ciglitazone has been researched along with Leukemia, Promyelocytic, Acute in 1 studies
ciglitazone: structure given in second source; PPAR agonist used for type II diabetes
ciglitazone : An aromatic ether that consists of 1,3-thiazolidine-2,4-dione with position 5 substituted by a 4-[(1-methylcyclohexyl)methoxy]benzyl group. A selective PPARgamma agonist.
Leukemia, Promyelocytic, Acute: An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present study we investigated the in vitro apoptosis inducing effects of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligand ciglitazone (CGZ) on acute promyelocytic leukemia (APL) NB4 cells and its mechanisms of action." | 3.75 | Activation of peroxisome proliferator-activated receptor-gamma induces apoptosis on acute promyelocytic leukemia cells via downregulation of XIAP. ( Fang, ZG; Guo, YW; He, Y; Huang, RW; Li, XD; Lin, DJ; Liu, JJ; Liu, PQ; Si, XN; Wang, CZ; Wu, XY; Xiao, RZ; Xu, Y, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, JJ | 1 |
| Guo, YW | 1 |
| Fang, ZG | 1 |
| Si, XN | 1 |
| Wu, XY | 1 |
| Liu, PQ | 1 |
| Lin, DJ | 1 |
| Xiao, RZ | 1 |
| Xu, Y | 1 |
| Wang, CZ | 1 |
| Li, XD | 1 |
| He, Y | 1 |
| Huang, RW | 1 |
1 other study available for ciglitazone and Leukemia, Promyelocytic, Acute
| Article | Year |
|---|---|
Activation of peroxisome proliferator-activated receptor-gamma induces apoptosis on acute promyelocytic leukemia cells via downregulation of XIAP.
Topics: Anilides; Aniline Compounds; Apoptosis; Blotting, Western; Caspase 3; Cell Line, Tumor; Cell Prolife | 2009 |