Page last updated: 2024-10-25

cilostazol and Liver Cirrhosis

cilostazol has been researched along with Liver Cirrhosis in 3 studies

Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Research Excerpts

ExcerptRelevanceReference
"Carvacrol is a natural phenolic monoterpenoid, and cilostazol is a selective phosphodiesterase-3 inhibitor with antioxidant, anti-inflammatory and antiapoptotic effects."1.91Combined carvacrol and cilostazol ameliorate ethanol-induced liver fibrosis in rats: Possible role of SIRT1/Nrf2/HO-1 pathway. ( Abu-Risha, SE; Elbohoty, HR; Elsisi, AE; Sokar, SS, 2023)
"Induction of liver fibrosis in TAA-treated rats was observed as evidenced by the biochemical and histopathological findings."1.51Regression of fibrosis by cilostazol in a rat model of thioacetamide-induced liver fibrosis: Up regulation of hepatic cAMP, and modulation of inflammatory, oxidative stress and apoptotic biomarkers. ( Abdel Rahman, RF; Arbid, MS; Badawi, M; El Awdan, SA; El Marasy, SA; Hegazy, RR; Ibrahim, HM, 2019)
"Cilostazol is a phosphodiesterase III inhibitor increases adenosine 3', 5'-cyclic monophosphate (cyclic AMP) level which inhibits hepatic stellate cell activation."1.42Cilostazol attenuates cholestatic liver injury and its complications in common bile duct ligated rats. ( Abdel Kawy, HS, 2015)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Abu-Risha, SE1
Sokar, SS1
Elbohoty, HR1
Elsisi, AE1
El Awdan, SA1
Abdel Rahman, RF1
Ibrahim, HM1
Hegazy, RR1
El Marasy, SA1
Badawi, M1
Arbid, MS1
Abdel Kawy, HS1

Other Studies

3 other studies available for cilostazol and Liver Cirrhosis

ArticleYear
Combined carvacrol and cilostazol ameliorate ethanol-induced liver fibrosis in rats: Possible role of SIRT1/Nrf2/HO-1 pathway.
    International immunopharmacology, 2023, Volume: 116

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cilostazol; Cytokines; Ethanol; Liver; Liver Cirrho

2023
Regression of fibrosis by cilostazol in a rat model of thioacetamide-induced liver fibrosis: Up regulation of hepatic cAMP, and modulation of inflammatory, oxidative stress and apoptotic biomarkers.
    PloS one, 2019, Volume: 14, Issue:5

    Topics: Animals; Apoptosis; Biomarkers; Cilostazol; Cyclic AMP; Inflammation; Liver; Liver Cirrhosis; Oxidat

2019
Cilostazol attenuates cholestatic liver injury and its complications in common bile duct ligated rats.
    European journal of pharmacology, 2015, Apr-05, Volume: 752

    Topics: Actins; Animals; Cholestasis; Cilostazol; Common Bile Duct; Dose-Response Relationship, Drug; Hemogl

2015