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cilostazol and Acute Coronary Syndrome

cilostazol has been researched along with Acute Coronary Syndrome in 13 studies

Acute Coronary Syndrome: An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
" We investigated the effects of cilostazol 200 mg, in addition to aspirin 100 mg and clopidogrel 75 mg, on carotid intima-media thickness (IMT) progression during a 2-year follow-up period in patients with acute coronary syndrome (ACS) requiring stent implantation."9.15Cilostazol reduces the progression of carotid intima-media thickness without increasing the risk of bleeding in patients with acute coronary syndrome during a 2-year follow-up. ( Ahn, CM; Hong, SJ; Kim, JS; Lim, DS; Park, JH, 2011)
"In this prospective study, 1,212 patients with acute coronary syndromes were randomly assigned to receive either standard dual-antiplatelet treatment with aspirin and clopidogrel (n = 608) or triple-antiplatelet therapy with the addition of a 6-month course of cilostazol (n = 604) after successful PCI."9.14Cilostazol in addition to aspirin and clopidogrel improves long-term outcomes after percutaneous coronary intervention in patients with acute coronary syndromes: a randomized, controlled study. ( Han, Y; Jing, Q; Li, Y; Shu, Q; Tang, X; Wang, D; Wang, S; Wang, Z, 2009)
"Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor antagonist is the standard of care in acute coronary syndromes."8.89Triple versus dual antiplatelet therapy in acute coronary syndromes: adding cilostazol to aspirin and clopidogrel? ( Bangalore, S; Dinicolantonio, JJ; Lavie, CJ; Meier, P; Niazi, AK; O'Keefe, JH, 2013)
"Cilostazol 100 mg b."6.75Effect of cilostazol on platelet aggregation in patients with non-ST elevation acute coronary syndrome. ( Ahluwalia, J; Bhalla, A; Malhotra, S; Pandhi, P; Pattanaik, S; Sharma, YP, 2010)
"Cilostazol is a specific and strong inhibitor of phosphodiesterase (PDE) type III which can suppress the platelet aggregation by increasing cyclic adenosine monophosphate (cAMP) levels."5.62Cilostazol increases adenosine plasma concentration in patients with acute coronary syndrome. ( Chen, J; Li, X; Lv, Q; Wang, Z; Wu, H; Xue, Y, 2021)
" We investigated the effects of cilostazol 200 mg, in addition to aspirin 100 mg and clopidogrel 75 mg, on carotid intima-media thickness (IMT) progression during a 2-year follow-up period in patients with acute coronary syndrome (ACS) requiring stent implantation."5.15Cilostazol reduces the progression of carotid intima-media thickness without increasing the risk of bleeding in patients with acute coronary syndrome during a 2-year follow-up. ( Ahn, CM; Hong, SJ; Kim, JS; Lim, DS; Park, JH, 2011)
"In this prospective study, 1,212 patients with acute coronary syndromes were randomly assigned to receive either standard dual-antiplatelet treatment with aspirin and clopidogrel (n = 608) or triple-antiplatelet therapy with the addition of a 6-month course of cilostazol (n = 604) after successful PCI."5.14Cilostazol in addition to aspirin and clopidogrel improves long-term outcomes after percutaneous coronary intervention in patients with acute coronary syndromes: a randomized, controlled study. ( Han, Y; Jing, Q; Li, Y; Shu, Q; Tang, X; Wang, D; Wang, S; Wang, Z, 2009)
"Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor antagonist is the standard of care in acute coronary syndromes."4.89Triple versus dual antiplatelet therapy in acute coronary syndromes: adding cilostazol to aspirin and clopidogrel? ( Bangalore, S; Dinicolantonio, JJ; Lavie, CJ; Meier, P; Niazi, AK; O'Keefe, JH, 2013)
" In the last few years, cilostazol, a phosphodiesterase (PDE) 3 inhibitor, has been tested in the setting of acute coronary syndromes: it exerts not only anti-platelet actions, but also pleiotropic effects, including inhibition on neointimal hyperplasia, therefore preventing both stent restenosis and thrombosis."4.88Cilostazol and primary-PCI: mirage or good alternative? ( Crea, F; D'Amario, D; Porto, I, 2012)
"Dual antiplatelet therapy with aspirin and clopidogrel is a well-established standard of care for patients with acute coronary syndromes."4.87Beyond aspirin and clopidogrel: is there a need for additional antiplatelet therapy in ACS? ( Moliterno, DJ; Rajan, L, 2011)
"Cilostazol 100 mg b."2.75Effect of cilostazol on platelet aggregation in patients with non-ST elevation acute coronary syndrome. ( Ahluwalia, J; Bhalla, A; Malhotra, S; Pandhi, P; Pattanaik, S; Sharma, YP, 2010)
" Endpoints included major adverse cardiac effects (MACEs), target lesion revascularization (TLR), target vessel revascularization (TVR), death, stent thrombosis, bleeding and adverse drug reactions during a 9-12 months period, as well as platelet activities."2.52Comparing the effectiveness and safety between triple antiplatelet therapy and dual antiplatelet therapy in type 2 diabetes mellitus patients after coronary stents implantation: a systematic review and meta-analysis of randomized controlled trials. ( Bundhun, PK; Chen, MH; Qin, T, 2015)
"Cilostazol is a specific and strong inhibitor of phosphodiesterase (PDE) type III which can suppress the platelet aggregation by increasing cyclic adenosine monophosphate (cAMP) levels."1.62Cilostazol increases adenosine plasma concentration in patients with acute coronary syndrome. ( Chen, J; Li, X; Lv, Q; Wang, Z; Wu, H; Xue, Y, 2021)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's11 (84.62)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Xue, Y1
Wang, Z2
Wu, H1
Li, X1
Chen, J1
Lv, Q1
Vieira, MS1
Niazi, AK1
Dinicolantonio, JJ1
Lavie, CJ1
O'Keefe, JH1
Meier, P1
Bangalore, S1
Lee, K1
Yoo, SY1
Suh, J1
Park, KH1
Park, Y1
Tantry, US1
Park, KS1
Han, SH1
Kang, WC1
Shin, DH1
Lee, C1
Choi, SW1
Lee, JH1
Cho, YH1
Lee, NH1
Jeong, MH1
Ahn, Y1
Kubica, J1
Gurbel, PA1
Park, JH2
Jeong, YH1
Bundhun, PK1
Qin, T1
Chen, MH1
Han, Y1
Li, Y2
Wang, S1
Jing, Q1
Wang, D1
Shu, Q1
Tang, X1
Pattanaik, S1
Malhotra, S1
Sharma, YP1
Ahluwalia, J1
Bhalla, A1
Pandhi, P1
Ahn, CM1
Hong, SJ1
Kim, JS1
Lim, DS1
Rajan, L1
Moliterno, DJ1
Ferreiro, JL1
Cequier, AR1
Angiolillo, DJ1
Porto, I1
D'Amario, D1
Crea, F1
Guan, SY1
Han, YL1
Guo, L1
Yang, BS1
Wang, SL1
Jing, QM1
Wang, XZ1
Ma, YY1
Liu, XD1
Geng, DF1
Liu, M1
Jin, DM1
Wu, W1
Deng, J1
Wang, JF1

Reviews

6 reviews available for cilostazol and Acute Coronary Syndrome

ArticleYear
Triple versus dual antiplatelet therapy in acute coronary syndromes: adding cilostazol to aspirin and clopidogrel?
    Cardiology, 2013, Volume: 126, Issue:4

    Topics: Acute Coronary Syndrome; Aspirin; Cilostazol; Clinical Trials as Topic; Clopidogrel; Drug Therapy, C

2013
Comparing the effectiveness and safety between triple antiplatelet therapy and dual antiplatelet therapy in type 2 diabetes mellitus patients after coronary stents implantation: a systematic review and meta-analysis of randomized controlled trials.
    BMC cardiovascular disorders, 2015, Oct-09, Volume: 15

    Topics: Acute Coronary Syndrome; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Diabetes Mellitu

2015
Beyond aspirin and clopidogrel: is there a need for additional antiplatelet therapy in ACS?
    Current cardiology reports, 2011, Volume: 13, Issue:4

    Topics: Acute Coronary Syndrome; Adenosine; Adenosine Monophosphate; Aspirin; Cilostazol; Clopidogrel; Drug

2011
Oral antiplatelet therapy in patients with diabetes mellitus and acute coronary syndromes.
    Trends in cardiovascular medicine, 2010, Volume: 20, Issue:7

    Topics: Acute Coronary Syndrome; Administration, Oral; Aspirin; Cilostazol; Clopidogrel; Diabetes Complicati

2010
Cilostazol and primary-PCI: mirage or good alternative?
    Current vascular pharmacology, 2012, Volume: 10, Issue:4

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Arrhythmias, Cardiac; Aspirin; Cilostazol;

2012
Cilostazol-based triple antiplatelet therapy compared to dual antiplatelet therapy in patients with coronary stent implantation: a meta-analysis of 5,821 patients.
    Cardiology, 2012, Volume: 122, Issue:3

    Topics: Acute Coronary Syndrome; Aspirin; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Cil

2012

Trials

5 trials available for cilostazol and Acute Coronary Syndrome

ArticleYear
Efficacy of cilostazol on inhibition of platelet aggregation, inflammation and myonecrosis in acute coronary syndrome patients undergoing percutaneous coronary intervention: The ACCEL-LOADING-ACS (ACCELerated Inhibition of Platelet Aggregation, Inflammati
    International journal of cardiology, 2015, Volume: 190

    Topics: Acute Coronary Syndrome; Aged; Cilostazol; Drug Administration Schedule; Female; Humans; Inflammatio

2015
Cilostazol in addition to aspirin and clopidogrel improves long-term outcomes after percutaneous coronary intervention in patients with acute coronary syndromes: a randomized, controlled study.
    American heart journal, 2009, Volume: 157, Issue:4

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Ci

2009
Effect of cilostazol on platelet aggregation in patients with non-ST elevation acute coronary syndrome.
    International journal of clinical pharmacology and therapeutics, 2010, Volume: 48, Issue:2

    Topics: Acute Coronary Syndrome; Adult; Aged; Aspirin; Cilostazol; Clopidogrel; Double-Blind Method; Drug Th

2010
Cilostazol reduces the progression of carotid intima-media thickness without increasing the risk of bleeding in patients with acute coronary syndrome during a 2-year follow-up.
    Heart and vessels, 2011, Volume: 26, Issue:5

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Analysis of Variance; Angioplasty, Balloon, Corona

2011
[Effects of intensive antiplatelet therapy for patients with high on-treatment platelet reactivity after coronary stent implantation].
    Zhonghua xin xue guan bing za zhi, 2012, Volume: 40, Issue:1

    Topics: Acute Coronary Syndrome; Adult; Aged; Aspirin; Blood Platelets; Cilostazol; Clopidogrel; Drug Therap

2012

Other Studies

2 other studies available for cilostazol and Acute Coronary Syndrome

ArticleYear
Cilostazol increases adenosine plasma concentration in patients with acute coronary syndrome.
    Journal of clinical pharmacy and therapeutics, 2021, Volume: 46, Issue:2

    Topics: Acute Coronary Syndrome; Adenosine; Adenosine Diphosphate; Aged; Aspirin; China; Cilostazol; Clopido

2021
Tailoring antiplatelet therapy in acute coronary syndromes: the thin red line.
    Cardiology, 2013, Volume: 126, Issue:4

    Topics: Acute Coronary Syndrome; Cilostazol; Humans; Phosphodiesterase 3 Inhibitors; Platelet Aggregation In

2013