cilastatin has been researched along with Bacterial Disease in 275 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 148 (53.82) | 18.7374 |
| 1990's | 88 (32.00) | 18.2507 |
| 2000's | 23 (8.36) | 29.6817 |
| 2010's | 12 (4.36) | 24.3611 |
| 2020's | 4 (1.45) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, X; Chang, C; Qiao, W; Wang, Q; Zhang, X | 1 |
| Fernández Martínez, AM | 1 |
| Huang, HH; Liang, KW; Tsao, TF; Tyan, YS; Wang, B; Wang, PH | 1 |
| Anoushiravani, A; Farsad, K; Gabr, A; Horikawa, M; Jahangiri, Y; Kumagai, K; Li, J; Uchida, B; Yamada, K | 1 |
| Mady, FM; Shaaban, MI; Shaker, MA | 1 |
| Agudelo, M; Rodriguez, CA; Vesga, O; Zuluaga, AF | 1 |
| Igarashi, Y; Inui, K; Ohara, H; Ryozawa, S; Tazuma, S; Tsuyuguchi, T | 1 |
| Decosterd, LA; Eggimann, P; Fournier, A; Marchetti, O; Pagani, JL; Pannatier, A; Que, YA; Revelly, JP; Voirol, P | 1 |
| Brown, ML; Kartsonis, NA; Lala, M; Losada, MC; Lucasti, C; McLeroth, P; Paschke, A; Pedley, A; Rizk, ML; Sandesc, D; Vasile, L; Venskutonis, D | 1 |
| Brophy, GM; Hoffman, J; Trimble, J | 1 |
| Erdem, E; Gulec, SG; Kebudi, R; Vural, S; Yildirmak, Y | 1 |
| Bayram, H; Dalay, C; Dalkiran, A; Saltoglu, N; Sert, M; Tasova, Y; Tetiker, T | 1 |
| Piyasirisilp, S; Premprawat, W; Thamlikitkul, V | 1 |
| Bi, J; Chen, X; Chen, Z; Cooper, A; Leng, X; Li, R; Liu, D; Ma, X; Maroko, R; Quan, Z; Wei, J; Wu, J; Wu, Z; Yan, L; Yu, Y; Zhang, Y | 1 |
| Huang, A; Huang, W; Jia, B; Li, C; Lu, P; Wu, G; Zhang, G; Zhang, W; Zhou, X | 1 |
| Cox, JC; Drachman, DA; Hibbard, ML; Kopelman, TR; Maly, TJ; Matthews, MR; O'Neill, PJ; Quan, AN; Vail, SJ | 1 |
| Chuang, YC; Cooper, CA; Dartois, N; Datsenko, O; Dukart, G; Dzyublik, O; Freire, AT; Gandjini, H; Glumcher, F; Kim, MJ; Korth-Bradley, JM; Maroko, RT; Melnyk, V | 1 |
| Pietroski, N; Schlossberg, D | 1 |
| Butivshchenko, IA; Goriunov, SV; Il'ianina, AA; Mikhal'skiĭ, VV; Polikarpova, SV; Rog, AA; Romashov, DV | 1 |
| Giller, RH; Nelson, WK; Quinones, R; Rayback, PA | 1 |
| Araake, M; Hara, T; Watabe, H | 1 |
| Inoue, M; Kaku, M; Nasu, M; Sagawa, K; Yokoyama, T | 1 |
| Brink, AJ; Feldman, C; Grolman, DC; Muckart, D; Pretorius, J; Richards, GA; Senekal, M; Sieling, W | 1 |
| Drusano, GL; Lomaestro, BM | 1 |
| Barie, PS; Dellinger, EP; Grasela, TH; Rotstein, OD; Walawander, CA | 1 |
| Campbell, HE; Edwards, SJ; Emmas, CE | 1 |
| Babinchak, T; Dartois, N; Ellis-Grosse, E; Loh, E; Rose, GM | 1 |
| Babinchak, T; Campos, M; Ellis-Grosse, EJ; Loh, E; Oliva, ME; Pasternak, J; Rekha, A; Rose, GM; Yellin, A | 1 |
| Angio, LG; D'Ambrosio, FP; Tigano, F | 1 |
| Altucci, P; Cristiano, P; Iovene, MR; Lobello, R; Morelli, G; Simioli, F | 1 |
| Amato, G; Bariffi, F; Giacomelli, P; Nani, E; Sanduzzi, A | 1 |
| Heilmann, L; Hoynacki, B | 1 |
| Anagnostopoulos, A; Fassas, A; Hadjikyrkou, M; Kontodimou, A; Papageorgiou, T; Proya, E | 1 |
| Campbell, HE; Edwards, SJ; Plumb, JM | 1 |
| Kuti, JL; Nicolau, DP; Ong, CT | 1 |
| Bille, J; Bugnon, D; Cotting, J; Décosterd, L; Giannoni, E; Majcherczyk, P; Moessinger, A; Moreillon, P; Zanetti, G | 1 |
| Ha, JR; Kim, HG; Kim, J; Kim, JG; Lee, DG; Lee, JM; Lee, SH; Oh, SW | 1 |
| Belágyi, T; Bengmark, S; Oláh, A; Pótó, L; Romics, L | 1 |
| Caviezel, A; Garbino, J; Lew, D; Matulionyte, R; Morel, P; Uckay, I; Villiger, P | 1 |
| Katsube, T; Yamano, Y; Yano, Y | 1 |
| Baumgartner, JD; Glauser, MP | 1 |
| Freimer, EH; Hollstein, M; Raeder, R; Ribner, BS | 1 |
| Aldridge, KE; Dickenson, G; Gutterman, D; Hoffman, T; Janney, A; Marier, RL; McCloskey, RV; Sanders, CV | 1 |
| Calandra, GB; Grad, C; Hesney, M | 1 |
| Barza, M | 2 |
| Ishibashi, T; Okada, H; Omori, S; Sasada, M; Sawada, H; Suzuki, T; Tajima, M; Yamamoto, K; Yasuda, N; Yumoto, Y | 1 |
| Cox, CE; Geckler, RW; Holloway, WJ | 1 |
| Fanta, J; Felbr, O; Lochmann, O; Pelák, Z; Vyhnánek, F | 1 |
| Geckler, RW; Nichols, RL; Smith, JW; Wilson, SE | 1 |
| Anséhn, S; Bäckstrand, B; Bergman, L; Brismar, B; Lindgren, V; Malmborg, AS; Mentzing, LO; Nyström, PO; Skau, T; Tunevall, G | 1 |
| Fujisaki, T; Ikeda, K; Katsuno, M; Kozuru, M; Murakawa, M; Niho, Y; Okamura, T; Sawae, Y; Teshima, T; Uike, N | 1 |
| Chimura, T; Matsuo, M; Numazaki, M; Ogawa, T; Saitou, N; Yokoyama, Y | 1 |
| Chimura, T; Matsuo, M; Ogawa, T; Yokoyama, Y | 1 |
| Freeman, DV; Gibbons, GW; Grayson, ML; Habershaw, GM; Karchmer, AW; Levin, E; Pomposelli, FB; Rosenblum, BI | 1 |
| Nasonov, VN; Nekhorosheva, AG; Savitskaia, KI; Shanina, AG | 1 |
| Cakmakci, M; Christen, D; Geroulanos, S; Roggo, A; Schilling, J; Stern, A | 1 |
| Leu, HS; Wu, JL | 1 |
| Casewell, M; Fagan, E; Gimson, A; Philpott-Howard, J; Rolando, N; Sahathevan, M; Westaby, D; Williams, R | 1 |
| de Groot, HG; Hustinx, PA; Lampe, AS; Oosterwijk, WM | 1 |
| Fujita, K; Hatae, Y; Kon-No, M; Nagashima, T; Nakadate, H; Suzuki, Y; Takahashi, Y; Takase, A; Takeda, T; Wagatsuma, Y | 1 |
| Iwaki, H; Kitagishi, H; Mantani, Y; Maruyama, J; Maruyama, K; Matsushima, T; Nakaji, M; Sakata, I; Takahashi, H; Yoshinobu, H | 1 |
| Horiike, S; Kashima, K; Kuzuyama, Y; Misawa, S; Nakai, H; Seriu, T; Takashima, T; Tanaka, S; Taniwaki, M; Tsuda, S | 1 |
| Alhava, E; Haapiainen, R; Havia, T; Kivilaakso, E; Laitinen, S; Matikainen, M; Miettinen, P; Niinikoski, J; Pääkkönen, M | 1 |
| Eklund, AE; Nord, CE | 1 |
| Fujii, Y; Hiroshige, Y; Inoue, Y; Kaku, K; Kaneko, T | 1 |
| Cravarezza, P; Romanelli, G | 1 |
| Diwok, K; Hamacher, J; Kohl, FV; Lichey, J; Lode, H; Vogel, F; Wendel, H | 1 |
| Geroulanos, SJ | 1 |
| Gannon, P; Mucciardi, N; Sesin, GP | 1 |
| Balfour, JA; Brogden, RN; Bryson, HM | 1 |
| Colardyn, F; Faulkner, KL | 1 |
| Bohnen, J; Christou, NV; Potvin, M; Rotstein, O; Turgeon, P; Wassef, R | 1 |
| Akerlund, JE; Andåker, L; Angerås, M; Bäckstrand, B; Bång, H; Brismar, B; Darle, N; Eklund, AE; Falk, A; Gasslander, T; Gustafsson, PO; Hagelbäck, A; Johansson, C; Kasholm-Tengve, B; Nord, CE; Nyström, PO; Olsson-Liljequist, B; Sjöstedt, S; Skau, T; Törnqvist, A; Tunevall, G | 1 |
| Angerås, MH; Darle, N; Ekelund, M; Engström, L; Hamnström, K; Holme, JB; Takala, J; Viste, A | 1 |
| Gibbons, GW; Grayson, ML; Karchmer, AW; McKinnon, PS; Paladino, JA | 1 |
| Akashi, K; Asayama, R; Gondo, H; Goto, T; Harada, N; Hayashi, S; Hisano, S; Ishikura, H; Kawasaki, C; Kozuru, M; Kumakawa, M; Morioka, E; Muta, K; Nakajima, H; Niho, Y; Nishimura, J; Okamura, T; Sawae, Y; Shibuya, T; Suehiro, Y; Suematsu, E; Uike, N; Yamasaki, K; Yamashita, S; Yufu, Y | 1 |
| Chung, KC; Gill, MA; Moon, YS | 1 |
| Craig, WA | 1 |
| Tonelli, F | 1 |
| Bacci, S; Bosi, A; Fanci, R; Guidi, S; Laszlo, D; Rossi Ferrini, P; Saccardi, R; Vannucchi, AM | 1 |
| Li, J; Liu, S; Wang, D; Xu, S | 1 |
| Cainzos Fernández, M | 1 |
| Basoli, A; Mazzocchi, P; Meli, EZ; Speranza, V | 1 |
| Faulkner, K; Wilson, SE | 1 |
| Colombo, M; Crosignani, P; Di Stefano, F; Facchini, V; Irato, S; Maggioni, P; Mancuso, S; Massobrio, M; Melis, GB | 1 |
| Bur, F; Donahue, PE; Luke, DR; Mintz, SJ; Smith, DL; Yellin, AE | 1 |
| Crespo, M; Marcén, R; Ortuño, J; Rivera, M; Teruel, JL | 1 |
| Bryce, EA; Frighetto, LO; Jewesson, PJ; Marra, CA; Marra, FO; Reynolds, RP; Sleigh, KM; Stiver, HG | 1 |
| Benfield, P; Chrisp, P | 1 |
| Badía, X; Brosa, M; Tellado, JM | 1 |
| Paladino, JA; Solomkin, JS; Walters, DJ | 1 |
| Bennion, RS; Christou, NV; Dellinger, EP; Pak, R; Rotstein, OD; Solomkin, JS; Tack, K; Wilson, SE | 1 |
| Verwaest, C | 1 |
| Daschner, F; Dietrich, ES; Ebner, W; Schubert, B | 1 |
| Masaoka, T | 1 |
| Biglino, A; Bonasso, M; Gioannini, P | 1 |
| Bäckstrand, B; Bergman, L; Brismar, B; Kihlström, E; Malmborg, AS; Mentzing, LO; Nyström, PO; Skau, T; Tunevall, G; Wretlind, B | 1 |
| Itoh, M; Nakano, T; Sakurai, M | 1 |
| Aoyama, S; Banzai, M; Chimura, T; Kawachiya, S; Matsuo, M; Miyata, R; Nara, N; Ogawa, T; Yamazaki, K; Yokoyama, Y | 1 |
| Dinsmoor, MJ | 1 |
| Andrade, R; Cabello, M; Clavijo, E; Lucena, M; Queipo de Llano, E | 1 |
| Bosseray, A; Brion, JP; Hollard, D; Michallet, M; Micoud, M; Nicolini, F; Stahl, JP | 1 |
| Heikkinen, E; Seppänen, J; Uhari, M | 1 |
| Asano, Y; Harada, M; Kozuru, M; Murakawa, M; Niho, Y; Okamura, T; Sawae, Y; Shibuya, T; Taniguchi, S; Toyoshima, T | 1 |
| Björkholm, MJ; Engervall, PA; Günther, GC; Stiernstedt, GT | 1 |
| Doko, F; Hirabayashi, K; Kawai, J; Kojima, Y; Matsuda, S; Oh, K; Okada, E; Tateno, M | 1 |
| Banzai, M; Chimura, T; Kanasugi, H; Kihara, K; Matsuo, M; Miyata, R; Oda, T; Takahashi, H; Yamazaki, K; Yokoyama, Y | 1 |
| Bengel, D; Przechera, M; Risler, T | 1 |
| Fukuoka, M; Kusunoki, Y; Masuda, N; Matsui, K; Takada, M | 1 |
| Bellantone, R; Brisinda, G; Crucitti, F; Doglietto, GB; Pacelli, F | 1 |
| D'Antona, R; Macrina, E; Verre, M | 1 |
| Graziani, AL; MacGregor, RR; Sexton, DJ; Tobey, LE; Wlodaver, CG; Yangco, BG | 1 |
| Calandra, GB; Garau, J | 1 |
| MacGregor, RR | 1 |
| Hirabayashi, N; Hotta, T; Kato, Y; Kodera, Y; Mizuno, H; Morishima, Y; Morishita, Y; Saito, H; Suzuki, H; Tanaka, M | 1 |
| Jacobus, NV; Petersen, PJ; Testa, RT; Weiss, WJ | 1 |
| Fukuhara, H; Irabu, Y; Kakazu, T; Kaneshima, H; Kitukawa, K; Kusano, N; Nakamura, H; Saito, A; Shigeno, Y; Shimozi, K | 1 |
| Murakami, T; Nakagawa, H; Nakai, H; Nishida, K; Nishigaki, H; Okuda, T; Seryu, S; Takashima, T; Tanaka, S; Tsuda, S | 1 |
| Aizawa, T; Furuta, S; Ichikawa, S; Koike, Y; Maruyama, D; Nagata, A; Nishizawa, K; Saito, H; Yoda, H; Yoshizawa, S | 1 |
| Abel, SR; Guba, EA | 1 |
| Bagshaw, PF; Bremner, JM; Chin, MJ | 1 |
| Fujita, J; Higuchi, K; Irino, S; Nakano, M; Negayama, K; Yamaji, Y | 1 |
| Inderlied, CB; Kim, KS; Mason, WH; Ross, LA; Wong, VK; Wright, HT | 1 |
| Cristiano, P; Iovene, MR; Lobello, R; Pezza, M; Raucci, G; Simioli, F | 1 |
| Deguchi, K; Kageyama, S; Katayama, N; Kobayashi, T; Minami, N; Nishikawa, M; Shirakawa, S; Tsukada, T | 1 |
| Leroy, J | 1 |
| Bouletreau, P | 1 |
| Gouin, F | 1 |
| Espinouse, D | 1 |
| Armengaud, M | 1 |
| Antonucci, G; Armignacco, O; Bordi, E; Bove, G; D'Amato, C; De Carli, G; De Mori, P; Rosci, MA; Visco, G | 1 |
| Buchmann, P; Christen, D; Geroulanos, S; Stern, A | 1 |
| Chan, TK; Chau, PY; Chiu, E; Lam, WK; Liang, R; Todd, D; Yung, R | 1 |
| Ikeda, Y; Kobayashi, M; Kodera, Y; Mitomo, Y; Naito, K; Oguri, T; Ohara, K; Ohno, R; Okumura, M; Tanaka, M | 1 |
| Inoue, M; Kawa, K; Konishi, S; Naya, Y; Nishida, M; Sako, M; Yabuuchi, H | 1 |
| Adam, D; Bauernfeind, A; Hönig, E; Naber, KG | 1 |
| Böhler, J; Fecht, H; Keller, E; Schollmeyer, P | 1 |
| Carrella, G; Donini, I; Intini, S; Marzola, R; Sortini, A | 1 |
| Arciello, MT; Conte, M; Coppola, MG; Covelli, B; De Sena, R; Fiorentino, F; Galderisi, P; Iadanza, A; Manzillo, E; Postiglione, A | 1 |
| Roach, AC | 1 |
| Bucaneve, G; Del Favero, A; Menichetti, F; Minotti, V; Pasticci, MB; Tonato, M | 1 |
| Aihara, M; Chiba, Y; Haga, Y; Ogasawara, H; Sakata, Y; Sasaki, D; Sawada, Y; Suzuki, A; Takemori, H; Yoshida, Y | 1 |
| Fujimoto, T; Kawakami, A; Koga, T; Motohiro, T; Oda, K; Sakata, Y; Shimada, Y; Tanaka, K; Tominaga, K; Tomita, S | 1 |
| Akasaka, K; Kageyama, T; Kitani, T; Nasu, K; Nin, T; Ohyabu, H; Sannomiya, Y; Tatsumi, N; Tominaga, N; Yonezawa, T | 1 |
| Fujii, R; Fujita, K; Hashira, S; Inyaku, F; Maruyama, S; Nakazawa, S; Sakata, H; Sato, H; Tajima, T; Yoshioka, H | 1 |
| Baron, S; Bégué, P; Challier, P; Fontaine, JL; Lasfargues, G; Quinet, B | 1 |
| Ahonkhai, VI; Brown, KR; Cyhan, GM; Wilson, SE | 1 |
| Overturf, GD | 1 |
| Cristiano, P | 1 |
| Fujii, R; Hashira, S; Tajima, T | 1 |
| Iwai, N; Kasai, K; Miyazu, M; Nakamura, H; Taneda, Y | 1 |
| Agaliotis, D; Ezzeddine, H; Gala, JL; Gigi, J; Michaux, JL; Vandercam, B; Wauters, G | 1 |
| Haruta, T; Kobayashi, Y; Kubo, K; Kuroki, S; Okura, KE; Yamamoto, H; Yamaoka, K | 1 |
| Kanat, IO; Pantig-Felix, L; Ross, CD | 1 |
| Akita, H; Ishizuka, Y; Iwata, S; Oikawa, T; Saito, N; Sato, Y; Sunakawa, K | 1 |
| Chimura, T; Fujimoto, S; Ishikawa, M; Makinoda, S; Matsuda, S; Oh, K; Shimizu, T; Soma, A; Suzuki, M; Takada, H | 1 |
| Cho, N; Fukunaga, K; Kobayashi, I; Kunii, K; Tezuka, K | 1 |
| Brand, J; Mayer, M; Opferkuch, W; Schlenkhoff, D | 1 |
| Lenhart, FP; Ruckdeschel, G; Unertl, K | 1 |
| Conarro, PA; Culbertson, GR; Mason, AD; McManus, AT; McManus, WF; Pruitt, BA | 1 |
| Fridrik, MA; Grafinger-Witt, E; Leisch, F; Wahl, G | 1 |
| Chikaoka, H; Kamigaki, M; Koido, R; Matsumoto, K; Nakanishi, Y; Nakazawa, S; Narita, A; Sato, H; Suzuki, H | 1 |
| Fujita, K; Kaeriyama, M; Kakehashi, H; Maruyama, S; Mori, Y; Murono, K; Oka, T; Sakata, H; Sasaki, N; Yoshioka, H | 1 |
| Hori, M; Joh, K; Sugita, M; Toyonaga, Y | 1 |
| Azagami, S; Kusumoto, Y; Nakamura, M; Oikawa, T; Osano, M; Shirai, Y; Shiro, H | 1 |
| Kamiya, Y; Murata, Y; Narita, H; Suzuki, T; Tsuruga, N; Yura, J | 1 |
| Haruta, T; Kanamoto, T; Kobayashi, Y; Okura, KE | 1 |
| Chimura, T; Hirayama, T; Matsuo, M; Morisaki, N | 1 |
| Matsuda, S; Oh, K; Suzuki, M | 1 |
| Ishikawa, M; Kitamura, S; Mizukami, A; Shimizu, T; Soma, A; Takada, H | 1 |
| Tateno, M | 2 |
| Kanao, M; Okada, H; Yamamoto, T; Yasuda, J | 1 |
| Hayasaki, M; Ito, K; Izumi, K; Takagi, H; Tamaya, T | 1 |
| Hirabayashi, K; Okada, E | 2 |
| Creger, RJ; Danziger, LH; Hau, T; Shwed, JA; Stellato, TA | 1 |
| Barza, M; Gorbach, SL; Hackford, AW; Reinhold, RB; Tally, FP | 1 |
| Lipman, B; Neu, HC | 1 |
| Brown, KR; Calandra, GB; Ricci, FM; Wang, C | 1 |
| Calandra, G; Carrigan, J; Guess, H; Lydick, E; Weiss, L | 1 |
| Alvarez, ME; Bodey, GP; Elting, L; Fainstein, V; Jones, P; Rolston, K | 1 |
| Broze, B; de Lame, PA; De Mees, J; Droissart, R; Nolens, VP; Staudt, JP; Verstraeten, ME | 1 |
| Borner, K; Höffken, G; Lode, H; Wagner, J; Wiley, R | 1 |
| Mashimo, K | 1 |
| Buchmann, P; Christen, D; Geroulanos, S | 1 |
| Del Valle, J; Noriega, AR; Otero, JR; Revilla, AP; Sanz, F | 1 |
| Cook, T; Pappas, F; Wang, C | 2 |
| Jacobsen, CA; Nalin, DR | 1 |
| Aziz, MA; Hart, CB; Nalin, DR; Shih, WJ | 1 |
| Johnson, E; Kennedy, RH; Leaper, DJ; Roberts, N; Sutton, A | 1 |
| Andrien, F; Anniko, M; Baudrihaye, M; Bow, E; Burman, LA; Louie, T; Norberg, B; Norrby, SR; Runde, V; Vandercam, B | 1 |
| Avery, D; Kennedy, R; Leaper, D; Leow, C; Thomas, W | 1 |
| Bielawska, C; Deaney, NB; Kelsey, MC; Rai, G; Smith, MD | 1 |
| Black, D; Kirby, WM; Kwok, K; Miller, S; Mortimer, J | 1 |
| Bland, JA; Gibson, GA; MacGregor, RR | 1 |
| Albrecht, LM; Rybak, MJ | 1 |
| Gilligan, PH; Long, SS; Welkon, CJ | 1 |
| Hanaoka, J; Maruhashi, T; Minagawa, Y; Oomomo, Y; Sasagawa, S; Takahashi, T; Takeuchi, S; Tokunaga, A; Yuzawa, H | 1 |
| Arai, K; Hogaki, M; Iwase, H; Seto, H | 1 |
| Cho, N; Fukunaga, K; Kunii, K | 1 |
| Akagi, T; Fujiwara, A; Hara, T; Iwasaki, K; Kudo, Y; Masaoka, T; Matsuo, M; Naito, H; Urabe, T | 1 |
| Doko, F | 1 |
| Demise, M; Iwaki, M; Makinoda, S; Okubo, H; Sato, H; Shinkai, N; Tabata, M; Takaoka, H; Yamaguchi, T | 1 |
| Chimura, T; Matsuo, M; Morisaki, N | 1 |
| Ikeno, N; Muraguchi, K; Murai, H; Nakakuki, M; Okamura, K; Saito, A; Takahashi, K; Wakisaka, T; Watanabe, M; Yamada, K | 1 |
| Hachiya, S; Imagawa, N; Koike, K; Morimoto, O; Obata, I; Yokoyama, S | 1 |
| Hayasaki, M; Ito, K; Ito, T; Matsunami, K; Noda, K; Takada, Y | 1 |
| Hayashi, S; Lin, BL; Nakamura, H | 1 |
| Kanao, M; Okada, H; Tomioka, M; Yamamoto, T; Yasuda, J | 1 |
| Fujimoto, H; Ikeda, K; Shirakawa, K; Taguchi, S; Yamamoto, K | 1 |
| Horii, T; Noda, K | 1 |
| Akagi, T; Fukagawa, R; Hatase, T; Hirai, H; Kato, T; Kawano, K; Ohokura, N; Tsunawaki, A | 1 |
| Hata, T; Kumagaya, J; Takamura, S; Yamabe, T | 1 |
| Fujita, K; Inyaku, F; Kakehashi, H; Maruyama, S; Murono, K; Ohmi, H; Sakata, H; Sanae, N; Yoshioka, H | 1 |
| Horiguchi, S; Kusunoki, Y; Nagamatsu, I; Takase, A; Tateno, Y; Wagatsuma, Y | 1 |
| Izumi, Y; Nagata, K; Ohnishi, A; Yokoyama, M | 1 |
| Hirosawa, H; Hoshina, H; Ichihashi, H; Morikawa, Y | 1 |
| Hori, M; Sugita, M; Takahashi, T; Toyonaga, Y; Tsuda, T | 1 |
| Arimasu, O; Fujii, R; Izumi, K; Kobayashi, M; Meguro, H; Shiraishi, H | 1 |
| Chikaoka, H; Kamigaki, M; Koido, R; Matsumoto, K; Nakada, Y; Nakazawa, S; Narita, A; Sato, H; Suzuki, H | 1 |
| Kusumoto, Y; Oikawa, T; Osano, M; Shiro, H | 1 |
| Hachimori, K; Kaneda, K; Minamitani, M | 1 |
| Hakamada, S; Hayakawa, F; Kuno, K; Miyachi, Y; Nakashima, S; Nakashima, T | 1 |
| Inokuma, K; Iwai, N; Katayama, M; Miyazu, M; Nakamura, H; Shibata, M; Taneda, Y | 1 |
| Nishimura, T; Tabuki, K; Takagi, M; Takashima, T | 1 |
| Arimasu, O; Fujii, R; Fujita, K; Inyaku, F; Maruyama, S; Meguro, H; Nagamatsu, I; Takase, A; Wagatsuma, Y; Yoshioka, H | 1 |
| Fujimoto, T; Koga, T; Motohiro, T; Nishiyama, T; Shimada, Y; Suzuki, K; Tominaga, K; Tomita, S; Toyoda, O; Yamashita, F | 1 |
| Sakurai, M | 1 |
| Reutter, FW | 1 |
| Alvarez, ME; Bodey, GP; Fainstein, V; Jones, P; Rolston, K; Steelhammer, L | 1 |
| Andremont, A; Baruchel, A; Hartmann, O; Tancrède, C | 1 |
| Aziz, M; Brown, KR; Calandra, GB; Wang, C | 1 |
| Casagrán, A; Garau, J; Matas, E; Sánchez, C | 1 |
| Brown, KR; Calandra, GB; Raupp, W | 1 |
| Baron, S; Bégué, PC; Challier, P; Fontaine, JL; Lasfargues, G | 1 |
| Keller, CA; Ramirez, C; Villavicencio, J | 1 |
| Loch, H; Wenzel, M | 1 |
| Hasegawa, Y; Ichinoe, K; Maeda, Y; Makinoda, S; Matsuda, S; Ninomiya, K; Sato, H; Shimizu, T; Suzuki, M | 1 |
| Alvarez, ME; Bodey, GP; Fainstein, V; Jones, PG; Rolston, KV; Steelhammer, L | 1 |
| Satoh, K; Watanabe, A | 1 |
| Ishizuka, Y; Kawai, N; Saito, N; Sunakawa, K | 1 |
| Aguilaniu, F; Bru, JP; Chavanet, P; Croize, J; Mercatello, A; Micoud, M; Portier, H; Robert, D; Stahl, JP | 1 |
| Freij, BJ; Kusmiesz, H; Nelson, JD; Shelton, S | 1 |
| Gever, LN | 1 |
| Breddin, HK; Henkel-Bussmann, M; Shah, PM; Ziemen, M | 1 |
| Shah, PM | 1 |
| Fischer, M; Voeckl, J | 1 |
| Aebert, H; Bunzendahl, H; Hünefeld, G; Weissbrodt, H | 1 |
| Hollandt, H; Schier, H; Valesky, A; Wenk, H | 1 |
| Forst, H; Lenhart, FP; Ruckdeschel, G; Unertl, K | 1 |
| Stene, R | 1 |
| Bremner, DA; Downey, D; Ellis-Pegler, RB | 1 |
| Gentry, LO; MacGregor, RR | 1 |
| Duma, RJ; Gebhart, RL; Groschel, DH; Mandell, GL; Palmer, DL; Salata, RA; Scheld, WM; Wade, BH; Wenzel, RP | 1 |
| Hilton, E; Iannini, GM; Iannini, PB; Kunkel, MJ | 1 |
| Gentry, LO | 1 |
| Berkeley, AS; Freedman, K; Hirsch, J; Ledger, WJ | 1 |
| Fisher, MA; Gibson, GA; MacGregor, RR; Zajac, BA | 1 |
| Bailie, GR; Crossley, KB; Rotschafer, JC | 1 |
| Decazes, JM; Meulemans, A; Modai, J; Vittecoq, D | 1 |
| Brown, KR; Calandra, GB; Hesney, M | 1 |
| Fass, RJ; Freimer, EH; McCloskey, RV | 1 |
| Marier, RL | 1 |
| Gorbach, SL; Tally, FP | 1 |
| Alexander, JW; Fant, WK; Rivera, JO; Solomkin, JS | 1 |
| Alpert, G; Bloh, AM; Campos, JM; Connor, E; Dagan, R; Plotkin, SA; Powell, KR | 1 |
| Lyon, JA | 1 |
20 review(s) available for cilastatin and Bacterial Disease
| Article | Year |
|---|---|
Imipenem cilastatin sodium-associated thrombocytopenia in an older patient: A case report and literature review.
Topics: Aged; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Humans; Imipenem; Male; Thienamycins; Thrombocytopenia | 2022 |
Safety of imipenem/cilastatin in neurocritical care patients.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Critical Care; Drug Combinations; Humans; Imipenem; Nervous System Diseases; Protease Inhibitors | 2009 |
Appropriate use of the carbapenems.
Topics: Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Carbapenems; Cilastatin; Community-Acquired Infections; Cross Infection; Drug Resistance, Bacterial; Drug Utilization; Ertapenem; Humans; Imipenem; Lactams; Meropenem; Patient Selection; Pneumonia, Bacterial; Practice Patterns, Physicians'; Protease Inhibitors; South Africa; Surgical Wound Infection; Thienamycins; Urinary Tract Infections | 2004 |
Systematic review comparing meropenem with imipenem plus cilastatin in the treatment of severe infections.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Humans; Imipenem; Meropenem; Protease Inhibitors; Randomized Controlled Trials as Topic; Risk; Thienamycins | 2005 |
Imipenem/cilastatin: an update of its antibacterial activity, pharmacokinetics and therapeutic efficacy in the treatment of serious infections.
Topics: Bacteria; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Humans; Imipenem | 1996 |
Pharmacokinetics of meropenem in animals, healthy volunteers, and patients.
Topics: Adult; Aged; Animals; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Cilastatin; Drug Therapy, Combination; Humans; Imipenem; Infant; Kidney; Meropenem; Molecular Structure; Protease Inhibitors; Rabbits; Rats; Thienamycins; Urine | 1997 |
The pharmacology of meropenem, a new carbapenem antibiotic.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; Child; Child, Preschool; Cilastatin; Clinical Trials as Topic; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Imipenem; Infant; Infant, Newborn; Kidney; Male; Meropenem; Microbial Sensitivity Tests; Molecular Structure; Renal Insufficiency; Thienamycins | 1997 |
Imipenem/cilastatin: a pharmacoeconomic appraisal of its use in intra-abdominal infections.
Topics: Abdomen; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Drug Utilization; Europe; Forecasting; Formularies as Topic; Health Care Costs; Humans; Imipenem; Length of Stay; Randomized Controlled Trials as Topic; Treatment Outcome; United States | 1992 |
[Evidence-based medicine, health costs and treatment of intra-abdominal infection].
Topics: Abdomen; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Child; Cilastatin; Clinical Trials as Topic; Cost-Benefit Analysis; Double-Blind Method; Drug Costs; Drug Therapy, Combination; Evidence-Based Medicine; Health Care Costs; Hospital Costs; Humans; Imipenem; Meropenem; Middle Aged; Odds Ratio; Prospective Studies; Single-Blind Method; Spain; Thienamycins; Treatment Outcome | 1999 |
Imipenem-cilastatin.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Resistance, Microbial; Female; Genital Diseases, Female; Humans; Imipenem; Pregnancy; Pregnancy Complications, Infectious | 1992 |
Overall clinical utility of the intramuscular preparation of imipenem/cilastatin.
Topics: Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Infusions, Intravenous; Injections, Intramuscular; Male | 1991 |
[An imipenem-cilastatin combination in the treatment of infection at general intensive care units].
Topics: Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Humans; Imipenem; Intensive Care Units; Male; Middle Aged; Multicenter Studies as Topic | 1990 |
Use of imipenem-cilastatin in pediatrics.
Topics: Bacterial Infections; Child; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Humans; Imipenem | 1989 |
Imipenem/cilastatin: its use in the treatment of foot infections in the compromised host.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Drug Combinations; Foot Diseases; Humans; Imipenem; Opportunistic Infections; Thienamycins | 1988 |
Imipenem: a new carbapenem antibiotic.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Drug Combinations; Humans; Imipenem; Thienamycins | 1988 |
The efficacy results and safety profile of imipenem/cilastatin from the clinical research trials.
Topics: Bacterial Infections; Cilastatin; Cyclopropanes; Humans; Imipenem; Thienamycins | 1988 |
[New antimicrobial agent series XXV: imipenem/cilastatin sodium].
Topics: Bacteria; Bacterial Infections; Cilastatin; Cyclopropanes; Drug Combinations; Humans; Imipenem; Thienamycins | 1987 |
Therapy of mixed anaerobic-aerobic infections. Lessons from studies of intra-abdominal sepsis.
Topics: Abdomen; Abscess; Bacteria, Anaerobic; Bacterial Infections; Bacteroides; Cilastatin; Clindamycin; Cyclopropanes; Drug Combinations; Gentamicins; Humans; Imipenem; Thienamycins | 1985 |
Imipenem: first of a new class of beta-lactam antibiotics.
Topics: Animals; Bacteria; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Drug Therapy, Combination; Humans; Imipenem; Kinetics; Microbial Sensitivity Tests; Thienamycins | 1985 |
Imipenem/cilastatin: the first carbapenem antibiotic.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Chemical Phenomena; Chemistry; Cilastatin; Clinical Trials as Topic; Cyclopropanes; Dipeptidases; Humans; Imipenem; Kinetics; Thienamycins | 1985 |
114 trial(s) available for cilastatin and Bacterial Disease
| Article | Year |
|---|---|
Clinical efficacy of intravenous doripenem in patients with acute biliary tract infection: a multicenter, randomized, controlled trial with imipenem/cilastatin as comparator.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Body Temperature; C-Reactive Protein; Carbapenems; Cholangitis; Cholecystitis, Acute; Cilastatin; Cilastatin, Imipenem Drug Combination; Doripenem; Drug Combinations; Female; Humans; Imipenem; Infusions, Intravenous; Male; Middle Aged; Treatment Outcome; Young Adult | 2015 |
Phase 2, Dose-Ranging Study of Relebactam with Imipenem-Cilastatin in Subjects with Complicated Intra-abdominal Infection.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azabicyclo Compounds; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Intraabdominal Infections; Male; Middle Aged; Treatment Outcome; Young Adult | 2016 |
Imipenem-cilastatin versus piperacillin-tazobactam as monotherapy in febrile neutropenia.
Topics: Adolescent; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Fever; Humans; Imipenem; Male; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies | 2010 |
Piperacillin/tazobactam versus imipenem/cilastatin for severe diabetic foot infections: a prospective, randomized clinical trial in a university hospital.
Topics: Adult; Aged; Aged, 80 and over; Amputation, Surgical; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Diabetic Foot; Drug Combinations; Female; Hospitals, University; Humans; Imipenem; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Recurrence; Time Factors; Treatment Outcome | 2010 |
Efficacy and safety of tigecycline monotherapy vs. imipenem/cilastatin in Chinese patients with complicated intra-abdominal infections: a randomized controlled trial.
Topics: Adult; Aged; Anti-Bacterial Agents; Asian People; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Male; Middle Aged; Minocycline; Peritonitis; Tigecycline; Treatment Outcome | 2010 |
A multicenter, randomized controlled clinical study on biapenem and imipenem/cilastatin injection in the treatment of respiratory and urinary tract infections.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Hospitals, Teaching; Humans; Imipenem; Male; Middle Aged; Respiratory Tract Infections; Thienamycins; Urinary Tract Infections; Young Adult | 2010 |
Comparison of tigecycline with imipenem/cilastatin for the treatment of hospital-acquired pneumonia.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Cross Infection; Double-Blind Method; Drug Combinations; Hospital Mortality; Humans; Imipenem; Microbial Sensitivity Tests; Minocycline; Pneumonia; Pneumonia, Ventilator-Associated; Tigecycline; Treatment Outcome | 2010 |
[Efficacy of imipenem-cilastatin in combined therapy of severe anaerobic-aerobic infection of bones and soft tissues].
Topics: Adult; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; Bone Diseases; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Middle Aged; Severity of Illness Index; Soft Tissue Infections | 2002 |
Empiric carbapenem monotherapy in pediatric bone marrow transplant recipients.
Topics: Adolescent; Bacterial Infections; Bone Marrow Transplantation; Carbapenems; Child; Child, Preschool; Cilastatin; Drug Costs; Female; Humans; Imipenem; Male; Meropenem; Postoperative Complications; Prospective Studies; Protease Inhibitors; Thienamycins; Vomiting | 2002 |
The efficacy and safety of tigecycline for the treatment of complicated intra-abdominal infections: analysis of pooled clinical trial data.
Topics: Adult; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Intestinal Diseases; Male; Microbial Sensitivity Tests; Middle Aged; Minocycline; Tigecycline | 2005 |
A multicenter trial of the efficacy and safety of tigecycline versus imipenem/cilastatin in patients with complicated intra-abdominal infections [Study ID Numbers: 3074A1-301-WW; ClinicalTrials.gov Identifier: NCT00081744].
Topics: Abdomen; Adult; Anti-Bacterial Agents; Appendicitis; Bacterial Infections; Cholecystitis; Cilastatin; Cilastatin, Imipenem Drug Combination; Diverticulitis; Double-Blind Method; Drug Combinations; Female; Humans; Imipenem; Intestinal Perforation; Male; Middle Aged; Minocycline; Peptic Ulcer Perforation; Peritonitis; Tigecycline | 2005 |
Synbiotic control of inflammation and infection in severe acute pancreatitis: a prospective, randomized, double blind study.
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Combined Modality Therapy; Dietary Fiber; Dietary Supplements; Double-Blind Method; Drug Combinations; Enteral Nutrition; Female; Humans; Imipenem; Male; Middle Aged; Multiple Organ Failure; Pancreatitis, Acute Necrotizing; Probiotics; Prospective Studies; Survival Rate; Systemic Inflammatory Response Syndrome; Treatment Outcome | 2007 |
A randomized prospective study of cefepime plus metronidazole with imipenem-cilastatin in the treatment of intra-abdominal infections.
Topics: Abdominal Cavity; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; APACHE; Bacterial Infections; Cefepime; Cephalosporins; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Hospitals, University; Humans; Imipenem; Male; Metronidazole; Middle Aged | 2007 |
Imipenem/cilastatin versus gentamicin/clindamycin for treatment of serious bacterial infections. Report from a Scandinavian Study Group.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Clindamycin; Clinical Trials as Topic; Cyclopropanes; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Gentamicins; Humans; Imipenem; Male; Middle Aged; Random Allocation; Thienamycins | 1984 |
Comparative study of imipenem in severe infections.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cefotaxime; Cilastatin; Clinical Trials as Topic; Cyclopropanes; Drug Resistance, Microbial; Female; Humans; Male; Middle Aged; Random Allocation | 1983 |
A randomized study comparing clinical efficacy and safety of thienamycin formamidine (MK0787)/renal dipeptidase inhibitor (MK0791) and cefazolin.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cefazolin; Cilastatin; Clinical Trials as Topic; Cyclopropanes; Dipeptidases; Drug Therapy, Combination; Humans; Imipenem; Kidney; Middle Aged; Random Allocation; Thienamycins | 1983 |
Comparative clinical trial of imipenem-cilastatin (N-formimidoyl-thienamycin-dehydropeptidase inhibitor) and cefazolin.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cefazolin; Cilastatin; Clinical Trials as Topic; Cyclopropanes; Female; Humans; Imipenem; Male; Microbial Sensitivity Tests; Middle Aged; Thienamycins | 1983 |
A multiclinic randomized study of the comparative efficacy, safety and tolerance of imipenem/cilastatin and moxalactam.
Topics: Adult; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cilastatin; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Drug Tolerance; Female; Humans; Imipenem; Male; Microbial Sensitivity Tests; Middle Aged; Moxalactam; Thienamycins | 1984 |
[Effect of a combination treatment using imipenem/cilastatin sodium with G-CSF on infections in neutropenic patients with hematological malignancies].
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Humans; Imipenem; Immunocompromised Host; Male; Middle Aged; Neutropenia | 1995 |
A multicenter comparative study of meropenem and imipenem/cilastatin in the treatment of complicated urinary tract infections in hospitalized patients.
Topics: Bacteria; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Hospitalization; Humans; Imipenem; Infusions, Intravenous; Male; Meropenem; Middle Aged; Prospective Studies; Protease Inhibitors; Thienamycins; Urinary Tract Infections | 1995 |
Meropenem versus imipenem/cilastatin in the treatment of hospitalized patients with skin and soft tissue infections.
Topics: Abscess; Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cellulitis; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Hospitalization; Humans; Imipenem; Infusions, Intravenous; Male; Meropenem; Middle Aged; Prospective Studies; Skin Diseases, Infectious; Soft Tissue Infections; Thienamycins; Ulcer | 1995 |
Meropenem versus imipenem/cilastatin in the treatment of intra-abdominal infections.
Topics: Abdomen; Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Infusions, Intravenous; Male; Meropenem; Middle Aged; Thienamycins | 1995 |
[A comparative study of imipenem/cilastatin sodium BID vs QID in the treatment of infections associated with hematopoietic disorders].
Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Japan; Leukemia; Lymphoma; Male; Middle Aged | 1994 |
[Evaluation of changes in IL-6 in gynecological infections].
Topics: Adult; Bacterial Infections; Biomarkers; C-Reactive Protein; Chorioamnionitis; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Genital Diseases, Female; Humans; Imipenem; Interleukin-6; Middle Aged; Pancreatic Elastase; Pregnancy | 1994 |
[Clinical effects of imipenem/cilastatin sodium on gynecological infections].
Topics: Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Genital Diseases, Female; Humans; Imipenem; Japan; Urinary Tract Infections | 1994 |
Use of ampicillin/sulbactam versus imipenem/cilastatin in the treatment of limb-threatening foot infections in diabetic patients.
Topics: Adult; Ampicillin; Amputation, Surgical; Bacterial Infections; Cilastatin; Combined Modality Therapy; Debridement; Diabetic Foot; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Humans; Imipenem; Osteomyelitis; Sulbactam; Treatment Outcome | 1994 |
Randomized comparative trial of imipenem/cilastatin versus aminoglycoside plus amoxycillin plus clindamycin in the treatment of severe intra- and post-operative infections.
Topics: Aminoglycosides; Amoxicillin; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Clindamycin; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Intraoperative Complications; Male; Middle Aged; Postoperative Complications; Prospective Studies | 1993 |
Infectious sequelae after endoscopic sclerotherapy of oesophageal varices: role of antibiotic prophylaxis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Enterobacter cloacae; Enterobacteriaceae Infections; Escherichia coli Infections; Esophageal and Gastric Varices; Esophageal Diseases; Esophagoscopy; Female; Humans; Imipenem; Male; Middle Aged; Prospective Studies; Sclerotherapy; Staphylococcal Infections; Staphylococcus aureus | 1993 |
Comparison of imipenem/cilastatin with the combination of aztreonam and clindamycin in the treatment of intra-abdominal infections.
Topics: Abdomen; Adolescent; Adult; Aged; Aged, 80 and over; Aztreonam; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Clindamycin; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Middle Aged; Premedication; Prospective Studies; Surgical Wound Infection; Treatment Failure | 1993 |
[A multi-institutional study on the efficacy and toxicity of imipenem/cilastatin sodium in severe infections complicating hematological diseases and cancers in children. Study Group of Infectious Diseases in Pediatric Hematology/Oncology in Hokkaido].
Topics: Adolescent; Bacterial Infections; Child; Child, Preschool; Cilastatin; Drug Therapy, Combination; Female; Humans; Imipenem; Infant; Leukemia; Leukopenia; Male; Neoplasms; Pneumonia; Sepsis | 1993 |
[Clinical study of imipenem/cilastatin sodium in serious infections in critical care medical center].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Child; Child, Preschool; Cilastatin; Drug Therapy, Combination; Emergencies; Humans; Imipenem; Infant; Middle Aged; Wounds and Injuries | 1993 |
Piperacillin/tazobactam versus imipenem/cilastatin in the treatment of intra-abdominal infections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; beta-Lactamase Inhibitors; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Infusions, Intravenous; Male; Middle Aged; Penicillanic Acid; Peritoneal Diseases; Piperacillin; Tazobactam; Treatment Outcome | 1993 |
A randomized multicenter trial of piperacillin/tazobactam versus imipenem/cilastatin in the treatment of severe intra-abdominal infections. Swedish Study Group.
Topics: Abdomen; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; beta-Lactamase Inhibitors; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Injections, Intravenous; Male; Middle Aged; Penicillanic Acid; Piperacillin; Tazobactam | 1993 |
Intramuscular meropenem in the treatment of bacterial infections of the urinary and lower respiratory tracts. Italian Intramuscular Meropenem Study Group.
Topics: Bacterial Infections; Carbapenems; Ceftazidime; Cilastatin; Humans; Imipenem; Injections, Intramuscular; Meropenem; Respiratory Tract Infections; Thienamycins; Treatment Outcome; Urinary Tract Infections | 1995 |
Treatment of acute bacterial exacerbations of chronic obstructive pulmonary disease in hospitalised patients--a comparison of meropenem and imipenem/cilastatin. COPD Study Group.
Topics: Bacterial Infections; Bronchitis; Carbapenems; Cilastatin; Drug Therapy, Combination; Drug Tolerance; Hospitalization; Humans; Imipenem; Lung Diseases, Obstructive; Meropenem; Prospective Studies; Thienamycins; Treatment Outcome | 1995 |
Meropenem versus imipenem/cilastatin in intra-abdominal infections requiring surgery. Meropenem Study Group.
Topics: Abdomen; Adolescent; Adult; Aged; Bacterial Infections; Carbapenems; Cilastatin; Drug Therapy, Combination; Humans; Imipenem; Injections, Intravenous; Meropenem; Middle Aged; Thienamycins; Treatment Outcome | 1995 |
Intravenous meropenem versus imipenem/cilastatin in the treatment of serious bacterial infections in hospitalized patients. Meropenem Serious Infection Study Group.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Hospitals; Humans; Imipenem; Infusions, Intravenous; Injections, Intravenous; Male; Meropenem; Middle Aged; Peritonitis; Protease Inhibitors; Respiratory Tract Infections; Thienamycins; Time Factors; Treatment Outcome; Urinary Tract Infections | 1996 |
Management of intra-abdominal infections. The case for intraoperative cultures and comprehensive broad-spectrum antibiotic coverage. The Canadian Intra-abdominal Infection Study Group.
Topics: Abdomen; Antibiotic Prophylaxis; Bacteria; Bacterial Infections; Cause of Death; Cefoxitin; Cephamycins; Cilastatin; Double-Blind Method; Drainage; Drug Resistance, Microbial; Female; Humans; Imipenem; Injections, Intravenous; Intraoperative Care; Male; Middle Aged; Peritonitis; Prospective Studies; Protease Inhibitors; Thienamycins; Treatment Failure; Treatment Outcome | 1996 |
Biapenem versus imipenem/cilastatin in the treatment of complicated intra-abdominal infections: report from a Swedish Study Group.
Topics: Abdomen; Abdominal Abscess; Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Humans; Imipenem; Infusions, Intravenous; Male; Middle Aged; Protease Inhibitors; Safety; Sweden; Thienamycins; Treatment Outcome | 1996 |
A comparison of imipenem/cilastatin with the combination of cefuroxime and metronidazole in the treatment of intra-abdominal infections.
Topics: Abdomen; Abdominal Abscess; Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cefuroxime; Cilastatin; Drug Therapy, Combination; Humans; Imipenem; Metronidazole; Microbial Sensitivity Tests; Middle Aged; Treatment Outcome | 1996 |
Cost-effectiveness of ampicillin/sulbactam versus imipenem/cilastatin in the treatment of limb-threatening foot infections in diabetic patients.
Topics: Adult; Aged; Ampicillin; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cost-Benefit Analysis; Diabetes Mellitus, Type 1; Drug Costs; Drug Therapy; Drug Therapy, Combination; Foot Diseases; Hospital Costs; Hospitalization; Humans; Imipenem; Microbial Sensitivity Tests; Middle Aged; Penicillins; Protease Inhibitors; Sulbactam; Thienamycins | 1997 |
[Comparison between monotherapy with imipenem/cilastatin sodium (IPM/CS) and combinations of IPM/CS and other drugs for treating bacterial infections in patients with hematopoietic disorders].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Imipenem; Immunocompromised Host; Male; Middle Aged; Opportunistic Infections; Penicillins | 1996 |
[Meropenem (Merrem) vs imipenem/cilastatin in hospital treatment of intra-abdominal infections. A multicenter study].
Topics: Abdomen; Adolescent; Adult; Aged; Bacterial Infections; Cilastatin; Female; Follow-Up Studies; Humans; Imipenem; Infusions, Intravenous; Male; Meropenem; Middle Aged; Protease Inhibitors; Thienamycins; Time Factors | 1997 |
Randomized trial comparing netilmicin plus imipenem-cilastatin versus netilmicin plus ceftazidime as empiric therapy for febrile neutropenic bone marrow transplant recipients.
Topics: Adolescent; Adult; Bacteria; Bacterial Infections; Bone Marrow Transplantation; Ceftazidime; Cephalosporins; Child; Cilastatin; Drug Synergism; Drug Therapy, Combination; Female; Fever; Gentamicins; Humans; Imipenem; Male; Middle Aged; Netilmicin; Neutropenia; Postoperative Complications; Protease Inhibitors; Thienamycins; Treatment Outcome | 1997 |
Imipenem/cilastatin (1.5 g daily) versus meropenem (3.0 g daily) in patients with intra-abdominal infections: results of a prospective, randomized, multicentre trial.
Topics: Abdomen; Adult; Aged; Anti-Bacterial Agents; APACHE; Bacterial Infections; Cilastatin; Female; Humans; Imipenem; Infusions, Intravenous; Male; Meropenem; Middle Aged; Prospective Studies; Protease Inhibitors; Thienamycins; Treatment Outcome | 1997 |
Impact an anatomical site on bacteriological and clinical outcome in the management of intra-abdominal infections.
Topics: Adult; Aged; Anti-Bacterial Agents; Appendicitis; Bacterial Infections; Bacteriological Techniques; Cause of Death; Cilastatin; Clindamycin; Combined Modality Therapy; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Imipenem; Male; Meropenem; Middle Aged; Peritonitis; Risk Factors; Survival Rate; Thienamycins; Tobramycin; Treatment Outcome | 1998 |
Treatment of obstetric and gynecologic infections with meropenem: comparison with imipenem/cilastatin.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Follow-Up Studies; Genital Diseases, Female; Humans; Imipenem; Infusions, Intravenous; Injections, Intravenous; Meropenem; Middle Aged; Protease Inhibitors; Thienamycins; Treatment Outcome | 1998 |
Trovafloxacin in the treatment of intra-abdominal infections: results of a double-blind, multicenter comparison with imipenem/cilastatin. Trovafloxacin Surgical Group.
Topics: Abdomen; Administration, Oral; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Cilastatin; Clavulanic Acid; Double-Blind Method; Female; Fluoroquinolones; Humans; Imipenem; Injections, Intravenous; Male; Middle Aged; Naphthyridines; Penicillins; Prospective Studies; Protease Inhibitors; Surgical Wound Infection; Thienamycins; Treatment Outcome | 1998 |
Cost-minimization analysis of piperacillin/tazobactam versus imipenem/cilastatin for the treatment of serious infections: a Canadian hospital perspective.
Topics: Adult; Anti-Infective Agents; Bacterial Infections; British Columbia; Cilastatin; Costs and Cost Analysis; Decision Trees; Double-Blind Method; Drug Therapy, Combination; Economics, Pharmaceutical; Enzyme Inhibitors; Female; Humans; Imipenem; Male; Models, Economic; Penicillanic Acid; Penicillins; Piperacillin; Prospective Studies; Protease Inhibitors; Statistics, Nonparametric; Tazobactam; Thienamycins; Treatment Outcome | 1999 |
Cost effectiveness of ciprofloxacin plus metronidazole versus imipenem-cilastatin in the treatment of intra-abdominal infections.
Topics: Abdomen; Aged; Anti-Infective Agents; Bacterial Infections; Cilastatin; Ciprofloxacin; Cost-Benefit Analysis; Double-Blind Method; Drug Combinations; Female; Humans; Imipenem; Male; Metronidazole; Middle Aged; Protease Inhibitors; Thienamycins | 1999 |
Results of a clinical trial of clinafloxacin versus imipenem/cilastatin for intraabdominal infections.
Topics: Abdomen; Adult; Anti-Infective Agents; Bacterial Infections; Cilastatin; Double-Blind Method; Female; Fluoroquinolones; Humans; Imipenem; Logistic Models; Male; Middle Aged; Prospective Studies; Protease Inhibitors; Thienamycins | 2001 |
Meropenem versus imipenem/cilastatin as empirical monotherapy for serious bacterial infections in the intensive care unit.
Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Belgium; Cilastatin; Drug Combinations; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Imipenem; Infusions, Intravenous; Intensive Care Units; Male; Meropenem; Middle Aged; Protease Inhibitors; Thienamycins; Treatment Outcome | 2000 |
[Combination therapy of antibiotics and intravenous immunoglobulin].
Topics: Amikacin; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Humans; Imipenem; Immunoglobulins, Intravenous; Multicenter Studies as Topic; Protease Inhibitors; Randomized Controlled Trials as Topic; Thienamycins | 2001 |
Imipenem/cilastatin as empirical treatment of severe infections in compromised patients.
Topics: Adult; Bacterial Infections; Cilastatin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Imipenem; Immunocompromised Host; Infusions, Intravenous; Male; Middle Aged; Protease Inhibitors; Severity of Illness Index; Thienamycins; Treatment Outcome | 1991 |
Piperacillin-tazobactam versus imipenem-cilastatin for treatment of intra-abdominal infections.
Topics: Abdomen; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibitors; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Piperacillin; Tazobactam; Treatment Outcome | 1992 |
Randomized multicenter clinical trial with imipenem/cilastatin versus cefotaxime/gentamicin in the treatment of patients with non-life-threatening infections. German and Austrian Imipenem/Cilastatin Study Group.
Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Cefotaxime; Cilastatin; Drug Therapy, Combination; Female; Gentamicins; Humans; Imipenem; Male; Middle Aged | 1992 |
[Clinical studies on imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Genital Diseases, Female; Humans; Imipenem; Infusions, Intravenous; Middle Aged; Postoperative Complications | 1992 |
[Evaluation of three types of empirical antibiotherapy in patients with febrile neutropenia: imipenem-cilastatin versus ceftazidime-vancomycin versus ticarcillin-amikacin-vancomycin].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Bacterial Infections; Ceftazidime; Cilastatin; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Middle Aged; Neutropenia; Prospective Studies; Ticarcillin; Vancomycin | 1992 |
Imipenem-cilastatin vs. tobramycin and metronidazole for appendicitis-related infections.
Topics: Adolescent; Anti-Bacterial Agents; Appendicitis; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Infant; Male; Metronidazole; Tobramycin | 1992 |
Trimethoprim-sulfamethoxazole plus amikacin as first-line therapy and imipenem/cilastatin as second empirical therapy in febrile neutropenic patients with hematological disorders.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Bacterial Infections; Bone Marrow Transplantation; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Fever; Hematologic Diseases; Humans; Imipenem; Leukemia; Lymphoma; Male; Middle Aged; Neutropenia; Pneumocystis Infections; Sepsis; Trimethoprim, Sulfamethoxazole Drug Combination | 1992 |
A randomized trial comparing imipenem/cilastatine alone with latamoxef plus tobramycin in febrile neutropenic patients with lung cancer.
Topics: Adult; Aged; Bacterial Infections; Chi-Square Distribution; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Fever; Humans; Imipenem; Logistic Models; Lung Neoplasms; Male; Middle Aged; Moxalactam; Multivariate Analysis; Neutropenia; Random Allocation; Tobramycin; Treatment Outcome | 1991 |
Single dose imipenem-cilastatin compared with three doses of cefuroxime and metronidazole as prophylaxis in elective colorectal surgery: a prospective randomized study.
Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Cefuroxime; Cilastatin; Colorectal Neoplasms; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Metronidazole; Middle Aged; Postoperative Complications; Premedication; Prospective Studies | 1991 |
Twice daily intramuscular imipenem/cilastatin in the treatment of skin and soft tissue infections.
Topics: Abscess; Bacterial Infections; Cellulitis; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Humans; Imipenem; Injections, Intramuscular; Skin Diseases, Infectious; Wound Infection | 1991 |
Intramuscular imipenem/cilastatin in multiple-dose treatment regimens: review of the worldwide clinical experience.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Injections, Intramuscular; Male; Middle Aged; Pelvic Inflammatory Disease; Respiratory Tract Infections; Skin Diseases, Infectious; United States; Urinary Tract Infections | 1991 |
[Laboratory and clinical studies on imipenem/cilastatin sodium plus amikacin sulfate in patients with severe infections complicating hematological disorders].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Imipenem; In Vitro Techniques; Infusions, Intravenous; Injections, Intramuscular; Male; Middle Aged | 1991 |
[Clinical evaluation of imipenem/cilastatin sodium in the internal medicine].
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Male; Middle Aged | 1991 |
[Clinical evaluation of imipenem/cilastatin sodium as a second line regimen in severe infections associated with hematologic disorders].
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Evaluation; Female; Hematologic Diseases; Humans; Imipenem; Infusions, Intravenous; Male; Middle Aged | 1991 |
[Clinical evaluation of imipenem/cilastatin sodium against severe infections complicating hematological disorders and solid tumors].
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Evaluation; Female; Humans; Imipenem; Leukemia; Lymphoma; Male; Middle Aged; Myeloproliferative Disorders; Neoplasms | 1991 |
Imipenem/cilastatin (Primaxin): evaluation in general surgical practice.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Evaluation; Female; Humans; Imipenem; Male; Middle Aged | 1991 |
Imipenem/cilastatin treatment of bacterial meningitis in children.
Topics: Anti-Bacterial Agents; Bacterial Infections; Child, Preschool; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Infant; Male; Meningitis; Meningitis, Haemophilus; Meningitis, Meningococcal; Retrospective Studies; Seizures | 1991 |
Clinical evaluation of the imipenem/cilastatin combination in the therapy of severe infections in patients with malignant diseases.
Topics: Adult; Aged; Bacteria; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Middle Aged; Neoplasms | 1990 |
[Value of an imipenem-cilastatin combination in surgery and surgical care units].
Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Humans; Imipenem; Intensive Care Units; Male; Middle Aged; Multicenter Studies as Topic; Postoperative Care | 1990 |
[An imipenem-cilastatin combination in the treatment of infection at general intensive care units].
Topics: Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Humans; Imipenem; Intensive Care Units; Male; Middle Aged; Multicenter Studies as Topic | 1990 |
[An imipenem-cilastatin combination in the treatment of infection in hemato-oncology].
Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Drug Combinations; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Imipenem; Male; Middle Aged; Multicenter Studies as Topic; Neoplasms | 1990 |
[Imipenem-cilastatin in infections].
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Middle Aged; Multicenter Studies as Topic | 1990 |
The efficacy and safety of imipenem/cilastatin in the treatment of severe bacterial infections.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cilastatin; Drug Synergism; Drug Therapy, Combination; Endocarditis, Bacterial; Female; Humans; Imipenem; Male; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Urinary Tract Infections | 1990 |
Antimicrobial management of postoperative infections in abdominal surgery: single or combination regimen?
Topics: Abdomen; Amoxicillin; Anti-Infective Agents; Bacterial Infections; Cilastatin; Clindamycin; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Middle Aged; Postoperative Complications; Prospective Studies; Randomized Controlled Trials as Topic; Surgical Wound Infection | 1990 |
Ceftazidime versus imipenem-cilastatin as initial monotherapy for febrile neutropenic patients.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Anti-Bacterial Agents; Antineoplastic Agents; Bacteria; Bacterial Infections; Ceftazidime; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Fever; Humans; Imipenem; Male; Microbial Sensitivity Tests; Middle Aged; Neutropenia; Prospective Studies; Randomized Controlled Trials as Topic | 1990 |
[Clinical evaluation of imipenem/cilastatin sodium in infectious complications of hematological malignancies. Tohkai Research Group on Infections in Hematological Disorders].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cilastatin; Drug Combinations; Female; Hematologic Diseases; Humans; Imipenem; Injections, Intravenous; Male; Middle Aged | 1990 |
Ceftriaxone versus imipenem/cilastatin as empirical monotherapy for infections in cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Ceftriaxone; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Middle Aged; Neutropenia; Prospective Studies; Random Allocation; Remission Induction | 1989 |
[Pharmacokinetic and clinical evaluations of imipenem/cilastatin sodium in neonates and premature infants].
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Drug Combinations; Female; Humans; Imipenem; Infant, Newborn; Infant, Premature, Diseases; Male; Multicenter Studies as Topic | 1989 |
[Therapeutic effects of imipenem/cilastatin sodium against severe infections in patients with hematopoietic disorders. Hanshin Infection Study Group].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Drug Combinations; Female; Humans; Imipenem; Infusions, Intravenous; Leukemia, Myeloid, Acute; Leukocyte Count; Lymphoma; Male; Middle Aged | 1989 |
[Pharmacokinetic and clinical evaluation of imipenem/cilastatin sodium in neonates and premature infants. A study of imipenem/cilastatin sodium by a perinatal co-research group].
Topics: Age Factors; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Half-Life; Humans; Imipenem; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Male; Multicenter Studies as Topic | 1989 |
Imipenem-cilastatin in pediatric patients: an overview of safety and efficacy in studies conducted in the United States.
Topics: Adolescent; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Imipenem; Infant; Infant, Newborn; Male; Multicenter Studies as Topic; Prospective Studies; United States | 1989 |
Imipenem/cilastatin versus piperacillin plus amikacin as empiric therapy in the treatment of febrile episodes in neutropenic patients with haematologic malignancies.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Female; Humans; Imipenem; Leukemia; Lymphoma; Male; Middle Aged; Neutropenia; Piperacillin; Prospective Studies; Random Allocation | 1989 |
Imipenem/cilastatin as monotherapy in severe infections: comparison with cefotaxime in combination with metronidazole and cloxacillin. Report from a Norwegian Study Group.
Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Cefotaxime; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Cloxacillin; Cyclopropanes; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Metronidazole; Random Allocation; Thienamycins | 1987 |
[Pharmacokinetic and clinical studies on imipenem/cilastatin sodium in the perinatal period. A study of imipenem/cilastatin sodium in the perinatal co-research group].
Topics: Amniotic Fluid; Bacteria; Bacterial Infections; Cilastatin; Drug Evaluation; Drug Therapy, Combination; Female; Fetal Blood; Half-Life; Humans; Imipenem; Labor, Obstetric; Milk, Human; Multicenter Studies as Topic; Pregnancy; Pregnancy Complications, Infectious; Puerperal Infection | 1988 |
[Clinical experience with imipenem/cilastatin in the treatment of severe infections in general surgery].
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Male; Middle Aged; Postoperative Complications; Prospective Studies; Thienamycins | 1986 |
Clinical trial of imipenem/cilastatin in severely burned and infected patients.
Topics: Adult; Aged; Bacterial Infections; Burns; Cilastatin; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Drug Evaluation; Drug Resistance, Microbial; Female; Humans; Imipenem; Male; Pseudomonas aeruginosa; Thienamycins | 1987 |
Randomized trial of imipenem-cilastatin versus gentamicin plus clindamycin in the treatment of polymicrobial infections.
Topics: Adult; Aged; Bacteria; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Clindamycin; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Gentamicins; Humans; Imipenem; Male; Middle Aged; Random Allocation | 1988 |
Prospective study comparing imipenem-cilastatin with clindamycin and gentamicin for the treatment of serious surgical infections.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Clindamycin; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Drug Therapy, Combination; Female; Gentamicins; Humans; Imipenem; Male; Middle Aged; Prospective Studies; Random Allocation; Thienamycins | 1988 |
Factors predisposing to seizures in seriously ill infected patients receiving antibiotics: experience with imipenem/cilastatin.
Topics: Anti-Bacterial Agents; Bacterial Infections; Body Weight; Central Nervous System Diseases; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Kidney Function Tests; Male; Regression Analysis; Retrospective Studies; Risk Factors; Seizures; Thienamycins; Time Factors; United States | 1988 |
Imipenem/cilastatin therapy of infections in cancer patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cilastatin; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Female; Fever; Humans; Imipenem; Leukemia; Male; Middle Aged; Neoplasms; Pneumonia; Sepsis; Thienamycins | 1987 |
Randomized comparison of imipenem/cilastatin and ceftazidime in the empiric therapy of severe abdominal infections. A multicenter study.
Topics: Bacterial Infections; Ceftazidime; Cilastatin; Cyclopropanes; Digestive System Diseases; Dipeptidases; Drug Evaluation; Drug Therapy, Combination; Humans; Imipenem; Metronidazole; Random Allocation; Thienamycins | 1987 |
Prospective randomized controlled study of ciprofloxacin versus imipenem-cilastatin in severe clinical infections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cilastatin; Ciprofloxacin; Clinical Trials as Topic; Cyclopropanes; Female; Humans; Imipenem; Male; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Random Allocation; Thienamycins | 1987 |
Imipenem/cilastatin versus aminoglycoside plus amoxicillin plus clindamycin in the treatment of serious postoperative infections.
Topics: Adult; Aminoglycosides; Amoxicillin; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Clindamycin; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Drug Therapy, Combination; Humans; Imipenem; Postoperative Complications; Prospective Studies; Random Allocation; Thienamycins | 1987 |
Efficacy and safety of imipenem/cilastatin in the empirical treatment of septicemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Male; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Sepsis; Thienamycins | 1987 |
Intramuscular imipenem/cilastatin in the treatment of mild and moderate infections.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Cyclopropanes; Drug Administration Schedule; Drug Combinations; Humans; Imipenem; Injections, Intramuscular; Thienamycins | 1987 |
Imipenem/cilastatin therapy for serious infections in neonates and infants.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Infant; Infant, Low Birth Weight; Infant, Newborn; Male; Thienamycins | 1987 |
Imipenem/cilastatin for pediatric infections in hospitalized patients.
Topics: Adolescent; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Cyclopropanes; Drug Administration Schedule; Drug Combinations; Female; Humans; Imipenem; Infant; Infant, Newborn; Infusions, Intravenous; Male; Thienamycins | 1987 |
Treatment of acute bacterial peritonitis: a trial of imipenem/cilastatin against ampicillin-metronidazole-gentamicin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Drug Therapy, Combination; Female; Gentamicins; Humans; Imipenem; Male; Metronidazole; Middle Aged; Peritonitis; Random Allocation; Thienamycins | 1987 |
Imipenem/cilastatin versus amikacin plus piperacillin in the treatment of infections in neutropenic patients: a prospective, randomized multi-clinic study.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Imipenem; Male; Middle Aged; Neutropenia; Penicillin Resistance; Piperacillin; Prospective Studies; Random Allocation; Thienamycins | 1987 |
Treatment of intra-abdominal infections using imipenem/cilastatin.
Topics: Aged; Ampicillin; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Drug Combinations; Female; Gentamicins; Humans; Imipenem; Male; Metronidazole; Peritonitis | 1987 |
Comparison of cefoperazone and mezlocillin with imipenem as empiric therapy in febrile neutropenic cancer patients.
Topics: Adult; Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Cefoperazone; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Drug Combinations; Drug Therapy, Combination; Female; Fever; Humans; Imipenem; Male; Mezlocillin; Neoplasms; Neutropenia; Thienamycins | 1988 |
Imipenem-cilastatin sodium (Primaxin).
Topics: Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Drug Resistance, Microbial; Humans; Imipenem; Kinetics; Microbial Sensitivity Tests; Thienamycins | 1986 |
[Effect and tolerance of daily 2 X 1 g imipenem/cilastatin in general surgery].
Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Male; Middle Aged; Postoperative Complications; Prospective Studies; Thienamycins | 1986 |
[Fundamental and clinical studies of imipenem/cilastatin sodium in the field of obstetrics and gynecology. Study group of imipenem/cilastatin sodium in the field of obstetric and gynecological infections].
Topics: Adult; Aged; Bacteria; Bacterial Infections; Cilastatin; Clinical Trials as Topic; Cyclopropanes; Dipeptidases; Drug Combinations; Drug Resistance, Microbial; Female; Genital Diseases, Female; Genitalia, Female; Humans; Imipenem; Middle Aged; Thienamycins | 1986 |
Imipenem-cilastatin as initial therapy for febrile cancer patients.
Topics: Adult; Bacterial Infections; Cilastatin; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Female; Fever; Humans; Imipenem; Male; Middle Aged; Neoplasms; Neutropenia; Pneumonia; Sepsis; Thienamycins | 1986 |
Imipenem and cilastatin in acute osteomyelitis and suppurative arthritis. Therapy in infants and children.
Topics: Acute Disease; Administration, Oral; Anti-Bacterial Agents; Arthritis, Infectious; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Cyclopropanes; Drainage; Drug Combinations; Female; Follow-Up Studies; Humans; Imipenem; Infant; Infusions, Intravenous; Male; Osteomyelitis; Random Allocation; Suppuration; Thienamycins | 1987 |
Imipenem/cilastatin therapy of serious infections: a U.S. multicenter noncomparative trial.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Clinical Trials as Topic; Cyclopropanes; Dipeptidases; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Imipenem; Male; Middle Aged; Surgical Wound Infection; Thienamycins; Urinary Tract Infections | 1985 |
Treatment of skin and soft tissue infections with imipenem/cilastatin.
Topics: Adult; Aged; Bacteria; Bacterial Infections; Cellulitis; Cilastatin; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Humans; Imipenem; Middle Aged; Skin Diseases, Infectious; Thienamycins | 1985 |
Role of imipenem/cilastatin in the treatment of soft tissue infections.
Topics: Abscess; Adolescent; Adult; Aged; Bacterial Infections; Carbuncle; Cellulitis; Cilastatin; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Drug Resistance, Microbial; Female; Furunculosis; Humans; Imipenem; Male; Middle Aged; Skin Ulcer; Thienamycins; Wound Infection | 1985 |
Randomized trial of imipenem/cilastatin versus gentamicin and clindamycin in mixed flora infections.
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Clindamycin; Clinical Trials as Topic; Creatinine; Cyclopropanes; Drug Combinations; Female; Gentamicins; Humans; Imipenem; Male; Middle Aged; Random Allocation; Seizures; Thienamycins | 1985 |
Imipenem/cilastatin: the first carbapenem antibiotic.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Chemical Phenomena; Chemistry; Cilastatin; Clinical Trials as Topic; Cyclopropanes; Dipeptidases; Humans; Imipenem; Kinetics; Thienamycins | 1985 |
143 other study(ies) available for cilastatin and Bacterial Disease
| Article | Year |
|---|---|
Commentary on: A Retrospective Comparison of the Efficacy of Embolization with Imipenem/Cilastatin and Microspheres in the Management of Chronic Shoulder Pain.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Humans; Microspheres; Retrospective Studies; Shoulder Pain | 2023 |
Effectiveness and Safety of Intra-arterial Imipenem/Cilastatin Sodium Infusion for Patients with Hand Osteoarthritis-Related Interphalangeal Joint Pain.
Topics: Arthralgia; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Humans; Imipenem; Infusions, Intra-Arterial; Osteoarthritis; Retrospective Studies | 2023 |
Embolic Characteristics of Imipenem-Cilastatin Particles in Vitro and in Vivo: Implications for Transarterial Embolization in Joint Arthropathies.
Topics: Animals; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Therapy, Combination; Imipenem; Joint Diseases; Male; Rats; Rats, Sprague-Dawley | 2021 |
Imipenem/cilastatin encapsulated polymeric nanoparticles for destroying carbapenem-resistant bacterial isolates.
Topics: Anti-Bacterial Agents; Bacterial Adhesion; Bacterial Infections; beta-Lactam Resistance; Biofilms; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Carriers; Drug Combinations; Drug Resistance, Multiple, Bacterial; Imipenem; Klebsiella pneumoniae; Lactic Acid; Microbial Sensitivity Tests; Nanoparticles; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pseudomonas aeruginosa | 2017 |
Nontherapeutic equivalence of a generic product of imipenem-cilastatin is caused more by chemical instability of the active pharmaceutical ingredient (imipenem) than by its substandard amount of cilastatin.
Topics: Animals; Bacteria; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Disease Models, Animal; Drug Stability; Drugs, Generic; Humans; Imipenem; Klebsiella pneumoniae; Mice; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus; Therapeutic Equivalency | 2019 |
Impact of the introduction of real-time therapeutic drug monitoring on empirical doses of carbapenems in critically ill burn patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Body Surface Area; Burn Units; Burns; Carbapenems; Cilastatin; Cilastatin, Imipenem Drug Combination; Cohort Studies; Computer Systems; Critical Illness; Drug Combinations; Drug Monitoring; Female; Humans; Imipenem; Length of Stay; Male; Meropenem; Middle Aged; Retrospective Studies; Thienamycins; Young Adult | 2015 |
Therapeutic equivalence of generic imipenem/cilastatin for therapy of infections at Siriraj Hospital.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cross Infection; Drugs, Generic; Female; Hospitalization; Hospitals, University; Humans; Imipenem; Male; Medical Records; Middle Aged; Thailand; Therapeutic Equivalency; Treatment Outcome | 2010 |
Empiric, broad-spectrum antibiotic therapy with an aggressive de-escalation strategy does not induce gram-negative pathogen resistance in ventilator-associated pneumonia.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Ventilator-Associated; Retrospective Studies; Tobramycin | 2010 |
Carbapenems.
Topics: Anti-Bacterial Agents; Bacterial Infections; Carbapenems; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Drug Administration Schedule; Drug Combinations; Humans; Imipenem; Infant; Infant, Newborn; Infant, Premature | 2002 |
[Antibacterial activity of biapenem against recent clinical isolates].
Topics: Bacteria; Bacterial Infections; beta-Alanine; Carbapenems; Ceftazidime; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Resistance, Bacterial; Humans; Imipenem; Meropenem; Thienamycins | 2003 |
[Proper use of carbapenem antibiotics based on the feature in the treatment of infectious diseases (discussion)]].
Topics: Bacteria; Bacterial Infections; beta-Alanine; Carbapenems; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Administration Schedule; Drug Combinations; Drug Resistance, Bacterial; Humans; Imipenem; Meropenem; Thienamycins; Treatment Failure | 2004 |
Pharmacodynamic evaluation of extending the administration time of meropenem using a Monte Carlo simulation.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Models, Biological; Monte Carlo Method; Pseudomonas aeruginosa; Thienamycins; Time Factors | 2005 |
The cost-effectiveness of cefepime plus metronidazole versus imipenem/cilastatin in the treatment of complicated intra-abdominal infection.
Topics: Adult; Aged; APACHE; Bacterial Infections; Cefepime; Cephalosporins; Cilastatin; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Follow-Up Studies; Gastrointestinal Diseases; Humans; Imipenem; Male; Metronidazole; Middle Aged; Probability; Retrospective Studies; Treatment Outcome | 2004 |
A clinical study of imipenem/cilastatin in the treatment of generalized and localized infections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Male; Middle Aged; Survival Analysis; Treatment Outcome; Urinary Tract Infections | 1989 |
Clinical evaluation of imipenemcilastatin in the therapy of severe infections in high risk patients.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Male; Safety | 1989 |
Imipenem/cilastatin as monotherapy in the treatment of acute or chronic lung infections: clinical efficacy and safety.
Topics: Acute Disease; Adult; Aged; Bacterial Infections; Chronic Disease; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Lung Diseases; Male; Microbial Sensitivity Tests; Middle Aged; Pneumonia; Pulmonary Disease, Chronic Obstructive; Safety | 1989 |
Puerperal infections: experiences with imipenem/cilastatin.
Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Leukocyte Count; Puerperal Disorders | 1989 |
Imipenem/cilastatin as initial single-agent therapy for infections in cancer patients with neutropenia.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteremia; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Humans; Imipenem; Microbial Sensitivity Tests; Middle Aged; Neoplasms; Neutropenia; Treatment Outcome | 1989 |
Cost-utility analysis comparing meropenem with imipenem plus cilastatin in the treatment of severe infections in intensive care.
Topics: Aged; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cohort Studies; Cost-Benefit Analysis; Decision Support Techniques; Dipeptidases; Drug Combinations; Female; Humans; Intensive Care Units; Male; Markov Chains; Meropenem; Middle Aged; Quality-Adjusted Life Years; Sensitivity and Specificity; Thienamycins | 2006 |
Pharmacodynamic modeling of imipenem-cilastatin, meropenem, and piperacillin-tazobactam for empiric therapy of skin and soft tissue infections: a report from the OPTAMA Program.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Dose-Response Relationship, Drug; Drug Combinations; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Models, Biological; Monte Carlo Method; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Population Surveillance; Prevalence; Soft Tissue Infections; Thienamycins | 2005 |
Prospective determination of plasma imipenem concentrations in critically ill children.
Topics: Anti-Bacterial Agents; Area Under Curve; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cilastatin, Imipenem Drug Combination; Critical Illness; Cross Infection; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Infant; Infant, Newborn; Infusions, Intravenous; Male | 2006 |
CW-270033, a novel pyrrolidinyl-thio carbapenem, has potent antimicrobial activity in vitro and in vivo.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Carbapenems; Cilastatin; Dose-Response Relationship, Drug; Enterococcus faecalis; Escherichia coli; Injections, Intravenous; Meropenem; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Molecular Structure; Protease Inhibitors; Pseudomonas aeruginosa; Pyrrolidines; Staphylococcus aureus; Thienamycins; Vancomycin Resistance | 2007 |
Pharmacokinetic-pharmacodynamic modeling and simulation for in vivo bactericidal effect in murine infection model.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Bacterial Infections; Carbapenems; Cilastatin; Disease Models, Animal; Doripenem; Female; Imipenem; Meropenem; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Models, Biological; Thienamycins | 2008 |
Imipenem/cilastatin.
Topics: Absorption; Adult; Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Child; Cilastatin; Cyclopropanes; Drug Combinations; Drug Resistance, Microbial; Humans; Imipenem; Kidney Tubules; Kinetics; Thienamycins | 1984 |
[New approaches in the use of antibiotics in the treatment of postoperative intra-abdominal infections].
Topics: Abdomen; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Carbapenems; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Male; Middle Aged; Postoperative Complications | 1995 |
[Thienam (imipenem/cilastatin) as an agent for empirical antibiotic therapy].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Evaluation; Female; Humans; Imipenem; Infant; Infant, Newborn; Male; Microbial Sensitivity Tests; Middle Aged | 1993 |
The antimicrobial activity of imipenem/cilastatin and its treatment in critical ill patients with polymicrobial and mixed infection.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Male; Microbial Sensitivity Tests; Middle Aged | 1993 |
[Clinical evaluation of imipenem/cilastatin sodium and fosfomycin as second-line combination chemotherapy in severe infections associated with hematologic disorders].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cilastatin; Drug Evaluation; Drug Therapy, Combination; Female; Fosfomycin; Hematologic Diseases; Humans; Imipenem; Male; Middle Aged | 1993 |
[Chemotherapy with imipenem/cilastatin for severe infections accompanied by malignant hematological disorders].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Hematologic Diseases; Humans; Imipenem; Immunocompromised Host; Leukocyte Count; Male; Middle Aged; Neutrophils | 1993 |
Ticarcillin-clavulanate as an alternative to imipenem-cilastatin.
Topics: Bacterial Infections; Cilastatin; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Humans; Imipenem; Protease Inhibitors; Ticarcillin | 1995 |
[Extremity gangrene caused by rare co-infection of multiple bacteria: a case report].
Topics: Adolescent; Amputation, Surgical; Anti-Bacterial Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; Cilastatin; Debridement; Female; Forearm; Gangrene; Humans; Protease Inhibitors | 1996 |
[Meropenem in the treatment of surgical intra-abdominal infections].
Topics: Abdomen; Bacterial Infections; Cilastatin; Drug Combinations; Humans; Imipenem; Meropenem; Postoperative Complications; Thienamycins | 1997 |
Neurotoxicity due to imipenem/cilastatin in patients on continuous ambulatory peritoneal dialysis.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Humans; Imipenem; Kidney Failure, Chronic; Male; Middle Aged; Myoclonus; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis; Protease Inhibitors; Pruritus; Thienamycins | 1999 |
Cost efficacy of tazobactam/piperacillin versus imipenem/cilastatin in the treatment of intra-abdominal infection.
Topics: Abdomen; Adult; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Cost-Benefit Analysis; Decision Trees; Drug Combinations; Drug Costs; Drug Therapy, Combination; Health Care Costs; Humans; Imipenem; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Protease Inhibitors; Randomized Controlled Trials as Topic; Retrospective Studies; Thienamycins | 2001 |
[Clinical evaluation of imipenem/cilastatin sodium against infections in compromised children (malignancy, hematological disease, collagen disease)].
Topics: Adolescent; Age Factors; Bacterial Infections; Child; Child, Preschool; Cilastatin; Collagen Diseases; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Imipenem; Immunocompromised Host; Infant; Male; Neoplasms; Neutropenia; Opportunistic Infections | 1992 |
Imipenem/cilastatin-associated hiccups.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Gentamicins; Hiccup; Humans; Imipenem; Infusions, Intravenous; Male; Middle Aged; Tibial Fractures; Wound Infection | 1992 |
[Therapeutic evaluation of imipenem/cilastatin sodium for bacterial infections in patients with hematological diseases].
Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Cilastatin; Drug Evaluation; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Imipenem; Immunocompromised Host; Leukemia, Myeloid, Acute; Male; Middle Aged | 1992 |
[Clinical study of intramuscular imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Injections, Intramuscular; Microbial Sensitivity Tests; Middle Aged; Uterine Diseases | 1991 |
[Clinical study of intramuscular imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Injections, Intramuscular; Microbial Sensitivity Tests; Middle Aged; Uterine Diseases | 1991 |
Pharmacokinetics of imipenem/cilastatin during continuous arteriovenous hemofiltration.
Topics: Acute Kidney Injury; Adult; Aged; Bacterial Infections; Cilastatin; Cross Infection; Drug Therapy, Combination; Female; Half-Life; Hemofiltration; Humans; Imipenem; Male; Metabolic Clearance Rate; Middle Aged | 1991 |
[Clinical experience with imipenem-cilastatin in intensive therapy].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Child; Cilastatin; Cilastatin, Imipenem Drug Combination; Critical Care; Drug Combinations; Drug Evaluation; Humans; Imipenem; Middle Aged | 1991 |
In vitro and in vivo activities of LJC10,627, a new carbapenem with stability to dehydropeptidase I.
Topics: Amikacin; Animals; Bacterial Infections; Bacteroides fragilis; Carbapenems; Ceftazidime; Cilastatin; Ciprofloxacin; Dipeptidases; Drug Therapy, Combination; Escherichia coli; Female; Imipenem; Klebsiella pneumoniae; Metronidazole; Mice; Microbial Sensitivity Tests; Piperacillin; Pseudomonas aeruginosa; Staphylococcus; Streptococcus; Thienamycins | 1991 |
Evaluation of an imipenem/cilastatin target drug program.
Topics: Adult; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; Central Nervous System Diseases; Cilastatin; Cilastatin, Imipenem Drug Combination; Cost Savings; Drug Combinations; Drug Costs; Drug Monitoring; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Imipenem; Kidney Diseases; Pharmacy Service, Hospital | 1991 |
Imipenem + cilastatin--a new type of antibiotic.
Topics: Bacterial Infections; Cilastatin; Drug Combinations; Imipenem | 1991 |
Changes in clinically separated strains of glucose non-fermented gram-negative bacilli following the induction of imipenem/cilastatin.
Topics: Bacterial Infections; Cilastatin; Cross Infection; Fermentation; Glucose; Gram-Negative Bacteria; Humans; Imipenem; Retrospective Studies | 1991 |
[Clinical evaluation of imipenem/cilastatin sodium against severe infections in patients with hematopoietic disorders].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Administration Schedule; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Imipenem; Infusions, Intravenous; Male; Middle Aged | 1990 |
[Study of imipenem-cilastatin at intensive care units].
Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Humans; Imipenem; Intensive Care Units; Male; Middle Aged | 1990 |
[Clinical study of imipenem/cilastatin sodium in children with severe infections].
Topics: Bacterial Infections; Child; Child, Preschool; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Administration Schedule; Drug Combinations; Female; Hematologic Diseases; Humans; Imipenem; Infant; Male; Neoplasms; Neutropenia | 1990 |
[Imipenem/cilastatin: in vitro activity, concentrations in plasma and prostatic adenoma and therapeutic results in patients with complicated urinary tract infections].
Topics: Adult; Aged; Aged, 80 and over; Bacteria; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Drug Combinations; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Half-Life; Humans; Imipenem; Male; Middle Aged; Premedication; Prostatic Hyperplasia; Thienamycins; Tissue Distribution; Urinary Tract Infections | 1986 |
Single-dose kinetics of imipenem/cilastatin during continuous arteriovenous haemofiltration in intensive care patients.
Topics: Acute Kidney Injury; Adult; Aged; Bacterial Infections; Cilastatin; Critical Care; Drug Therapy, Combination; Female; Hemofiltration; Humans; Imipenem; Male; Middle Aged | 1989 |
[Use of imipenem-cilastatin in antibiotic therapy and prevention in general surgery. One year of clinical experience].
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Evaluation; Female; Humans; Imipenem; Male; Middle Aged; Premedication | 1989 |
[Monotherapy, empirical and targetted, with imipenem-cilastatin in sepsis of bacterial origin].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Evaluation; Female; Fever of Unknown Origin; Humans; Imipenem; Male; Middle Aged | 1989 |
Imipenem-cilastatin sodium.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Humans; Imipenem | 1989 |
[Clinical evaluation of imipenem/cilastatin sodium against severe infections complicated with hematological disorders and solid tumors].
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Evaluation; Female; Hematologic Diseases; Humans; Imipenem; Male; Middle Aged; Neoplasms; Neutrophils | 1989 |
[Clinical and pharmacokinetic study of imipenem/cilastatin in children and newborn infants].
Topics: Adolescent; Bacterial Infections; Child; Child, Preschool; Cilastatin; Drug Therapy, Combination; Enterobacteriaceae Infections; Escherichia coli Infections; Female; Humans; Imipenem; Infant, Newborn; Male; Pseudomonas Infections; Serratia | 1989 |
Clinical evaluation of imipenem/cilastatin in the therapy of severe infections in high-risk patients.
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Female; Humans; Imipenem; Male; Middle Aged; Risk Factors | 1989 |
[Pharmacokinetic, bacteriological and clinical studies on imipenem/cilastatin sodium in neonates].
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Imipenem; Infant, Newborn; Male | 1989 |
[Pharmacokinetic, bacteriological and clinical studies on imipenem/cilastatin sodium in neonates].
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Imipenem; Infant, Newborn; Infusions, Intravenous; Male | 1989 |
[Fundamental and clinical evaluation of imipenem/cilastatin sodium in the field of pediatrics].
Topics: Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Drug Eruptions; Female; Humans; Imipenem; Infant; Infusions, Intravenous; Male; Seizures; Thienamycins | 1986 |
[Bacteriological and clinical evaluations of imipenem/cilastatin sodium in neonates and premature infants].
Topics: Bacteria; Bacterial Infections; Blood Coagulation; Blood Coagulation Tests; Cilastatin; Drug Evaluation; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Imipenem; Infant, Newborn; Infant, Premature, Diseases; Male; Streptococcus agalactiae | 1988 |
[Studies on imipenem/cilastatin sodium in the perinatal period].
Topics: Adult; Amniotic Fluid; Bacterial Infections; Cilastatin; Drug Evaluation; Drug Resistance, Microbial; Drug Therapy, Combination; Escherichia coli; Female; Fetal Blood; Humans; Imipenem; Infusions, Intravenous; Labor, Obstetric; Placenta; Pregnancy; Pregnancy Complications, Infectious; Puerperal Infection; Staphylococcus aureus | 1988 |
[Treatment of bronchopulmonary infections in patients during artificial respiration with imipenem/cilastatin].
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Middle Aged; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections; Respiration, Artificial; Thienamycins | 1986 |
[Imipenem/cilastatin as monotherapy in neutropenic patients with fever].
Topics: Adult; Aged; Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Fever of Unknown Origin; Humans; Imipenem; Male; Middle Aged; Neutropenia; Prospective Studies | 1988 |
[Pharmacokinetic and clinical studies with imipenem/cilastatin sodium in neonates].
Topics: Bacterial Infections; Cilastatin; Drug Evaluation; Drug Therapy, Combination; Female; Half-Life; Humans; Imipenem; Infant, Newborn; Infusions, Intravenous; Male; Platelet Count | 1988 |
[Clinical and pharmacokinetic evaluation of imipenem/cilastatin sodium in neonates and young infants].
Topics: Bacterial Infections; Cilastatin; Drug Evaluation; Drug Therapy, Combination; Female; Half-Life; Humans; Imipenem; Infant; Infant, Newborn; Infusions, Intravenous; Male; Meningitis | 1988 |
[Pharmacokinetic and clinical studies on imipenem/cilastatin sodium in neonates and premature infants].
Topics: Age Factors; Bacterial Infections; Cilastatin; Drug Evaluation; Drug Therapy, Combination; Female; Half-Life; Humans; Imipenem; Infant, Newborn; Infant, Premature, Diseases; Infusions, Intravenous; Male | 1988 |
[Pharmacokinetics and clinical efficacy of imipenem/cilastatin sodium in neonates].
Topics: Absorption; Age Factors; Bacterial Infections; Birth Weight; Cilastatin; Drug Evaluation; Drug Therapy, Combination; Female; Half-Life; Humans; Imipenem; Infant, Newborn; Infusions, Intravenous; Male | 1988 |
[Pharmacokinetics and clinical evaluation of imipenem/cilastatin sodium in pediatric surgery].
Topics: Bacterial Infections; Bile; Biliary Atresia; Chemical Phenomena; Chemistry; Cholangitis; Cilastatin; Drug Evaluation; Drug Therapy, Combination; Female; Half-Life; Hepatitis; Humans; Imipenem; Infant; Infant, Newborn; Male; Postoperative Complications; Premedication | 1988 |
[Evaluation of imipenem/cilastatin sodium in neonatal infections].
Topics: Age Factors; Bacterial Infections; Cilastatin; Drug Evaluation; Drug Therapy, Combination; Female; Half-Life; Humans; Imipenem; Infant; Infant, Newborn; Infusions, Intravenous; Male | 1988 |
[Clinical studies on imipenem/cilastatin sodium in perinatal use].
Topics: Adult; Bacterial Infections; Cilastatin; Drug Evaluation; Drug Therapy, Combination; Endometritis; Female; Humans; Imipenem; Infusions, Intravenous; Pregnancy; Pregnancy Complications, Infectious; Puerperal Infection | 1988 |
[Clinical studies on imipenem/cilastatin sodium in the perinatal period].
Topics: Adult; Bacterial Infections; Cilastatin; Drug Evaluation; Drug Therapy, Combination; Endometritis; Female; Humans; Imipenem; Infusions, Intravenous; Pregnancy; Pregnancy Complications, Infectious; Puerperal Infection; Pyelonephritis | 1988 |
[Study of imipenem/cilastatin sodium in the perinatal period].
Topics: Adult; Amniotic Fluid; Bacterial Infections; Cilastatin; Drug Evaluation; Drug Therapy, Combination; Endometritis; Extraembryonic Membranes; Female; Fetal Blood; Half-Life; Humans; Imipenem; Labor, Obstetric; Placenta; Pregnancy; Pregnancy Complications, Infectious; Puerperal Infection | 1988 |
[Clinical studies on imipenem/cilastatin sodium in the field of obstetrics and gynecology in the perinatal period].
Topics: Adult; Bacterial Infections; Chemical Phenomena; Chemistry; Cilastatin; Drug Evaluation; Drug Therapy, Combination; Endometritis; Female; Humans; Imipenem; Infusions, Intravenous; Mastitis; Pregnancy; Pregnancy Complications, Infectious; Puerperal Infection | 1988 |
[Clinical study of imipenem/cilastatin sodium in the perinatal period].
Topics: Adult; Bacterial Infections; Cilastatin; Drug Evaluation; Drug Therapy, Combination; Endometritis; Female; Humans; Imipenem; Pregnancy; Puerperal Infection | 1988 |
[Fundamental and clinical evaluation of imipenem/cilastatin sodium in the perinatal period].
Topics: Adult; Bacterial Infections; Chemical Phenomena; Chemistry; Cilastatin; Drug Evaluation; Drug Therapy, Combination; Endometritis; Female; Humans; Imipenem; Infusions, Intravenous; Lactation; Milk, Human; Pregnancy; Pregnancy Complications, Infectious; Puerperal Infection; Urinary Tract Infections | 1988 |
[Pharmacokinetic and clinical studies of imipenem/cilastatin sodium in the perinatal period].
Topics: Adult; Amniotic Fluid; Bacterial Infections; Chemical Phenomena; Chemistry; Cilastatin; Drug Evaluation; Drug Therapy, Combination; Female; Fetal Blood; Humans; Imipenem; Infusions, Intravenous; Labor, Obstetric; Pregnancy; Puerperal Infection | 1988 |
Evaluation of imipenem/cilastatin for treatment of infection in an elderly population.
Topics: Aged; Aged, 80 and over; Bacteria; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Imipenem; Male; Thienamycins | 1988 |
Imipenem pharmacokinetics and body fluid concentrations in patients receiving high-dose treatment for serious infections.
Topics: Adult; Aged; Bacterial Infections; Bone and Bones; Cilastatin; Cyclopropanes; Exudates and Transudates; Female; Gastric Juice; Humans; Imipenem; Intestinal Secretions; Male; Middle Aged; Sputum; Suppuration; Thienamycins | 1986 |
Combination imipenem-aminoglycoside therapy.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cyclopropanes; Drug Therapy, Combination; Humans; Imipenem; Thienamycins | 1986 |
Effect of imipenem-cilastatin therapy on fecal flora.
Topics: Adolescent; Bacterial Infections; Candida; Child; Child, Preschool; Cilastatin; Cyclopropanes; Enterobacteriaceae; Feces; Humans; Imipenem; Microbial Sensitivity Tests; Thienamycins | 1986 |
[Clinical studies on the effect of imipenem/cilastatin sodium on infections in obstetrics and gynecology. Tissue concentrations and clinical effects].
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Drug Combinations; Female; Genital Diseases, Female; Genitalia, Female; Humans; Imipenem; Infusions, Intravenous; Kinetics; Maternal-Fetal Exchange; Middle Aged; Pregnancy; Thienamycins | 1986 |
[Fundamental and clinical studies on imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adnexa Uteri; Adult; Bacterial Infections; Cilastatin; Cyclopropanes; Drug Combinations; Fallopian Tubes; Female; Genital Diseases, Female; Humans; Imipenem; Middle Aged; Ovary; Thienamycins; Uterus | 1986 |
[Fundamental and clinical studies on imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Drug Combinations; Female; Genital Diseases, Female; Genitalia, Female; Humans; Imipenem; Kinetics; Middle Aged; Postoperative Complications; Pregnancy; Pregnancy Complications, Infectious; Thienamycins | 1986 |
[Fundamental and clinical studies of imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Drug Combinations; Female; Genital Diseases, Female; Genitalia, Female; Humans; Imipenem; Infusions, Intravenous; Middle Aged; Pregnancy; Puerperal Infection; Thienamycins | 1986 |
[Fundamental and clinical studies of imipenem and imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adult; Bacterial Infections; Cilastatin; Cyclopropanes; Drug Combinations; Female; Genital Diseases, Female; Genitalia, Female; Humans; Hysterectomy; Imipenem; Middle Aged; Postoperative Complications; Pregnancy; Puerperal Infection; Thienamycins | 1986 |
[Imipenem/cilastatin sodium in the treatment of obstetric and gynecologic infections].
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Drug Combinations; Female; Genital Diseases, Female; Humans; Imipenem; Middle Aged; Thienamycins | 1986 |
[Clinical evaluation of imipenem/cilastatin sodium in gynecological infection].
Topics: Adult; Bacteria; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Drug Combinations; Drug Evaluation; Drug Resistance, Microbial; Female; Genital Diseases, Female; Humans; Imipenem; Middle Aged; Thienamycins | 1986 |
[Clinical studies on imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Drug Combinations; Drug Evaluation; Female; Genital Diseases, Female; Genitalia, Female; Humans; Imipenem; Middle Aged; Pregnancy; Thienamycins | 1986 |
[Fundamental and clinical studies of imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adult; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Drug Combinations; Drug Evaluation; Female; Genital Diseases, Female; Humans; Imipenem; Infusions, Intravenous; Middle Aged; Thienamycins | 1986 |
[Pharmacokinetic and clinical studies of imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adult; Bacteria; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Drug Combinations; Drug Resistance, Microbial; Female; Genital Diseases, Female; Genitalia, Female; Humans; Imipenem; Kinetics; Thienamycins | 1986 |
[Fundamental and clinical studies of imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adult; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Drug Combinations; Drug Evaluation; Female; Genital Diseases, Female; Genitalia, Female; Humans; Imipenem; Infusions, Intravenous; Middle Aged; Thienamycins | 1986 |
[Fundamental and clinical studies on imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adult; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Drug Combinations; Drug Evaluation; Female; Genital Diseases, Female; Genitalia, Female; Humans; Imipenem; Infusions, Intravenous; Middle Aged; Thienamycins | 1986 |
[Fundamental and clinical studies on imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Drug Combinations; Drug Evaluation; Female; Genital Diseases, Female; Genitalia, Female; Humans; Imipenem; Infusions, Intravenous; Middle Aged; Thienamycins | 1986 |
[Clinical trials of imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Drug Combinations; Drug Evaluation; Female; Genital Diseases, Female; Humans; Imipenem; Middle Aged; Thienamycins | 1986 |
[Fundamental and clinical studies of imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Drug Combinations; Female; Genital Diseases, Female; Genitalia, Female; Humans; Imipenem; Infusions, Parenteral; Middle Aged; Thienamycins | 1986 |
[Fundamental and clinical studies of imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Drug Combinations; Female; Genital Diseases, Female; Genitalia, Female; Humans; Imipenem; Infusions, Intravenous; Middle Aged; Thienamycins | 1986 |
[Fundamental and clinical studies on imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adult; Aged; Aged, 80 and over; Amniotic Fluid; Bacterial Infections; Child; Cilastatin; Cyclopropanes; Dipeptidases; Drug Combinations; Female; Fetal Blood; Genital Diseases, Female; Genitalia, Female; Humans; Imipenem; Maternal-Fetal Exchange; Middle Aged; Pregnancy; Thienamycins | 1986 |
[Fundamental and clinical studies on imipenem/cilastatin sodium in the field of obstetrics and gynecology].
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Drug Combinations; Drug Evaluation; Female; Genital Diseases, Female; Genitalia, Female; Humans; Imipenem; Middle Aged; Thienamycins | 1986 |
[Clinical and pharmacokinetic evaluation of imipenem/cilastatin sodium in children].
Topics: Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Humans; Imipenem; Infant; Infusions, Intravenous; Kinetics; Pneumonia; Sepsis; Thienamycins; Thyroiditis; Urinary Tract Infections | 1986 |
[Clinical evaluation of imipenem/cilastatin sodium in children].
Topics: Adolescent; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Empyema; Female; Humans; Imipenem; Infant; Infusions, Intravenous; Kinetics; Male; Pneumonia, Staphylococcal; Pyelitis; Sepsis; Thienamycins; Tonsillitis | 1986 |
[Clinical studies on imipenem/cilastatin sodium in pediatric field].
Topics: Adolescent; Agranulocytosis; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Infant; Male; Thienamycins | 1986 |
[Clinical evaluation of imipenem/cilastatin sodium in the pediatric field].
Topics: Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Infant; Kinetics; Lymphadenitis; Male; Respiratory Tract Infections; Thienamycins; Urinary Tract Infections | 1986 |
[Fundamental and clinical studies on imipenem/cilastatin sodium in the pediatric field].
Topics: Adolescent; Bacteria; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Infusions, Intravenous; Kinetics; Male; Thienamycins | 1986 |
[Clinical evaluation of imipenem/cilastatin sodium in children].
Topics: Bacteria; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Infant; Kinetics; Male; Thienamycins | 1986 |
[Fundamental and clinical studies with imipenem/cilastatin sodium, a new carbapenem antibiotic, in the field of pediatrics].
Topics: Adolescent; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Infant; Infusions, Intravenous; Kinetics; Male; Thienamycins | 1986 |
[Fundamental and clinical studies on imipenem/cilastatin sodium in pediatrics].
Topics: Adolescent; Bacteria; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Infant; Infusions, Intravenous; Kinetics; Male; Thienamycins | 1986 |
[Clinical study on imipenem/cilastatin sodium in the field of pediatrics].
Topics: Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Infant; Infusions, Intravenous; Kinetics; Male; Thienamycins | 1986 |
[Fundamental and clinical studies on imipenem/cilastatin sodium in the field of pediatrics].
Topics: Bacteria; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Infusions, Intravenous; Kinetics; Male; Thienamycins | 1986 |
[Studies on imipenem/cilastatin sodium in the field of pediatrics].
Topics: Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Infusions, Intravenous; Kinetics; Male; Thienamycins | 1986 |
[Laboratory and clinical studies of imipenem/cilastatin sodium in the pediatric field].
Topics: Bacteria; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Infant; Kinetics; Male; Respiratory Tract Infections; Thienamycins | 1986 |
[Pharmacokinetic and clinical studies with imipenem/cilastatin sodium in the pediatric field. Pediatric Study Group for Imipenem/Cilastatin Sodium].
Topics: Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Humans; Imipenem; Infant; Infusions, Intravenous; Kinetics; Thienamycins | 1986 |
[Pharmacokinetic and clinical studies of imipenem/cilastatin sodium in the pediatric field].
Topics: Adolescent; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Infant; Infusions, Intravenous; Kinetics; Male; Thienamycins | 1986 |
[Effect of imipenem/cilastatin sodium in thirty cases of bone and joint infection].
Topics: Adult; Aged; Arthritis, Infectious; Bacterial Infections; Bursitis; Child; Cilastatin; Combined Modality Therapy; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Infusions, Intravenous; Male; Middle Aged; Osteomyelitis; Tendinopathy; Thienamycins | 1986 |
Efficacy of imipenem/cilastatin in patients with severe bacterial infections.
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Humans; Imipenem; Middle Aged; Thienamycins | 1986 |
Imipenem/cilastatin as secondary therapy for infections in cancer patients.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Female; Humans; Imipenem; Leukocyte Count; Male; Middle Aged; Neoplasms; Neutrophils; Pneumonia; Sepsis; Thienamycins | 1986 |
Severe gram-negative infections in neutropenic children cured by imipenem/cilastatin in combination with an aminoglycoside.
Topics: Adolescent; Adult; Agranulocytosis; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Dipeptidases; Drug Therapy, Combination; Enterobacteriaceae; Female; Gram-Negative Bacteria; Humans; Imipenem; Intestines; Male; Neoplasms; Neutropenia; Thienamycins | 1986 |
Imipenem/cilastatin: a multicentre international study of its clinical efficacy, safety and potential as empirical therapy.
Topics: Adult; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Female; Humans; Imipenem; Male; Middle Aged; Thienamycins | 1986 |
The safety profile of imipenem/cilastatin: worldwide clinical experience based on 3470 patients.
Topics: Bacterial Infections; Blood Cell Count; Cilastatin; Cyclopropanes; Dipeptidases; Gastrointestinal Diseases; Humans; Imipenem; Thienamycins | 1986 |
Clinical efficacy, safety and tolerability of intramuscular imipenem/cilastatin in the treatment of mild to moderate infections.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Female; Humans; Imipenem; Injections, Intramuscular; Male; Middle Aged; Thienamycins | 1986 |
Imipenem/cilastatin treatment of lower extremity skin and soft tissue infections in diabetics.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Diabetes Complications; Drug Combinations; Drug Evaluation; Female; Foot Diseases; Humans; Imipenem; Leg; Male; Middle Aged; Skin Diseases, Infectious; Thienamycins | 1987 |
Pharmacokinetic and clinical evaluation of imipenem/cilastatin in children and neonates.
Topics: Adolescent; Age Factors; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation; Female; Half-Life; Humans; Imipenem; Infant, Newborn; Male; Thienamycins | 1987 |
Intramuscular imipenem/cilastatin for treatment of mild and moderately severe bacterial infections.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Injections, Intramuscular; Male; Microbial Sensitivity Tests; Middle Aged; Thienamycins | 1987 |
[A clinical study on imipenem/cilastatin sodium in the field of pediatrics].
Topics: Bacterial Infections; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Escherichia coli Infections; Female; Gastroenteritis; Haemophilus Infections; Humans; Imipenem; Infant; Male; Neisseria; Respiratory Tract Infections; Streptococcal Infections; Thienamycins; Urinary Tract Infections | 1986 |
[Basic and clinical studies on imipenem/cilastatin sodium in the pediatric field].
Topics: Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Escherichia coli; Female; Humans; Imipenem; Infant; Kinetics; Male; Staphylococcus aureus; Thienamycins | 1986 |
[Treatment of moderate or severe infections using imipenem/cilastatin. 41 cases based on a multicenter protocol].
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Middle Aged; Recurrence; Thienamycins | 1986 |
Primaxin: an antibiotic for (nearly) all bacterial infections.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Drug Combinations; Humans; Imipenem; Thienamycins | 1987 |
[Hemostatic parameters influenced by imipenem/cilastatin].
Topics: Adult; Bacterial Infections; Blood Coagulation; Blood Platelets; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Male; Middle Aged; Platelet Aggregation; Thienamycins | 1986 |
[Dosage of imipenem/cilastatin].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Imipenem; Male; Middle Aged; Retrospective Studies; Thienamycins | 1986 |
[Efficacy and tolerance of imipenem/cilastatin in the treatment of surgical infections with and without bone involvement].
Topics: Adolescent; Adult; Aged; Bacterial Infections; Bone Diseases; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Male; Middle Aged; Postoperative Complications; Prospective Studies; Thienamycins | 1986 |
[Calculated initial chemotherapy in mechanically-ventilated postoperative patients with peritonitis, sepsis and pneumonia].
Topics: Adult; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Male; Middle Aged; Peritonitis; Pneumonia; Postoperative Complications; Respiration, Artificial; Retrospective Studies; Sepsis; Thienamycins | 1986 |
[Imipenem/cilastatin in surgical intensive medicine].
Topics: Abdomen; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Intensive Care Units; Male; Middle Aged; Postoperative Complications; Respiratory Tract Infections; Thienamycins; Urinary Tract Infections | 1986 |
[Treatment of respiratory tract infections with imipenem/cilastatin in critical patients with respiratory insufficiency].
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Cross Infection; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Male; Middle Aged; Prospective Studies; Respiration, Artificial; Respiratory Insufficiency; Respiratory Tract Infections; Thienamycins | 1986 |
Imipenem-cilastatin sodium.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Drug Combinations; Humans; Imipenem; Microbial Sensitivity Tests; Thienamycins | 1986 |
Early clinical experience with imipenem-cilistatin.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Microbial Sensitivity Tests; Middle Aged; Respiratory Tract Infections; Thienamycins; Urinary Tract Infections | 1985 |
Imipenem/cilastatin in the treatment of osteomyelitis.
Topics: Adult; Aged; Bacteria; Bacterial Infections; Bone and Bones; Cilastatin; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Male; Middle Aged; Osteomyelitis; Thienamycins | 1985 |
Pneumonia treated with imipenem/cilastatin.
Topics: Adult; Aged; Bacteria; Bacterial Infections; Cilastatin; Cross Infection; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Male; Middle Aged; Pneumonia; Pseudomonas Infections; Thienamycins | 1985 |
Imipenem/cilastatin: general experience in a community hospital.
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Drug Combinations; Female; Hospitals, Community; Humans; Imipenem; Male; Middle Aged; Respiratory Tract Infections; Thienamycins; Urinary Tract Infections | 1985 |
Role for newer beta-lactam antibiotics in treatment of osteomyelitis.
Topics: Adult; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cefotaxime; Ceftizoxime; Cilastatin; Cyclopropanes; Drug Combinations; Drug Resistance, Microbial; Humans; Imipenem; Osteomyelitis; Thienamycins | 1985 |
Imipenem/cilastatin in the treatment of obstetric and gynecologic infections.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Drug Combinations; Female; Genital Diseases, Female; Humans; Imipenem; Middle Aged; Pregnancy; Pregnancy Complications, Infectious; Thienamycins | 1985 |
Safety and efficacy of high-dose treatment with imipenem-cilastatin in seriously ill patients.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cyclopropanes; Dipeptidases; Drug Combinations; Female; Humans; Imipenem; Male; Microbial Sensitivity Tests; Middle Aged; Thienamycins | 1985 |
Imipenem/cilastatin efficacy evaluated.
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Middle Aged; Thienamycins | 1985 |
Penetration of imipenem and cilastatin into cerebrospinal fluid of patients with bacterial meningitis.
Topics: Adult; Aged; Bacterial Infections; Cilastatin; Cyclopropanes; Female; Humans; Imipenem; Male; Meningitis; Middle Aged; Thienamycins | 1985 |
Imipenem/cilastatin for the treatment of infections in hospitalized children.
Topics: Arthritis, Infectious; Bacterial Infections; Cellulitis; Child; Child, Preschool; Cilastatin; Cyclopropanes; Dipeptidases; Drug Combinations; Escherichia coli Infections; Female; Haemophilus Infections; Hospitalization; Humans; Imipenem; Infant; Kidney Diseases; Lymphadenitis; Male; Prospective Studies; Pseudomonas Infections; Staphylococcal Infections; Streptococcal Infections; Thienamycins; Wound Infection | 1985 |