Page last updated: 2024-10-25

cilostazol and Blood Clot

cilostazol has been researched along with Blood Clot in 56 studies

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to assess the degree of platelet inhibition by adjunctive cilostazol in patients with acute myocardial infarction (AMI) according to hepatic cytochrome P450 2C19 (CYP2C19) genotype."9.15Platelet inhibition by adjunctive cilostazol versus high maintenance-dose clopidogrel in patients with acute myocardial infarction according to cytochrome P450 2C19 genotype. ( Hwang, JY; Hwang, SJ; Jeong, YH; Kim, IS; Kim, S; Koh, EH; Kwak, CH; Park, JR; Park, KS; Park, Y; Yun, SE, 2011)
"We compared the effects of ticlopidine and cilostazol on the prevention of subacute stent thrombosis (SAT) in acute myocardial infarction (AMI) patients with stenting."9.11Comparative inhibitory effects of cilostazol and ticlopidine on subacute stent thrombosis and platelet function in acute myocardial infarction patients with percutaneous coronary intervention. ( Adachi, K; Kataoka, T; Kawata, M; Kuramoto, E; Matsuura, A; Saito, A; Sakamoto, S, 2005)
"In this analysis, we aimed to systematically compare stent thrombosis (ST) and its different subtypes following treatment with DAPT (aspirin + clopidogrel) versus TAPT (aspirin + clopidogrel + cilostazol)."8.98Stent thrombosis associated with drug eluting stents on addition of cilostazol to the standard dual antiplatelet therapy following percutaneous coronary intervention: a systematic review and meta-analysis of published randomized controlled trials. ( Huang, F, 2018)
"We conducted a prospective study on patients with cerebral infarction who were treated with cilostazol."7.88Association of platelet response to cilostazol with clinical outcome and CYP genotype in patients with cerebral infarction. ( Hato, T; Ikeda, Y; Kumon, Y; Yamanouchi, J; Yasukawa, M, 2018)
"We evaluate the anti-platelet and anti-thrombotic effects of cilostazol using Multiplate® and PFA-100® in vitro and ex vivo with freshly isolated rat whole blood and in vivo venous and arterial thrombosis models in the same species, in an effort to assess the sensitivity of the whole blood aggregometer assays without potential issues of species differences."7.77Evaluation of anti-platelet and anti-thrombotic effects of cilostazol with PFA-100® and Multiplate® whole blood aggregometer in vitro, ex vivo and FeCl3-induced thrombosis models in vivo. ( Bae, IH; Chung, JH; Jeong, YS; Kim, CW; Lim, KM; Park, JW; Park, YH; Yun, JW, 2011)
"These platelets enhance thrombus formation at the sites of endothelial disruption."6.43Cilostazol: potential mechanism of action for antithrombotic effects accompanied by a low rate of bleeding. ( Goto, S, 2005)
"Z-335 (0."5.31Z-335, a new thromboxane A(2) receptor antagonist, prevents arterial thrombosis induced by ferric chloride in rats. ( Kurimoto, T; Sato, R; Tanaka, T, 2000)
"The aim of this study was to assess the degree of platelet inhibition by adjunctive cilostazol in patients with acute myocardial infarction (AMI) according to hepatic cytochrome P450 2C19 (CYP2C19) genotype."5.15Platelet inhibition by adjunctive cilostazol versus high maintenance-dose clopidogrel in patients with acute myocardial infarction according to cytochrome P450 2C19 genotype. ( Hwang, JY; Hwang, SJ; Jeong, YH; Kim, IS; Kim, S; Koh, EH; Kwak, CH; Park, JR; Park, KS; Park, Y; Yun, SE, 2011)
"We compared the effects of ticlopidine and cilostazol on the prevention of subacute stent thrombosis (SAT) in acute myocardial infarction (AMI) patients with stenting."5.11Comparative inhibitory effects of cilostazol and ticlopidine on subacute stent thrombosis and platelet function in acute myocardial infarction patients with percutaneous coronary intervention. ( Adachi, K; Kataoka, T; Kawata, M; Kuramoto, E; Matsuura, A; Saito, A; Sakamoto, S, 2005)
"In this analysis, we aimed to systematically compare stent thrombosis (ST) and its different subtypes following treatment with DAPT (aspirin + clopidogrel) versus TAPT (aspirin + clopidogrel + cilostazol)."4.98Stent thrombosis associated with drug eluting stents on addition of cilostazol to the standard dual antiplatelet therapy following percutaneous coronary intervention: a systematic review and meta-analysis of published randomized controlled trials. ( Huang, F, 2018)
" In the last few years, cilostazol, a phosphodiesterase (PDE) 3 inhibitor, has been tested in the setting of acute coronary syndromes: it exerts not only anti-platelet actions, but also pleiotropic effects, including inhibition on neointimal hyperplasia, therefore preventing both stent restenosis and thrombosis."4.88Cilostazol and primary-PCI: mirage or good alternative? ( Crea, F; D'Amario, D; Porto, I, 2012)
" We give an overview of several new antiplatelet agents that are currently investigated in secondary stroke prevention: adenosine 5'-diphosphonate receptor antagonists, cilostazol, sarpogrelate, terutroban and SCH 530348."4.86Controversies and future perspectives of antiplatelet therapy in secondary stroke prevention. ( Diener, HC; Weber, R, 2010)
"Patients on cilostazol were divided into 4 groups according to arterial occlusive disease etiology: (1) atherosclerosis, (2) diabetic angiopathy, (3) embolism/thrombosis, and (4) Buerger disease."4.31Do Patients With Arterial Occlusive Disease of Different Etiologies Benefit Equally From Cilostazol? ( Arslan, K; Can Depboylu, B; Funda Tetik, M; Harmandar, B; Ilhan, G; Istar, H; Yazman, S, 2023)
"We conducted a prospective study on patients with cerebral infarction who were treated with cilostazol."3.88Association of platelet response to cilostazol with clinical outcome and CYP genotype in patients with cerebral infarction. ( Hato, T; Ikeda, Y; Kumon, Y; Yamanouchi, J; Yasukawa, M, 2018)
"Cilostazol was associated with a significant reduction in late loss in BMS (mean difference 0."3.84Efficacy of cilostazol in reducing restenosis in patients undergoing contemporary stent based PCI: a meta-analysis of randomised controlled trials. ( Chen, KY; Chetcuti, S; Grossman, MP; Gurm, H; Meier, P; Rha, SW; Tamhane, U, 2009)
"We evaluate the anti-platelet and anti-thrombotic effects of cilostazol using Multiplate® and PFA-100® in vitro and ex vivo with freshly isolated rat whole blood and in vivo venous and arterial thrombosis models in the same species, in an effort to assess the sensitivity of the whole blood aggregometer assays without potential issues of species differences."3.77Evaluation of anti-platelet and anti-thrombotic effects of cilostazol with PFA-100® and Multiplate® whole blood aggregometer in vitro, ex vivo and FeCl3-induced thrombosis models in vivo. ( Bae, IH; Chung, JH; Jeong, YS; Kim, CW; Lim, KM; Park, JW; Park, YH; Yun, JW, 2011)
"One possible cause of stent thrombosis is an insufficient effect of clopidogrel."3.77Optimizing of thienopyridine therapy by multiple electrode platelet aggregometry in clopidogrel low responders undergoing PCI. ( Behr, T; Behr, W; Kuch, B; von Scheidt, W, 2011)
"The purpose of this study was to investigate the efficacy of cilostazol for prevention of thrombosis in microsurgical anastomosis."3.76Cilostazol effectively reduces the decrease of flow volume in a thrombotic anastomosis model in a rat: a novel application of ultrasonography for evaluation. ( Chang, HW; Choi, TH; Han, K; Kim, JH; Kim, SH; Lee, SY; Park, J; Park, SH; Son, D; Suh, EH, 2010)
"These results suggest that oral administration of cilostazol is an effective method of preventing thrombotic occlusion and intimal hyperplasia after stenting."3.69Pharmacologic treatment of intimal hyperplasia after metallic stent placement in the peripheral arteries. An experimental study. ( Kichikawa, K; Kimura, Y; Kubota, Y; Maeda, M; Makutani, S; Nishimine, K; Ohishi, H; Sakaguchi, S; Uchida, H; Yoshioka, T, 1995)
" Pharmacokinetics and pharmacodynamic (antithrombotic) efficacy were evaluated in beagle dog model of arterial thrombosis."2.79Preparation and evaluation of oral controlled-release cilostazol formulation: pharmacokinetics and antithrombotic efficacy in dogs and healthy male Korean participants. ( Park, JW; Shin, KH; Yoon, G; Yoon, IS, 2014)
" Major adverse cardiovascular events, stent thrombosis, target lesion revascularization (TLR), target vessel revascularization, and bleeding events were analyzed after 1-year follow-up."2.78Efficacy and safety of triple antiplatelet therapy in obese patients undergoing stent implantation. ( Gao, W; Ge, H; Guo, Y; Zhang, Q; Zhou, Z, 2013)
" Cilostazol-based TAPT compared with DAPT is associated with improved angiographic outcomes and decreased risk of TLR and TVR but does not reduce major cardiovascular events and is associated with an increase in minor adverse events."2.52Efficacy and safety of cilostazol based triple antiplatelet treatment versus dual antiplatelet treatment in patients undergoing coronary stent implantation: an updated meta-analysis of the randomized controlled trials. ( Bai, J; Chen, J; Chen, P; Eikelboom, JW; Gong, X; Kong, D; Li, C; Liu, J; Meng, H; Xu, L; Yang, Z; Zou, F, 2015)
"Since antiplatelet therapy in type 2 diabetes mellitus (T2DM) patients is very important after intracoronary stenting, and because the most commonly used therapies have been the dual antiplatelet therapy (DAPT) consisting of aspirin and clopidogrel and the triple antiplatelet therapy (TAPT) consisting of aspirin, clopidogrel and cilostazol, we aim to compare the effectiveness and safety between triple antiplatelet therapy and dual antiplatelet therapy in T2DM patients."2.52Comparing the effectiveness and safety between triple antiplatelet therapy and dual antiplatelet therapy in type 2 diabetes mellitus patients after coronary stents implantation: a systematic review and meta-analysis of randomized controlled trials. ( Bundhun, PK; Chen, MH; Qin, T, 2015)
"In the peripheral arteries, a thrombus superimposed on atherosclerosis contributes to the progression of peripheral artery disease (PAD), producing intermittent claudication (IC), ischemic necrosis, and, potentially, loss of the limb."2.50Systematic reviews and meta-analyses for more profitable strategies in peripheral artery disease. ( Cafaro, G; de Gaetano, G; Di Minno, A; Di Minno, G; Lupoli, R; Petitto, M; Spadarella, G; Tremoli, E, 2014)
"These platelets enhance thrombus formation at the sites of endothelial disruption."2.43Cilostazol: potential mechanism of action for antithrombotic effects accompanied by a low rate of bleeding. ( Goto, S, 2005)
"Cilostazol effects were also shown in aspirin-treated platelets."1.48Impact of Multidrug Resistance Protein-4 Inhibitors on Modulating Platelet Function and High on-Aspirin Treatment Platelet Reactivity. ( Alemanno, L; Angiolillo, DJ; Frati, L; Guarino, ML; Klaus, V; Maltese, T; Massimi, I; Pulcinelli, FM, 2018)
"Cilostazol has potential for protecting vessels against hyperglycemic injury and for accelerating the healing process after implantation of DES."1.39Cilostazol protects vessels against hyperglycemic injury and accelerates healing after implantation of drug-eluting stent in a type 1 diabetes mellitus rat aorta stent model. ( Ahn, Y; Cho, HH; Hong, MH; Jeong, HY; Jeong, MH; Kang, WS; Kee, HJ; Kim, YS; Kwon, JS, 2013)
"Cilostazol is an anti-platelet drug that reversibly inhibits phosphodiesterase III (PDE-III), which is ubiquitously expressed in platelets and various tissues."1.38Cilostazol down-regulates the height of mural platelet thrombi formed under a high-shear rate flow in the absence of ADAMTS13 activity. ( Fujimura, Y; Hayakawa, M; Matsumoto, M; Shida, Y; Sugimoto, M; Tsubaki, K; Wada, H; Yagi, H; Yamaguchi, N, 2012)
"Cilostazol has reduced restenosis and repeat intervention after drug-eluting stent (DES) implantation."1.36Triple antiplatelet therapy reduces ischemic events after drug-eluting stent implantation: Drug-Eluting stenting followed by Cilostazol treatment REduces Adverse Serious cardiac Events (DECREASE registry). ( Hong, MK; Kim, JJ; Kim, WJ; Kim, YH; Lee, CW; Lee, JY; Lee, SW; Park, DW; Park, SJ; Park, SW; Yun, SC, 2010)
"Ratios of red thrombus to prosthetic graft area were 0."1.35Effects of cilostazol and k-134 on reconstructive surgery using prosthetic grafts in the abdominal aorta of beagle dogs. ( Inoue, Y; Iwai, T; Jibiki, M; Kudo, T; Sugano, N, 2008)
" At 7 and 30 days, the composite outcome for the group treated with cilostazol alone and that treated with abciximab in combination with cilostazol did not differ significantly."1.34Efficacy and safety of abciximab in combination with cilostazol in patients undergoing stenting. ( Hong, EH; Kim, MY; Lee, MH; Oh, JM; Park, JE; Shin, WG, 2007)
"Z-335 (0."1.31Z-335, a new thromboxane A(2) receptor antagonist, prevents arterial thrombosis induced by ferric chloride in rats. ( Kurimoto, T; Sato, R; Tanaka, T, 2000)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.57)18.7374
1990's3 (5.36)18.2507
2000's17 (30.36)29.6817
2010's32 (57.14)24.3611
2020's2 (3.57)2.80

Authors

AuthorsStudies
Koga, Y1
Kihara, Y1
Okada, M1
Inoue, Y2
Tochizawa, S1
Toga, K1
Tachibana, K1
Kimura, Y4
Nishi, T1
Hidaka, H1
Can Depboylu, B1
Yazman, S1
Harmandar, B1
Funda Tetik, M1
Istar, H1
Arslan, K1
Ilhan, G1
Bartholomew, J1
Bishop, GJ1
Rychter, M1
Baranowska-Korczyc, A1
Milanowski, B1
Jarek, M1
Maciejewska, BM1
Coy, EL1
Lulek, J1
Alemanno, L1
Massimi, I1
Klaus, V1
Guarino, ML1
Maltese, T1
Frati, L1
Angiolillo, DJ2
Pulcinelli, FM1
Huang, F1
Ikeda, Y1
Yamanouchi, J1
Kumon, Y1
Yasukawa, M1
Hato, T1
Kwon, JS1
Kim, YS1
Cho, HH1
Kee, HJ1
Hong, MH1
Kang, WS1
Jeong, HY1
Jeong, MH1
Ahn, Y1
Shin, KH1
Yoon, G1
Yoon, IS1
Park, JW2
Chen, J1
Meng, H1
Xu, L1
Liu, J1
Kong, D1
Chen, P1
Gong, X1
Bai, J1
Zou, F1
Yang, Z1
Li, C1
Eikelboom, JW2
Di Minno, G1
Spadarella, G1
Cafaro, G1
Petitto, M1
Lupoli, R1
Di Minno, A1
de Gaetano, G1
Tremoli, E1
Bundhun, PK1
Qin, T1
Chen, MH1
Kim, JY1
Choi, YS1
Kwon, A1
Chung, WB1
Park, CS1
Kim, HY1
Chang, K1
Lee, MY1
Chung, WS1
Seung, KB1
Sugano, N1
Jibiki, M1
Kudo, T1
Iwai, T1
Arai, F1
Kita, T1
Sasaki, S1
Onoda, K1
Ohashi, K1
Hashimoto, A1
Okuda, M1
Shimono, T1
Nishikawa, M2
Shimpo, H1
Ryu, KH1
Han, HY1
Lee, SY4
Jeon, SD1
Im, GJ1
Lee, BY1
Kim, K1
Lim, KM2
Chung, JH2
Tamhane, U1
Meier, P1
Chetcuti, S1
Chen, KY1
Rha, SW1
Grossman, MP1
Gurm, H1
Yasuda, H1
Yamada, M1
Sawada, S1
Endo, Y1
Inoue, K1
Asano, F1
Takeyama, Y1
Yoshiba, M1
Lee, SW3
Park, SW3
Yun, SC1
Kim, YH3
Park, DW1
Kim, WJ1
Lee, JY1
Lee, CW3
Hong, MK3
Kim, JJ3
Park, SJ3
Croce, K1
Kim, SH2
Chang, HW1
Choi, TH1
Kim, JH2
Son, D1
Han, K1
Park, J1
Suh, EH1
Park, SH1
Weber, R1
Diener, HC1
Lin, GM1
Chu, KM1
Han, CL1
Jeong, YH3
Park, Y3
Kim, IS3
Yun, SE2
Kang, MK1
Hwang, SJ2
Kwak, CH2
Hwang, JY2
Kim, CW1
Yun, JW1
Bae, IH1
Park, YH2
Jeong, YS1
Park, KS1
Park, JR1
Koh, EH1
Kim, S1
Behr, T1
Kuch, B1
Behr, W1
von Scheidt, W1
Gresele, P1
Momi, S1
Falcinelli, E1
Bliden, KP1
Tantry, US1
Gurbel, PA1
Ferreiro, JL1
Ueno, M1
Desai, B1
Capranzano, P1
Capodanno, D1
Pant, S1
Neupane, P1
Ramesh, KC1
Barakoti, M1
Hirsh, J1
Spencer, FA1
Baglin, TP1
Weitz, JI1
Porto, I1
D'Amario, D1
Crea, F1
Sidddiqi, SA1
Kamal, AK1
Hondo, T1
Matsumura, H1
Matsuda, K1
Iwamoto, A1
Eno, S1
Kimura, M1
Ashitate, Y1
Tanaka, E1
Henary, M1
Choi, HS1
Frangioni, JV1
Flaumenhaft, R2
Yamada, K1
Niki, H1
Nagai, H1
Nakagawa, H1
Yagi, H1
Yamaguchi, N1
Shida, Y1
Hayakawa, M1
Matsumoto, M1
Sugimoto, M1
Wada, H1
Tsubaki, K1
Fujimura, Y1
Lee, GY1
Hahn, JY1
Kim, HJ1
Song, YB1
Choi, SH1
Choi, JH1
Gwon, HC1
Gao, W1
Zhang, Q1
Ge, H1
Guo, Y1
Zhou, Z1
Sim, DS1
Merrill-Skoloff, G1
Furie, BC1
Furie, B1
Ahn, JC1
Song, WH1
Kwon, JA1
Park, CG1
Seo, HS1
Oh, DJ1
Rho, YM1
Park, JH1
Kang, SJ1
Han, KH2
Kawata, M1
Kuramoto, E1
Kataoka, T1
Saito, A1
Adachi, K1
Matsuura, A1
Sakamoto, S1
Massel, D1
Goto, S2
Lee, BK1
Song, JM1
Kang, DH1
Song, JK1
Meadows, TA1
Bhatt, DL1
Hong, EH1
Kim, MY1
Park, JE1
Lee, MH1
Oh, JM1
Shin, WG1
Kubota, Y1
Kichikawa, K1
Uchida, H1
Maeda, M1
Nishimine, K1
Makutani, S1
Sakaguchi, S1
Yoshioka, T1
Ohishi, H1
Kohda, N1
Tani, T2
Nakayama, S1
Adachi, T1
Marukawa, K1
Ito, R1
Ishida, K1
Matsumoto, Y1
Tanaka, T1
Sato, R1
Kurimoto, T1
Kanbe, T1
Watanabe, K1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Platelet Inhibitory Effect With Adjunctive Cilostazol Versus High Maintenance-dose ClopidogrEL in Acute Myocardial Infarction Patients According to CYP2C19 Polymorphism[NCT00915733]Phase 480 participants (Actual)Interventional2009-05-31Completed
"Evaluation of Antiplatelet Effects and Safety of Intraoperative Administration of Ticagrelor Versus Clopidogrel in Patients Undergoing One-stop Hybrid Coronary Revascularization"[NCT02513004]Phase 460 participants (Anticipated)Interventional2015-06-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

12 reviews available for cilostazol and Blood Clot

ArticleYear
Stent thrombosis associated with drug eluting stents on addition of cilostazol to the standard dual antiplatelet therapy following percutaneous coronary intervention: a systematic review and meta-analysis of published randomized controlled trials.
    BMC pharmacology & toxicology, 2018, 06-18, Volume: 19, Issue:1

    Topics: Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Percutaneo

2018
Efficacy and safety of cilostazol based triple antiplatelet treatment versus dual antiplatelet treatment in patients undergoing coronary stent implantation: an updated meta-analysis of the randomized controlled trials.
    Journal of thrombosis and thrombolysis, 2015, Volume: 39, Issue:1

    Topics: Aspirin; Brain Ischemia; Cilostazol; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; M

2015
Systematic reviews and meta-analyses for more profitable strategies in peripheral artery disease.
    Annals of medicine, 2014, Volume: 46, Issue:7

    Topics: Adenosine; Aspirin; Asymptomatic Diseases; Cilostazol; Clopidogrel; Fibrinolytic Agents; Humans; Int

2014
Comparing the effectiveness and safety between triple antiplatelet therapy and dual antiplatelet therapy in type 2 diabetes mellitus patients after coronary stents implantation: a systematic review and meta-analysis of randomized controlled trials.
    BMC cardiovascular disorders, 2015, Oct-09, Volume: 15

    Topics: Acute Coronary Syndrome; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Diabetes Mellitu

2015
Efficacy of cilostazol in reducing restenosis in patients undergoing contemporary stent based PCI: a meta-analysis of randomised controlled trials.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2009, Volume: 5, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Coronary Angiography; Coronary Restenosis

2009
Controversies and future perspectives of antiplatelet therapy in secondary stroke prevention.
    Journal of cellular and molecular medicine, 2010, Volume: 14, Issue:10

    Topics: Aspirin; Blood-Brain Barrier; Cilostazol; Clopidogrel; Dipyridamole; Drug Interactions; Drug Therapy

2010
Anti-platelet therapy: phosphodiesterase inhibitors.
    British journal of clinical pharmacology, 2011, Volume: 72, Issue:4

    Topics: Blood Platelets; Cilostazol; Clinical Trials as Topic; Dipyridamole; Humans; Phosphodiesterase Inhib

2011
Antiplatelet drugs: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
    Chest, 2012, Volume: 141, Issue:2 Suppl

    Topics: Aspirin; Cilostazol; Dipyridamole; Dose-Response Relationship, Drug; Drug Therapy, Combination; Evid

2012
Cilostazol and primary-PCI: mirage or good alternative?
    Current vascular pharmacology, 2012, Volume: 10, Issue:4

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Arrhythmias, Cardiac; Aspirin; Cilostazol;

2012
Cilostazol: potential mechanism of action for antithrombotic effects accompanied by a low rate of bleeding.
    Atherosclerosis. Supplements, 2005, Dec-15, Volume: 6, Issue:4

    Topics: Bleeding Time; Cilostazol; Dose-Response Relationship, Drug; Hemorrhage; Humans; Platelet Aggregatio

2005
[Basic principal of the dual antithrombotic therapy achieved by cilostazol].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Oct-28, Volume: 64 Suppl 7

    Topics: Cilostazol; Hemorrhage; Humans; Phosphodiesterase Inhibitors; Tetrazoles; Thrombosis; Vasodilator Ag

2006
Clinical aspects of platelet inhibitors and thrombus formation.
    Circulation research, 2007, May-11, Volume: 100, Issue:9

    Topics: Aspirin; Atherosclerosis; Blood Platelets; Cardiovascular Diseases; Cilostazol; Clopidogrel; Dipyrid

2007

Trials

9 trials available for cilostazol and Blood Clot

ArticleYear
Preparation and evaluation of oral controlled-release cilostazol formulation: pharmacokinetics and antithrombotic efficacy in dogs and healthy male Korean participants.
    The Journal of pharmacy and pharmacology, 2014, Volume: 66, Issue:7

    Topics: Administration, Oral; Animals; Cilostazol; Delayed-Action Preparations; Disease Models, Animal; Dogs

2014
Inhibition of platelet aggregation by combined therapy with aspirin and cilostazol after off-pump coronary artery bypass surgery.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2008, Volume: 14, Issue:4

    Topics: Aged; Aspirin; Cilostazol; Coronary Artery Bypass, Off-Pump; Drug Therapy, Combination; Female; Fibr

2008
Efficacy of cilostazol in reducing restenosis in patients undergoing contemporary stent based PCI: a meta-analysis of randomised controlled trials.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2009, Volume: 5, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Coronary Angiography; Coronary Restenosis

2009
Enhanced platelet inhibition by adjunctive cilostazol to dual antiplatelet therapy after drug-eluting stent implantation for complex lesions.
    Thrombosis and haemostasis, 2010, Volume: 104, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; F

2010
Platelet inhibition by adjunctive cilostazol versus high maintenance-dose clopidogrel in patients with acute myocardial infarction according to cytochrome P450 2C19 genotype.
    JACC. Cardiovascular interventions, 2011, Volume: 4, Issue:4

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin;

2011
Adjunctive cilostazol versus high maintenance dose of clopidogrel in patients with hyporesponsiveness to chronic clopidogrel therapy.
    Yonsei medical journal, 2013, Jan-01, Volume: 54, Issue:1

    Topics: Adult; Aged; Blood Platelets; Cilostazol; Clopidogrel; Cross-Over Studies; Drug Administration Sched

2013
Efficacy and safety of triple antiplatelet therapy in obese patients undergoing stent implantation.
    Angiology, 2013, Volume: 64, Issue:7

    Topics: Adult; Aged; Aspirin; Blood Platelets; Cilostazol; Clopidogrel; Drug Therapy, Combination; Female; H

2013
Comparison of cilostazol and clopidogrel after successful coronary stenting.
    The American journal of cardiology, 2005, Apr-01, Volume: 95, Issue:7

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Coronary Restenosis; Female;

2005
Comparative inhibitory effects of cilostazol and ticlopidine on subacute stent thrombosis and platelet function in acute myocardial infarction patients with percutaneous coronary intervention.
    International heart journal, 2005, Volume: 46, Issue:1

    Topics: Aged; Aspirin; Cilostazol; Drug Therapy, Combination; Female; Humans; Incidence; Male; Myocardial In

2005

Other Studies

36 other studies available for cilostazol and Blood Clot

ArticleYear
2(1H)-quinolinone derivatives as novel anti-arteriostenotic agents showing anti-thrombotic and anti-hyperplastic activities.
    Bioorganic & medicinal chemistry letters, 1998, Jun-16, Volume: 8, Issue:12

    Topics: Animals; Arteriosclerosis; Cilostazol; Hyperplasia; Platelet Aggregation Inhibitors; Quinolines; Qui

1998
Do Patients With Arterial Occlusive Disease of Different Etiologies Benefit Equally From Cilostazol?
    Texas Heart Institute journal, 2023, 01-01, Volume: 50, Issue:1

    Topics: Atherosclerosis; Cilostazol; Diabetic Angiopathies; Humans; Peripheral Arterial Disease; Quality of

2023
New treatments for peripheral artery disease.
    Cleveland Clinic journal of medicine, 2020, Volume: 87, Issue:5 suppl 1

    Topics: Ankle Brachial Index; Anticholesteremic Agents; Cilostazol; Diet, Healthy; Dual Anti-Platelet Therap

2020
Cilostazol-Loaded Poly(ε-Caprolactone) Electrospun Drug Delivery System for Cardiovascular Applications.
    Pharmaceutical research, 2018, Jan-16, Volume: 35, Issue:2

    Topics: Atherosclerosis; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Cilostazol; Drug Com

2018
Impact of Multidrug Resistance Protein-4 Inhibitors on Modulating Platelet Function and High on-Aspirin Treatment Platelet Reactivity.
    Thrombosis and haemostasis, 2018, Volume: 118, Issue:3

    Topics: Aged; Aspirin; Blood Platelets; Cilostazol; Cohort Studies; Cyclic AMP; Female; Humans; Male; Middle

2018
Association of platelet response to cilostazol with clinical outcome and CYP genotype in patients with cerebral infarction.
    Thrombosis research, 2018, Volume: 172

    Topics: Aged; Cell Adhesion Molecules; Cerebral Infarction; Cilostazol; Cytochrome P-450 CYP2C19; Cytochrome

2018
Cilostazol protects vessels against hyperglycemic injury and accelerates healing after implantation of drug-eluting stent in a type 1 diabetes mellitus rat aorta stent model.
    Atherosclerosis, 2013, Volume: 228, Issue:2

    Topics: Administration, Oral; Angioplasty, Balloon; Animals; Aorta; Aortic Diseases; Apoptosis; Blood Glucos

2013
It Is Not Mandatory to Use Triple Rather Than Dual Anti-Platelet Therapy After a Percutaneous Coronary Intervention With a Second-Generation Drug-Eluting Stent.
    Medicine, 2015, Volume: 94, Issue:46

    Topics: Adult; Aged; Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Evero

2015
Effects of cilostazol and k-134 on reconstructive surgery using prosthetic grafts in the abdominal aorta of beagle dogs.
    Thrombosis research, 2008, Volume: 123, Issue:1

    Topics: Animals; Aorta, Abdominal; Blood Vessel Prosthesis Implantation; Cilostazol; Male; Mice; Plastic Sur

2008
[Perioperative management of patients with drug-eluting coronary stents presenting for non-cardiac surgery].
    Masui. The Japanese journal of anesthesiology, 2008, Volume: 57, Issue:7

    Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Cilostazol; Drug Administration Schedule; Drug-Elu

2008
Ginkgo biloba extract enhances antiplatelet and antithrombotic effects of cilostazol without prolongation of bleeding time.
    Thrombosis research, 2009, Volume: 124, Issue:3

    Topics: Animals; Bleeding Time; Blood Coagulation; Cells, Cultured; Cilostazol; Drug Synergism; Fibrinolytic

2009
Upper gastrointestinal bleeding in patients receiving dual antiplatelet therapy after coronary stenting.
    Internal medicine (Tokyo, Japan), 2009, Volume: 48, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Co

2009
Triple antiplatelet therapy reduces ischemic events after drug-eluting stent implantation: Drug-Eluting stenting followed by Cilostazol treatment REduces Adverse Serious cardiac Events (DECREASE registry).
    American heart journal, 2010, Volume: 159, Issue:2

    Topics: Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up

2010
Antiplatelet therapy after percutaneous coronary intervention: Should another regimen be "TAPT?".
    Circulation. Cardiovascular interventions, 2010, Feb-01, Volume: 3, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Chemotherapy, Adjuvant; Cilostazol; C

2010
Cilostazol effectively reduces the decrease of flow volume in a thrombotic anastomosis model in a rat: a novel application of ultrasonography for evaluation.
    Annals of plastic surgery, 2010, Volume: 64, Issue:4

    Topics: Anastomosis, Surgical; Animals; Cilostazol; Disease Models, Animal; Iliac Artery; Male; Microsurgery

2010
Triple antiplatelet therapy reduces ischemic events after drug-eluting stent implantation: Drug-Eluting stenting followed by Cilostazol treatment REduces Adverse Serious cardiac Events (DECREASE registry).
    American heart journal, 2010, Volume: 160, Issue:3

    Topics: Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Myocardial

2010
Evaluation of anti-platelet and anti-thrombotic effects of cilostazol with PFA-100® and Multiplate® whole blood aggregometer in vitro, ex vivo and FeCl3-induced thrombosis models in vivo.
    Thrombosis research, 2011, Volume: 127, Issue:6

    Topics: Animals; Blood Platelets; Chlorides; Cilostazol; Ferric Compounds; Fibrinolytic Agents; Male; Mice;

2011
Optimizing of thienopyridine therapy by multiple electrode platelet aggregometry in clopidogrel low responders undergoing PCI.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2011, Volume: 100, Issue:10

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Cerebrovascula

2011
We need further studies for the development of "optimized antiplatelet therapy" based on ethnicity.
    Journal of the American College of Cardiology, 2011, Jul-05, Volume: 58, Issue:2

    Topics: Administration, Oral; Alleles; Aryl Hydrocarbon Hydroxylases; Asian People; Blood Platelets; Cilosta

2011
Impact of adjunctive cilostazol therapy versus high maintenance dose of clopidogrel in suboptimal responders with diabetes mellitus.
    Revista espanola de cardiologia (English ed.), 2012, Volume: 65, Issue:1

    Topics: Aspirin; Blood Coagulation; Blood Platelets; Cilostazol; Clopidogrel; Diabetes Mellitus, Type 2; Hum

2012
Post percutaneous coronary intervention antiplatelet therapy: current perceptions, prospects and perplexity.
    Cardiology journal, 2011, Volume: 18, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Coronary Restenosis; Drug Resistan

2011
A new antiplatelet agent cilostazol--what is the evidence for its use and tolerability?
    JPMA. The Journal of the Pakistan Medical Association, 2012, Volume: 62, Issue:1

    Topics: Aspirin; Cilostazol; Evidence-Based Medicine; Humans; Platelet Aggregation Inhibitors; Randomized Co

2012
A case of acute coronary artery occlusion associated with very rapid onset heparin-induced thrombosis without thrombocytopenia.
    Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:6

    Topics: Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Aspirin; Autoantibodies

2012
Two-wavelength near-infrared fluorescence for the quantitation of drug antiplatelet effects in large animal model systems.
    Journal of vascular surgery, 2012, Volume: 56, Issue:1

    Topics: Analysis of Variance; Animals; Aspirin; Blood Platelets; Cilostazol; Disease Models, Animal; Female;

2012
Serotonin potentiates high-glucose-induced endothelial injury: the role of serotonin and 5-HT(2A) receptors in promoting thrombosis in diabetes.
    Journal of pharmacological sciences, 2012, Volume: 119, Issue:3

    Topics: Animals; Aspirin; Cells, Cultured; Cilostazol; Diabetes Mellitus, Experimental; Fibrinolytic Agents;

2012
Cilostazol down-regulates the height of mural platelet thrombi formed under a high-shear rate flow in the absence of ADAMTS13 activity.
    European journal of pharmacology, 2012, Sep-15, Volume: 691, Issue:1-3

    Topics: ADAM Proteins; ADAMTS13 Protein; Adult; Biomechanical Phenomena; Bleeding Time; Blood Platelets; Cil

2012
Initial accumulation of platelets during arterial thrombus formation in vivo is inhibited by elevation of basal cAMP levels.
    Blood, 2004, Mar-15, Volume: 103, Issue:6

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Blood Platelets; Cilostazol; Cyclic AMP; Cyclic Nucleo

2004
Effects of cilostazol on platelet activation in coronary stenting patients who already treated with aspirin and clopidogrel.
    The Korean journal of internal medicine, 2004, Volume: 19, Issue:4

    Topics: Aspirin; Cilostazol; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Femal

2004
P >0.05 not equal equivalent or noninferior.
    The American journal of cardiology, 2005, Oct-01, Volume: 96, Issue:7

    Topics: Angioplasty, Balloon, Coronary; Cilostazol; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Re

2005
Triple versus dual antiplatelet therapy after coronary stenting: impact on stent thrombosis.
    Journal of the American College of Cardiology, 2005, Nov-15, Volume: 46, Issue:10

    Topics: Aspirin; Cilostazol; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Female; Humans; Male;

2005
Efficacy and safety of abciximab in combination with cilostazol in patients undergoing stenting.
    International journal of clinical pharmacology and therapeutics, 2007, Volume: 45, Issue:6

    Topics: Abciximab; Aged; Angina, Unstable; Antibodies, Monoclonal; Cilostazol; Coronary Angiography; Coronar

2007
Pharmacologic treatment of intimal hyperplasia after metallic stent placement in the peripheral arteries. An experimental study.
    Investigative radiology, 1995, Volume: 30, Issue:9

    Topics: Administration, Oral; Animals; Arterial Occlusive Diseases; Cilostazol; Dogs; Embolization, Therapeu

1995
Effect of cilostazol, a phosphodiesterase III inhibitor, on experimental thrombosis in the porcine carotid artery.
    Thrombosis research, 1999, Nov-15, Volume: 96, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Carotid Arteries; Cilostazol; Cyclic Nucleotide Phosph

1999
Z-335, a new thromboxane A(2) receptor antagonist, prevents arterial thrombosis induced by ferric chloride in rats.
    European journal of pharmacology, 2000, Aug-11, Volume: 401, Issue:3

    Topics: Administration, Oral; Animals; Aorta, Abdominal; Chlorides; Cilostazol; Dose-Response Relationship,

2000
New antithrombotic agent, cilostazol.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:7A

    Topics: Animals; Azoles; Cilostazol; Fibrinolytic Agents; Humans; Tetrazoles; Thrombosis; Vasodilator Agents

1985
Effect of cilostazol on platelet aggregation and experimental thrombosis.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:7A

    Topics: Adenosine Diphosphate; Animals; Aspirin; Azoles; Cilostazol; Dogs; Fibrinolytic Agents; Humans; In V

1985