1 |
| Momose, E | 1 |
| Kizawa, I | 1 |
| Oomori, K | 1 |
| Shima, K | 1 |
| Mukai, K | 1 |
| Kato, K | 1 |
1 review available for cimetidine and Adenoma
| Article | Year |
|---|---|
Primary hyperparathyroidism.
Topics: Adenoma; Aged; Cimetidine; Diphosphonates; Female; Humans; Hypercalcemia; Hyperparathyroidism; Male; | 1983 |
11 other studies available for cimetidine and Adenoma
| Article | Year |
|---|---|
Effect of cimetidine on circulating parathyroid hormone in primary hyperparathyroidism.
Topics: Adenoma; Administration, Oral; Aged; Cimetidine; Female; Guanidines; Humans; Hypercalcemia; Hyperpar | 1980 |
Histamine and human parathyroid adenoma: effect on adenosine 3',5'-monophosphate accumulation in vitro.
Topics: Adenoma; Cimetidine; Cyclic AMP; Female; Histamine; Humans; In Vitro Techniques; Isoproterenol; Male | 1981 |
[Role of H2 receptors in controlling prolactin release. Decreased response to cimetidine in patients with prolactin-secreting adenoma and idiopathic hyperprolactinemia].
Topics: Adenoma; Adult; Cimetidine; Female; Galactorrhea; Humans; Pituitary Neoplasms; Pregnancy; Prolactin; | 1984 |
The preoperative use of cimetidine as a means of preventing symptomatic hypocalcemia following a parathyroid operation.
Topics: Adenoma; Calcium; Cimetidine; Humans; Hypocalcemia; Parathyroid Glands; Parathyroid Hormone; Parathy | 1983 |
Effect of cimetidine on basal and histamine-induced secretion of parathyroid hormone in vitro.
Topics: Adenoma; Cimetidine; Dose-Response Relationship, Drug; Histamine; Humans; Hyperparathyroidism; Hyper | 1984 |
Human parathyroid adenoma adenylate cyclase: stimulation by histamine that is blocked by cimetidine.
Topics: Adenoma; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Cimetidine; Dose-Response Relationship, Dru | 1981 |
Failure of drugs acting on H2-receptors to modify plasma prolactin levels in pituitary adenomas: evidence for a suprapituitary locus of action.
Topics: Adenoma; Cimetidine; Female; Guanidines; Humans; Hypothalamus; Methylhistamines; Pituitary Neoplasms | 1981 |
Central nervous system-mediated stimulation of prolactin secretion by cimetidine, a histamine H2-receptor antagonist: impaired responsiveness in patients with prolactin-secreting tumors and idiopathic hyperprolactinemia.
Topics: Adenoma; Adolescent; Adult; Animals; Carbidopa; Cimetidine; Female; Guanidines; Humans; Levodopa; Ma | 1980 |
[Failure of cimetidine and etidronate disodium to suppress parathyroid hormone level and hypercalcemia in primary hyperparathyroidism].
Topics: Adenoma; Aged; Alkaline Phosphatase; Cimetidine; Etidronic Acid; Humans; Hypercalcemia; Hyperparathy | 1988 |
The effect of cimetidine on parathyroid function and histopathology in primary hyperparathyroidism.
Topics: Adenoma; Adolescent; Adult; Aged; Calcium; Cimetidine; Female; Humans; Hyperparathyroidism; Hyperpla | 1987 |
Establishment and characterization of a new human cultured cell line from a prolactin-secreting pituitary adenoma.
Topics: Adenoma; Bromocriptine; Cell Division; Cell Line; Cimetidine; Estradiol; Humans; Pituitary Neoplasms | 1985 |