Page last updated: 2024-09-03

cimadronate and Kahler Disease

cimadronate has been researched along with Kahler Disease in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's5 (62.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hayakawa, H; Hayakawa, M; Miwa, A; Takezako, N; Tominaga, S; Yanagisawa, K1
Iguchi, T; Ikeda, Y; Kizaki, M; Miyakawa, Y; Yamamoto, K1
Ashihara, E; Fuchida, S; Hatsuse, M; Ochiai, N; Okamoto, M; Okano, A; Shimazaki, C; Uchida, R; Yamada, N1
Ashihara, E; Fuchida, S; Inaba, T; Ochiai, N; Okamoto, M; Okano, A; Shimazaki, C; Uchida, R; Yamada, N1
Akamatsu, S; Horiike, S; Inaba, T; Kanamura, N; Nomura, K; Okamoto, M; Shimazaki, C; Shimura, K; Taniguchi, K; Taniwaki, M; Uchida, R1
Apperley, JF; Croucher, PI; Rogers, MJ; Russell, RG; Shipman, CM1
Croucher, PI; Helfrich, MH; Rogers, MJ; Russell, RG; Shipman, CM1
Ashihara, E; Hatsuse, M; Hirai, H; Inaba, T; Nakagawa, M; Okamoto, A; Okano, A; Shimazaki, C; Takahashi, R1

Trials

1 trial(s) available for cimadronate and Kahler Disease

ArticleYear
Combination therapy with thalidomide, incadronate, and dexamethasone for relapsed or refractory multiple myeloma.
    International journal of hematology, 2005, Volume: 82, Issue:3

    Topics: Aged; Angiogenesis Inhibitors; Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Dexamethasone; Diphosphonates; Disease-Free Survival; Female; Humans; Male; Middle Aged; Multiple Myeloma; Osteolysis; Recurrence; Thalidomide

2005

Other Studies

7 other study(ies) available for cimadronate and Kahler Disease

ArticleYear
YM-175 induces apoptosis of human native monocyte-lineage cells via inhibition of prenylation.
    American journal of hematology, 2012, Volume: 87, Issue:12

    Topics: Apoptosis; Bone Density Conservation Agents; Cell Line, Tumor; Diphosphonates; Humans; Monocytes; Multiple Myeloma; Prenylation

2012
Nitrogen-containing bisphosphonates induce S-phase cell cycle arrest and apoptosis of myeloma cells by activating MAPK pathway and inhibiting mevalonate pathway.
    Cellular signalling, 2003, Volume: 15, Issue:7

    Topics: Apoptosis; Cell Division; Cell Line, Tumor; Checkpoint Kinase 1; Diphosphonates; Diterpenes; Enzyme Inhibitors; Farnesol; Humans; Imidazoles; Interleukin-6; MAP Kinase Signaling System; Mevalonic Acid; Multiple Myeloma; Phosphorylation; Protein Kinases; S Phase; Signal Transduction; Stromal Cells

2003
Nitrogen-containing bisphosphonate incadronate augments the inhibitory effect of farnesyl transferase inhibitor tipifarnib on the growth of fresh and cloned myeloma cells in vitro.
    Leukemia & lymphoma, 2005, Volume: 46, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Diphosphonates; Dose-Response Relationship, Drug; Drug Synergism; Farnesyltranstransferase; Humans; Multiple Myeloma; Quinolones; Tumor Cells, Cultured

2005
Hyperbaric oxygen in addition to antibiotic therapy is effective for bisphosphonate-induced osteonecrosis of the jaw in a patient with multiple myeloma.
    International journal of hematology, 2006, Volume: 84, Issue:4

    Topics: Anti-Bacterial Agents; Diagnostic Imaging; Diphosphonates; Humans; Hyperbaric Oxygenation; Jaw Diseases; Male; Mandible; Middle Aged; Multiple Myeloma; Osteonecrosis; Pain; Treatment Outcome

2006
Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti-tumour activity.
    British journal of haematology, 1997, Volume: 98, Issue:3

    Topics: Apoptosis; Clodronic Acid; Diphosphonates; DNA, Neoplasm; Humans; Multiple Myeloma; Pamidronate; Tumor Cells, Cultured

1997
The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway.
    Cancer research, 1998, Dec-01, Volume: 58, Issue:23

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Diphosphonates; Diterpenes; Enzyme Inhibitors; Farnesol; Humans; Lovastatin; Mevalonic Acid; Multiple Myeloma; Protein Prenylation; Tumor Cells, Cultured

1998
A newly developed bisphosphonate, YM529, is a potent apoptosis inducer of human myeloma cells.
    Leukemia research, 2001, Volume: 25, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Division; Diphosphonates; Flow Cytometry; Humans; Imidazoles; Multiple Myeloma; Pamidronate; Tumor Cells, Cultured

2001