Page last updated: 2024-10-25

cilostazol and Coronary Thrombosis

cilostazol has been researched along with Coronary Thrombosis in 22 studies

Coronary Thrombosis: Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Cilostazol has been reported to control restenosis after balloon angioplasty (BA)."6.71Balloon angioplasty plus cilostazol administration versus primary stenting of small coronary artery disease: final results of COMPASS. ( Awata, N; Kobayashi, T; Nasu, K; Takeda, Y; Tsuchikane, E, 2004)
"Cilostazol, which was administered to prevent subacute stent thrombosis after percutaneous coronary intervention, might have contributed to the transient intraventricular obstruction."5.34Dynamic intraventricular obstruction in acute myocardial infarction with administration of cilostazol. ( Hoyano, M; Maeda, C; Miida, T; Oda, H; Ozaki, K; Takahashi, K; Takayama, T; Tsuchida, K; Yanagawa, T, 2007)
"Cilostazol has been reported to control restenosis after balloon angioplasty (BA)."2.71Balloon angioplasty plus cilostazol administration versus primary stenting of small coronary artery disease: final results of COMPASS. ( Awata, N; Kobayashi, T; Nasu, K; Takeda, Y; Tsuchikane, E, 2004)
"Cilostazol is a potent antiplatelet agent with less serious side effects."2.69Comparison of cilostazol versus ticlopidine therapy after stent implantation. ( Hong, MK; Kim, HS; Kim, JJ; Lee, CW; Lee, HJ; Park, HK; Park, SJ; Park, SW, 1999)
" The included end-points were major adverse cardiovascular event (MACE), target lesion revascularization (TLR), target vessel revascularization (TVR), death, myocardial infarction (MI), stent thrombosis, bleeding and other drug adverse events."2.50Long-term clinical efficacy and safety of adding cilostazol to dual antiplatelet therapy for patients undergoing PCI: a meta-analysis of randomized trials with adjusted indirect comparisons. ( Chen, Y; Huang, X; Tang, Y; Xie, Y; Zhang, Y, 2014)
"Cilostazol is a vasodilating antiplatelet agent that reversibly inhibits platelet aggregation induced by many factors."2.41Cilostazol for prevention of thrombosis and restenosis after intracoronary stenting. ( El-Beyrouty, C; Spinler, SA, 2001)
"Cilostazol has also been reported to inhibit smooth muscle cell proliferation in vitro and has been demonstrated in a clinical study to favorably alter plasma lipids: to decrease triglyceride and to increase HDL-cholesterol levels."2.41Cilostazol (pletal): a dual inhibitor of cyclic nucleotide phosphodiesterase type 3 and adenosine uptake. ( Kambayashi Ji, J; Liu, Y; Shakur, Y; Yoshitake, M, 2001)
"6 months, major adverse cardiac and cerebrovascular events (MACCE) occurred in 43 patients (17."1.39Long-term effectiveness and safety of triple versus dual antiplatelet therapy after percutaneous coronary intervention for unprotected left main coronary artery disease. ( Choi, RK; Hwang, HK; Lee, HJ; Li, H; Park, JS; Ro, YM; Yu, CW, 2013)
"Cilostazol, which was administered to prevent subacute stent thrombosis after percutaneous coronary intervention, might have contributed to the transient intraventricular obstruction."1.34Dynamic intraventricular obstruction in acute myocardial infarction with administration of cilostazol. ( Hoyano, M; Maeda, C; Miida, T; Oda, H; Ozaki, K; Takahashi, K; Takayama, T; Tsuchida, K; Yanagawa, T, 2007)
"Cilostazol is an effective antiplatelet agent with minimum side effects after elective, bailout, or primary stent implantation."1.30Antiplatelet treatment with cilostazol after stent implantation. ( Kojima, S; Kuramochi, M; Matsumoto, Y; Sugi, T; Yano, M; Yoshitomi, Y, 1998)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.55)18.7374
1990's4 (18.18)18.2507
2000's11 (50.00)29.6817
2010's6 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, HJ2
Yu, CW1
Hwang, HK1
Choi, RK1
Park, JS1
Li, H1
Ro, YM1
Park, KW1
Kang, SH1
Park, JJ1
Yang, HM1
Kang, HJ1
Koo, BK1
Park, BE1
Cha, KS1
Rhew, JY1
Jeon, HK1
Shin, ES1
Oh, JH1
Jeong, MH3
Kim, S1
Hwang, KK1
Yoon, JH2
Lee, SY1
Park, TH1
Moon, KW1
Kwon, HM1
Chae, IH2
Kim, HS2
Chen, Y1
Zhang, Y1
Tang, Y1
Huang, X1
Xie, Y1
Im, E1
Lee, SH1
Kim, JS1
Choi, D1
Jang, Y1
Jang, SW1
Kim, DB1
Kwon, BJ1
Shin, D1
Her, SH1
Park, CS1
Park, HJ1
Park, MW1
Cho, EJ1
Rho, TH1
Kim, JH2
Grove, EL1
Kristensen, SD1
Chen, KY1
Rha, SW1
Li, YJ1
Poddar, KL1
Jin, Z1
Minami, Y1
Wang, L1
Kim, EJ1
Park, CG1
Seo, HS1
Oh, DJ1
Ahn, YK1
Hong, TJ1
Kim, YJ1
Hur, SH1
Seong, IW1
Chae, JK1
Cho, MC1
Bae, JH1
Choi, DH1
Jang, YS1
Kim, CJ1
Chung, WS1
Seung, KB1
Park, SJ3
Park, KH1
Lee, MG1
Ko, JS1
Sim, DS1
Yoon, NS1
Yoon, HJ1
Hong, YJ1
Kim, KH1
Park, HW1
Ahn, Y1
Cho, JG1
Park, JC1
Kang, JC1
Jeong, YH1
Park, Y1
Muse, WC1
Kwon, TJ1
Koh, JS1
Hwang, SJ1
Kwak, CH1
Hwang, JY1
Hong, MK2
Mintz, GS1
Lee, CW2
Kim, YH1
Lee, SW1
Song, JM1
Han, KH1
Kang, DH1
Song, JK1
Kim, JJ2
Park, SW2
Tsuchikane, E1
Takeda, Y1
Nasu, K1
Awata, N1
Kobayashi, T1
Schleinitz, MD1
Olkin, I1
Heidenreich, PA1
Holmes, DR1
Patel, TN1
Kreindel, M1
Lincoff, AM1
Ozaki, K1
Maeda, C1
Takayama, T1
Hoyano, M1
Yanagawa, T1
Tsuchida, K1
Takahashi, K1
Miida, T1
Oda, H1
Saitoh, S1
Saito, T1
Otake, A1
Owada, T1
Mitsugi, M1
Hashimoto, H1
Maruyama, Y1
Ochiai, M1
Isshiki, T1
Takeshita, S1
Eto, K1
Toyoizumi, H1
Sato, T1
Miyashita, H1
Yoshitomi, Y1
Kojima, S1
Sugi, T1
Yano, M1
Matsumoto, Y1
Kuramochi, M1
Park, HK1
El-Beyrouty, C1
Spinler, SA1
Liu, Y1
Shakur, Y1
Yoshitake, M1
Kambayashi Ji, J1
Murohara, Y1
Takatsu, Y1
Yui, Y1
Kawai, C1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Efficacy and Safety of New Platform Everolimus-eluting Coronary Stent System (Promus Element) With Zotarolimus-eluting Coronary Stent System (Endeavor Resolute) and Triple Anti-platelet Therapy With Double-dose Clopidogrel Anti-platelet [NCT01267734]Phase 43,750 participants (Anticipated)Interventional2010-06-30Recruiting
Study of the Efficacy and Safety of Cilostazol in the Prevention of Ischemic Vascular Events in Diabetic Patients With Symptomatic Peripheral Artery Disease.[NCT02983214]Phase 4826 participants (Actual)Interventional2016-11-30Completed
Randomized, Prospective , Open Label, Phase 4 Trial of Efficacy and Safety of Adjunctive Cilostazol in Acute Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention With Drug-eluting Stent[NCT01261832]Phase 4951 participants (Anticipated)Interventional2011-07-31Active, not recruiting
Revascularization With Paclitaxel-coated Balloon Angioplasty Versus Drug-eluting Stenting in Acute Myocardial Infarction - a Randomized Controlled Trial.[NCT02219802]120 participants (Anticipated)Interventional2014-08-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for cilostazol and Coronary Thrombosis

ArticleYear
Long-term clinical efficacy and safety of adding cilostazol to dual antiplatelet therapy for patients undergoing PCI: a meta-analysis of randomized trials with adjusted indirect comparisons.
    Current medical research and opinion, 2014, Volume: 30, Issue:1

    Topics: Aspirin; Cilostazol; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Hemorrhage; Humans

2014
Update on oral antiplatelet therapy: principles, problems and promises.
    Future cardiology, 2009, Volume: 5, Issue:3

    Topics: Adenosine; Administration, Oral; Cardiovascular Diseases; Cilostazol; Coronary Artery Disease; Coron

2009
Cilostazol, clopidogrel or ticlopidine to prevent sub-acute stent thrombosis: a meta-analysis of randomized trials.
    American heart journal, 2004, Volume: 148, Issue:6

    Topics: Anticoagulants; Aspirin; Cilostazol; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Hu

2004
Cilostazol for prevention of thrombosis and restenosis after intracoronary stenting.
    The Annals of pharmacotherapy, 2001, Volume: 35, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cilostazol; Coronary Disease; Coronary Restenosis;

2001
Cilostazol (pletal): a dual inhibitor of cyclic nucleotide phosphodiesterase type 3 and adenosine uptake.
    Cardiovascular drug reviews, 2001,Winter, Volume: 19, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Angioplasty, Balloon, Coronary; Animals; Arterial Oc

2001

Trials

3 trials available for cilostazol and Coronary Thrombosis

ArticleYear
Adjunctive cilostazol versus double-dose clopidogrel after drug-eluting stent implantation: the HOST-ASSURE randomized trial (Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis-Safety & Effectiveness of Drug-Eluting Stents & Anti-plate
    JACC. Cardiovascular interventions, 2013, Volume: 6, Issue:9

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy,

2013
Balloon angioplasty plus cilostazol administration versus primary stenting of small coronary artery disease: final results of COMPASS.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2004, Volume: 63, Issue:1

    Topics: Aged; Angioplasty, Balloon; Blood Vessel Prosthesis Implantation; Cilostazol; Combined Modality Ther

2004
Comparison of cilostazol versus ticlopidine therapy after stent implantation.
    The American journal of cardiology, 1999, Sep-01, Volume: 84, Issue:5

    Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Coronary Disease; Coronary Thrombo

1999

Other Studies

14 other studies available for cilostazol and Coronary Thrombosis

ArticleYear
Long-term effectiveness and safety of triple versus dual antiplatelet therapy after percutaneous coronary intervention for unprotected left main coronary artery disease.
    Coronary artery disease, 2013, Volume: 24, Issue:7

    Topics: Aged; Cerebrovascular Disorders; Cilostazol; Coronary Restenosis; Coronary Stenosis; Coronary Thromb

2013
Drug-eluting stent thrombosis after cilostazol withdrawal in a patient previously treated with triple antiplatelet therapy.
    International journal of cardiology, 2009, Jun-26, Volume: 135, Issue:2

    Topics: Aged; Cilostazol; Coronary Thrombosis; Digestive System Surgical Procedures; Drug-Eluting Stents; Hu

2009
Death caused by simultaneous subacute stent thrombosis of sirolimus-eluting stents in left anterior descending artery and left circumflex artery.
    International journal of cardiology, 2010, Apr-01, Volume: 140, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Occ

2010
Triple versus dual antiplatelet therapy in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.
    Circulation, 2009, Jun-30, Volume: 119, Issue:25

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Combined Modality Therapy; C

2009
What is the optimal duration of triple anti-platelet therapy in patients with acute myocardial infarction undergoing drug-eluting stent implantation?
    Journal of cardiology, 2011, Volume: 57, Issue:1

    Topics: Aspirin; Cilostazol; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Female; Follow-Up Studie

2011
Pharmacodynamic effect of clopidogrel therapy and switching to cilostazol in patients with the CYP2C19 loss-of-function allele (ACCEL-SWITCH) study.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:8

    Topics: Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Asian People; Aspirin; Cilostazol; Cl

2012
Incidence, mechanism, predictors, and long-term prognosis of late stent malapposition after bare-metal stent implantation.
    Circulation, 2004, Feb-24, Volume: 109, Issue:7

    Topics: Aged; Aspirin; Atherectomy, Coronary; Catheterization; Cilostazol; Combined Modality Therapy; Corona

2004
Antiplatelet therapy after percutaneous coronary intervention.
    Cerebrovascular diseases (Basel, Switzerland), 2006, Volume: 21 Suppl 1

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Coronary Thrombosis; Drug Resistan

2006
Use of ticlopidine and cilostazol after intracoronary drug-eluting stent placement in a patient with previous clopidogrel-induced thrombotic thrombocytopenic purpura: a case report.
    The Journal of invasive cardiology, 2006, Volume: 18, Issue:7

    Topics: ADAM Proteins; ADAMTS1 Protein; Aged; Apoptosis; Aspirin; Autoantibodies; Cilostazol; Clopidogrel; C

2006
Dynamic intraventricular obstruction in acute myocardial infarction with administration of cilostazol.
    Circulation journal : official journal of the Japanese Circulation Society, 2007, Volume: 71, Issue:4

    Topics: Acute Disease; Aged; Cilostazol; Coronary Angiography; Coronary Thrombosis; Echocardiography; Electr

2007
Cilostazol, a novel cyclic AMP phosphodiesterase inhibitor, prevents reocclusion after coronary arterial thrombolysis with recombinant tissue-type plasminogen activator.
    Arteriosclerosis and thrombosis : a journal of vascular biology, 1993, Volume: 13, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cilostazol; Coronary Thrombosis; Coronary Vessels; Dog

1993
Use of cilostazol, a novel antiplatelet agent, in a post-Palmaz-Schatz stenting regimen.
    The American journal of cardiology, 1997, Jun-01, Volume: 79, Issue:11

    Topics: Adult; Aged; Cilostazol; Coronary Angiography; Coronary Thrombosis; Female; Humans; Male; Middle Age

1997
Antiplatelet treatment with cilostazol after stent implantation.
    Heart (British Cardiac Society), 1998, Volume: 80, Issue:4

    Topics: Aged; Cilostazol; Coronary Disease; Coronary Thrombosis; Evaluation Studies as Topic; Female; Follow

1998
[The mode of action and clinical applications of phosphodiesterase inhibitors as anti-platelet drugs].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 47, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cilostazol; Coronary Disease; Coronary Thrombosis; Cyclic AMP;

1989