Page last updated: 2024-09-05

cilengitide and Invasiveness, Neoplasm

cilengitide has been researched along with Invasiveness, Neoplasm in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's11 (84.62)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Böhmer, FD; Braunsdorf, WE; Hass, P; Helbing, C; Kirches, E; Kliese, N; Mawrin, C; Pachow, D; Pasemann, D; Schneider, T; Warnke, JP; Wilisch-Neumann, A1
Date, I; Ichikawa, T; Kurozumi, K; Onishi, M2
Cheng, NC; Reid, G; van Zandwijk, N1
Adamska, K; Aldape, KD; Brandes, AA; Erridge, SC; Gorlia, T; Grujicic, D; Gupta, T; Hau, P; Hegi, ME; Herrlinger, U; Hicking, C; Hong, YK; Kim, CY; Kortmann, RD; Lhermitte, B; Markivskyy, A; McBain, C; Nabors, LB; Nam, DH; Perry, J; Picard, M; Pietsch, T; Rao, N; Reardon, DA; Schnell, O; Shen, CC; Steinbach, JP; Stupp, R; Taphoorn, MJ; Tarnawski, R; Thurzo, L; Tonn, JC; van den Bent, MJ; Weller, M; Weyerbrock, A; Wick, W; Wiegel, T1
D'Atri, S; Graziani, G; Lacal, PM; Levati, L; Ruffini, F; Tentori, L1
Date, I; Ichikawa, T; Ishida, J; Kurozumi, K; Shimizu, T1
Adams, B; Maurer, GD; Stupp, R; Tabatabai, G; Tritschler, I; Weller, M; Wick, W1
Imaizumi, N; Kuonen, F; Monnier, Y; Rüegg, C1
Bäuerle, T; Berger, MR; Bretschi, M; Komljenovic, D; Merz, M; Semmler, W1
Date, I; Fujii, K; Ichikawa, T; Kurozumi, K; Onishi, M1
Chiocca, EA; Date, I; Fujii, K; Ichikawa, T; Inoue, S; Kaur, B; Kurozumi, K; Michiue, H; Onishi, M; Yoshida, K1
Sasaki, H; Yoshida, K1

Reviews

5 review(s) available for cilengitide and Invasiveness, Neoplasm

ArticleYear
Mechanisms of tumor development and anti-angiogenic therapy in glioblastoma multiforme.
    Neurologia medico-chirurgica, 2013, Volume: 53, Issue:11

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Cell Adhesion; Combined Modality Therapy; Glioblastoma; Humans; Integrin alphaVbeta3; Neoplasm Invasiveness; Neoplasm Proteins; Neovascularization, Pathologic; Snake Venoms; Vascular Endothelial Growth Factor A

2013
Adhesion molecules and the extracellular matrix as drug targets for glioma.
    Brain tumor pathology, 2016, Volume: 33, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies; Brain Neoplasms; Cell Adhesion Molecules; Disease Progression; Extracellular Matrix; Glioma; Humans; Molecular Targeted Therapy; Neoplasm Invasiveness; Neovascularization, Pathologic; Snake Venoms; Thalidomide; White Matter

2016
Angiogenesis and invasion in glioma.
    Brain tumor pathology, 2011, Volume: 28, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Disease Models, Animal; Endothelial Cells; Extracellular Matrix; Glioma; Humans; Mice; Molecular Targeted Therapy; Neoplasm Invasiveness; Neovascularization, Pathologic; Rats; Snake Venoms; Tenascin; Thalidomide

2011
Cilengitide treatment for malignant glioma: current status and future direction.
    Neurologia medico-chirurgica, 2012, Volume: 52, Issue:8

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Clinical Trials as Topic; Glioma; Humans; Integrins; Neoplasm Invasiveness; Snake Venoms

2012
[Inhibition of cellular adhesion and invasion in gliomas].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cathepsin B; Cell Adhesion; Clinical Trials as Topic; Drug Design; Extracellular Matrix; Glioma; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hydroxamic Acids; Integrins; Laminin; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Multigene Family; Neoplasm Invasiveness; Signal Transduction; Snake Venoms; Urokinase-Type Plasminogen Activator

2005

Trials

1 trial(s) available for cilengitide and Invasiveness, Neoplasm

ArticleYear
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Confidence Intervals; Dacarbazine; Disease-Free Survival; DNA Modification Methylases; DNA Repair Enzymes; Dose-Response Relationship, Drug; Drug Administration Schedule; Early Detection of Cancer; Female; Follow-Up Studies; Glioblastoma; Humans; Kaplan-Meier Estimate; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Patient Selection; Promoter Regions, Genetic; Proportional Hazards Models; Reference Values; Snake Venoms; Survival Analysis; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins

2014

Other Studies

7 other study(ies) available for cilengitide and Invasiveness, Neoplasm

ArticleYear
The integrin inhibitor cilengitide affects meningioma cell motility and invasion.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Oct-01, Volume: 19, Issue:19

    Topics: Animals; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Models, Animal; Humans; Immunohistochemistry; Integrins; Meningeal Neoplasms; Meningioma; Mice; Neoplasm Invasiveness; Neurofibromin 2; Receptors, Vitronectin; Snake Venoms; Tumor Burden

2013
Cilengitide inhibits attachment and invasion of malignant pleural mesothelioma cells through antagonism of integrins αvβ3 and αvβ5.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Cell Adhesion; Cell Line, Tumor; Humans; Integrin alphaVbeta3; Mesothelioma; Neoplasm Invasiveness; Pleural Neoplasms; Receptors, Vitronectin; Snake Venoms

2014
Cilengitide downmodulates invasiveness and vasculogenic mimicry of neuropilin 1 expressing melanoma cells through the inhibition of αvβ5 integrin.
    International journal of cancer, 2015, Mar-15, Volume: 136, Issue:6

    Topics: Cell Line, Tumor; Focal Adhesion Protein-Tyrosine Kinases; Humans; Melanoma; Neoplasm Invasiveness; Neuropilin-1; Receptors, Vitronectin; Snake Venoms; Vascular Endothelial Growth Factor Receptor-2

2015
Cilengitide modulates attachment and viability of human glioma cells, but not sensitivity to irradiation or temozolomide in vitro.
    Neuro-oncology, 2009, Volume: 11, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; bcl-X Protein; Brain Neoplasms; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Survival; Dacarbazine; DNA Methylation; Drug Therapy, Combination; Gene Silencing; Glioma; Humans; Immunoblotting; In Vitro Techniques; Integrin alphaVbeta3; Mice; Neoplasm Invasiveness; NIH 3T3 Cells; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, Vitronectin; Snake Venoms; Temozolomide; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2009
Radiation-induced modifications of the tumor microenvironment promote metastasis.
    Bulletin du cancer, 2011, Volume: 98, Issue:6

    Topics: Angiogenesis Inhibitors; Cell Hypoxia; Cell Movement; Cell Proliferation; Cysteine-Rich Protein 61; Disease Progression; Endothelial Cells; Humans; Microvessels; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Neovascularization, Pathologic; Receptors, Vitronectin; Snake Venoms; Tumor Microenvironment

2011
Cilengitide inhibits metastatic bone colonization in a nude rat model.
    Oncology reports, 2011, Volume: 26, Issue:4

    Topics: Animals; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Female; Humans; Magnetic Resonance Imaging; Neoplasm Invasiveness; Osteoclasts; Rats; Rats, Nude; Snake Venoms; Xenograft Model Antitumor Assays

2011
Bimodal anti-glioma mechanisms of cilengitide demonstrated by novel invasive glioma models.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2013, Volume: 33, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Coculture Techniques; Disease Models, Animal; Dogs; Glioma; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Rats; Rats, Nude; Snake Venoms; Xenograft Model Antitumor Assays

2013