cimetidine has been researched along with Acute Kidney Failure in 36 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine is a histamine H2-receptor antagonist." | 6.38 | [A case of acute interstitial nephritis and nonoliguria acute renal failure induced by cimetidine]. ( Koarada, S; Nagano, Y; Sakemi, T; Syouno, Y; Watanabe, T, 1992) |
| "Cimetidine treatment significantly decreased creatinine, BUN, K, Na, SBP and creatine kinase and increased GFR and urine volume compared to group II." | 5.42 | A study on the effect of cimetidine and L-carnitine on myoglobinuric acute kidney injury in male rats. ( Eissa, H; Elattar, S; Estaphan, S; Farouk, M; Rashed, L, 2015) |
| "In the postoperative patient with acute renal failure, the management of the metabolic alkalosis is particularly difficult, and established modalities of therapy are sometimes ineffective and can be hazardous to the patient." | 5.26 | Cimetidine in the management of metabolic alkalosis induced by nasogastric drainage. ( Barton, CH; Mirahmadi, KS; Ness, RL; Saiki, JK; Vaziri, ND, 1979) |
| "A significantly higher incidence of acute renal failure was noted in the antacid-treated group when compared with the cimetidine and sucralfate groups." | 2.66 | Prophylaxis of upper gastrointestinal tract bleeding in mechanically ventilated patients. A randomized study comparing the efficacy of sucralfate, cimetidine, and antacids. ( Cannon, LA; Gardner, W; Heiselman, D; Jones, J, 1987) |
| "Cimetidine is a histamine H2-receptor antagonist." | 2.38 | [A case of acute interstitial nephritis and nonoliguria acute renal failure induced by cimetidine]. ( Koarada, S; Nagano, Y; Sakemi, T; Syouno, Y; Watanabe, T, 1992) |
| "For medical treatment of acute pancreatitis, only very few effective measures can be recommended." | 2.36 | [Medical treatment of acute pancreatitis (author's transl)]. ( Neumayr, A, 1980) |
| "Cimetidine treatment significantly decreased creatinine, BUN, K, Na, SBP and creatine kinase and increased GFR and urine volume compared to group II." | 1.42 | A study on the effect of cimetidine and L-carnitine on myoglobinuric acute kidney injury in male rats. ( Eissa, H; Elattar, S; Estaphan, S; Farouk, M; Rashed, L, 2015) |
| " The aim of this study was to assess whether appropriate dosage adjustments were made in hospitalized patients with renal impairment." | 1.42 | Drug dosage adjustment in hospitalized patients with renal impairment at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia. ( Getachew, H; Shibeshi, W; Tadesse, Y, 2015) |
| "Cimetidine was intravenously infused to ureter ligated (UL) and control rats, and cimetidine concentration in plasma, brain and cerebrospinal fluid (CSF) were compared." | 1.29 | Effect of acute renal failure on neurotoxicity of cimetidine in rats. ( Iga, T; Kawakami, J; Nakada, Y; Sawada, Y; Yamamoto, K, 1995) |
| "Because acute renal failure is included in the definition of sequential organ failure, we attempted to determine whether cimetidine could significantly reduce gastrointestinal bleeding in our series of patients who had acute renal failure after resection of dissecting abdominal aneurysms." | 1.26 | Clinical use of cimetidine in acute renal failure after resection of abdominal aneurysms. ( Vaz, AJ, 1980) |
| "In the postoperative patient with acute renal failure, the management of the metabolic alkalosis is particularly difficult, and established modalities of therapy are sometimes ineffective and can be hazardous to the patient." | 1.26 | Cimetidine in the management of metabolic alkalosis induced by nasogastric drainage. ( Barton, CH; Mirahmadi, KS; Ness, RL; Saiki, JK; Vaziri, ND, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (63.89) | 18.7374 |
| 1990's | 8 (22.22) | 18.2507 |
| 2000's | 2 (5.56) | 29.6817 |
| 2010's | 2 (5.56) | 24.3611 |
| 2020's | 1 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Nieskens, TTG | 1 |
| Persson, M | 1 |
| Kelly, EJ | 1 |
| Sjögren, AK | 1 |
| Estaphan, S | 1 |
| Eissa, H | 1 |
| Elattar, S | 1 |
| Rashed, L | 1 |
| Farouk, M | 1 |
| Getachew, H | 1 |
| Tadesse, Y | 1 |
| Shibeshi, W | 1 |
| Pabla, N | 1 |
| Murphy, RF | 1 |
| Liu, K | 1 |
| Dong, Z | 1 |
| Nogi, K | 1 |
| Taniguchi, H | 1 |
| Onoda, Y | 1 |
| Bories, P | 1 |
| Michel, H | 1 |
| Duclos, B | 1 |
| Beraud, JJ | 1 |
| Mirouze, J | 1 |
| Neumayr, A | 1 |
| Lankisch, PG | 1 |
| Ellis, D | 1 |
| Gartner, JC | 1 |
| Galvis, AG | 1 |
| Payne, CR | 1 |
| Ackrill, P | 1 |
| Ralston, AJ | 1 |
| Santoro, JJ | 1 |
| Pitone, JM | 1 |
| Biondi, RJ | 1 |
| Chiesa, JC | 1 |
| Pecora, AA | 1 |
| Rowley-Jones, D | 1 |
| Flind, AC | 1 |
| Reddy, J | 1 |
| Vaz, AJ | 1 |
| Norlander, B | 1 |
| Bodemar, G | 1 |
| Larsson, R | 1 |
| Walan, A | 1 |
| Rudnick, MR | 1 |
| Bastl, CP | 1 |
| Elfenbein, IB | 1 |
| Sirota, RA | 1 |
| Yudis, M | 1 |
| Narins, RG | 1 |
| Stricker, BH | 1 |
| Reith, CB | 1 |
| Teruel, JL | 1 |
| Garcia-Cosmes, P | 1 |
| Marcen, R | 1 |
| Ortuno, J | 1 |
| Richman, AV | 1 |
| Narayan, JL | 1 |
| Hirschfield, JS | 1 |
| Seidelin, R | 1 |
| Nakada, Y | 1 |
| Yamamoto, K | 1 |
| Kawakami, J | 1 |
| Sawada, Y | 1 |
| Iga, T | 1 |
| Baliga, R | 1 |
| Zhang, Z | 1 |
| Baliga, M | 1 |
| Shah, SV | 1 |
| Somers, M | 1 |
| Piqueras, AI | 1 |
| Strange, K | 1 |
| Zeidel, ML | 1 |
| Pfaller, W | 1 |
| Gawryl, M | 1 |
| Harris, HW | 1 |
| Barton, CH | 1 |
| Vaziri, ND | 1 |
| Ness, RL | 1 |
| Saiki, JK | 1 |
| Mirahmadi, KS | 1 |
| Martin, LF | 1 |
| Staloch, DK | 1 |
| Simonowitz, DA | 1 |
| Dellinger, EP | 1 |
| Max, MH | 1 |
| Grave, W | 1 |
| Nadorp, JN | 1 |
| Rutten, JJ | 1 |
| Koarada, S | 1 |
| Nagano, Y | 1 |
| Sakemi, T | 1 |
| Syouno, Y | 1 |
| Watanabe, T | 1 |
| Maiza, A | 2 |
| Daley-Yates, PT | 2 |
| Maeba, T | 1 |
| Kondo, S | 1 |
| Maeda, A | 1 |
| Ishida, M | 1 |
| Ishigami, M | 1 |
| Maeda, T | 1 |
| Sezai, Y | 1 |
| Miyake, H | 1 |
| Eguchi, M | 1 |
| Yabuki, S | 1 |
| Namba, S | 1 |
| Cannon, LA | 1 |
| Heiselman, D | 1 |
| Gardner, W | 1 |
| Jones, J | 1 |
| Christensen, LA | 1 |
| Schmidt, EB | 1 |
| Ma, KW | 1 |
| Mader, R | 1 |
| Schonfeld, S | 1 |
2 reviews available for cimetidine and Acute Kidney Failure
| Article | Year |
|---|---|
[Medical treatment of acute pancreatitis (author's transl)].
Topics: Acute Disease; Acute Kidney Injury; Analgesics; Anti-Bacterial Agents; Aprotinin; Calcitonin; Cimeti | 1980 |
[A case of acute interstitial nephritis and nonoliguria acute renal failure induced by cimetidine].
Topics: Acute Kidney Injury; Cimetidine; Female; Humans; Kidney; Middle Aged; Nephritis, Interstitial | 1992 |
1 trial available for cimetidine and Acute Kidney Failure
| Article | Year |
|---|---|
Prophylaxis of upper gastrointestinal tract bleeding in mechanically ventilated patients. A randomized study comparing the efficacy of sucralfate, cimetidine, and antacids.
Topics: Acute Kidney Injury; Antacids; Cimetidine; Costs and Cost Analysis; Female; Gastrointestinal Hemorrh | 1987 |
33 other studies available for cimetidine and Acute Kidney Failure
| Article | Year |
|---|---|
A Multicompartment Human Kidney Proximal Tubule-on-a-Chip Replicates Cell Polarization-Dependent Cisplatin Toxicity.
Topics: Acute Kidney Injury; Cell Culture Techniques; Cells, Cultured; Cimetidine; Cisplatin; Drug Evaluatio | 2020 |
A study on the effect of cimetidine and L-carnitine on myoglobinuric acute kidney injury in male rats.
Topics: Acute Kidney Injury; Animals; Carnitine; Cimetidine; Creatine Kinase; Creatinine; Disease Models, An | 2015 |
Drug dosage adjustment in hospitalized patients with renal impairment at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Arrhythmia Agents | 2015 |
The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Apoptosis; Cation Transport Proteins; Cell Line | 2009 |
Effects of the anti-ulcer agents ecabet sodium, cimetidine and sucralfate on acetylsalicylic acid-induced gastric mucosal damage deteriorated by renal failure in rats.
Topics: Abietanes; Acute Kidney Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; | 2002 |
Use of ranitidine, without mental confusion, in patients with renal failure.
Topics: Acute Kidney Injury; Aged; Cimetidine; Cognition Disorders; Confusion; Duodenal Ulcer; Furans; Hista | 1980 |
[Conservative treatment of acute pancreatitis].
Topics: Acetazolamide; Acute Disease; Acute Kidney Injury; Aftercare; Antacids; Aprotinin; Atropine; Bacteri | 1982 |
Acute renal failure in infants and children: diagnosis, complications, and treatment.
Topics: Acidosis; Acute Kidney Injury; Age Factors; Amino Acids, Essential; Anti-Bacterial Agents; Burns; Ch | 1981 |
Acute renal failure and rise in alkaline phosphatase activity caused by cimetidine.
Topics: Acute Kidney Injury; Aged; Alkaline Phosphatase; Cimetidine; Guanidines; Humans; Male | 1982 |
Cimetidine-induced acute renal failure.
Topics: Acute Kidney Injury; Aged; Cimetidine; Female; Guanidines; Humans; Nephritis, Interstitial | 1982 |
Cimetidine-induced renal failure.
Topics: Acute Kidney Injury; Cimetidine; Guanidines; Humans | 1982 |
Hyperglycaemia and renal failure related to the use of cimetidine.
Topics: Acute Kidney Injury; Aged; Cimetidine; Female; Guanidines; Humans; Hyperglycemia; Male; Middle Aged | 1981 |
Clinical use of cimetidine in acute renal failure after resection of abdominal aneurysms.
Topics: Acute Kidney Injury; Aged; Aorta, Abdominal; Aortic Aneurysm; Aortic Dissection; Cimetidine; Gastroi | 1980 |
Therapeutic plasma concentrations of cimetidine in normal renal function and dosage requirements in renal failure.
Topics: Acute Kidney Injury; Cimetidine; Creatinine; Dose-Response Relationship, Drug; Guanidines; Humans | 1980 |
Cimetidine-induced acute renal failure.
Topics: Acute Kidney Injury; Aged; Cimetidine; Guanidines; Humans; Male; Middle Aged; Nephritis, Interstitia | 1982 |
[Severe kidney function disorders during use of cimetidine (Tagamet)].
Topics: Acute Kidney Injury; Adolescent; Cimetidine; Creatinine; Guanidines; Humans; Male; Urea | 1980 |
Renal failure with cimetidine.
Topics: Acute Kidney Injury; Aged; Cimetidine; Female; Guanidines; Humans; Middle Aged | 1981 |
Acute interstitial nephritis and acute renal failure associated with cimetidine therapy.
Topics: Acute Kidney Injury; Aged; Biopsy; Cimetidine; Eosinophils; Guanidines; Humans; Kidney; Male; Nephri | 1981 |
Cimetidine and renal failure.
Topics: Acute Kidney Injury; Aged; Cimetidine; Guanidines; Humans; Male | 1980 |
Effect of acute renal failure on neurotoxicity of cimetidine in rats.
Topics: Acute Kidney Injury; Animals; Cimetidine; Dose-Response Relationship, Drug; Male; Rats; Rats, Wistar | 1995 |
Evidence for cytochrome P-450 as a source of catalytic iron in myoglobinuric acute renal failure.
Topics: Acute Kidney Injury; Animals; Anti-Ulcer Agents; Bleomycin; Blood Urea Nitrogen; Cimetidine; Creatin | 1996 |
Interactions of ultrapure bovine hemoglobin with renal epithelial cells in vivo and in vitro.
Topics: Acute Kidney Injury; Animals; Cattle; Cell Line; Cimetidine; Creatinine; Dextrans; Endocytosis; Endo | 1997 |
Cimetidine in the management of metabolic alkalosis induced by nasogastric drainage.
Topics: Acute Kidney Injury; Adult; Alkalosis; Blood; Cimetidine; Gastric Juice; Guanidines; Humans; Hydroge | 1979 |
Failure of cimetidine prophylaxis in the critically ill.
Topics: Acute Kidney Injury; Bacterial Infections; Child; Cimetidine; Female; Gastric Juice; Guanidines; Hum | 1979 |
Cimetidine and renal failure.
Topics: Acute Kidney Injury; Aged; Cimetidine; Gastritis; Guanidines; Humans; Male; Postoperative Complicati | 1977 |
Prediction of the renal clearance of cimetidine using endogenous N-1-methylnicotinamide.
Topics: Acute Kidney Injury; Animals; Cimetidine; Glomerular Filtration Rate; Kidney; Kidney Tubules, Proxim | 1991 |
[Acute renal failure associated with miscellaneous drugs].
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Cimetidine; Furosemide; Humans; Lithi | 1991 |
Estimation of the renal clearance of drugs using endogenous N-1-methylnicotinamide.
Topics: Acute Kidney Injury; Animals; Cephalexin; Cimetidine; Glomerular Filtration Rate; Inulin; Kidney; Ki | 1990 |
Do the H2-receptor antagonists, cimetidine and famotidine, modify the degree of renal recovery following renal insult?
Topics: Acute Kidney Injury; Animals; Cimetidine; Constriction; Famotidine; Gentamicins; Kidney; Male; Rats; | 1990 |
[Inhibitory effects of omeprazole and cimetidine on the formation of gastric ulcer in rats with obstructive jaundice and acute renal failure].
Topics: Acute Kidney Injury; Animals; Cholestasis; Cimetidine; Gastric Mucosa; Male; Omeprazole; Rats; Rats, | 1988 |
Perforated peptic ulcer--a complication in acute salicylate intoxication.
Topics: Acute Disease; Acute Kidney Injury; Aspirin; Cimetidine; Female; Humans; Middle Aged; Peptic Ulcer P | 1987 |
Cimetidine and the kidney.
Topics: Acute Kidney Injury; Cimetidine; Graft Rejection; Humans; Kidney Diseases; Nephritis, Interstitial | 1986 |
[Acute renal failure associated with cimetidine].
Topics: Acute Kidney Injury; Cimetidine; Humans; Male; Middle Aged | 1986 |