Page last updated: 2024-10-25

cilostazol and Coronary Artery Disease

cilostazol has been researched along with Coronary Artery Disease in 45 studies

Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.

Research Excerpts

ExcerptRelevanceReference
"Fifty-one patients with coronary artery disease (CAD) were assigned to one of two groups: the Cilostazol(+) group (with cilostazol) and Cilostazol(-) group (without cilostazol)."9.22The Effect of Cilostazol on Endothelial Function as Assessed by Flow-Mediated Dilation in Patients with Coronary Artery Disease. ( Ebato, M; Iso, Y; Maeda, A; Mori, H; Sasai, M; Sato, T; Suzuki, H; Tashiro, K; Wakabayashi, K, 2016)
"This is a post-hoc analysis derived from patients (n = 79) enrolled in a prospective, randomized, double-blind, double-dummy, crossover study comparing cilostazol with placebo in stable coronary artery disease patients on aspirin and clopidogrel therapy."9.17Pharmacodynamic effects of adjunctive cilostazol therapy in patients with coronary artery disease on dual antiplatelet therapy: impact of high on-treatment platelet reactivity and diabetes mellitus status. ( Angiolillo, DJ; Capodanno, D; Capranzano, P; Darlington, A; Desai, B; Dharmashankar, K; Ferreiro, JL; Rollini, F; Tello-Montoliu, A; Ueno, M, 2013)
"We sought to evaluate the impact of cilostazol on neointimal hyperplasia after drug-eluting stent (DES) implantation in patients with diabetes mellitus (DM)."9.13Drug-eluting stenting followed by cilostazol treatment reduces late restenosis in patients with diabetes mellitus the DECLARE-DIABETES Trial (A Randomized Comparison of Triple Antiplatelet Therapy with Dual Antiplatelet Therapy After Drug-Eluting Stent Im ( Cho, YH; Choi, SW; Chun, KJ; Hong, MK; Kim, HS; Kim, JH; Kim, YH; Ko, JK; Lee, CW; Lee, JH; Lee, NH; Lee, SW; Park, DW; Park, JH; Park, SJ; Park, SW; Seong, IW; Yun, SC, 2008)
"Patients with type 2 diabetes mellitus (T2DM) have reduced platelet inhibition compared with non-diabetics following P2Y(12) receptor blockade."6.73A randomized study assessing the impact of cilostazol on platelet function profiles in patients with diabetes mellitus and coronary artery disease on dual antiplatelet therapy: results of the OPTIMUS-2 study. ( Angiolillo, DJ; Aslam, M; Bass, TA; Box, LC; Capranzano, P; Charlton, RK; Desai, B; Goto, S; Guzman, LA; Shoemaker, SB; Suzuki, Y; Zenni, MM, 2008)
"Cilostazol has been reported to control restenosis after balloon angioplasty (BA)."6.71Balloon angioplasty plus cilostazol administration versus primary stenting of small coronary artery disease: final results of COMPASS. ( Awata, N; Kobayashi, T; Nasu, K; Takeda, Y; Tsuchikane, E, 2004)
"Previously, in the ESCAPE study, a randomized controlled trial, we found that 12 months of cilostazol administration significantly decreased coronary artery stenosis and the noncalcified plaque component compared with aspirin."5.51Cilostazol treatment for preventing adverse cardiovascular events in patients with type 2 diabetes and coronary atherosclerosis: Long-term follow-up of the ESCAPE study. ( Chun, EJ; Lim, S; Sohn, M, 2022)
"Hypercholesterolemic patients with coronary artery disease were randomized to three groups and received study drugs for 3 years: the control with statin alone; the probucol group with statin and probucol; and the combo group with statin, probucol, and cilostazol."5.41Effect of Probucol and/or Cilostazol on Carotid Intima Media Thickness in Patients with Coronary Heart Disease: A Randomized, Multicenter, Multinational Study. ( Ge, J; Kang, HJ; Kim, CH; Kim, MH; Kim, SH; Oh, BH; Park, JE; Sung, J, 2021)
"Cilostazol has been reported to control neointimal proliferation after stenting."5.31Debulking and stenting versus debulking only of coronary artery disease in patients treated with cilostazol (final results of ESPRIT). ( Awata, N; Kobayashi, T; Otsuji, S; Sakurai, M; Takeda, Y; Tsuchikane, E, 2002)
"Cilostazol, a phosphodiesterase III inhibitor, has vasodilating and antiplatelet properties with a low rate of bleeding complications."5.22Update on Cilostazol: A Critical Review of Its Antithrombotic and Cardiovascular Actions and Its Clinical Applications. ( Manolis, AA; Manolis, AS; Manolis, TA; Melita, H; Mikhailidis, DP, 2022)
"Fifty-one patients with coronary artery disease (CAD) were assigned to one of two groups: the Cilostazol(+) group (with cilostazol) and Cilostazol(-) group (without cilostazol)."5.22The Effect of Cilostazol on Endothelial Function as Assessed by Flow-Mediated Dilation in Patients with Coronary Artery Disease. ( Ebato, M; Iso, Y; Maeda, A; Mori, H; Sasai, M; Sato, T; Suzuki, H; Tashiro, K; Wakabayashi, K, 2016)
"This is a post-hoc analysis derived from patients (n = 79) enrolled in a prospective, randomized, double-blind, double-dummy, crossover study comparing cilostazol with placebo in stable coronary artery disease patients on aspirin and clopidogrel therapy."5.17Pharmacodynamic effects of adjunctive cilostazol therapy in patients with coronary artery disease on dual antiplatelet therapy: impact of high on-treatment platelet reactivity and diabetes mellitus status. ( Angiolillo, DJ; Capodanno, D; Capranzano, P; Darlington, A; Desai, B; Dharmashankar, K; Ferreiro, JL; Rollini, F; Tello-Montoliu, A; Ueno, M, 2013)
"We sought to evaluate the impact of cilostazol on neointimal hyperplasia after drug-eluting stent (DES) implantation in patients with diabetes mellitus (DM)."5.13Drug-eluting stenting followed by cilostazol treatment reduces late restenosis in patients with diabetes mellitus the DECLARE-DIABETES Trial (A Randomized Comparison of Triple Antiplatelet Therapy with Dual Antiplatelet Therapy After Drug-Eluting Stent Im ( Cho, YH; Choi, SW; Chun, KJ; Hong, MK; Kim, HS; Kim, JH; Kim, YH; Ko, JK; Lee, CW; Lee, JH; Lee, NH; Lee, SW; Park, DW; Park, JH; Park, SJ; Park, SW; Seong, IW; Yun, SC, 2008)
"Cilostazol is the only first-line medication for treating intermittent claudication, and the controlled-release (CR) formulation is associated with a lower prevalence of adverse events (AEs)."4.31Real-World Safety and Effectiveness of Controlled-Release Cilostazol in Patients with Symptomatic Peripheral Artery Disease. ( Kim, JH; Lee, HJ; Shin, WY, 2023)
" Sex-specific odds ratios of age, diabetes mellitus (DM), hypertension (HTN), coronary artery disease (CAD), cerebral vascular accident (CVA), or using cilostazol for LEA or PRP were explored."3.77Determinants of lower extremity amputation or revascularization procedure in patients with peripheral artery diseases: a population-based investigation. ( Chen, JJ; Lee, CH; Liau, CS; Lin, LY, 2011)
"Patients with type 2 diabetes mellitus (T2DM) have reduced platelet inhibition compared with non-diabetics following P2Y(12) receptor blockade."2.73A randomized study assessing the impact of cilostazol on platelet function profiles in patients with diabetes mellitus and coronary artery disease on dual antiplatelet therapy: results of the OPTIMUS-2 study. ( Angiolillo, DJ; Aslam, M; Bass, TA; Box, LC; Capranzano, P; Charlton, RK; Desai, B; Goto, S; Guzman, LA; Shoemaker, SB; Suzuki, Y; Zenni, MM, 2008)
"Cilostazol has been reported to control restenosis after balloon angioplasty (BA)."2.71Balloon angioplasty plus cilostazol administration versus primary stenting of small coronary artery disease: final results of COMPASS. ( Awata, N; Kobayashi, T; Nasu, K; Takeda, Y; Tsuchikane, E, 2004)
" Endpoints included major adverse cardiac effects (MACEs), target lesion revascularization (TLR), target vessel revascularization (TVR), death, stent thrombosis, bleeding and adverse drug reactions during a 9-12 months period, as well as platelet activities."2.52Comparing the effectiveness and safety between triple antiplatelet therapy and dual antiplatelet therapy in type 2 diabetes mellitus patients after coronary stents implantation: a systematic review and meta-analysis of randomized controlled trials. ( Bundhun, PK; Chen, MH; Qin, T, 2015)
" There is also no significant difference in major adverse cardiac and cerebrovascular events between the 2 therapies, except the smaller occurrence rate of target-lesion revascularization in the triple-therapy group (OR: 0."2.48The effectiveness and safety of triple-antiplatelet treatment based on cilostazol for patients receiving percutaneous coronary intervention: a meta-analysis. ( He, J; He, Y; Liu, G; Ma, C; Tang, P; Wang, P; Yang, J; Zhou, R; Zhou, S, 2012)
"Colchicine is a microtubule-destabilizing agent that may enhance the synthesis of cAMP."1.72Cardiovascular Protection Associated With Cilostazol, Colchicine, and Target of Rapamycin Inhibitors. ( Adeva-Andany, MM; Carneiro-Freire, N; Castro-Quintela, E; Fernández-Fernández, C; González-Lucán, M; Vila-Altesor, M, 2022)
"Cilostazol has been reported to control neointimal proliferation after stenting."1.31Debulking and stenting versus debulking only of coronary artery disease in patients treated with cilostazol (final results of ESPRIT). ( Awata, N; Kobayashi, T; Otsuji, S; Sakurai, M; Takeda, Y; Tsuchikane, E, 2002)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (26.67)29.6817
2010's27 (60.00)24.3611
2020's6 (13.33)2.80

Authors

AuthorsStudies
Manolis, AA1
Manolis, TA1
Melita, H1
Mikhailidis, DP1
Manolis, AS1
Adeva-Andany, MM1
Fernández-Fernández, C1
Carneiro-Freire, N1
Castro-Quintela, E1
Vila-Altesor, M1
González-Lucán, M1
Sohn, M1
Chun, EJ1
Lim, S1
Shin, WY3
Lee, HJ1
Kim, JH4
Kang, HJ2
Kim, MH2
Sung, J1
Kim, SH1
Kim, CH1
Park, JE1
Ge, J2
Oh, BH1
Dai, C1
Chen, Z1
Fu, J1
Qian, J1
Lee, CH2
Lee, JY4
Park, GM3
Lee, SW7
Kim, HS6
Choi, YJ2
Nam, CW2
Cho, JH1
Seo, JB1
Choi, SW4
Lee, JH5
Min, PK1
Her, SH1
Lee, PH1
Ahn, JM3
Park, DW6
Kang, SJ5
Kim, YH7
Lee, CW7
Park, SW7
Park, SJ7
Zhuo, X1
Zhuo, B1
Ouyang, S1
Niu, P1
Xiao, M1
Chen, YC1
Lin, FY1
Lin, YW1
Cheng, SM1
Chang, CC1
Lin, RH1
Chuang, CL1
Sheu, JS1
Chen, SM1
Tsai, CS1
Panchal, HB1
Shah, T1
Patel, P1
Albalbissi, K1
Molnar, J1
Coffey, B1
Khosla, S1
Ramu, V1
Han, S2
Cho, YR2
Lee, WS2
Jang, JY2
Kwon, CH2
Kim, WJ3
Kim, JJ2
Park, KW1
Kang, SH1
Park, JJ1
Yang, HM1
Koo, BK1
Park, BE1
Cha, KS1
Rhew, JY1
Jeon, HK1
Shin, ES2
Oh, JH2
Jeong, MH2
Kim, S1
Hwang, KK1
Yoon, JH1
Lee, SY1
Park, TH1
Moon, KW1
Kwon, HM2
Chae, IH2
Lavie, CJ1
DiNicolantonio, JJ1
Park, YK1
Ha, SJ1
Kim, SJ1
Hwang, SJ1
Woo, JS2
Kim, W2
Kim, WS2
Kim, KS1
Kim, MK2
Youn, YJ1
Lee, JW1
Ahn, SG1
Lee, SH4
Choi, H1
Yu, CW1
Hong, YJ1
Hong, MK3
Jang, Y3
Yoon, J1
Song, PS1
Song, YB1
Yang, JH1
Hahn, JY1
Choi, SH3
Choi, JH1
Seung, KB3
Gwon, HC1
Ko, YG3
Chol Kang, W1
Kwon Lee, B1
Wook Kim, S1
Shim, WH2
Kwon, BJ1
Kim, DB1
Park, HJ2
Jang, SW1
Ihm, SH1
Kim, HY1
Bundhun, PK1
Qin, T1
Chen, MH1
Mori, H1
Maeda, A1
Wakabayashi, K1
Sato, T1
Sasai, M1
Tashiro, K1
Iso, Y1
Ebato, M1
Suzuki, H1
de Donato, G1
Setacci, F1
Mele, M1
Giannace, G1
Galzerano, G1
Setacci, C1
Zuliani Mauro, MF1
Mangione, JA1
Costa, JR1
Costa, R1
Piva E Mattos, LA1
Staico, R1
Feres, F1
Siqueira, D1
Sousa, A1
Abizaid, A1
Angiolillo, DJ2
Capranzano, P2
Goto, S1
Aslam, M1
Desai, B2
Charlton, RK1
Suzuki, Y1
Box, LC1
Shoemaker, SB1
Zenni, MM1
Guzman, LA1
Bass, TA1
Grove, EL1
Kristensen, SD1
Lee, JM1
Park, S1
Shin, DJ1
Choi, D1
Shim, CY1
Kim, JS1
Chang, CW1
Lee, JE1
Chen, JJ1
Lin, LY1
Liau, CS1
Woo, KS1
Kim, BR1
Kim, JE1
Goh, RY1
Yu, LH1
Han, JY1
Kim, BK1
Lee, BK2
Kang, WC2
Kim, SW1
Lee, M1
Honda, Y1
Fitzerald, PJ1
Kim, PJ1
Yun, SC3
Seong, IW3
Lee, NH3
Cho, YH3
Lee, SJ1
Hyon, MS1
Bang, DW1
Lee, K1
Park, HK1
Park, CB1
Lee, SG1
Park, KH1
Park, WJ1
Lee, SR1
Jung, KH1
Lew, JH1
Lee, TW1
Lim, CK1
Ferreiro, JL1
Ueno, M1
Capodanno, D1
Dharmashankar, K1
Darlington, A1
Tello-Montoliu, A1
Rollini, F1
Wang, P1
Zhou, S1
Zhou, R1
Liu, G1
Tang, P1
He, J1
Ma, C1
He, Y1
Yang, J1
Bertelli, L1
Amato, A1
Sangiorgi, GM1
Belardi, JA1
Albertal, M1
Tsuchikane, E2
Kobayashi, T3
Takeda, Y2
Otsuji, S1
Sakurai, M1
Awata, N2
Nasu, K1
Inoue, T1
Uchida, T1
Sakuma, M1
Imoto, Y1
Ozeki, Y1
Ozaki, Y1
Hikichi, Y1
Node, K1
Conti, CR1
Ujiie, Y1
Hirosaka, A1
Mitsugi, M1
Ohwada, T1
Igarashi, M1
Kijima, M1
Komatsu, N1
Hisa, S1
Abe, Y1
Tsuda, T1
Yaoita, H1
Maehara, K1
Maruyama, Y1
Douglas, JS1
Ko, JK2
Park, JH2
Chun, KJ2
Ahn, Y1
Jeong, JW1
Kim, KH1
Ahn, TH1
Park, CG1
Hur, SH1
Bae, JH1
Kim, KY1
Oh, SK1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT02101437]175 participants (Actual)Interventional2014-01-31Completed
Comparison of the Efficacy and Safety of New Platform Everolimus-eluting Coronary Stent System (Promus Element) With Zotarolimus-eluting Coronary Stent System (Endeavor Resolute) and Triple Anti-platelet Therapy With Double-dose Clopidogrel Anti-platelet [NCT01267734]Phase 43,750 participants (Anticipated)Interventional2010-06-30Recruiting
A Trial of Evaluating Additional Benefit of Cilostazol to Dual Antiplatelet Therapy in Patients With Long or Multi-vessel Coronary Artery Disease Underwent Biolimus-Eluting Stent Implantation[NCT01192724]Phase 4630 participants (Actual)Interventional2010-03-31Completed
Comparison of Platelet Inhibitory Effect With Adjunctive Cilostazol Versus High Maintenance-dose ClopidogrEL in Acute Myocardial Infarction Patients According to CYP2C19 Polymorphism[NCT00915733]Phase 480 participants (Actual)Interventional2009-05-31Completed
[NCT01031667]Phase 4118 participants (Actual)Interventional2009-11-30Completed
Comparison of Triple Versus Dual Antiplatelet Therapy After ABT578-Eluting Stent Implantation For Long Coronary Lesions[NCT00589927]Phase 4486 participants (Anticipated)Interventional2007-12-31Completed
Platelet Reactivity in Patients With Chronic Kidney Disease Receiving Adjunctive Cilostazol Compared to a High-maintenance Dose of Clopidogrel[NCT01328470]Phase 485 participants (Actual)Interventional2009-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

miRNA

"miRNA-365-3p measure by Roche miRNA kits; PRP(platelet riched plasma) isolated miRNA by isolation Kit, then havest in cDNA synthesis Kit; then perform RT PCR.~." (NCT02101437)
Timeframe: 7 days

Interventionfold of change (Mean)
Control-8.14
Clopidogrel-3.46
Ticagrelor-7.54
Clopidogrel+Cilostazol-3.97

Reviews

8 reviews available for cilostazol and Coronary Artery Disease

ArticleYear
Update on Cilostazol: A Critical Review of Its Antithrombotic and Cardiovascular Actions and Its Clinical Applications.
    Journal of clinical pharmacology, 2022, Volume: 62, Issue:3

    Topics: Animals; Cilostazol; Coronary Artery Disease; Diabetes Mellitus, Type 2; Drug Therapy, Combination;

2022
Adverse clinical outcomes associated with double dose clopidogrel compared to the other antiplatelet regimens in patients with coronary artery disease: a systematic review and meta-analysis.
    BMC pharmacology & toxicology, 2018, Sep-03, Volume: 19, Issue:1

    Topics: Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Humans; Observational Studies as Topic; P

2018
Comparison of on-treatment platelet reactivity between triple antiplatelet therapy with cilostazol and standard dual antiplatelet therapy in patients undergoing coronary interventions: a meta-analysis.
    Journal of cardiovascular pharmacology and therapeutics, 2013, Volume: 18, Issue:6

    Topics: Aspirin; Blood Platelets; Cilostazol; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combinatio

2013
Comparing the effectiveness and safety between triple antiplatelet therapy and dual antiplatelet therapy in type 2 diabetes mellitus patients after coronary stents implantation: a systematic review and meta-analysis of randomized controlled trials.
    BMC cardiovascular disorders, 2015, Oct-09, Volume: 15

    Topics: Acute Coronary Syndrome; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Diabetes Mellitu

2015
Restenosis after Coronary and Peripheral Intervention: Efficacy and Clinical Impact of Cilostazol.
    Annals of vascular surgery, 2017, Volume: 41

    Topics: Cardiovascular Agents; Cilostazol; Coronary Artery Disease; Coronary Restenosis; Endovascular Proced

2017
Update on oral antiplatelet therapy: principles, problems and promises.
    Future cardiology, 2009, Volume: 5, Issue:3

    Topics: Adenosine; Administration, Oral; Cardiovascular Diseases; Cilostazol; Coronary Artery Disease; Coron

2009
The effectiveness and safety of triple-antiplatelet treatment based on cilostazol for patients receiving percutaneous coronary intervention: a meta-analysis.
    Clinical cardiology, 2012, Volume: 35, Issue:10

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Confidence Intervals; Coronary Art

2012
Pharmacologic approaches to restenosis prevention.
    The American journal of cardiology, 2007, Sep-03, Volume: 100, Issue:5A

    Topics: Angioplasty, Balloon, Coronary; Cilostazol; Coated Materials, Biocompatible; Coronary Artery Disease

2007

Trials

26 trials available for cilostazol and Coronary Artery Disease

ArticleYear
Cilostazol treatment for preventing adverse cardiovascular events in patients with type 2 diabetes and coronary atherosclerosis: Long-term follow-up of the ESCAPE study.
    Journal of diabetes, 2022, Volume: 14, Issue:8

    Topics: Aspirin; Cilostazol; Coronary Artery Disease; Coronary Stenosis; Diabetes Mellitus, Type 2; Drug The

2022
Effect of Probucol and/or Cilostazol on Carotid Intima Media Thickness in Patients with Coronary Heart Disease: A Randomized, Multicenter, Multinational Study.
    Journal of atherosclerosis and thrombosis, 2021, Feb-01, Volume: 28, Issue:2

    Topics: Anticholesteremic Agents; Carotid Intima-Media Thickness; Cholesterol, HDL; Cholesterol, LDL; Cilost

2021
Comparison of 1-Year Outcomes of Triple (Aspirin + Clopidogrel + Cilostazol) Versus Dual Antiplatelet Therapy (Aspirin + Clopidogrel + Placebo) After Implantation of Second-Generation Drug-Eluting Stents into One or More Coronary Arteries: from the DECREA
    The American journal of cardiology, 2018, 02-15, Volume: 121, Issue:4

    Topics: Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Double-Blind Method

2018
Platelet MicroRNA 365-3p Expression Correlates with High On-treatment Platelet Reactivity in Coronary Artery Disease Patients.
    Cardiovascular drugs and therapy, 2019, Volume: 33, Issue:2

    Topics: Aged; Aspirin; Blood Platelets; Cilostazol; Clopidogrel; Coronary Artery Disease; Drug Resistance; D

2019
Differential impact of cilostazol on restenosis according to implanted stent type (from a pooled analysis of three DECLARE randomized trials).
    The American journal of cardiology, 2013, Nov-01, Volume: 112, Issue:9

    Topics: Cilostazol; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Dose-Response Relati

2013
Adjunctive cilostazol versus double-dose clopidogrel after drug-eluting stent implantation: the HOST-ASSURE randomized trial (Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis-Safety & Effectiveness of Drug-Eluting Stents & Anti-plate
    JACC. Cardiovascular interventions, 2013, Volume: 6, Issue:9

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy,

2013
Comparison of dual versus triple antiplatelet therapy after drug-eluting stent according to stent length (from the pooled analysis of DECLARE trials).
    The American journal of cardiology, 2013, Dec-01, Volume: 112, Issue:11

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Diabetes Compl

2013
Effect of cilostazol addition or clopidogrel doubling on platelet function profiles in diabetic patients undergoing a percutaneous coronary intervention.
    Coronary artery disease, 2013, Volume: 24, Issue:8

    Topics: Blood Platelets; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Cross-Over

2013
Multicenter randomized trial of 3-month cilostazol use in addition to dual antiplatelet therapy after biolimus-eluting stent implantation for long or multivessel coronary artery disease.
    American heart journal, 2014, Volume: 167, Issue:2

    Topics: Aged; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; D

2014
Effects of combination therapy with cilostazol and probucol versus monotherapy with cilostazol on coronary plaque, lipid and biomarkers: SECURE study, a double-blind randomized controlled clinical trial.
    Journal of atherosclerosis and thrombosis, 2014, Volume: 21, Issue:8

    Topics: Anticholesteremic Agents; Biomarkers; Bronchodilator Agents; Cilostazol; Coronary Artery Disease; Do

2014
A randomized comparison study assessing the impact of cilostazol on the heart rate and arrhythmias by 24-hour ambulatory holter electrocardiographic monitoring after drug-eluting stent implantation for coronary artery disease.
    Journal of atherosclerosis and thrombosis, 2015, Volume: 22, Issue:2

    Topics: Arrhythmias, Cardiac; Cilostazol; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting S

2015
The Effect of Cilostazol on Endothelial Function as Assessed by Flow-Mediated Dilation in Patients with Coronary Artery Disease.
    Journal of atherosclerosis and thrombosis, 2016, Oct-01, Volume: 23, Issue:10

    Topics: Aged; Bronchodilator Agents; Cilostazol; Coronary Angiography; Coronary Artery Disease; Dilatation;

2016
Randomized Angiographic and Intravascular Ultrasound Comparison of Dual-Antiplatelet Therapy vs Triple-Antiplatelet Therapy to Reduce Neointimal Tissue Proliferation in Diabetic Patients.
    The Journal of invasive cardiology, 2017, Volume: 29, Issue:3

    Topics: Aspirin; Cilostazol; Clopidogrel; Comorbidity; Coronary Angiography; Coronary Artery Disease; Corona

2017
A randomized study assessing the impact of cilostazol on platelet function profiles in patients with diabetes mellitus and coronary artery disease on dual antiplatelet therapy: results of the OPTIMUS-2 study.
    European heart journal, 2008, Volume: 29, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Cross-Ove

2008
Relation of genetic polymorphisms in the cytochrome P450 gene with clopidogrel resistance after drug-eluting stent implantation in Koreans.
    The American journal of cardiology, 2009, Jul-01, Volume: 104, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Cilostazol; Clopidogrel; Confidence I

2009
Study design and rationale of "Synergistic effect of combination therapy with cilostazol and ProbUcol on plaque stabilization and lesion REgression (SECURE)" study: a double-blind randomised controlled multicenter clinical trial.
    Trials, 2011, Jan-12, Volume: 12

    Topics: Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Biomarkers; Cilostazol; Coronary Angiograp

2011
Comparison of dual drug-eluting Cilotax stent and paclitaxel-eluting Taxus Liberte stent in native coronary artery lesions.
    The American journal of cardiology, 2011, Apr-01, Volume: 107, Issue:7

    Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Antineoplastic Agents, Phytogenic; Cilostazol; Coronary

2011
A randomized, double-blind, multicenter comparison study of triple antiplatelet therapy with dual antiplatelet therapy to reduce restenosis after drug-eluting stent implantation in long coronary lesions: results from the DECLARE-LONG II (Drug-Eluting Sten
    Journal of the American College of Cardiology, 2011, Mar-15, Volume: 57, Issue:11

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Double-Blind M

2011
Platelet reactivity in patients with chronic kidney disease receiving adjunctive cilostazol compared with a high-maintenance dose of clopidogrel: results of the effect of platelet inhibition according to clopidogrel dose in patients with chronic kidney di
    American heart journal, 2011, Volume: 162, Issue:6

    Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Chronic Disease; Cilostazol; Clopidogrel; Coronary Arte

2011
Pharmacodynamic effects of adjunctive cilostazol therapy in patients with coronary artery disease on dual antiplatelet therapy: impact of high on-treatment platelet reactivity and diabetes mellitus status.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2013, Jan-01, Volume: 81, Issue:1

    Topics: Aged; Aspirin; Blood Platelets; Cilostazol; Clopidogrel; Coronary Artery Disease; Cross-Over Studies

2013
Balloon angioplasty plus cilostazol administration versus primary stenting of small coronary artery disease: final results of COMPASS.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2004, Volume: 63, Issue:1

    Topics: Aged; Angioplasty, Balloon; Blood Vessel Prosthesis Implantation; Cilostazol; Combined Modality Ther

2004
Cilostazol inhibits leukocyte integrin Mac-1, leading to a potential reduction in restenosis after coronary stent implantation.
    Journal of the American College of Cardiology, 2004, Oct-06, Volume: 44, Issue:7

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aged; Cilostazol; Coronary Angiography; Coronary Artery Disease

2004
Effects of angiotensin-converting enzyme inhibitors or an angiotensin receptor blocker in combination with aspirin and cilostazol on in-stent restenosis.
    International heart journal, 2006, Volume: 47, Issue:2

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists;

2006
Comparison of triple versus dual antiplatelet therapy after drug-eluting stent implantation (from the DECLARE-Long trial).
    The American journal of cardiology, 2007, Oct-01, Volume: 100, Issue:7

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Vess

2007
Randomized comparison of cilostazol vs clopidogrel after drug-eluting stenting in diabetic patients--clilostazol for diabetic patients in drug-eluting stent (CIDES) trial.
    Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:1

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Rest

2008
Drug-eluting stenting followed by cilostazol treatment reduces late restenosis in patients with diabetes mellitus the DECLARE-DIABETES Trial (A Randomized Comparison of Triple Antiplatelet Therapy with Dual Antiplatelet Therapy After Drug-Eluting Stent Im
    Journal of the American College of Cardiology, 2008, Mar-25, Volume: 51, Issue:12

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Rest

2008

Other Studies

11 other studies available for cilostazol and Coronary Artery Disease

ArticleYear
Cardiovascular Protection Associated With Cilostazol, Colchicine, and Target of Rapamycin Inhibitors.
    Journal of cardiovascular pharmacology, 2022, 07-01, Volume: 80, Issue:1

    Topics: Cilostazol; Colchicine; Coronary Artery Disease; Cyclic AMP; Diabetes Mellitus, Type 2; Humans; Musc

2022
Real-World Safety and Effectiveness of Controlled-Release Cilostazol in Patients with Symptomatic Peripheral Artery Disease.
    Clinical drug investigation, 2023, Volume: 43, Issue:9

    Topics: Cilostazol; Coronary Artery Disease; Delayed-Action Preparations; Drug-Related Side Effects and Adve

2023
Cilostazol for Chinese Patients with Aspirin Intolerance after Coronary Drug-Eluting Stent Implantation.
    Thrombosis and haemostasis, 2020, Volume: 120, Issue:5

    Topics: Aspirin; China; Cilostazol; Coronary Artery Disease; Drug-Eluting Stents; Dual Anti-Platelet Therapy

2020
Cilostazol--a forgotten antiplatelet agent, but does it even matter?
    JACC. Cardiovascular interventions, 2013, Volume: 6, Issue:9

    Topics: Cilostazol; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Male; Percuta

2013
Triple versus dual antiplatelet therapy after percutaneous coronary intervention for coronary bifurcation lesions: results from the COBIS (COronary BIfurcation Stent) II Registry.
    Heart and vessels, 2015, Volume: 30, Issue:4

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Therapy,

2015
Determinants of lower extremity amputation or revascularization procedure in patients with peripheral artery diseases: a population-based investigation.
    Angiology, 2011, Volume: 62, Issue:4

    Topics: Aged; Amputation, Surgical; Cilostazol; Coronary Artery Disease; Female; Humans; Hypertension; Logis

2011
Determination of the prevalence of aspirin and clopidogrel resistances in patients with coronary artery disease by using various platelet-function tests.
    The Korean journal of laboratory medicine, 2010, Volume: 30, Issue:5

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Drug Resistance; Drug Therapy, Comb

2010
Treatment of superficial and profunda femoral artery bifurcation lesions: still a procedure only for surgeons?
    Minerva cardioangiologica, 2012, Volume: 60, Issue:4

    Topics: Aged; Atherosclerosis; Catheters; Chronic Disease; Cilostazol; Coronary Artery Bypass; Coronary Arte

2012
Triple antiplatelet therapy with cilostazol: hitting the "sweet-spot".
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2013, Jan-01, Volume: 81, Issue:1

    Topics: Aspirin; Blood Platelets; Cilostazol; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Te

2013
Debulking and stenting versus debulking only of coronary artery disease in patients treated with cilostazol (final results of ESPRIT).
    The American journal of cardiology, 2002, Sep-15, Volume: 90, Issue:6

    Topics: Aged; Atherectomy, Coronary; Blood Vessel Prosthesis Implantation; Cilostazol; Combined Modality The

2002
Not just another restenosis trial.
    Clinical cardiology, 2004, Volume: 27, Issue:10

    Topics: Angioplasty, Balloon, Coronary; Cilostazol; Combined Modality Therapy; Coronary Artery Disease; Coro

2004