cimetidine has been researched along with Acute Myelogenous Leukemia in 5 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Excerpt | Relevance | Reference |
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"A 76-year-old woman with acute myelogenous leukemia with approximately 65% myeloblasts on bone marrow examination was treated daily with a combination of 4 megaU of leukocyte interferon IM and 1,000 mg cimetidine PO." | 7.67 | Complete remission in a patient with acute myelogenous leukemia treated with leukocyte alpha-interferon and cimetidine. ( Ankerst, J; Fäldt, R; Flodgren, P; Nilsson, PG; Sjögren, HO, 1984) |
"A 76-year-old woman with acute myelogenous leukemia with approximately 65% myeloblasts on bone marrow examination was treated daily with a combination of 4 megaU of leukocyte interferon IM and 1,000 mg cimetidine PO." | 3.67 | Complete remission in a patient with acute myelogenous leukemia treated with leukocyte alpha-interferon and cimetidine. ( Ankerst, J; Fäldt, R; Flodgren, P; Nilsson, PG; Sjögren, HO, 1984) |
" Successful treatment required aggressive surgical debridement, three times daily voriconazole dosing and cimetidine CYP2C19 inhibition." | 1.40 | Disseminated Scedosporium prolificans infection in an 'extensive metaboliser': navigating the minefield of drug interactions and pharmacogenomics. ( Paratz, E; Slavin, MA; Teh, BW; Thursky, KA; Todaro, M; Trubiano, JA; Wolf, M, 2014) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (40.00) | 18.7374 |
1990's | 2 (40.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Trubiano, JA | 1 |
Paratz, E | 1 |
Wolf, M | 1 |
Teh, BW | 1 |
Todaro, M | 1 |
Thursky, KA | 1 |
Slavin, MA | 1 |
Sawutz, DG | 1 |
Kalinyak, K | 1 |
Whitsett, JA | 1 |
Johnson, CL | 1 |
Ankerst, J | 1 |
Fäldt, R | 1 |
Nilsson, PG | 1 |
Flodgren, P | 1 |
Sjögren, HO | 1 |
Mehta, J | 1 |
Powles, RL | 1 |
Treleaven, J | 1 |
Shields, M | 1 |
Agrawal, S | 1 |
Rege, K | 1 |
Mitchell, P | 1 |
Allard, S | 1 |
Weiss, RB | 1 |
Donehower, RC | 1 |
Wiernik, PH | 1 |
Ohnuma, T | 1 |
Gralla, RJ | 1 |
Trump, DL | 1 |
Baker, JR | 1 |
Van Echo, DA | 1 |
Von Hoff, DD | 1 |
Leyland-Jones, B | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Feasibility of a Randomized Controlled Clinical Trial Comparing the Use of Cetirizine to Replace Diphenhydramine in the Prevention of Reactions Related to Paclitaxel[NCT04237090] | Phase 3 | 27 participants (Actual) | Interventional | 2020-02-14 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
5 other studies available for cimetidine and Acute Myelogenous Leukemia
Article | Year |
---|---|
Disseminated Scedosporium prolificans infection in an 'extensive metaboliser': navigating the minefield of drug interactions and pharmacogenomics.
Topics: Aged; Antifungal Agents; Cimetidine; Cytochrome P-450 CYP2C19; Debridement; Drug Interactions; Human | 2014 |
Histamine H2 receptor desensitization in HL-60 human promyelocytic leukemia cells.
Topics: 1-Methyl-3-isobutylxanthine; Cell Differentiation; Cell Line; Cimetidine; Cyclic AMP; Dimaprit; Dino | 1984 |
Complete remission in a patient with acute myelogenous leukemia treated with leukocyte alpha-interferon and cimetidine.
Topics: Aged; Bone Marrow; Cimetidine; Evaluation Studies as Topic; Female; Humans; Interferon Type I; Leuke | 1984 |
Cimetidine-induced myelosuppression after bone marrow transplantation.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Cimetidine; Female; Hematopoiesis; Humans; Leukemia- | 1994 |
Hypersensitivity reactions from taxol.
Topics: Adult; Aged; Alkaloids; Antineoplastic Agents, Phytogenic; Cimetidine; Colonic Neoplasms; Dexamethas | 1990 |