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cimetidine and Achlorhydria

cimetidine has been researched along with Achlorhydria in 18 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Achlorhydria: A lack of HYDROCHLORIC ACID in GASTRIC JUICE despite stimulation of gastric secretion.

Research Excerpts

ExcerptRelevanceReference
"Pneumonia, in infants suffering from esophageal atresia with lower esophageal fistula, is usually caused by gastric reflux through the fistula, In order to abolish the acidity of the gastric content, Cimetidine i."7.66Use of cimetidine in esophageal atresia with lower tracheoesophageal fistula. ( Bar-Maor, JA; Monies-Chass, I; Shoshany, G, 1981)
" Similarly we have studied the role of gastric acid deregulation in achlorhydria, the Zollinger-Ellison syndrome, and duodenal ulcer, and the influence of the antacid drugs cimetidine and ranitidine under duodenal ulcer conditions."3.67A model study of the regulation of gastric acid secretion. ( de Goede, J; Hekkens, W; Van Duijn, B; Verveen, AA; Ypey, DL, 1989)
"To investigate the possibility that an abnormality of gastric emptying exists in duodenal ulcer and to determine if such an abnormality persists after ulcer healing, scintigraphic gastric emptying measurements were undertaken in 16 duodenal ulcer patients before, during, and after therapy with cimetidine; in 12 patients with pernicious anemia, and in 12 control subjects."3.67Is gastric emptying abnormal in duodenal ulcer? ( Forrest, JA; Heading, RC; Holt, S; Taylor, TV; Tothill, P, 1986)
"Pneumonia, in infants suffering from esophageal atresia with lower esophageal fistula, is usually caused by gastric reflux through the fistula, In order to abolish the acidity of the gastric content, Cimetidine i."3.66Use of cimetidine in esophageal atresia with lower tracheoesophageal fistula. ( Bar-Maor, JA; Monies-Chass, I; Shoshany, G, 1981)
"The effect of food intake on the bioavailability of sulpiride from a commercial film-coated tablet (100 mg/T) treated with polyvinylacetal diethylaminoacetate (AEA), which remains undissolved at pH above 4 approximately 5, were investigated in four healthy male subjects in the normal state or in a drug-induced achlorhydric state."1.28Effects of food intake on the bioavailability of sulpiride from AEA film-coated tablet having a pH-dependent dissolution characteristic in normal or drug-induced achlorhydric subjects. ( Hamaguchi, T; Kobayashi, M; Mizuno, N; Shinkuma, D; Yamanaka, Y, 1991)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199016 (88.89)18.7374
1990's1 (5.56)18.2507
2000's1 (5.56)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Haggerty, T1
Shmuely, H1
Parsonnet, J1
Reed, PI2
Smith, PL1
Haines, K1
House, FR1
Walters, CL2
Cristiano, P1
Paradisi, F1
Bo-Linn, GW1
Davis, GR1
Buddrus, DJ1
Morawski, SG1
Santa Ana, C1
Fordtran, JS1
Spitz, IM1
Novis, BH1
Ebert, R1
Trestian, S1
LeRoith, D1
Creutzfeldt, W1
Steinberg, WM1
Lewis, JH1
Katz, DM1
Bar-Maor, JA1
Shoshany, G1
Monies-Chass, I1
Rominger, JM1
Chey, WY1
Chang, TM1
Taylor, TV2
Lee, D1
Howatson, AG1
Anderson, J1
MacLeod, IB1
Ruddell, WS1
Cassell, PG1
Hill, MJ1
Elder, JB1
Ganguli, PC1
Gillespie, IE1
Shinkuma, D1
Hamaguchi, T1
Kobayashi, M1
Yamanaka, Y1
Mizuno, N1
Van Duijn, B1
Ypey, DL1
de Goede, J1
Verveen, AA1
Hekkens, W1
Stockbruegger, RW1
Marshall, BJ1
Holt, S1
Heading, RC1
Forrest, JA1
Tothill, P1

Trials

2 trials available for cimetidine and Achlorhydria

ArticleYear
Helicobacter pylori in cathartic stools of subjects with and without cimetidine-induced hypochlorhydria.
    Journal of medical microbiology, 2003, Volume: 52, Issue:Pt 2

    Topics: Achlorhydria; Cathartics; Cimetidine; Feces; Follow-Up Studies; Helicobacter pylori; Histamine H2 An

2003
Bacterial overgrowth as a consequence of reduced gastric acidity.
    Scandinavian journal of gastroenterology. Supplement, 1985, Volume: 111

    Topics: Achlorhydria; Aged; Anemia, Pernicious; Bacteria; Benzodiazepinones; Cimetidine; Clinical Trials as

1985

Other Studies

16 other studies available for cimetidine and Achlorhydria

ArticleYear
Effect of cimetidine on gastric juice N-nitrosamine concentration.
    Lancet (London, England), 1981, Sep-12, Volume: 2, Issue:8246

    Topics: Achlorhydria; Adolescent; Adult; Aged; Bacteria; Cimetidine; Digestive System; Dyspepsia; Fasting; F

1981
Can cimetidine facilitate infections by oral route.
    Lancet (London, England), 1982, Jul-03, Volume: 2, Issue:8288

    Topics: Achlorhydria; Adult; Brucella; Brucellosis; Cimetidine; Duodenal Ulcer; Guanidines; Humans; Hydrogen

1982
An evaluation of the importance of gastric acid secretion in the absorption of dietary calcium.
    The Journal of clinical investigation, 1984, Volume: 73, Issue:3

    Topics: Achlorhydria; Adult; Anemia, Pernicious; Calcium Carbonate; Calcium, Dietary; Cimetidine; Citrates;

1984
Betazole-induced GIP secretion is not mediated by gastric HCl.
    Metabolism: clinical and experimental, 1982, Volume: 31, Issue:4

    Topics: Achlorhydria; Adolescent; Adult; Anemia, Pernicious; Betazole; Blood Pressure; Cimetidine; Gastric A

1982
Antacids inhibit absorption of cimetidine.
    The New England journal of medicine, 1982, Aug-12, Volume: 307, Issue:7

    Topics: Achlorhydria; Adult; Antacids; Cimetidine; Duodenal Ulcer; Eating; Fasting; Female; Guanidines; Huma

1982
Use of cimetidine in esophageal atresia with lower tracheoesophageal fistula.
    Journal of pediatric surgery, 1981, Volume: 16, Issue:1

    Topics: Achlorhydria; Child; Child, Preschool; Cimetidine; Esophageal Atresia; Female; Guanidines; Humans; I

1981
Plasma secretin concentrations and gastric pH in healthy subjects and patients with digestive diseases.
    Digestive diseases and sciences, 1981, Volume: 26, Issue:7

    Topics: Achlorhydria; Adolescent; Adult; Aged; Antacids; Celiac Disease; Cimetidine; Digestion; Duodenal Ulc

1981
Gastric cancer in patients who have taken cimetidine.
    Lancet (London, England), 1979, Jun-09, Volume: 1, Issue:8128

    Topics: Achlorhydria; Adenocarcinoma; Adult; Aged; Cimetidine; Female; Guanidines; Humans; Male; Stomach Neo

1979
Gastric cancer in patients who have taken cimetidine.
    Lancet (London, England), 1979, Jun-09, Volume: 1, Issue:8128

    Topics: Achlorhydria; Carcinogens; Cimetidine; Guanidines; Humans; Nitrosamines; Stomach Neoplasms

1979
Gastric cancer in patients who have taken cimetidine.
    Lancet (London, England), 1979, Jun-09, Volume: 1, Issue:8128

    Topics: Achlorhydria; Carcinogens; Carcinoma in Situ; Cimetidine; Gastric Juice; Guanidines; Humans; Male; M

1979
Gastric cancer in patients who have taken cimetidine.
    Lancet (London, England), 1979, Jun-09, Volume: 1, Issue:8128

    Topics: Achlorhydria; Cimetidine; Gastric Juice; Guanidines; Humans; Nitrosamines; Stomach Neoplasms

1979
Gastric cancer in patients who have taken cimetidine.
    Lancet (London, England), 1979, Aug-04, Volume: 2, Issue:8136

    Topics: Achlorhydria; Animals; Carcinogens; Cimetidine; Guanidines; Humans; In Vitro Techniques; Methylnitro

1979
Effects of food intake on the bioavailability of sulpiride from AEA film-coated tablet having a pH-dependent dissolution characteristic in normal or drug-induced achlorhydric subjects.
    International journal of clinical pharmacology, therapy, and toxicology, 1991, Volume: 29, Issue:8

    Topics: Achlorhydria; Adult; Biological Availability; Chromatography, High Pressure Liquid; Cimetidine; Food

1991
A model study of the regulation of gastric acid secretion.
    The American journal of physiology, 1989, Volume: 257, Issue:1 Pt 1

    Topics: Achlorhydria; Cimetidine; Computer Simulation; Duodenal Ulcer; Food; Gastric Acid; Gastric Emptying;

1989
Campylobacter pyloridis and gastritis.
    The Journal of infectious diseases, 1986, Volume: 153, Issue:4

    Topics: Achlorhydria; Biopsy; Bismuth; Campylobacter; Campylobacter Infections; Cimetidine; Duodenal Ulcer;

1986
Is gastric emptying abnormal in duodenal ulcer?
    Digestive diseases and sciences, 1986, Volume: 31, Issue:7

    Topics: Achlorhydria; Adult; Aged; Anemia, Pernicious; Cimetidine; Duodenal Ulcer; Female; Gastric Emptying;

1986