Page last updated: 2024-10-25

ciglitazone and Prostatic Neoplasms

ciglitazone has been researched along with Prostatic Neoplasms in 8 studies

ciglitazone: structure given in second source; PPAR agonist used for type II diabetes
ciglitazone : An aromatic ether that consists of 1,3-thiazolidine-2,4-dione with position 5 substituted by a 4-[(1-methylcyclohexyl)methoxy]benzyl group. A selective PPARgamma agonist.

Prostatic Neoplasms: Tumors or cancer of the PROSTATE.

Research Excerpts

ExcerptRelevanceReference
"The PPAR-gamma ligands, 15-deoxy-Delta(12,14)-prostaglandin J(2) and ciglitazone, and the PPAR-alpha ligand, WY-14643, were examined for their effects on proliferation and apoptosis of A375 melanoma, DU145 and PC3 prostate cancer, and MB-MDA-231 breast cancer."3.73PPAR-gamma ligands and amino acid deprivation promote apoptosis of melanoma, prostate, and breast cancer cells. ( Liu, H; Meadows, GG; Núñez, NP, 2006)
"Human prostate cancer cells were used."1.33Does the PGC-1/PPARgamma pathway play a role in Com-1/p8 mediated cell growth inhibition in prostate cancer? ( Davies, G; Fodstad, O; Jiang, WG; Kynaston, H; Mason, MD, 2006)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lyles, BE2
Akinyeke, TO1
Moss, PE2
Stewart, LV2
Gottfried, E1
Rogenhofer, S1
Waibel, H1
Kunz-Schughart, LA1
Reichle, A1
Wehrstein, M1
Peuker, A1
Peter, K1
Hartmannsgruber, G1
Andreesen, R1
Kreutz, M1
Chen, CH1
Huang, PH1
Chu, PC1
Chen, MC1
Chou, CC1
Wang, D1
Kulp, SK1
Teng, CM1
Wang, Q1
Chen, CS3
Núñez, NP1
Liu, H1
Meadows, GG1
Yang, CC1
Ku, CY1
Wei, S1
Shiau, CW1
Pinzone, JJ1
Ringel, MD1
Jiang, WG1
Davies, G1
Kynaston, H1
Mason, MD1
Fodstad, O1
Laidler, P1
Dulińska, J1
Mrozicki, S1

Other Studies

8 other studies available for ciglitazone and Prostatic Neoplasms

ArticleYear
Thiazolidinediones regulate expression of cell cycle proteins in human prostate cancer cells via PPARgamma-dependent and PPARgamma-independent pathways.
    Cell cycle (Georgetown, Tex.), 2009, Jan-15, Volume: 8, Issue:2

    Topics: Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase Inhibi

2009
Pioglitazone modulates tumor cell metabolism and proliferation in multicellular tumor spheroids.
    Cancer chemotherapy and pharmacology, 2011, Volume: 67, Issue:1

    Topics: Cell Line, Tumor; Cell Proliferation; Chromans; Deoxyglucose; Humans; Hydrogen-Ion Concentration; Hy

2011
The PPARγ ligand ciglitazone regulates androgen receptor activation differently in androgen-dependent versus androgen-independent human prostate cancer cells.
    Experimental cell research, 2010, Dec-10, Volume: 316, Issue:20

    Topics: Androgen-Binding Protein; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Dihydrotestosterone; Gene

2010
Energy restriction-mimetic agents induce apoptosis in prostate cancer cells in part through epigenetic activation of KLF6 tumor suppressor gene expression.
    The Journal of biological chemistry, 2011, Mar-25, Volume: 286, Issue:12

    Topics: Acetylation; Apoptosis; Cell Line, Tumor; Epigenesis, Genetic; Gene Expression Regulation, Neoplasti

2011
PPAR-gamma ligands and amino acid deprivation promote apoptosis of melanoma, prostate, and breast cancer cells.
    Cancer letters, 2006, May-08, Volume: 236, Issue:1

    Topics: Amino Acids; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferatio

2006
Peroxisome proliferator-activated receptor gamma-independent repression of prostate-specific antigen expression by thiazolidinediones in prostate cancer cells.
    Molecular pharmacology, 2006, Volume: 69, Issue:5

    Topics: Animals; Cell Line, Tumor; Dihydrotestosterone; Humans; Male; Pioglitazone; PPAR gamma; Prostate-Spe

2006
Does the PGC-1/PPARgamma pathway play a role in Com-1/p8 mediated cell growth inhibition in prostate cancer?
    International journal of molecular medicine, 2006, Volume: 18, Issue:6

    Topics: Basic Helix-Loop-Helix Transcription Factors; Cell Division; Cell Line, Tumor; DNA, Complementary; G

2006
Does the inhibition of c-myc expression mediate the anti-tumor activity of PPAR's ligands in prostate cancer cell lines?
    Archives of biochemistry and biophysics, 2007, Jun-01, Volume: 462, Issue:1

    Topics: Anilides; Antineoplastic Agents; Apoptosis; beta Catenin; Cadherins; Cell Differentiation; Cell Line

2007