cimetidine has been researched along with Abnormalities, Autosome in 3 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine appears to be a useful candidate for the future development of post-irradiation radioprotectors." | 1.31 | Protective effects of cimetidine on radiation-induced micronuclei and apoptosis in human peripheral blood lymphocytes. ( Futatsuya, R; Kojima, Y; Kondo, T; Shoji, M; Zhao, QL, 2002) |
| "Cimetidine was administered at 15 mg/kg i." | 1.29 | Radioprotective effects of cimetidine in mouse bone marrow cells exposed to gamma-rays as assayed by the micronucleus test. ( Gharbali, A; Mozdarani, H, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Athanasiou, K | 1 |
| Kyrtopoulos, SA | 1 |
| Mozdarani, H | 1 |
| Gharbali, A | 1 |
| Kojima, Y | 1 |
| Kondo, T | 1 |
| Zhao, QL | 1 |
| Shoji, M | 1 |
| Futatsuya, R | 1 |
3 other studies available for cimetidine and Abnormalities, Autosome
| Article | Year |
|---|---|
Induction of sister chromatid exchanges and chromosome aberrations in cultured mammalian cells by N-nitrosocimetidine.
Topics: Animals; Cell Line; Chromosome Aberrations; Cimetidine; Cricetinae; Cricetulus; Crossing Over, Genet | 1981 |
Radioprotective effects of cimetidine in mouse bone marrow cells exposed to gamma-rays as assayed by the micronucleus test.
Topics: Animals; Bone Marrow Cells; Chromosome Aberrations; Chromosomes; Cimetidine; Dose-Response Relations | 1993 |
Protective effects of cimetidine on radiation-induced micronuclei and apoptosis in human peripheral blood lymphocytes.
Topics: Adult; Apoptosis; Caspase 3; Caspases; Chromosome Aberrations; Chromosomes; Cimetidine; Dose-Respons | 2002 |