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cilostazol and Diabetic Retinopathy

cilostazol has been researched along with Diabetic Retinopathy in 8 studies

Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effects of cilostazol, an antiplatelet and vasodilation agent, on the retinal function of patients with non-proliferative diabetic retinopathy (NPDR) using a full-field electroretinogram (ffERG)."7.83The effect of cilostazol on electrophysiologic changes in non-proliferative diabetic retinopathy patients. ( Kim, HD; Kim, YK; Lee, SH; Oh, JR; Ohn, YH, 2016)
"To explore the effect of cilostazol in the pathophysiology of diabetic retinopathy and its mechanism, we intraperitoneal injection streptozotocin (STZ) to induce rats diabetic model to study the alteration of the thrombospondin-1 (TSP-1) in the retina of diabetic rats, cilostazol treatment diabetic rats and normal rats by immunohistochemistry, real-time quantitative reverse transcription-polymerase chain reaction."7.74The effect of cilostazol on expression of thrombospondin-1 in diabetic retinopathy. ( Gu, YS; Teng, XD; Wang, JY; Yan, LP; Zhang, XM, 2008)
"Treatment with cilostazol significantly reduced the ROS levels in the AqH compared to the diabetic rats."5.51Cilostazol Attenuates Retinal Oxidative Stress and Inflammation in a Streptozotocin-Induced Diabetic Animal Model. ( Chang, SW; Huang, YH; Lin, CW; Wang, LC; Yang, CH; Yang, CM; Yang, WS; Yeh, PT, 2019)
"To evaluate the effects of cilostazol, an antiplatelet and vasodilation agent, on the retinal function of patients with non-proliferative diabetic retinopathy (NPDR) using a full-field electroretinogram (ffERG)."3.83The effect of cilostazol on electrophysiologic changes in non-proliferative diabetic retinopathy patients. ( Kim, HD; Kim, YK; Lee, SH; Oh, JR; Ohn, YH, 2016)
"To explore the effect of cilostazol in the pathophysiology of diabetic retinopathy and its mechanism, we intraperitoneal injection streptozotocin (STZ) to induce rats diabetic model to study the alteration of the thrombospondin-1 (TSP-1) in the retina of diabetic rats, cilostazol treatment diabetic rats and normal rats by immunohistochemistry, real-time quantitative reverse transcription-polymerase chain reaction."3.74The effect of cilostazol on expression of thrombospondin-1 in diabetic retinopathy. ( Gu, YS; Teng, XD; Wang, JY; Yan, LP; Zhang, XM, 2008)
"Treatment with cilostazol significantly reduced the ROS levels in the AqH compared to the diabetic rats."1.51Cilostazol Attenuates Retinal Oxidative Stress and Inflammation in a Streptozotocin-Induced Diabetic Animal Model. ( Chang, SW; Huang, YH; Lin, CW; Wang, LC; Yang, CH; Yang, CM; Yang, WS; Yeh, PT, 2019)
"Cilostazol treatment may be useful for the management of diabetic retinal vascular dysfunction and neuronal degeneration."1.39Neuroprotective effects of cilostazol on retinal ganglion cell damage in diabetic rats. ( Jung, KI; Kim, JH; Park, CK; Park, HY, 2013)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagai, N1
Deguchi, S1
Otake, H1
Hiramatsu, N1
Yamamoto, N1
Yeh, PT1
Huang, YH1
Chang, SW1
Wang, LC1
Yang, CM1
Yang, WS1
Lin, CW1
Yang, CH1
Jung, KI1
Kim, JH1
Park, HY1
Park, CK1
Kim, HD1
Lee, SH1
Kim, YK1
Oh, JR1
Ohn, YH1
Wang, JY1
Gu, YS1
Yan, LP1
Teng, XD1
Zhang, XM1
Hotta, N1
Nakamura, J1
Sakakibara, F1
Hamada, Y1
Hara, T1
Mori, K1
Nakashima, E1
Sasaki, H1
Kasama, N1
Inukai, S1
Koh, N1
Omoto, S1
Nomura, S1
Shouzu, A1
Hayakawa, T1
Shimizu, H1
Miyake, Y1
Yonemoto, T1
Nishikawa, M1
Fukuhara, S1
Inada, M1
Ahn, CW1
Lee, HC1
Park, SW1
Song, YD1
Huh, KB1
Oh, SJ1
Kim, YS1
Choi, YK1
Kim, JM1
Lee, TH1

Trials

1 trial available for cilostazol and Diabetic Retinopathy

ArticleYear
Decrease in carotid intima media thickness after 1 year of cilostazol treatment in patients with type 2 diabetes mellitus.
    Diabetes research and clinical practice, 2001, Volume: 52, Issue:1

    Topics: Blood Glucose; Blood Pressure; Carotid Artery, Common; Cilostazol; Coronary Disease; Diabetes Mellit

2001

Other Studies

7 other studies available for cilostazol and Diabetic Retinopathy

ArticleYear
Therapeutic Effect of Cilostazol Ophthalmic Nanodispersions on Retinal Dysfunction in Streptozotocin-Induced Diabetic Rats.
    International journal of molecular sciences, 2017, Sep-14, Volume: 18, Issue:9

    Topics: Animals; Cell Line; Cell Survival; Cilostazol; Diabetes Mellitus, Experimental; Diabetic Retinopathy

2017
Cilostazol Attenuates Retinal Oxidative Stress and Inflammation in a Streptozotocin-Induced Diabetic Animal Model.
    Current eye research, 2019, Volume: 44, Issue:3

    Topics: Animals; Aqueous Humor; Blood Glucose; Blotting, Western; Chemokine CCL2; Chemokine CX3CL1; Cilostaz

2019
Neuroprotective effects of cilostazol on retinal ganglion cell damage in diabetic rats.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 345, Issue:3

    Topics: Animals; Apoptosis; Blood Glucose; Blotting, Western; Body Weight; Cell Death; Cilostazol; Diabetic

2013
The effect of cilostazol on electrophysiologic changes in non-proliferative diabetic retinopathy patients.
    Documenta ophthalmologica. Advances in ophthalmology, 2016, Volume: 133, Issue:1

    Topics: Adult; Aged; Analysis of Variance; Atherosclerosis; Case-Control Studies; Cilostazol; Diabetes Melli

2016
The effect of cilostazol on expression of thrombospondin-1 in diabetic retinopathy.
    Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology, 2008, Volume: 41, Issue:4

    Topics: Animals; Cilostazol; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Immunohistochemistry; In

2008
Electroretinogram in sucrose-fed diabetic rats treated with an aldose reductase inhibitor or an anticoagulant.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: 2,3-Diphosphoglycerate; Aldehyde Reductase; Animals; Anticoagulants; Blood Glucose; Body Weight; Cil

1997
Significance of platelet-derived microparticles and activated platelets in diabetic nephropathy.
    Nephron, 1999, Volume: 81, Issue:3

    Topics: Antigens, CD; Blood Coagulation; Blood Platelets; Case-Control Studies; Cilostazol; Diabetic Nephrop

1999