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cilostazol and Diabetic Nephropathies

cilostazol has been researched along with Diabetic Nephropathies in 10 studies

Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.

Research Excerpts

ExcerptRelevanceReference
"We evaluated association between hyperinsulinemia/insulin resistance and microalbuminuria in the insulin-resistant Otsuka Long-Evans Tokushima Fatty (OLETF) rat."5.32Cilostazol, a phosphodiesterase inhibitor, reduces microalbuminuria in the insulin-resistant Otsuka Long-Evans Tokushima Fatty rat. ( Oshiro, Y; Shimabukuro, M; Shimajiri, Y; Takasu, N; Tohma, T; Yamakawa, M, 2004)
"Cilostazol was reported to lower the production of superoxide significantly in situ."1.36Cilostazol ameliorates nephropathy in type 1 diabetic rats involving improvement in oxidative stress and regulation of TGF-Beta and NF-kappaB. ( Chen, CC; Chen, HC; Lee, HJ; Lee, WC; Lin, PY; Ou, TT; Wang, CY; Wang, J; Wen, MC, 2010)
"Cilostazol was administered (27 or 9 mg kg(-1)d(-1)) to streptozotocin (STZ)-induced diabetic rats for eight weeks."1.35Intervention with cilostazol attenuates renal inflammation in streptozotocin-induced diabetic rats. ( Cao, M; Cheng, L; Gao, L; Guo, R; Hu, J; Li, M; Wang, F; Zhang, T; Zhang, X; Zhao, J, 2008)
"We evaluated association between hyperinsulinemia/insulin resistance and microalbuminuria in the insulin-resistant Otsuka Long-Evans Tokushima Fatty (OLETF) rat."1.32Cilostazol, a phosphodiesterase inhibitor, reduces microalbuminuria in the insulin-resistant Otsuka Long-Evans Tokushima Fatty rat. ( Oshiro, Y; Shimabukuro, M; Shimajiri, Y; Takasu, N; Tohma, T; Yamakawa, M, 2004)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's4 (40.00)29.6817
2010's4 (40.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Kim, SK1
Kim, G1
Choi, BH1
Ryu, D1
Ku, SK1
Kwak, MK1
Daimon, S1
Jiao, XM1
Jiao, XJ1
Zhang, XG1
Xu, XP1
Wu, JX1
Yao, L1
Zhao, J2
Lü, XF1
Asal, NJ1
Wojciak, KA1
Wang, F1
Li, M1
Cheng, L1
Zhang, T1
Hu, J1
Cao, M1
Guo, R1
Gao, L1
Zhang, X1
Lee, WC1
Chen, HC1
Wang, CY1
Lin, PY1
Ou, TT1
Chen, CC1
Wen, MC1
Wang, J1
Lee, HJ1
Tohma, T1
Shimabukuro, M1
Oshiro, Y1
Yamakawa, M1
Shimajiri, Y1
Takasu, N1
Rosa, MP1
Baroni, GV1
Portal, VL1
Omoto, S2
Nomura, S1
Shouzu, A2
Hayakawa, T2
Shimizu, H2
Miyake, Y2
Yonemoto, T1
Nishikawa, M2
Fukuhara, S1
Inada, M2

Reviews

2 reviews available for cilostazol and Diabetic Nephropathies

ArticleYear
Effect of cilostazol in treating diabetes-associated microvascular complications.
    Endocrine, 2017, Volume: 56, Issue:2

    Topics: Cilostazol; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Humans; Tetrazoles

2017
[Potential therapeutic approaches for prevention and treatment of diabetic nephropathy and neuropathy: evidences of cilostazol].
    Arquivos brasileiros de endocrinologia e metabologia, 2007, Volume: 51, Issue:9

    Topics: Cilostazol; Diabetic Nephropathies; Fibrinolytic Agents; Humans; Phosphodiesterase Inhibitors; Plate

2007

Trials

2 trials available for cilostazol and Diabetic Nephropathies

ArticleYear
Cilostazol reduces microalbuminuria in type 2 diabetic nephropathy.
    Chinese medical journal, 2013, Volume: 126, Issue:22

    Topics: Albuminuria; Cilostazol; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Tetrazoles

2013
Effects of beraprost and cilostazol and renal function on serum thrombomodulin levels in diabetic patients.
    Arzneimittel-Forschung, 2000, Volume: 50, Issue:6

    Topics: Cilostazol; Creatinine; Diabetes Mellitus; Diabetic Nephropathies; Epoprostenol; Humans; Kidney Func

2000

Other Studies

6 other studies available for cilostazol and Diabetic Nephropathies

ArticleYear
Negative correlation of urinary miR-199a-3p level with ameliorating effects of sarpogrelate and cilostazol in hypertensive diabetic nephropathy.
    Biochemical pharmacology, 2021, Volume: 184

    Topics: Animals; Biomarkers, Pharmacological; Cilostazol; Diabetic Nephropathies; Disease Models, Animal; Hy

2021
Adverse Effect of Antithrombotic Medications on Bleeding Events and Comparison of Antithrombotic Agents in Hemodialysis Patients.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2019, Volume: 23, Issue:1

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Diabetic Nephropathies; Drug Monitoring; Female; Fibrinolyti

2019
Intervention with cilostazol attenuates renal inflammation in streptozotocin-induced diabetic rats.
    Life sciences, 2008, Dec-19, Volume: 83, Issue:25-26

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemokine CCL2; Cilostazol; Diabetes Mellitus, Exp

2008
Cilostazol ameliorates nephropathy in type 1 diabetic rats involving improvement in oxidative stress and regulation of TGF-Beta and NF-kappaB.
    Bioscience, biotechnology, and biochemistry, 2010, Volume: 74, Issue:7

    Topics: Animals; Blood Glucose; Body Weight; Cilostazol; Creatinine; Diabetes Mellitus, Type 1; Diabetic Nep

2010
Cilostazol, a phosphodiesterase inhibitor, reduces microalbuminuria in the insulin-resistant Otsuka Long-Evans Tokushima Fatty rat.
    Metabolism: clinical and experimental, 2004, Volume: 53, Issue:11

    Topics: Albuminuria; Animals; Blood Glucose; Cilostazol; Collagen Type I; Diabetic Nephropathies; Fibronecti

2004
Significance of platelet-derived microparticles and activated platelets in diabetic nephropathy.
    Nephron, 1999, Volume: 81, Issue:3

    Topics: Antigens, CD; Blood Coagulation; Blood Platelets; Case-Control Studies; Cilostazol; Diabetic Nephrop

1999