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cilostamide and Cardiac Failure

cilostamide has been researched along with Cardiac Failure in 6 studies

cilostamide: selective inhibitor of cyclic AMP phosphodiesterase & platelet aggregation; structure

Research Excerpts

ExcerptRelevanceReference
"The β-blockers carvedilol and metoprolol provide important therapeutic strategies for heart failure treatment."3.80Carvedilol induces greater control of β2- than β 1-adrenoceptor-mediated inotropic and lusitropic effects by PDE3, while PDE4 has no effect in human failing myocardium. ( Berk, E; Christ, T; Engel, A; Galindo-Tovar, A; Gillette, KT; Kaumann, AJ; Molenaar, P; Ravens, U, 2014)
"Heart failure was induced in male Wistar rats by coronary artery ligation."1.36Natriuretic peptides increase beta1-adrenoceptor signalling in failing hearts through phosphodiesterase 3 inhibition. ( Aronsen, JM; Hougen, K; Levy, FO; Moltzau, LR; Nguyen, CH; Osnes, JB; Qvigstad, E; Sjaastad, I; Skomedal, T, 2010)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Orstavik, O1
Ata, SH1
Riise, J1
Dahl, CP1
Andersen, GØ1
Levy, FO3
Skomedal, T3
Osnes, JB3
Qvigstad, E2
Molenaar, P1
Christ, T1
Berk, E1
Engel, A1
Gillette, KT1
Galindo-Tovar, A1
Ravens, U1
Kaumann, AJ1
Hubert, F1
Belacel-Ouari, M1
Manoury, B1
Zhai, K1
Domergue-Dupont, V1
Mateo, P1
Joubert, F1
Fischmeister, R1
Leblais, V1
Moltzau, LR1
Aronsen, JM2
Nguyen, CH1
Hougen, K1
Sjaastad, I2
Hussain, RI1
Afzal, F1
Krobert, KA1
Tarpey, SB1
Sawmiller, DR1
Kelly, C1
Thompson, WJ1
Townsley, MI1

Other Studies

6 other studies available for cilostamide and Cardiac Failure

ArticleYear
Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart.
    British journal of pharmacology, 2014, Volume: 171, Issue:23

    Topics: Adrenergic beta-Agonists; Animals; Calcium; Cardiotonic Agents; Heart; Heart Failure; Humans; Hydraz

2014
Carvedilol induces greater control of β2- than β 1-adrenoceptor-mediated inotropic and lusitropic effects by PDE3, while PDE4 has no effect in human failing myocardium.
    Naunyn-Schmiedeberg's archives of pharmacology, 2014, Volume: 387, Issue:7

    Topics: Adrenergic beta-Antagonists; Adult; Carbazoles; Carvedilol; Cyclic Nucleotide Phosphodiesterases, Ty

2014
Alteration of vascular reactivity in heart failure: role of phosphodiesterases 3 and 4.
    British journal of pharmacology, 2014, Volume: 171, Issue:23

    Topics: Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Cyclic Nucleotide Phosphodiesterases, Type 3; Cy

2014
Natriuretic peptides increase beta1-adrenoceptor signalling in failing hearts through phosphodiesterase 3 inhibition.
    Cardiovascular research, 2010, Mar-01, Volume: 85, Issue:4

    Topics: Animals; Apoptosis; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide

2010
The functional activity of inhibitory G protein (G(i)) is not increased in failing heart ventricle.
    Journal of molecular and cellular cardiology, 2013, Volume: 56

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Carbachol; Cardiotonic Agents; GTP-Binding Pro

2013
Phosphodiesterase 3 activity is reduced in dog lung following pacing-induced heart failure.
    American journal of physiology. Lung cellular and molecular physiology, 2003, Volume: 284, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Capillaries; Capillary Permeability; Colforsin; Cyclic

2003