cilengitide has been researched along with Melanoma in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Corti, A; Curnis, F; Ghitti, M; Gori, A; Musco, G; Nardelli, F; Paissoni, C; Quilici, G; Sacchi, A; Traversari, C; Valentinis, B | 1 |
| Im, H; Lee, J; Ryu, KY; Yi, JY | 1 |
| Ding, Y; Lu, W; Tang, Y; Tao, X; Zhu, X | 1 |
| Bertram, A; Hendruschk, S; Kirsch, M; Liebner, C; Lord, EM; Martin, DK; Schackert, G; Sitoci-Ficici, KH; Temme, A; Uckermann, O | 1 |
| D'Atri, S; Graziani, G; Lacal, PM; Levati, L; Ruffini, F; Tentori, L | 1 |
| Bedikian, AY; Camacho, LH; Colevas, AD; Diwan, AH; Gallick, GE; Hwu, P; Johnson, MM; Joseph, RW; Kim, KB; Ng, CS; Papadopoulos, NE; Prieto, V; Reckeweg, A; Vardeleon, A; Wei, W; Wittemer, SM | 1 |
| Tucker, GC | 1 |
| Dorio, AS; Graziani, G; Lacal, PM; Muzi, A; Navarra, P; Ruffini, F; Tentori, L | 1 |
| Fittschen, C; Goodman, S; Jonczyk, A; Marshall, JF; Meyer, T; Mitjans, F; Piulats, J; Reyes, G | 1 |
1 review(s) available for cilengitide and Melanoma
| Article | Year |
|---|---|
Integrins: molecular targets in cancer therapy.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biomarkers, Tumor; Central Nervous System Neoplasms; Clinical Trials as Topic; Glioblastoma; Humans; Indoles; Integrins; Melanoma; Neoplasms; Porphyrins; Skin Neoplasms; Snake Venoms; Sulfonamides | 2006 |
1 trial(s) available for cilengitide and Melanoma
| Article | Year |
|---|---|
A randomized phase II study of cilengitide (EMD 121974) in patients with metastatic melanoma.
Topics: Adult; Aged; Aged, 80 and over; Disease-Free Survival; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Skin Neoplasms; Snake Venoms | 2012 |
7 other study(ies) available for cilengitide and Melanoma
| Article | Year |
|---|---|
Succinimide-Based Conjugates Improve IsoDGR Cyclopeptide Affinity to α
Topics: Allosteric Regulation; Binding, Competitive; Cell Line, Tumor; Cell Membrane; HEK293 Cells; Humans; Integrin alphaVbeta3; Magnetic Resonance Spectroscopy; Melanoma; Molecular Docking Simulation; Peptides, Cyclic; Protein Conformation; Snake Venoms; Structure-Activity Relationship; Succinimides; Tyrosine | 2018 |
Integrin αvβ3-Akt signalling plays a role in radioresistance of melanoma.
Topics: Cell Line, Tumor; Cell Survival; Gamma Rays; Heterocyclic Compounds, 3-Ring; Humans; Integrin alphaVbeta3; Melanoma; Proto-Oncogene Proteins c-akt; Radiation Tolerance; Signal Transduction; Skin Neoplasms; Snake Venoms | 2020 |
Blockade of integrin β3 signals to reverse the stem-like phenotype and drug resistance in melanoma.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; Integrin beta3; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplastic Stem Cells; Phenotype; Signal Transduction; Snake Venoms; Xenograft Model Antitumor Assays | 2019 |
Differential growth inhibition of cerebral metastases by anti-angiogenic compounds.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; Combined Modality Therapy; Female; Genetic Therapy; Interleukin-12; Melanoma; Mice; Mice, Nude; Peptides, Cyclic; Snake Venoms; Transfection | 2014 |
Cilengitide downmodulates invasiveness and vasculogenic mimicry of neuropilin 1 expressing melanoma cells through the inhibition of αvβ5 integrin.
Topics: Cell Line, Tumor; Focal Adhesion Protein-Tyrosine Kinases; Humans; Melanoma; Neoplasm Invasiveness; Neuropilin-1; Receptors, Vitronectin; Snake Venoms; Vascular Endothelial Growth Factor Receptor-2 | 2015 |
The integrin antagonist cilengitide increases the antitumor activity of temozolomide against malignant melanoma.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Dacarbazine; DNA Mismatch Repair; Drug Synergism; Endothelial Cells; Integrins; Male; Melanoma; Mice; Mice, Inbred C57BL; Snake Venoms; Temozolomide | 2008 |
In vivo therapy of malignant melanoma by means of antagonists of alphav integrins.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antineoplastic Agents; Cell Adhesion; Cell Division; Disease Progression; Dose-Response Relationship, Drug; Growth Inhibitors; HT29 Cells; Humans; Integrins; Kinetics; Male; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Peptides, Cyclic; Receptors, Vitronectin; Snake Venoms; Tumor Cells, Cultured | 2000 |