cilomilast has been researched along with Inflammation in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (75.00) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Alonso, JM; Andrés, JI; Boeckx, G; Cools, M; de Chaffoy, D; De Clerck, F; Deroose, F; Díaz, A; Diels, G; Fernández, J; Freyne, EJ; Iturrino, L; Martínez, P; Matesanz, E; Megens, A; Peeters, D; Petit, D; Somers, M; Stoppie, P; Van Wauwe, J | 1 |
| Huang, S; Jia, Z; Meng, X; Xu, M; Yu, X; Zhang, A; Zhang, Y | 1 |
| Ammit, AJ; Baehring, G; Kugel, MJ; Patel, BS | 1 |
| Balachandran, S; Chaudhary, S; Dastidar, SG; Gupta, N; Nanda, K; Palle, V; Rajagopal, D; Ray, A; Seth, MK; Sharma, P; Shirumalla, R | 1 |
| Bertin, B; Bertrand, CP; Bouget, A; Burnouf, C; Doherty, AM; Dubuit, JP; Julien-Larose, C; Lagente, V; Leportier, C; Martin, B; Moreau, F; Ouaged, M; Pruniaux, MP; Rocher, MN | 1 |
| Asaka, N; Kakuo, H; Kiniwa, M; Ohmori, K; Oka, T; Sasaki, E; Togawa, M; Yamada, S | 1 |
| Bäumer, W; Ehinger, AM; Gorr, G; Hoppmann, J; Kietzmann, M; Rundfeldt, C | 1 |
| Devillier, P | 1 |
| Kerstjens, HA; Timens, W | 1 |
| Hanania, NA; Soto, FJ | 1 |
| Wang, ZL | 1 |
| Celli, B | 1 |
| Bitter-Suermann, S; Kanniess, F; Magnussen, H; Watz, H | 1 |
| Fujimura, M; Liu, Q | 1 |
| Cantinieaux, B; Cataldo, D; Delvaux, C; Dentener, M; Michel, O; Murdoch, RD; Vertongen, F | 1 |
| Chapman, R; Fine, J; Jones, H; Kreutner, W; Kung, TT; Minnicozzi, M; Spond, J | 1 |
5 review(s) available for cilomilast and Inflammation
| Article | Year |
|---|---|
[Physiopathology of COPD: choosing the right therapeutic targets].
Topics: Adrenal Cortex Hormones; Aged; Albuterol; Animals; Bacterial Infections; Bronchodilator Agents; Carboxylic Acids; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Therapy, Combination; Humans; Inflammation; Mucociliary Clearance; Nitriles; Phosphodiesterase Inhibitors; Pulmonary Alveoli; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Randomized Controlled Trials as Topic; Rats; Rolipram; Salmeterol Xinafoate; Smoking; Theophylline; Time Factors | 2003 |
Phosphodiesterase 4 inhibitors: antiinflammatory therapy for chronic obstructive pulmonary disease at last?
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Anti-Inflammatory Agents; Bronchodilator Agents; Carboxylic Acids; CD8-Positive T-Lymphocytes; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Humans; Inflammation; Leukocyte Count; Neutrophils; Nitriles; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive | 2003 |
Selective phosphodiesterase-4 inhibitors in chronic obstructive lung disease.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amides; Aminopyridines; Benzamides; Carboxylic Acids; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Cyclopropanes; Humans; Indoles; Inflammation; Lung; Nitriles; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pulmonary Disease, Chronic Obstructive | 2005 |
Research on airway inflammation: present status in Mainland China.
Topics: Animals; Asthma; Cyclohexanecarboxylic Acids; Cytokines; Eosinophils; Genetic Therapy; Humans; Inflammation; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Nitriles; Quinolines; Signal Transduction | 2005 |
[Pharmacological treatment of COPD and future of anti-inflammatory therapy].
Topics: Acetylcysteine; Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Bronchodilator Agents; Carboxylic Acids; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Dyspnea; Expectorants; Forced Expiratory Volume; Forecasting; Humans; Inflammation; Infliximab; Lung; Macrolides; Nitriles; Phosphodiesterase Inhibitors; Pilot Projects; Pulmonary Disease, Chronic Obstructive; Randomized Controlled Trials as Topic; Research; Respiratory Function Tests; Simvastatin; Smoking Cessation; Tetracycline; Theophylline; Tumor Necrosis Factor-alpha | 2006 |
1 trial(s) available for cilomilast and Inflammation
| Article | Year |
|---|---|
Evaluation of oral corticosteroids and phosphodiesterase-4 inhibitor on the acute inflammation induced by inhaled lipopolysaccharide in human.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Anti-Inflammatory Agents; C-Reactive Protein; Carboxylic Acids; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; E-Selectin; Female; Glucocorticoids; Humans; Inflammation; Lipopolysaccharides; Male; Matrix Metalloproteinase 9; Middle Aged; Neutrophils; Nitriles; Phosphodiesterase Inhibitors; Prednisolone; Sputum; Tissue Inhibitor of Metalloproteinase-1; Tumor Necrosis Factor-alpha | 2007 |
10 other study(ies) available for cilomilast and Inflammation
| Article | Year |
|---|---|
Synthesis and biological evaluation of imidazol-2-one and 2-cyanoiminoimidazole derivatives: novel series of PDE4 inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Topical; Animals; Anti-Inflammatory Agents; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Dose-Response Relationship, Drug; Ear Diseases; Enzyme Inhibitors; Humans; Imidazoles; Inflammation; Inhibitory Concentration 50; Rats; Structure-Activity Relationship | 2002 |
Inhibition of PDE4/PDE4B improves renal function and ameliorates inflammation in cisplatin-induced acute kidney injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; Cells, Cultured; Cisplatin; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Epithelial Cells; Gene Expression Regulation, Enzymologic; Gene Knockdown Techniques; Inflammation; Kidney Tubules; Male; Mice; Nitriles; Phosphodiesterase 4 Inhibitors; RNA, Messenger | 2020 |
Doxofylline does not increase formoterol-induced cAMP nor MKP-1 expression in ASM cells resulting in lack of anti-inflammatory effect.
Topics: Anti-Inflammatory Agents; Bronchi; Bronchodilator Agents; Cells, Cultured; Cyclic AMP; Cyclohexanecarboxylic Acids; Dual Specificity Phosphatase 1; Formoterol Fumarate; Humans; Inflammation; Interleukin-8; Myocytes, Smooth Muscle; Nitriles; Phosphodiesterase Inhibitors; Theophylline; Tumor Necrosis Factor-alpha | 2017 |
Pharmacology of a novel, orally active PDE4 inhibitor.
Topics: Animals; Carboxylic Acids; Cell Line, Transformed; Cyclic AMP; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dogs; Female; Guinea Pigs; Humans; Inflammation; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Nitriles; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Rolipram; Tumor Necrosis Factor-alpha; Vomiting | 2009 |
Relationship between phosphodiesterase type 4 inhibition and anti-inflammatory activity of CI-1044 in rat airways.
Topics: Administration, Oral; Animals; Azepines; Carboxylic Acids; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Inflammation; Inhibitory Concentration 50; Lipopolysaccharides; Male; Niacinamide; Nitriles; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pulmonary Eosinophilia; Rats; Rats, Inbred BN; Rolipram; Tumor Necrosis Factor-alpha | 2010 |
Effects of the new benzimidazole derivative TAS-203, an orally active phosphodiesterase 4 inhibitor, on airway inflammation in rats and emetic responses in ferrets.
Topics: Animals; Anti-Inflammatory Agents; Benzimidazoles; Chemotaxis, Leukocyte; Cloning, Molecular; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Ferrets; Guinea Pigs; Humans; Inflammation; Lipopolysaccharides; Male; Nitriles; Phosphodiesterase 4 Inhibitors; Platelet Activating Factor; Rats; Rats, Inbred BN; Rats, Inbred Lew; Respiratory Tract Diseases; Tissue Distribution; Triazoles; Tumor Necrosis Factor-alpha; Vomiting | 2010 |
AWD 12-281, a highly selective phosphodiesterase 4 inhibitor, is effective in the prevention and treatment of inflammatory reactions in a model of allergic dermatitis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Oral; Administration, Topical; Amides; Animals; Bronchodilator Agents; Carboxylic Acids; Cattle; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Cytokines; Dermatitis, Allergic Contact; Disease Models, Animal; Ear; Female; Indoles; Inflammation; Inflammation Mediators; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Nitriles; Time Factors; Toluene | 2003 |
COPD, inflammation and its modulation by phosphodiesterase 4 inhibitors: time to look beyond the FEV1.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Carboxylic Acids; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Forced Expiratory Volume; Humans; Inflammation; Nitriles; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive; Treatment Outcome | 2006 |
Selective inhibitors for phosphodiesterase 3 and 4 in antigen-induced increase of cough reflex sensitivity in guinea pigs.
Topics: Allergens; Animals; Antigens; Bronchoalveolar Lavage; Capsaicin; Cough; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Eosinophilia; Guinea Pigs; Imidazoles; Inflammation; Injections, Intraperitoneal; Male; Nitriles; Phosphodiesterase 3 Inhibitors; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pyridones; Reflex | 2007 |
Comparison of PDE 4 inhibitors, rolipram and SB 207499 (ariflo), in a rat model of pulmonary neutrophilia.
Topics: Adrenalectomy; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Humans; Inflammation; Interleukin-1; Lung Diseases; Lung Diseases, Obstructive; Male; Neutrophils; Nitriles; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Rolipram; Tumor Necrosis Factor-alpha | 2001 |