cimetidine has been researched along with Acute Liver Injury, Drug-Induced in 70 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Toxic hepatitis developed but in one out of 127 peptic ulcer patients treated with cimetidine." | 7.68 | [The effect of cimetidine and gastrozepin on liver function and the pharmacotherapy of "hepatogenous" gastroduodenal ulcers and erosions]. ( Bessonova, GA; Geller, LI; Griaznova, MV, 1991) |
| "The value of cimetidine in treatment of duodenal ulcer and the Zollinger-Ellison syndrome appears to be well established." | 4.76 | A consideration of the adverse effects of cimetidine. ( McGuigan, JE, 1981) |
| " Amatoxin, a peptide contained in several mushroom species, accounts for the majority of severe mushroom poisonings by binding to RNA polymerase II irreversibly, leading to severe hepatonecrosis." | 3.74 | Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model. ( Betten, DP; Clark, RF; Favata, M; Hernandez, M; Richardson, WH; Riffenburgh, RH; Tanen, DA; Tong, TC, 2007) |
| "A 51-year-old obese woman with a duodenal ulcer developed symptomatic, famotidine-induced hepatitis." | 3.69 | Hepatitis following treatments with famotidine and then cimetidine. ( Davis, RL; Egli, D; Hashimoto, F, 1994) |
| "A 41-year-old man with rheumatoid arthritis developed severe acute hepatitis 3 days after starting cimetidine for duodenal ulcer." | 3.68 | [Cimetidine hepatitis]. ( Cohen, N; Golik, A; Zaidenstein, R, 1992) |
| "Toxic hepatitis developed but in one out of 127 peptic ulcer patients treated with cimetidine." | 3.68 | [The effect of cimetidine and gastrozepin on liver function and the pharmacotherapy of "hepatogenous" gastroduodenal ulcers and erosions]. ( Bessonova, GA; Geller, LI; Griaznova, MV, 1991) |
| "A 62-year-old man developed asymptomatic anicteric hepatitis during cimetidine therapy for duodenal ulcer disease." | 3.67 | Cimetidine hepatitis. ( Graham, DY; Gyorkey, F; Schwartz, JT, 1986) |
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| "The aim of the present work was to clarify the involvement of free radicals, cytochrome P450 toxic metabolites, and deregulation of calcium homeostasis in the mechanism of diethyldithiocarbamate (DDC) hepatotoxicity." | 1.37 | The protective effects of ascorbic acid, cimetidine, and nifedipine on diethyldithiocarbamate-induced hepatic toxicity in albino rats. ( Badawy, MM; Gaafa, KM; Hamza, AA, 2011) |
| " An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | 1.36 | Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) |
| " Furthermore, the use of antidotes that reduced the toxic insult was also recorded using this technique." | 1.35 | Acute liver acetaminophen toxicity in rabbits and the use of antidotes: a metabonomic approach in serum. ( Galanopoulou, P; Giannioti, K; Liapi, C; Mikros, E; Papalois, A; Theocharis, S; Zira, A, 2009) |
| "Cimetidine was the individual anti-ulcer drug with the highest risk of developing symptomatic acute liver disease." | 1.30 | The risk of acute liver injury associated with cimetidine and other acid-suppressing anti-ulcer drugs. ( García Rodríguez, LA; Stricker, BH; Wallander, MA, 1997) |
| "Dimethylacetamide (DMAc) is a skin-penetrating solvent able to induce hepatic damage after chronic exposure." | 1.29 | Toxicokinetics of dimethylacetamide (DMAc) in rat isolated perfused liver. ( Borm, PJ; Evelo, CT; Henderson, PT; Palmen, NG, 1993) |
| "Cimetidine pretreatment also significantly reduced the rate of hepatic glutathione depletion." | 1.27 | Selective inhibition of acetaminophen oxidation and toxicity by cimetidine and other histamine H2-receptor antagonists in vivo and in vitro in the rat and in man. ( Mitchell, MC; Schenker, S; Speeg, KV, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (54.29) | 18.7374 |
| 1990's | 14 (20.00) | 18.2507 |
| 2000's | 6 (8.57) | 29.6817 |
| 2010's | 12 (17.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Greene, N | 1 |
| Fisk, L | 1 |
| Naven, RT | 1 |
| Note, RR | 1 |
| Patel, ML | 1 |
| Pelletier, DJ | 1 |
| Morgan, RE | 2 |
| Trauner, M | 1 |
| van Staden, CJ | 2 |
| Lee, PH | 1 |
| Ramachandran, B | 1 |
| Eschenberg, M | 1 |
| Afshari, CA | 2 |
| Qualls, CW | 1 |
| Lightfoot-Dunn, R | 1 |
| Hamadeh, HK | 2 |
| Ekins, S | 1 |
| Williams, AJ | 1 |
| Xu, JJ | 1 |
| Chen, M | 2 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 2 |
| Fang, H | 2 |
| Tong, W | 3 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Warner, DJ | 1 |
| Chen, H | 1 |
| Cantin, LD | 1 |
| Kenna, JG | 2 |
| Stahl, S | 1 |
| Walker, CL | 1 |
| Noeske, T | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Salhanick, SD | 1 |
| Wax, PM | 1 |
| Schneider, SM | 1 |
| Tan, HH | 1 |
| Chang, CY | 1 |
| Martin, P | 1 |
| Zira, A | 1 |
| Mikros, E | 1 |
| Giannioti, K | 1 |
| Galanopoulou, P | 1 |
| Papalois, A | 1 |
| Liapi, C | 1 |
| Theocharis, S | 1 |
| Ishihara, Y | 1 |
| Ishii, S | 1 |
| Sakai, Y | 1 |
| Yamamura, N | 1 |
| Onishi, Y | 1 |
| Shimamoto, N | 1 |
| Gaafa, KM | 1 |
| Badawy, MM | 1 |
| Hamza, AA | 1 |
| Tong, TC | 1 |
| Hernandez, M | 1 |
| Richardson, WH | 1 |
| Betten, DP | 1 |
| Favata, M | 1 |
| Riffenburgh, RH | 1 |
| Clark, RF | 1 |
| Tanen, DA | 1 |
| Kosmidis, PA | 1 |
| Kalofonos, HP | 1 |
| Christodoulou, C | 1 |
| Syrigos, K | 1 |
| Makatsoris, T | 1 |
| Skarlos, D | 1 |
| Bakogiannis, C | 1 |
| Nicolaides, C | 1 |
| Bafaloukos, D | 1 |
| Bamias, A | 1 |
| Samantas, E | 1 |
| Xiros, N | 1 |
| Boukovinas, I | 1 |
| Fountzilas, G | 1 |
| Dimopoulos, MA | 1 |
| Tayal, V | 1 |
| Kalra, BS | 1 |
| Agarwal, S | 1 |
| Khurana, N | 1 |
| Gupta, U | 1 |
| Kolts, BE | 1 |
| Langfitt, M | 1 |
| Ivey, KJ | 1 |
| Mitchell, MC | 2 |
| Schenker, S | 2 |
| Speeg, KV | 2 |
| Leonard, TB | 1 |
| Dent, JG | 1 |
| Mariani, L | 1 |
| Minora, T | 1 |
| Souza Lima, MA | 2 |
| Black, M | 1 |
| Scott, WE | 1 |
| Kanter, R | 1 |
| Nagasue, N | 1 |
| Yukaya, H | 1 |
| Ogawa, Y | 1 |
| Sasaki, Y | 1 |
| Hirose, S | 1 |
| Freston, JW | 1 |
| Mogadam, M | 1 |
| Peterson, FJ | 1 |
| Knodell, RG | 1 |
| Lindemann, NJ | 1 |
| Steele, NM | 1 |
| McGuigan, JE | 1 |
| Soulé, JC | 1 |
| Delchier, JC | 1 |
| Morin, T | 1 |
| Bader, JP | 1 |
| Ruffalo, RL | 1 |
| Thompson, JF | 1 |
| Glade, G | 1 |
| Saccar, CL | 1 |
| Pereira, GR | 1 |
| Lorenzini, I | 1 |
| Jezequel, AM | 1 |
| Orlandi, F | 1 |
| Avant, GR | 1 |
| Jackson, JE | 1 |
| Ruiz Del Arbol, L | 1 |
| Moreira, V | 1 |
| Moreno, A | 1 |
| Hernández Ranz, F | 1 |
| Cano, A | 1 |
| García Plaza, A | 1 |
| Chmel, H | 1 |
| Idali, B | 1 |
| Miguil, M | 1 |
| Moutawakkil, S | 1 |
| Bouaggad, A | 1 |
| Guartit, A | 1 |
| Abassi, O | 1 |
| Ben Aguida, M | 1 |
| Palmen, NG | 1 |
| Evelo, CT | 1 |
| Borm, PJ | 1 |
| Henderson, PT | 1 |
| Hashimoto, F | 1 |
| Davis, RL | 1 |
| Egli, D | 1 |
| Irita, K | 1 |
| Sakai, H | 1 |
| Yamakawa, M | 1 |
| Nawata, H | 1 |
| Yoshitake, J | 1 |
| Takahashi, S | 1 |
| García Rodríguez, LA | 1 |
| Wallander, MA | 1 |
| Stricker, BH | 1 |
| Kaufenberg, AJ | 1 |
| Shepherd, MF | 1 |
| Villeneuve, JP | 1 |
| Warner, HA | 1 |
| Berthelot, P | 1 |
| Zaidenstein, R | 1 |
| Cohen, N | 1 |
| Golik, A | 1 |
| Polunina, TE | 2 |
| Fomichev, VI | 1 |
| Vasil'ev, AP | 1 |
| Lewis, RK | 1 |
| Paloucek, FP | 1 |
| Geller, LI | 1 |
| Bessonova, GA | 1 |
| Griaznova, MV | 1 |
| Marcus, DL | 1 |
| Nadel, H | 1 |
| Lew, G | 1 |
| Freedman, ML | 1 |
| Brown, BR | 1 |
| Chevalier, X | 1 |
| Awada, H | 1 |
| Baetz, A | 1 |
| Amor, B | 1 |
| Boyd, PT | 1 |
| Lepre, F | 1 |
| Dickey, JD | 1 |
| Landriault, H | 1 |
| Sirois, G | 1 |
| Chakrabarti, S | 1 |
| Cote, MG | 1 |
| Dixon, PA | 1 |
| Udeagha, AU | 1 |
| Zimmerman, HJ | 2 |
| Jacob, L | 2 |
| Bassan, H | 2 |
| Gillespie, J | 2 |
| Lukacs, L | 2 |
| Abernathy, CO | 1 |
| Lewis, JH | 1 |
| Ivlev, AS | 1 |
| Davis, M | 1 |
| Satoh, H | 1 |
| Gillette, JR | 1 |
| Takemura, T | 1 |
| Ferrans, VJ | 1 |
| Jelenich, SE | 1 |
| Neuberger, J | 1 |
| Pohl, LR | 1 |
| Vázquez Arnedo, M | 1 |
| Pastor Fanco, A | 1 |
| Bestue Fuster, JM | 1 |
| Duddy, SK | 1 |
| Hsia, MT | 1 |
| Dobbs, JH | 1 |
| Muir, JG | 1 |
| Smith, RN | 1 |
| Murase, T | 1 |
| Hazama, H | 1 |
| Okuno, H | 1 |
| Shiozaki, Y | 1 |
| Sameshima, Y | 1 |
| Schwartz, JT | 1 |
| Gyorkey, F | 1 |
| Graham, DY | 1 |
| Van Steenbergen, W | 1 |
| Vanstapel, MJ | 1 |
| Desmet, V | 1 |
| Van Kerckvoorde, L | 1 |
| De Keyzer, R | 1 |
| Brijs, R | 1 |
| Fevery, J | 1 |
| De Groote, J | 1 |
| Gugler, R | 1 |
8 reviews available for cimetidine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
H2-receptor antagonists.
Topics: Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Cimetidine; Gastric Mucosa; G | 1980 |
Cimetidine: II. Adverse reactions and patterns of use.
Topics: Cardiovascular Diseases; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Ci | 1982 |
A consideration of the adverse effects of cimetidine.
Topics: Agranulocytosis; Animals; Bone Marrow; Central Nervous System; Chemical and Drug Induced Liver Injur | 1981 |
[Maintenance cimetidine treatment in duodenal ulcer disease. Second part: Side-effects and indications (author's transl)].
Topics: Animals; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Cimetidine; Confusion; Dogs; | 1980 |
Assessment and treatment of acetaminophen overdose.
Topics: Acetaminophen; Acetylcysteine; Animals; Chemical and Drug Induced Liver Injury; Cimetidine; Drug Ove | 1991 |
Hepatic effects of drugs used in the treatment of peptic ulcer disease.
Topics: Aged; Chemical and Drug Induced Liver Injury; Cimetidine; Drug Interactions; Female; Histamine H2 An | 1987 |
Protective agents for acetaminophen overdose.
Topics: Acetaminophen; Acetylcysteine; Animals; Cell Membrane; Chemical and Drug Induced Liver Injury; Cimet | 1986 |
2 trials available for cimetidine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Paclitaxel and gemcitabine versus carboplatin and gemcitabine in patients with advanced non-small-cell lung cancer. A phase III study of the Hellenic Cooperative Oncology Group.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcino | 2008 |
Prophylaxis of upper gastrointestinal bleeding with cimetidine in patients undergoing partial hepatectomy.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Cimetidine; Female; Hepatectomy; Humans; Liver | 1984 |
60 other studies available for cimetidine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
In response to Tong TC, et al. Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model.
Topics: Alpha-Amanitin; Amanitins; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Cimetidine; H | 2008 |
Acetaminophen hepatotoxicity: current management.
Topics: Acetaminophen; Acetylcysteine; Antidotes; Charcoal; Chemical and Drug Induced Liver Injury; Cimetidi | 2009 |
Acute liver acetaminophen toxicity in rabbits and the use of antidotes: a metabonomic approach in serum.
Topics: Acetaminophen; Acetylcysteine; Acute Disease; Alanine Transaminase; Animals; Antidotes; Aspartate Am | 2009 |
Crucial role of cytochrome P450 in hepatotoxicity induced by 2,3-dimethoxy-1,4-naphthoquinone in rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cimetidine; Cytochr | 2011 |
The protective effects of ascorbic acid, cimetidine, and nifedipine on diethyldithiocarbamate-induced hepatic toxicity in albino rats.
Topics: Animals; Ascorbic Acid; Biomarkers; Calcium; Chemical and Drug Induced Liver Injury; Cimetidine; Cyt | 2011 |
Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model.
Topics: Acetylcysteine; Alanine Transaminase; Amanitins; Animals; Antidotes; Aspartate Aminotransferases; Ch | 2007 |
Hepatoprotective effect of tocopherol against isoniazid and rifampicin induced hepatotoxicity in albino rabbits.
Topics: Animals; Antioxidants; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Cimetidine; Do | 2007 |
Drugs and the liver.
Topics: Acetaminophen; Adult; Aspirin; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liv | 1984 |
Selective inhibition of acetaminophen oxidation and toxicity by cimetidine and other histamine H2-receptor antagonists in vivo and in vitro in the rat and in man.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cimetidine; Glucuronates; Glutathion | 1984 |
Effects of H2 receptor antagonists on the hepatotoxicity of various chemicals.
Topics: 1-Propanol; Acetaminophen; Animals; Bromobenzenes; Carbon Tetrachloride Poisoning; Chemical and Drug | 1984 |
[Drug surveillance. Monitoring the collateral effects of drugs in the post-marketing phase: cimetidine. I].
Topics: Chemical and Drug Induced Liver Injury; Cimetidine; Endocrine System Diseases; Evaluation Studies as | 1984 |
Hepatitis associated with ranitidine.
Topics: Aged; Chemical and Drug Induced Liver Injury; Cimetidine; Female; Humans; Leukocyte Count; Liver Fun | 1984 |
Possible ranitidine hepatotoxicity.
Topics: Adult; Chemical and Drug Induced Liver Injury; Cholangitis; Cimetidine; Diagnosis, Differential; Fem | 1984 |
The GI drug column. The ACG committee on FDA related matters.
Topics: Alginates; Aluminum Hydroxide; Antacids; Bicarbonates; Chemical and Drug Induced Liver Injury; Cheno | 1983 |
Prevention of acetaminophen and cocaine hepatotoxicity in mice by cimetidine treatment.
Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cimetidine; Co | 1983 |
Cimetidine and acetylcysteine as antidote for acetaminophen overdose.
Topics: Acetaminophen; Acetylcysteine; Antidotes; Chemical and Drug Induced Liver Injury; Cimetidine; Cytoch | 1982 |
Cimetidine in pregnancy: apparent transient liver impairment in the newborn.
Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cimetidine; Fema | 1980 |
Cimetidine-induced hepatitis. Electron microscopic observations and clinical pattern of liver injury.
Topics: Adult; Chemical and Drug Induced Liver Injury; Cimetidine; Drug Hypersensitivity; Guanidines; Humans | 1981 |
Cimetidine protects against acetaminophen hepatotoxicity in rats.
Topics: Acetaminophen; Alanine Transaminase; Aminopyrine; Animals; Aspartate Aminotransferases; Chemical and | 1981 |
Cimetidine protects against acetaminophen hepatoxicity.
Topics: Acetaminophen; Adolescent; Animals; Chemical and Drug Induced Liver Injury; Cimetidine; Female; Guan | 1981 |
Bridging hepatic necrosis associated with cimetidine.
Topics: Aged; Chemical and Drug Induced Liver Injury; Cimetidine; Esophagitis, Peptic; Guanidines; Humans; L | 1980 |
Fatal acute hepatic necrosis due to fluconazole.
Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Cimetidine; Fatal Outcome; Fluconazole; Human | 1995 |
[Acute phostoxin poisoning].
Topics: Acute Disease; Adult; Aluminum Compounds; Cardiotonic Agents; Chemical and Drug Induced Liver Injury | 1995 |
Toxicokinetics of dimethylacetamide (DMAc) in rat isolated perfused liver.
Topics: Acetamides; Animals; Bile; Chemical and Drug Induced Liver Injury; Cimetidine; Cryoprotective Agents | 1993 |
Hepatitis following treatments with famotidine and then cimetidine.
Topics: Chemical and Drug Induced Liver Injury; Cimetidine; Duodenal Ulcer; Famotidine; Fatty Liver; Female; | 1994 |
Effects of OP 2507, a stable analogue of prostaglandin I2, on carbon tetrachloride-induced liver damage in starved rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Carbon Tetrachloride Poisoning; Chemical and Drug Induc | 1996 |
The risk of acute liver injury associated with cimetidine and other acid-suppressing anti-ulcer drugs.
Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Anti-Ulcer Agents; Case-Control Studies; Ch | 1997 |
Role of cimetidine in the treatment of acetaminophen poisoning.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cimetidine; Drug Overdose; Humans; L | 1998 |
Cimetidine hepatitis.
Topics: Aged; Chemical and Drug Induced Liver Injury; Cimetidine; Drug Hypersensitivity; Esophagitis, Peptic | 1979 |
Cimetidine hepatitis.
Topics: Chemical and Drug Induced Liver Injury; Cimetidine; Guanidines; Humans | 1979 |
[Cimetidine hepatitis].
Topics: Acute Disease; Adult; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cimetidine; Duo | 1992 |
[Acute drug-induced hepatitis in a patient with peptic ulcer].
Topics: Aged; Cephalothin; Chemical and Drug Induced Liver Injury; Cimetidine; Duodenal Ulcer; Humans; Male; | 1992 |
[The effect of cimetidine and gastrozepin on liver function and the pharmacotherapy of "hepatogenous" gastroduodenal ulcers and erosions].
Topics: Adult; Anti-Ulcer Agents; Chemical and Drug Induced Liver Injury; Cimetidine; Drug Evaluation; Drug | 1991 |
Cimetidine suppresses chemically induced experimental hepatic porphyria.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Chemical and Drug Induced Liver Inju | 1990 |
Cimetidine pretreatment and halothane hepatotoxicity.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cimetidine; Halothane; Humans; Premedication | 1990 |
Danazol induced pancreatitis and hepatitis.
Topics: Acetaminophen; Adult; Chemical and Drug Induced Liver Injury; Cimetidine; Danazol; Female; Humans; L | 1990 |
Chronic active hepatitis associated with cimetidine.
Topics: Adult; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Cime | 1989 |
Effect of cimetidine on hepatic biochemical changes, liver toxicity and major urinary metabolite excretion of trichloroethylene in rats.
Topics: Alanine Transaminase; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cimetidine | 1989 |
The effect of some hepatotoxins on the sulphoxidation of cimetidine in rat.
Topics: 1-Propanol; Animals; Bromobenzenes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver | 1986 |
Effects of H2-blocking agents on hepatocytes in vitro: correlation with potential for causing hepatic disease in patients.
Topics: Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cimetidine; Histamine | 1986 |
[Severe acute drug-induced hepatitis in a patient with benign hyperbilirubinemia of the Gilbert type].
Topics: Adult; Chemical and Drug Induced Liver Injury; Cimetidine; Gastroenteritis; Gilbert Disease; Humans; | 1988 |
Investigation of the immunological basis of halothane-induced hepatotoxicity.
Topics: Animals; Antigen-Antibody Complex; Cell Membrane; Chemical and Drug Induced Liver Injury; Cimetidine | 1986 |
[Cimetidine and toxic hepatitis].
Topics: Adult; Chemical and Drug Induced Liver Injury; Cimetidine; Duodenal Ulcer; Humans; Male | 1987 |
Cytoprotective effects of modulators of oxidative xenobiotic metabolism in precocene II-induced hepatotoxicity.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzopyrans; Cell Survival; Chemical and | 1987 |
Ranitidine and hepatic injury.
Topics: Chemical and Drug Induced Liver Injury; Cimetidine; Humans; Ranitidine; Retrospective Studies | 1986 |
H2-antagonists and hepatitis.
Topics: Chemical and Drug Induced Liver Injury; Cimetidine; Humans; Ranitidine | 1986 |
Effect of H2-receptor antagonists on acetaminophen-induced hepatic injury.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cimetidine; Famotidine; Glutathione; | 1986 |
Effects of three H2 antagonists on the isolated perfused rat liver. Correlation of bile flow changes with potential for causing hepatic disease in patients.
Topics: Animals; Bile; Chemical and Drug Induced Liver Injury; Cimetidine; Imidazoles; In Vitro Techniques; | 1986 |
Cimetidine hepatitis.
Topics: Chemical and Drug Induced Liver Injury; Cimetidine; Duodenal Ulcer; Humans; Male; Microscopy, Electr | 1986 |
Cimetidine-induced liver injury. Report of three cases.
Topics: Aged; Chemical and Drug Induced Liver Injury; Cimetidine; Gastritis; Gastritis, Hypertrophic; Humans | 1985 |
[Hepatic drug interactions].
Topics: Chemical and Drug Induced Liver Injury; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Drug Interac | 1985 |