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cimadronate and Bone Loss, Osteoclastic

cimadronate has been researched along with Bone Loss, Osteoclastic in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (55.56)18.2507
2000's8 (44.44)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gossman, WL; Oldfield, E; Van Brussel, EM; Wilson, SR1
Akiyama, T; Cao, Y; Ito, M; Kaji, Y; Kawanishi, J; Komatsubara, S; Li, J; Mashiba, T; Miyamoto, K; Mori, S; Norimatsu, H1
Hiraga, T; Kitagawa, Y; Yoneda, T; Yura, Y1
Akiyama, T; Cao, Y; Dobashi, H; Komatsubara, S; Manabe, T; Mashiba, T; Miyamoto, K; Mori, S; Norimatsu, H; Tokuda, M1
Hirasawa, N; Hong, J; Ishihara, K; Kang, YS; Kwak, JH; Nakano, Y; Niikura, K; Oh, JS; Ohuchi, K; Sasaki, H; Yanai, M; Yokomakura, A; Zee, O1
Komatsubara, S; Marumo, K; Mashiba, T; Mori, S; Saito, M1
Abe, T; Kanoh, H; Kawashima, H; Motoie, H; Nakamura, T; Nishikawa, H; O'uchi, N1
Abe, M; Hakeda, Y; Kawashima, H; Kodama, H; Niida, S; Yamasaki, A1
Koiso, K; Nemoto, R; Nishijima, Y; Uchida, K1
Gen, M1
Hiraga, T; Nakajima, T; Ozawa, H; Tanaka, S; Yamamoto, M1
Barbier, A; Baron, R; David, P; Nguyen, H1
Funaba, Y; Kawabe, N; Nakadate-Matsushita, T; Tanahashi, M; Tateishi, A1
Fukushima, S; Kokubo, S; Shirahata, A; Takahashi, K; Teramura, K; Usuda, S1
Motoie, H; Nishikawa, H; O'uchi, N; Shikama, H1
Iorio, R; Kobayashi, S; Kojima, S; Mehdi, R; Nawata, M; Shimizu, T; Takaoka, K; Tsutsumimoto, T1
Brown, RJ; Grove, JE; Watts, DJ1
Abe, T; Itoi, E; Kasukawa, Y; Kudo, T; Miyakoshi, N; Sato, K; Tamura, Y; Tsuchida, T1

Other Studies

18 other study(ies) available for cimadronate and Bone Loss, Osteoclastic

ArticleYear
Hydronium (cycloheptylammonio)methylene-1,1-bisphosphonate (hydronium incadronate).
    Acta crystallographica. Section C, Crystal structure communications, 2003, Volume: 59, Issue:Pt 2

    Topics: Bone Resorption; Crystallography, X-Ray; Diphosphonates; Hydrogen Bonding; Hypercalcemia; Models, Molecular; Structure-Activity Relationship

2003
Long-term treatment of incadronate disodium accumulates microdamage but improves the trabecular bone microarchitecture in dog vertebra.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2003, Volume: 18, Issue:3

    Topics: Animals; Bone Resorption; Diphosphonates; Dogs; Female; Male; Spine; Tomography, X-Ray Computed

2003
Suppression by incadronate of invasion and growth of A-375 human melanoma in mandible in nude mice.
    Oncology reports, 2005, Volume: 13, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Resorption; Diphosphonates; Humans; Male; Mandibular Neoplasms; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous; Tumor Cells, Cultured

2005
Incadronate disodium inhibits joint destruction and periarticular bone loss only in the early phase of rat adjuvant-induced arthritis.
    Journal of bone and mineral metabolism, 2005, Volume: 23, Issue:4

    Topics: Animals; Arthritis, Experimental; Bone Resorption; Cartilage, Articular; Diphosphonates; Female; Radiography; Rats; Rats, Inbred Lew; Time Factors

2005
Inhibition of bone resorption in cultures of mouse calvariae by apicularen A.
    Planta medica, 2007, Volume: 73, Issue:2

    Topics: Animals; Bone Resorption; Bridged Bicyclo Compounds, Heterocyclic; Diphosphonates; Humans; Macrolides; Mice; Myxococcales; Parathyroid Hormone; Skull; Vacuolar Proton-Translocating ATPases

2007
Collagen maturity, glycation induced-pentosidine, and mineralization are increased following 3-year treatment with incadronate in dogs.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2008, Volume: 19, Issue:9

    Topics: Animals; Arginine; Biomechanical Phenomena; Bone Density Conservation Agents; Bone Resorption; Calcification, Physiologic; Calcium; Collagen; Diphosphonates; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Glycation End Products, Advanced; Lysine; Male; Phosphorus; Ribs

2008
Effects of the bisphosphonate YM175 on bone mineral density, strength, structure, and turnover in ovariectomized beagles on concomitant dietary calcium restriction.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1995, Volume: 10, Issue:6

    Topics: Administration, Oral; Alkaline Phosphatase; Analysis of Variance; Animals; Biomechanical Phenomena; Body Weight; Bone Density; Bone Development; Bone Resorption; Calcium; Dihydroxycholecalciferols; Diphosphonates; Dogs; Dose-Response Relationship, Drug; Female; Femur; Femur Neck; Humans; Lumbar Vertebrae; Osteoporosis, Postmenopausal; Ovariectomy; Random Allocation; Regression Analysis

1995
Transient recruitment of osteoclasts and expression of their function in osteopetrotic (op/op) mice by a single injection of macrophage colony-stimulating factor.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1993, Volume: 8, Issue:1

    Topics: Animals; Bone Resorption; Diphosphonates; Female; Macrophage Colony-Stimulating Factor; Male; Mice; Mice, Mutant Strains; Mutation; Osteoclasts; Osteopetrosis; Recombinant Proteins; Tibia

1993
Inhibition by a new bisphosphonate (YM175) of bone resorption induced by the MBT-2 tumour of mice.
    British journal of cancer, 1993, Volume: 67, Issue:5

    Topics: Animals; Bone Resorption; Carcinoma, Transitional Cell; Diphosphonates; Female; Humans; Male; Mice; Mice, Inbred C3H; Mice, Nude; Prostatic Neoplasms; Tumor Cells, Cultured

1993
[Effects of bisphosphonates on vitamin A-induced bone resorption in thyroparathyroidectomized rat].
    Nihon Seikeigeka Gakkai zasshi, 1995, Volume: 69, Issue:11

    Topics: Animals; Bone and Bones; Bone Resorption; Diphosphonates; Disease Models, Animal; Male; Parathyroidectomy; Rats; Rats, Sprague-Dawley; Thyroidectomy; Vitamin A

1995
Inhibitory effects of bisphosphonate (YM175) on bone resorption induced by a metastatic bone tumor.
    Bone, 1996, Volume: 18, Issue:1

    Topics: Acid Phosphatase; Animals; Biomarkers, Tumor; Bone Neoplasms; Bone Resorption; Diphosphonates; Humans; Immunohistochemistry; Isoenzymes; Male; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Tartrate-Resistant Acid Phosphatase; Tumor Cells, Cultured

1996
The bisphosphonate tiludronate is a potent inhibitor of the osteoclast vacuolar H(+)-ATPase.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1996, Volume: 11, Issue:10

    Topics: Alendronate; Animals; Binding, Competitive; Bone Resorption; Cell Membrane Permeability; Chickens; Diphosphonates; Dose-Response Relationship, Drug; Ethylmaleimide; Etidronic Acid; Female; Hydrogen-Ion Concentration; Kidney; Lethal Dose 50; Osteoclasts; Proton-Translocating ATPases; Saccharomyces cerevisiae; Synaptic Vesicles

1996
TRK-530 inhibits accumulation of superoxide anions derived from human polymorphonuclear leukocytes and bone resorption induced by activated osteoclasts.
    Pharmacology, 1998, Volume: 56, Issue:3

    Topics: Animals; Animals, Suckling; Antioxidants; Bone Resorption; Calcitriol; Calcium Channel Blockers; Diphosphonates; Dose-Response Relationship, Drug; Etidronic Acid; Hindlimb; Humans; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Osteoclasts; Risedronic Acid; Superoxides

1998
Effects of YM175, a new-generation bisphosphonate, on hypercalcemia induced by tumor-derived bone resorbing factors in rats.
    Japanese journal of pharmacology, 1998, Volume: 76, Issue:2

    Topics: Animals; Bone Resorption; Diphosphonates; Hypercalcemia; Interleukin-1; Male; Models, Biological; Neoplasms, Experimental; Parathyroid Hormone-Related Protein; Proteins; Rats; Rats, Wistar

1998
Morphometric evidence that YM175, a bisphosphonate, reduces trabecular bone resorption in ovariectomized dogs with dietary calcium restriction.
    Japanese journal of pharmacology, 1999, Volume: 79, Issue:3

    Topics: Animals; Bone Density; Bone Remodeling; Bone Resorption; Calcium, Dietary; Diphosphonates; Dogs; Female; Ovariectomy

1999
Advantages of concurrent use of anabolic and antiresorptive agents over single use of these agents in increasing trabecular bone volume, connectivity, and biomechanical competence of rat vertebrae.
    Bone, 1999, Volume: 25, Issue:6

    Topics: Animals; Biomechanical Phenomena; Bone Density; Bone Development; Bone Resorption; Diphosphonates; Drug Synergism; Estradiol; Humans; Lumbar Vertebrae; Male; Parathyroid Hormone; Rats; Rats, Wistar; Recombinant Proteins

1999
The intracellular target for the antiresorptive aminobisphosphonate drugs in Dictyostelium discoideum is the enzyme farnesyl diphosphate synthase.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2000, Volume: 15, Issue:5

    Topics: Alendronate; Alkyl and Aryl Transferases; Amino Acid Sequence; Animals; Base Sequence; Bone Resorption; Dictyostelium; Diphosphonates; DNA Primers; Etidronic Acid; Farnesyl-Diphosphate Farnesyltransferase; Geranyltranstransferase; Molecular Sequence Data; Risedronic Acid; RNA, Messenger; Sequence Homology, Amino Acid

2000
Long-term effects of withdrawal of bisphosphonate incadronate disodium (YM175) on bone mineral density, mass, structure, and turnover in the lumbar vertebrae of ovariectomized rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2001, Volume: 16, Issue:3

    Topics: Aging; Alkaline Phosphatase; Amino Acids; Animals; Biomarkers; Bone Density; Bone Resorption; Diphosphonates; Female; Lumbar Vertebrae; Osteoclasts; Ovariectomy; Rats; Rats, Sprague-Dawley

2001