Page last updated: 2024-10-25

cilostazol and Elevated Cholesterol

cilostazol has been researched along with Elevated Cholesterol in 10 studies

Research Excerpts

ExcerptRelevanceReference
"This study evaluated the efficacy of combined therapy with probucol and cilostazol on endothelial function in silent lacunar cerebral infarcts (SLCI) and mild hypercholesterolemia."9.19Combined therapeutic effect of probucol and cilostazol on endothelial function in patients with silent cerebral lacunar infarcts and hypercholesterolemia: a preliminary study. ( Hattori, H; Ishihara, M; Nagata, M; Takase, B; Tanaka, Y, 2014)
"The current study was designed to investigate whether combined use of probucol (an anti-oxidant agent) with cilostazol (a platelet aggregation inhibitor) would increase the inhibitory effect of statins (a lipid-lowering agent) on atherosclerosis in moderately hypercholesterolemic rabbits."7.81Combined use of probucol and cilostazol with atorvastatin attenuates atherosclerosis in moderately hypercholesterolemic rabbits. ( Bai, L; Chen, Y; Fan, J; Gao, S; Guan, H; Li, Y; Lin, Y; Liu, E; Sun, L; Wang, Y; Zhao, S; Zhu, N, 2015)
" In the present study, we investigated the beneficial effects of combinatorial therapy with probucol and cilostazol on focal cerebral ischemia with hypercholesterolemia."7.77Combinatorial effect of probucol and cilostazol in focal ischemic mice with hypercholesterolemia. ( Bae, SS; Choi, BT; Hong, KW; Kim, JH; Kim, YD; Park, KP; Park, SH; Shin, HK, 2011)
"This study evaluated the efficacy of combined therapy with probucol and cilostazol on endothelial function in silent lacunar cerebral infarcts (SLCI) and mild hypercholesterolemia."5.19Combined therapeutic effect of probucol and cilostazol on endothelial function in patients with silent cerebral lacunar infarcts and hypercholesterolemia: a preliminary study. ( Hattori, H; Ishihara, M; Nagata, M; Takase, B; Tanaka, Y, 2014)
"The current study was designed to investigate whether combined use of probucol (an anti-oxidant agent) with cilostazol (a platelet aggregation inhibitor) would increase the inhibitory effect of statins (a lipid-lowering agent) on atherosclerosis in moderately hypercholesterolemic rabbits."3.81Combined use of probucol and cilostazol with atorvastatin attenuates atherosclerosis in moderately hypercholesterolemic rabbits. ( Bai, L; Chen, Y; Fan, J; Gao, S; Guan, H; Li, Y; Lin, Y; Liu, E; Sun, L; Wang, Y; Zhao, S; Zhu, N, 2015)
" In the present study, we investigated the beneficial effects of combinatorial therapy with probucol and cilostazol on focal cerebral ischemia with hypercholesterolemia."3.77Combinatorial effect of probucol and cilostazol in focal ischemic mice with hypercholesterolemia. ( Bae, SS; Choi, BT; Hong, KW; Kim, JH; Kim, YD; Park, KP; Park, SH; Shin, HK, 2011)
"Hypercholesterolemia is associated with decreased nitric oxide (NO) bioavailability and endothelial dysfunction, a phenomenon thought to have a major role in the altered cerebral blood flow evident in stroke."1.36Alterations in nitric oxide and endothelin-1 bioactivity underlie cerebrovascular dysfunction in ApoE-deficient mice. ( Ahluwalia, A; Duchene, J; Hattori, N; Milsom, AB; Panayiotou, C; Urabe, T; Yamashiro, K, 2010)
"Cilostazol was then added in a cumulative manner (680-2,720 microg/L), and the tension generated was recorded."1.33Effects of cilostazol on human venous smooth muscle. ( Becker, RW; Kline, RA; Lusis, E; Sohn, RL, 2005)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's8 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takase, B1
Nagata, M1
Hattori, H1
Tanaka, Y1
Ishihara, M1
Kim, JH2
Hong, KW2
Bae, SS2
Shin, YI1
Choi, BT2
Shin, HK2
Wang, Y2
Bai, L2
Lin, Y2
Guan, H2
Zhu, N2
Chen, Y2
Li, Y2
Gao, S2
Zhao, S2
Fan, J2
Liu, E2
Sun, L1
da Motta, NA1
de Brito, FC1
Yamashiro, K1
Milsom, AB1
Duchene, J1
Panayiotou, C1
Urabe, T1
Hattori, N1
Ahluwalia, A1
Park, SH1
Kim, YD1
Park, KP1
Becker, RW1
Lusis, E1
Sohn, RL1
Kline, RA1
Yang, R1
Powell-Braxton, L1
Ogaoawara, AK1
Dybdal, N1
Bunting, S1
Ohneda, O1
Jin, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Effect of Cilostazol on the Clinical Outcomes of Rheumatoid Arthritis Patients[NCT05671497]Phase 2/Phase 370 participants (Anticipated)Interventional2022-11-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for cilostazol and Elevated Cholesterol

ArticleYear
Combined therapeutic effect of probucol and cilostazol on endothelial function in patients with silent cerebral lacunar infarcts and hypercholesterolemia: a preliminary study.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2014, Volume: 23, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Agents; Cholinergic Antagonists; Cilostazol; Drug T

2014

Other Studies

9 other studies available for cilostazol and Elevated Cholesterol

ArticleYear
Peripheral artery disease. Heart health for your legs.
    Mayo Clinic health letter (English ed.), 2014, Volume: 32, Issue:3

    Topics: Angioplasty, Balloon; Atherosclerosis; Cilostazol; Diabetes Complications; Exercise; Fibrinolytic Ag

2014
Probucol plus cilostazol attenuate hypercholesterolemia‑induced exacerbation in ischemic brain injury via anti-inflammatory effects.
    International journal of molecular medicine, 2014, Volume: 34, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Astrocytes; Brain Injuries; Brain Ischemia; CD11b Antigen; Cerebr

2014
Demonstration of an add-on effect of probucol and cilostazol on the statin-induced anti-atherogenic effects.
    Histology and histopathology, 2014, Volume: 29, Issue:12

    Topics: Animals; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Cilostazol; Drug Therapy, Combinat

2014
Combined use of probucol and cilostazol with atorvastatin attenuates atherosclerosis in moderately hypercholesterolemic rabbits.
    Lipids in health and disease, 2015, Jul-29, Volume: 14

    Topics: Animals; Aorta; Atherosclerosis; Atorvastatin; Biomarkers; Cilostazol; Drug Therapy, Combination; Hy

2015
Cilostazol exerts antiplatelet and anti-inflammatory effects through AMPK activation and NF-kB inhibition on hypercholesterolemic rats.
    Fundamental & clinical pharmacology, 2016, Volume: 30, Issue:4

    Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Cilostazol; Dose-Response Relation

2016
Alterations in nitric oxide and endothelin-1 bioactivity underlie cerebrovascular dysfunction in ApoE-deficient mice.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2010, Volume: 30, Issue:8

    Topics: Animals; Aorta; Apolipoproteins E; Cells, Cultured; Cilostazol; Cyclic GMP; Endothelin-1; Endotheliu

2010
Combinatorial effect of probucol and cilostazol in focal ischemic mice with hypercholesterolemia.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 338, Issue:2

    Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Cilostazol; Drug Therapy, Combination; Hyperch

2011
Effects of cilostazol on human venous smooth muscle.
    Annals of vascular surgery, 2005, Volume: 19, Issue:3

    Topics: Cilostazol; Diabetes Mellitus; Dose-Response Relationship, Drug; Humans; Hypercholesterolemia; Hyper

2005
Hypertension and endothelial dysfunction in apolipoprotein E knockout mice.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:11

    Topics: Age Factors; Animals; Apolipoproteins E; Arteriosclerosis; Cholesterol; Cilostazol; Endothelium, Vas

1999