Page last updated: 2024-09-05

cilengitide and Angiogenesis, Pathologic

cilengitide has been researched along with Angiogenesis, Pathologic in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.00)18.2507
2000's5 (25.00)29.6817
2010's14 (70.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bazzazi, H; Jafarnejad, M; Popel, AS; Zhang, Y1
Date, I; Ichikawa, T; Kurozumi, K; Onishi, M2
Carme, S; Ceelen, W; De Naeyer, D; Debergh, I; Demetter, P; Pattyn, P; Robert, P; Smeets, P; Van Damme, N1
Ameratunga, MS; Grant, R; Khasraw, M; Pavlakis, N; Wheeler, H1
Ahn, H; Amorós, M; Bolontrade, M; Cayrol, F; Cerchietti, L; Cremaschi, GA; Díaz Flaqué, MC; Farías, RN; Fernando, T; Inghirami, G; Isse, B; Singh, A; Sterle, HA; Tabbò, F; Tian, YF; Yang, SN1
Alrawashdeh, W; Cereser, B; Crnogorac-Jurcevic, T; Demircioglu, F; Elia, G; Ghazaly, E; Hagemann, T; Hodivala-Dilke, KM; Kocher, HM; McDonald, S; Scudamore, CL; Stratford, MR; Wong, PP1
Cohen, EE; Fleming, GF; Harris, PJ; Janisch, L; Karovic, S; Karrison, TG; Levine, MR; Maitland, ML; O'Donnell, PH; Polite, BN; Ratain, MJ1
Bergers, G; Rivera, LB1
Date, I; Ichikawa, T; Ishida, J; Kurozumi, K; Shimizu, T1
Gramatzki, D; Roth, P; Seystahl, K; Weller, M1
Nabors, B; Reardon, D; Stupp, R; Weller, M1
Imaizumi, N; Kuonen, F; Monnier, Y; Rüegg, C1
Bäuerle, T; Bretschi, M; Cheng, C; Dimitrakopoulou-Strauss, A; Semmler, W; Strauss, LG; Witt, H1
DeWitt, JP; Han, JH; Kim, B; Kim, CY; Kim, SK; Kim, YH; Lee, JE; Lee, JK; Oh, CW1
Dubowitz, DJ; Fraser, S; Gonzalez-Gomez, I; Jacobs, R; Khankaldyyan, V; Laug, WE; Moats, RA; Nelson, MD; Schultz, L; Taga, T; Velan-Mullan, S1
Goodman, SL; Jonczyk, A; Nisato, RE; Pepper, MS; Tille, JC1
Akella, NS; Cloud, GA; Grossman, S; Hochberg, FH; Mikkelsen, T; Nabors, LB; Twieg, DB1
Bu, XY; Gonzales-Gomez, I; Khankaldyyan, V; Laug, WE; McComb, JG; Yamada, S1
Cheresh, DA; Gillies, SD; Jonczyk, A; Lode, HN; Moehler, T; Reisfeld, RA; Xiang, R1

Reviews

5 review(s) available for cilengitide and Angiogenesis, Pathologic

ArticleYear
Mechanisms of tumor development and anti-angiogenic therapy in glioblastoma multiforme.
    Neurologia medico-chirurgica, 2013, Volume: 53, Issue:11

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Cell Adhesion; Combined Modality Therapy; Glioblastoma; Humans; Integrin alphaVbeta3; Neoplasm Invasiveness; Neoplasm Proteins; Neovascularization, Pathologic; Snake Venoms; Vascular Endothelial Growth Factor A

2013
Antiangiogenic therapy for high-grade glioma.
    The Cochrane database of systematic reviews, 2014, Sep-22, Issue:9

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Camptothecin; Dacarbazine; Glioblastoma; Humans; Hypertension; Irinotecan; Lomustine; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Proteinuria; Randomized Controlled Trials as Topic; Snake Venoms; Temozolomide

2014
Adhesion molecules and the extracellular matrix as drug targets for glioma.
    Brain tumor pathology, 2016, Volume: 33, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies; Brain Neoplasms; Cell Adhesion Molecules; Disease Progression; Extracellular Matrix; Glioma; Humans; Molecular Targeted Therapy; Neoplasm Invasiveness; Neovascularization, Pathologic; Snake Venoms; Thalidomide; White Matter

2016
Pharmacotherapies for the treatment of glioblastoma - current evidence and perspectives.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:9

    Topics: Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblastoma; Humans; Neovascularization, Pathologic; Snake Venoms; Temozolomide

2016
Angiogenesis and invasion in glioma.
    Brain tumor pathology, 2011, Volume: 28, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Disease Models, Animal; Endothelial Cells; Extracellular Matrix; Glioma; Humans; Mice; Molecular Targeted Therapy; Neoplasm Invasiveness; Neovascularization, Pathologic; Rats; Snake Venoms; Tenascin; Thalidomide

2011

Trials

2 trial(s) available for cilengitide and Angiogenesis, Pathologic

ArticleYear
Serum C-Telopeptide Collagen Crosslinks and Plasma Soluble VEGFR2 as Pharmacodynamic Biomarkers in a Trial of Sequentially Administered Sunitinib and Cilengitide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Nov-15, Volume: 21, Issue:22

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Biomarkers, Tumor; Collagen Type I; Female; Humans; Indoles; Male; Middle Aged; Neoplasm Staging; Neoplasms; Neovascularization, Pathologic; Peptides; Pyrroles; Snake Venoms; Sunitinib; Vascular Endothelial Growth Factor Receptor-2

2015
Assessment of brain tumor angiogenesis inhibitors using perfusion magnetic resonance imaging: quality and analysis results of a phase I trial.
    Journal of magnetic resonance imaging : JMRI, 2004, Volume: 20, Issue:6

    Topics: Angiogenesis Inhibitors; Blood Flow Velocity; Blood Volume; Brain Neoplasms; Disease Progression; Echo-Planar Imaging; Glioblastoma; Glioma; Humans; Magnetic Resonance Angiography; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Peptides, Cyclic; Snake Venoms

2004

Other Studies

13 other study(ies) available for cilengitide and Angiogenesis, Pathologic

ArticleYear
Computational modeling of synergistic interaction between αVβ3 integrin and VEGFR2 in endothelial cells: Implications for the mechanism of action of angiogenesis-modulating integrin-binding peptides.
    Journal of theoretical biology, 2018, 10-14, Volume: 455

    Topics: Autoantigens; Collagen Type IV; Endothelial Cells; Humans; Integrin alphaVbeta3; Models, Biological; Neoplasm Proteins; Neoplasms; Neovascularization, Pathologic; Signal Transduction; Snake Venoms; Vascular Endothelial Growth Factor Receptor-2

2018
Molecular imaging of tumor-associated angiogenesis using a novel magnetic resonance imaging contrast agent targeting αvβ 3 integrin.
    Annals of surgical oncology, 2014, Volume: 21, Issue:6

    Topics: Animals; Colorectal Neoplasms; Contrast Media; Coordination Complexes; Feasibility Studies; Heterocyclic Compounds; HT29 Cells; Humans; Integrin alphaVbeta3; Magnetic Resonance Imaging; Mice; Mice, Nude; Molecular Imaging; Molecular Probes; Muscle, Skeletal; Neovascularization, Pathologic; Organometallic Compounds; Peptides, Cyclic; Snake Venoms

2014
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells.
    Blood, 2015, Jan-29, Volume: 125, Issue:5

    Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Integrin alphaVbeta3; Jurkat Cells; Lymphoma, T-Cell; Male; Mice; Mice, SCID; Neoplasm Transplantation; Neovascularization, Pathologic; RNA, Small Interfering; Signal Transduction; Snake Venoms; T-Lymphocytes; Thyroid Hormones; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A

2015
Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread.
    Cancer cell, 2015, Jan-12, Volume: 27, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Lewis Lung; Cell Line, Tumor; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Lung; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neovascularization, Pathologic; Pancreas; Pancreatic Neoplasms; Snake Venoms; Verapamil

2015
CANCER. Tumor angiogenesis, from foe to friend.
    Science (New York, N.Y.), 2015, Aug-14, Volume: 349, Issue:6249

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Hypoxia; Humans; Neoplasm Recurrence, Local; Neoplasms; Neovascularization, Pathologic; Snake Venoms

2015
Will integrin inhibitors have proangiogenic effects in the clinic?
    Nature medicine, 2009, Volume: 15, Issue:7

    Topics: Animals; Glioblastoma; Humans; Integrins; Neovascularization, Pathologic; Snake Venoms

2009
Radiation-induced modifications of the tumor microenvironment promote metastasis.
    Bulletin du cancer, 2011, Volume: 98, Issue:6

    Topics: Angiogenesis Inhibitors; Cell Hypoxia; Cell Movement; Cell Proliferation; Cysteine-Rich Protein 61; Disease Progression; Endothelial Cells; Humans; Microvessels; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Neovascularization, Pathologic; Receptors, Vitronectin; Snake Venoms; Tumor Microenvironment

2011
Cilengitide affects tumor compartment, vascularization and microenvironment in experimental bone metastases as shown by longitudinal ¹⁸F-FDG PET and gene expression analysis.
    Journal of cancer research and clinical oncology, 2013, Volume: 139, Issue:4

    Topics: Animals; Biomarkers, Tumor; Bone Neoplasms; Breast Neoplasms; Female; Fluorodeoxyglucose F18; Gene Expression Profiling; Humans; Integrin alphaVbeta3; Longitudinal Studies; Male; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Nude; Real-Time Polymerase Chain Reaction; Receptors, Vitronectin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Snake Venoms; Tumor Cells, Cultured; Tumor Microenvironment

2013
Combination therapy of cilengitide with belotecan against experimental glioblastoma.
    International journal of cancer, 2013, Aug-01, Volume: 133, Issue:3

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Glioblastoma; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Snake Venoms; Topoisomerase I Inhibitors; Xenograft Model Antitumor Assays

2013
Micro-MRI at 11.7 T of a murine brain tumor model using delayed contrast enhancement.
    Molecular imaging, 2003, Volume: 2, Issue:3

    Topics: Anatomy, Cross-Sectional; Animals; Brain Neoplasms; Cell Line, Tumor; Contrast Media; Feasibility Studies; Female; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Injections, Intraperitoneal; Integrins; Magnetic Resonance Imaging; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Peptides, Cyclic; Radiographic Image Enhancement; Snake Venoms; Time Factors; Transplantation, Heterologous

2003
alphav beta 3 and alphav beta 5 integrin antagonists inhibit angiogenesis in vitro.
    Angiogenesis, 2003, Volume: 6, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Biological Assay; Cattle; Cell Adhesion; Cell Culture Techniques; Cell Differentiation; Cell Movement; Cloning, Molecular; Collagen; Endothelium, Vascular; Fibrin; Fibroblast Growth Factor 2; Humans; Integrin alphaVbeta3; Integrins; Neovascularization, Pathologic; Neovascularization, Physiologic; Peptide Fragments; Peptides, Cyclic; Protein Structure, Tertiary; Receptors, Vitronectin; Snake Venoms; Vascular Endothelial Growth Factor A

2003
Effect of the angiogenesis inhibitor Cilengitide (EMD 121974) on glioblastoma growth in nude mice.
    Neurosurgery, 2006, Volume: 59, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Female; Glioblastoma; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Snake Venoms; Treatment Outcome

2006
Synergy between an antiangiogenic integrin alphav antagonist and an antibody-cytokine fusion protein eradicates spontaneous tumor metastases.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Feb-16, Volume: 96, Issue:4

    Topics: Animals; Antigens, CD; Colonic Neoplasms; Humans; Immunotherapy; Immunotoxins; Integrin alphaV; Interleukin-2; Melanoma, Experimental; Mice; Neoplasm Metastasis; Neovascularization, Pathologic; Neuroblastoma; Peptides, Cyclic; Receptors, Vitronectin; Recombinant Fusion Proteins; Snake Venoms; Tumor Cells, Cultured

1999