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cimetidine and Abnormalities, Drug-Induced

cimetidine has been researched along with Abnormalities, Drug-Induced in 7 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research Excerpts

ExcerptRelevanceReference
" Both p-HPPH and m-HPPH were much less developmentally toxic than DPH."1.28Use of Frog Embryo Teratogenesis Assay-Xenopus and an exogenous metabolic activation system to evaluate the developmental toxicity of diphenylhydantoin. ( Bantle, JA; Fort, DJ, 1990)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's4 (57.14)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matok, I1
Gorodischer, R1
Koren, G2
Sheiner, E1
Wiznitzer, A1
Uziel, E1
Levy, A1
Witter, FR1
King, TM1
Blake, DA1
Anand, S1
Van Thiel, DH1
Ruigómez, A1
García Rodríguez, LA1
Cattaruzzi, C1
Troncon, MG1
Agostinis, L1
Wallander, MA1
Johansson, S1
Fort, DJ2
Rayburn, JR1
Bantle, JA2
Zemlickis, DM1

Reviews

1 review available for cimetidine and Abnormalities, Drug-Induced

ArticleYear
The effects of chronic gastrointestinal medication on the fetus and neonate.
    Obstetrics and gynecology, 1981, Volume: 58, Issue:5 Suppl

    Topics: Abnormalities, Drug-Induced; Antacids; Antiemetics; Cathartics; Cimetidine; Colonic Diseases, Functi

1981

Other Studies

6 other studies available for cimetidine and Abnormalities, Drug-Induced

ArticleYear
The safety of H(2)-blockers use during pregnancy.
    Journal of clinical pharmacology, 2010, Volume: 50, Issue:1

    Topics: Abnormalities, Drug-Induced; Abortion, Therapeutic; Adolescent; Adult; Apgar Score; Cimetidine; Coho

2010
Prenatal and neonatal exposure to cimetidine results in gonadal and sexual dysfunction in adult males.
    Science (New York, N.Y.), 1982, Oct-29, Volume: 218, Issue:4571

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Suckling; Cimetidine; Female; Guanidines; Male; Pregn

1982
Use of cimetidine, omeprazole, and ranitidine in pregnant women and pregnancy outcomes.
    American journal of epidemiology, 1999, Sep-01, Volume: 150, Issue:5

    Topics: Abnormalities, Drug-Induced; Anti-Ulcer Agents; Cimetidine; Cohort Studies; Female; Humans; Infant,

1999
Evaluation of acetaminophen-induced developmental toxicity using FETAX.
    Drug and chemical toxicology, 1992, Volume: 15, Issue:4

    Topics: Abnormalities, Drug-Induced; Acetaminophen; Animals; Biological Assay; Biotransformation; Carbon Mon

1992
Outcome of pregnancy after first trimester exposure to H2 receptor antagonists.
    American journal of perinatology, 1991, Volume: 8, Issue:1

    Topics: Abnormalities, Drug-Induced; Cimetidine; Female; Histamine H2 Antagonists; Humans; Infant, Newborn;

1991
Use of Frog Embryo Teratogenesis Assay-Xenopus and an exogenous metabolic activation system to evaluate the developmental toxicity of diphenylhydantoin.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1990, Volume: 14, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Biotransformation; Cimetidine; Cyclohexanes; Cyclohexenes; Dos

1990