Compounds > cilastatin
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cilastatin and Appendicitis

cilastatin has been researched along with Appendicitis in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's6 (66.67)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Babinchak, T; Campos, M; Ellis-Grosse, EJ; Loh, E; Oliva, ME; Pasternak, J; Rekha, A; Rose, GM; Yellin, A1
Mallick, R; Schell, SR; Sun, S1
Akamo, Y; Manabe, T; Mizokami, M; Mizuno, I; Mohri, N; Shinagawa, N; Takeyama, H; Yuasa, H1
Barie, PS; Baumgartner, TF; Dellinger, EP; Rotstein, OD; Solomkin, JS; Vogel, SB; Yang, JY1
Faulkner, K; Wilson, SE1
Allo, MD; Bennion, RS; Finegold, SM; Kathir, K; Lentz, M; Meute, M; Thompson, JE1
Heikkinen, E; Seppänen, J; Uhari, M1
Appleman, MD; Berne, TV; Chenella, FC; Gill, MA; Heseltine, PN; Yellin, AE1
Appleman, MD; Berne, TV; Chenella, FC; Gill, MA; Heseltine, PN; Leedom, JM; Yellin, AE1

Trials

7 trial(s) available for cilastatin and Appendicitis

ArticleYear
A multicenter trial of the efficacy and safety of tigecycline versus imipenem/cilastatin in patients with complicated intra-abdominal infections [Study ID Numbers: 3074A1-301-WW; ClinicalTrials.gov Identifier: NCT00081744].
    BMC infectious diseases, 2005, Oct-19, Volume: 5

    Topics: Abdomen; Adult; Anti-Bacterial Agents; Appendicitis; Bacterial Infections; Cholecystitis; Cilastatin; Cilastatin, Imipenem Drug Combination; Diverticulitis; Double-Blind Method; Drug Combinations; Female; Humans; Imipenem; Intestinal Perforation; Male; Middle Aged; Minocycline; Peptic Ulcer Perforation; Peritonitis; Tigecycline

2005
Predictors of efficacy and health resource utilization in treatment of complicated intra-abdominal infections: evidence for pooled clinical studies comparing tigecycline with imipenem-cilastatin.
    Surgical infections, 2007, Volume: 8, Issue:2

    Topics: Abdominal Abscess; Aged; Anti-Bacterial Agents; APACHE; Appendicitis; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials, Phase III as Topic; Digestive System Surgical Procedures; Double-Blind Method; Drug Combinations; Female; Health Resources; Humans; Imipenem; Length of Stay; Male; Middle Aged; Minocycline; Postoperative Complications; Reoperation; Risk Factors; Tigecycline

2007
A randomized, double-blind clinical trial comparing cefepime plus metronidazole with imipenem-cilastatin in the treatment of complicated intra-abdominal infections. Cefepime Intra-abdominal Infection Study Group.
    Archives of surgery (Chicago, Ill. : 1960), 1997, Volume: 132, Issue:12

    Topics: Abdomen; Abdominal Abscess; Adult; Aged; Antitrichomonal Agents; Appendicitis; Cefepime; Cephalosporins; Cilastatin; Double-Blind Method; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Imipenem; Infections; Male; Metronidazole; Middle Aged; Peritonitis; Treatment Outcome

1997
Impact an anatomical site on bacteriological and clinical outcome in the management of intra-abdominal infections.
    The American surgeon, 1998, Volume: 64, Issue:5

    Topics: Adult; Aged; Anti-Bacterial Agents; Appendicitis; Bacterial Infections; Bacteriological Techniques; Cause of Death; Cilastatin; Clindamycin; Combined Modality Therapy; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Imipenem; Male; Meropenem; Middle Aged; Peritonitis; Risk Factors; Survival Rate; Thienamycins; Tobramycin; Treatment Outcome

1998
Ticarcillin/clavulanate versus imipenem/cilistatin for the treatment of infections associated with gangrenous and perforated appendicitis.
    The American surgeon, 1999, Volume: 65, Issue:2

    Topics: Adolescent; Adult; Aged; Appendicitis; Appendix; Child; Cilastatin; Cilastatin, Imipenem Drug Combination; Clavulanic Acids; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Gangrene; Humans; Imipenem; Intestinal Perforation; Male; Middle Aged; Prospective Studies; Ticarcillin; Treatment Outcome

1999
Imipenem-cilastatin vs. tobramycin and metronidazole for appendicitis-related infections.
    The Pediatric infectious disease journal, 1992, Volume: 11, Issue:6

    Topics: Adolescent; Anti-Bacterial Agents; Appendicitis; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Infant; Male; Metronidazole; Tobramycin

1992
Intramuscular imipenem as adjuvant therapy for acute cholecystitis and perforated or gangrenous appendicitis.
    Chemotherapy, 1991, Volume: 37 Suppl 2

    Topics: Adult; Appendicitis; Cholecystitis; Cilastatin; Cilastatin, Imipenem Drug Combination; Combined Modality Therapy; Drug Combinations; Female; Gangrene; Half-Life; Humans; Imipenem; Injections, Intramuscular; Intestinal Perforation; Lidocaine; Male; Prospective Studies; Rupture, Spontaneous

1991

Other Studies

2 other study(ies) available for cilastatin and Appendicitis

ArticleYear
Perforated acute appendicitis in a patient with AIDS/HIV infection: report of a case.
    Surgery today, 1995, Volume: 25, Issue:1

    Topics: Acute Disease; Adult; AIDS-Related Opportunistic Infections; Appendectomy; Appendicitis; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Escherichia coli Infections; Fever of Unknown Origin; Granulocyte Colony-Stimulating Factor; Humans; Imipenem; Immunization, Passive; Intestinal Perforation; Male; Postoperative Complications; Rupture, Spontaneous

1995
Imipenem therapy for perforated and gangrenous appendicitis.
    Surgery, gynecology & obstetrics, 1986, Volume: 162, Issue:1

    Topics: Adult; Aged; Appendectomy; Appendicitis; Ascitic Fluid; Cilastatin; Clindamycin; Cyclopropanes; Drug Resistance, Microbial; Drug Therapy, Combination; Fever; Gangrene; Gentamicins; Humans; Imipenem; Intestinal Perforation; Length of Stay; Middle Aged; Rupture, Spontaneous; Thienamycins

1986