Compounds > cilastatin
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cilastatin and Acute Kidney Failure

cilastatin has been researched along with Acute Kidney Failure in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.00)18.7374
1990's7 (35.00)18.2507
2000's2 (10.00)29.6817
2010's4 (20.00)24.3611
2020's4 (20.00)2.80

Authors

AuthorsStudies
Gómez-Gómez, MM; Lázaro, A; Marazuela, MD; Moreno-Gordaliza, E; Pastor, Ó1
Cui, L; Han, J; Hu, F; Wang, R; Yu, F; Yuan, H1
Andeen, NK; Eiwaz, MB; Groat, T; Hebert, JF; Hutchens, MP; Munhall, AC; Nickerson, MN; Pai, AA1
Eiwaz, MB; Funahashi, Y; Hebert, JF; Hutchens, MP; Matsushita, K; McCormick, JA; Mori, K; Munhall, AC; Nickerson, MN; Saritas, T; Yanagita, M1
Bonventre, JV; Camaño, S; González-Nicolás, MÁ; Humanes, B; Lara, JM; Lázaro, A; Sabbisetti, V; Tejedor, A1
Gil, HW; Hwang, HS; Im, DS; Jung, SY; Shin, HJ; Song, HY; Yang, KJ1
Branski, LK; Cambiaso-Daniel, J; Capek, KD; De Crescenzo, A; Finnerty, CC; Herndon, DN; Hundeshagen, G; Killion, EA; Kinsky, MP; Mlcak, RP; Norbury, WB; Sljivich, M; Voigt, CD1
Gil, HW; Hwang, HS; Im, DS; Jin, J; Jin, L; Lim, SW; Luo, K; Yang, CW1
Brett, S; Cotton, A; Franklin, BD; Holmes, A1
Caramelo, C; Castilla, M; de Lucas, C; Lazaro, JA; Tejedor, A; Torres, AM1
Macias, WL; Mueller, BA; Scarim, SK1
Dehne, MG; Kroh, UF1
Bernis, C; Fernández-Rañada, JM; Gruss, E; Rodriguez, F; Tomás, JF; Traver, JA1
Bremer, F; Brune, K; Geisslinger, G; Oelkers, R; Schobel, H; Schüttler, J; Tegeder, I1
Vincent, HH; Vos, MC; Yzerman, EP1
Bengel, D; Przechera, M; Risler, T1
Horowitz, E; Lee, HC; Linder, W1
Böhler, J; Fecht, H; Keller, E; Schollmeyer, P1
Keller, E1
Schliamser, SE1

Reviews

3 review(s) available for cilastatin and Acute Kidney Failure

ArticleYear
Using imipenem and cilastatin during continuous renal replacement therapy.
    Pharmacy world & science : PWS, 2005, Volume: 27, Issue:5

    Topics: Acute Kidney Injury; Anti-Bacterial Agents; Cilastatin; Drug Administration Schedule; Drug Therapy, Combination; Female; Hemofiltration; Humans; Imipenem; Male; Middle Aged; Protease Inhibitors

2005
Cilastatin protection against cyclosporin A-induced nephrotoxicity: clinical evidence.
    Current medical research and opinion, 2007, Volume: 23, Issue:3

    Topics: Acute Kidney Injury; Cilastatin; Creatinine; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Imipenem; Kidney Function Tests; Male; Probability; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome

2007
Drug therapy during continuous arteriovenous hemofiltration.
    Advances in experimental medicine and biology, 1989, Volume: 260

    Topics: Acute Kidney Injury; Cilastatin; Hemofiltration; Humans; Imipenem; Metabolic Clearance Rate

1989

Trials

2 trial(s) available for cilastatin and Acute Kidney Failure

ArticleYear
Imipenem/cilastin dosage during acute renal failure and hemofiltration.
    Intensive care medicine, 1995, Volume: 21, Issue:10

    Topics: Acute Kidney Injury; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Monitoring; Drug Therapy, Combination; Hemofiltration; Humans; Imipenem

1995
Nephroprotective effect of cilastatin in allogeneic bone marrow transplantation. Results from a retrospective analysis.
    Bone marrow transplantation, 1996, Volume: 18, Issue:4

    Topics: Acute Kidney Injury; Adult; Bone Marrow Transplantation; Cilastatin; Cyclosporine; Female; Graft vs Host Disease; Humans; Imipenem; Immunosuppressive Agents; Kidney; Leukemia; Male; Protease Inhibitors; Retrospective Studies; Transplantation, Homologous

1996

Other Studies

15 other study(ies) available for cilastatin and Acute Kidney Failure

ArticleYear
Lipidomics Reveals Cisplatin-Induced Renal Lipid Alterations during Acute Kidney Injury and Their Attenuation by Cilastatin.
    International journal of molecular sciences, 2021, Nov-20, Volume: 22, Issue:22

    Topics: Acute Kidney Injury; Animals; Apoptosis; Chromatography, Liquid; Cilastatin; Cisplatin; Glomerular Filtration Rate; Humans; Kidney; Lipid Metabolism; Lipidomics; Lipids; Rats; Tandem Mass Spectrometry

2021
Megalin blockade with cilastatin ameliorates multiple wasp sting-induced acute kidney injury in rats.
    Toxicon : official journal of the International Society on Toxinology, 2022, Volume: 220

    Topics: Acute Kidney Injury; Animals; Biomarkers; Cilastatin; Creatine Kinase; Insect Bites and Stings; Kidney; Low Density Lipoprotein Receptor-Related Protein-2; Male; Mice; Myoglobin; Rats; Rats, Wistar; Rhabdomyolysis; Wasp Venoms; Wasps

2022
Legal Performance-enhancing Drugs Alter Course and Treatment of Rhabdomyolysis-induced Acute Kidney Injury.
    Military medicine, 2023, 11-08, Volume: 188, Issue:Suppl 6

    Topics: Acute Kidney Injury; Animals; Caffeine; Cilastatin; Glycerol; Humans; Ibuprofen; Mice; Performance-Enhancing Substances; Rhabdomyolysis

2023
Cilastatin Ameliorates Rhabdomyolysis-induced AKI in Mice.
    Journal of the American Society of Nephrology : JASN, 2021, Volume: 32, Issue:10

    Topics: Acute Kidney Injury; Animals; Apoptosis; Blood Urea Nitrogen; Cilastatin; Disease Models, Animal; Endocytosis; Glomerular Filtration Rate; Kidney Tubules, Proximal; Low Density Lipoprotein Receptor-Related Protein-2; Male; Mice; Mice, Knockout; Myoglobin; Myoglobinuria; Protease Inhibitors; Rhabdomyolysis

2021
Cisplatin-induced renal inflammation is ameliorated by cilastatin nephroprotection.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2017, Oct-01, Volume: 32, Issue:10

    Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Apoptosis; Blood Urea Nitrogen; Cilastatin; Cisplatin; Creatinine; Cytokines; Drug Evaluation, Preclinical; Glomerular Filtration Rate; Kidney Tubules, Proximal; Male; Nephritis; NF-kappa B; Protease Inhibitors; Rats; Rats, Wistar

2017
Cilastatin attenuates vancomycin-induced nephrotoxicity via P-glycoprotein.
    Toxicology letters, 2017, Aug-05, Volume: 277

    Topics: Acute Kidney Injury; Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Cell Line; Cell Proliferation; Cilastatin; Cytoprotection; Dose-Response Relationship, Drug; Humans; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Signal Transduction; Time Factors; Vancomycin

2017
Co-administration of vancomycin and piperacillin-tazobactam is associated with increased renal dysfunction in adult and pediatric burn patients.
    Critical care (London, England), 2017, 12-20, Volume: 21, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Adult; Analysis of Variance; Anti-Bacterial Agents; Burns; Child; Child, Preschool; Cilastatin; Cilastatin, Imipenem Drug Combination; Cohort Studies; Creatinine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Incidence; Infections; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Texas; Vancomycin

2017
Cilastatin protects against tacrolimus-induced nephrotoxicity via anti-oxidative and anti-apoptotic properties.
    BMC nephrology, 2019, 06-14, Volume: 20, Issue:1

    Topics: Acute Kidney Injury; Animals; Apoptosis; Cilastatin; Humans; Immunosuppressive Agents; Male; Oxidative Stress; Protease Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; Tacrolimus

2019
Comparison of imipenem pharmacokinetics in patients with acute or chronic renal failure treated with continuous hemofiltration.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1993, Volume: 21, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Anti-Bacterial Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Hemofiltration; Humans; Imipenem; Kidney; Kidney Failure, Chronic; Male; Middle Aged

1993
Pharmacokinetics of imipenem-cilastatin in critically ill patients undergoing continuous venovenous hemofiltration.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:12

    Topics: Acute Kidney Injury; Adult; Aged; Area Under Curve; Cilastatin; Cilastatin, Imipenem Drug Combination; Computer Simulation; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Hemofiltration; Humans; Imipenem; Liver; Male; Middle Aged

1997
Clearance of imipenem/cilastatin in acute renal failure patients treated by continuous hemodiafiltration (CAVHD).
    Intensive care medicine, 1992, Volume: 18, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Cilastatin; Drug Combinations; Female; Half-Life; Hemofiltration; Humans; Imipenem; Male; Metabolic Clearance Rate; Middle Aged; Reference Standards

1992
Pharmacokinetics of imipenem/cilastatin during continuous arteriovenous hemofiltration.
    Contributions to nephrology, 1991, Volume: 93

    Topics: Acute Kidney Injury; Adult; Aged; Bacterial Infections; Cilastatin; Cross Infection; Drug Therapy, Combination; Female; Half-Life; Hemofiltration; Humans; Imipenem; Male; Metabolic Clearance Rate; Middle Aged

1991
Treatment of tularemia with imipenem/cilastatin sodium.
    Southern medical journal, 1991, Volume: 84, Issue:10

    Topics: Acute Kidney Injury; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Humans; Imipenem; Male; Middle Aged; Tularemia

1991
Single-dose kinetics of imipenem/cilastatin during continuous arteriovenous haemofiltration in intensive care patients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1989, Volume: 4, Issue:7

    Topics: Acute Kidney Injury; Adult; Aged; Bacterial Infections; Cilastatin; Critical Care; Drug Therapy, Combination; Female; Hemofiltration; Humans; Imipenem; Male; Middle Aged

1989
Neurotoxicity of beta-lactam antibiotics. Experimental kinetic and neurophysiological studies.
    Scandinavian journal of infectious diseases. Supplementum, 1988, Volume: 55

    Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Blood-Brain Barrier; Brain; Carbapenems; Cilastatin; Drug Interactions; Electroencephalography; Enterobacteriaceae Infections; Female; Hippocampus; Imipenem; Male; Meningitis; Penicillin G; Rabbits; Rats; Rats, Inbred Strains; Seizures; Thiopental; Tissue Distribution; Uremia

1988