cimetidine has been researched along with Abnormalities, Drug-Induced in 7 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Both p-HPPH and m-HPPH were much less developmentally toxic than DPH." | 1.28 | Use of Frog Embryo Teratogenesis Assay-Xenopus and an exogenous metabolic activation system to evaluate the developmental toxicity of diphenylhydantoin. ( Bantle, JA; Fort, DJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matok, I | 1 |
| Gorodischer, R | 1 |
| Koren, G | 2 |
| Sheiner, E | 1 |
| Wiznitzer, A | 1 |
| Uziel, E | 1 |
| Levy, A | 1 |
| Witter, FR | 1 |
| King, TM | 1 |
| Blake, DA | 1 |
| Anand, S | 1 |
| Van Thiel, DH | 1 |
| Ruigómez, A | 1 |
| García Rodríguez, LA | 1 |
| Cattaruzzi, C | 1 |
| Troncon, MG | 1 |
| Agostinis, L | 1 |
| Wallander, MA | 1 |
| Johansson, S | 1 |
| Fort, DJ | 2 |
| Rayburn, JR | 1 |
| Bantle, JA | 2 |
| Zemlickis, DM | 1 |
1 review available for cimetidine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
The effects of chronic gastrointestinal medication on the fetus and neonate.
Topics: Abnormalities, Drug-Induced; Antacids; Antiemetics; Cathartics; Cimetidine; Colonic Diseases, Functi | 1981 |
6 other studies available for cimetidine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
The safety of H(2)-blockers use during pregnancy.
Topics: Abnormalities, Drug-Induced; Abortion, Therapeutic; Adolescent; Adult; Apgar Score; Cimetidine; Coho | 2010 |
Prenatal and neonatal exposure to cimetidine results in gonadal and sexual dysfunction in adult males.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Suckling; Cimetidine; Female; Guanidines; Male; Pregn | 1982 |
Use of cimetidine, omeprazole, and ranitidine in pregnant women and pregnancy outcomes.
Topics: Abnormalities, Drug-Induced; Anti-Ulcer Agents; Cimetidine; Cohort Studies; Female; Humans; Infant, | 1999 |
Evaluation of acetaminophen-induced developmental toxicity using FETAX.
Topics: Abnormalities, Drug-Induced; Acetaminophen; Animals; Biological Assay; Biotransformation; Carbon Mon | 1992 |
Outcome of pregnancy after first trimester exposure to H2 receptor antagonists.
Topics: Abnormalities, Drug-Induced; Cimetidine; Female; Histamine H2 Antagonists; Humans; Infant, Newborn; | 1991 |
Use of Frog Embryo Teratogenesis Assay-Xenopus and an exogenous metabolic activation system to evaluate the developmental toxicity of diphenylhydantoin.
Topics: Abnormalities, Drug-Induced; Animals; Biotransformation; Cimetidine; Cyclohexanes; Cyclohexenes; Dos | 1990 |