ciglitazone has been researched along with Fibroid in 3 studies
ciglitazone: structure given in second source; PPAR agonist used for type II diabetes
ciglitazone : An aromatic ether that consists of 1,3-thiazolidine-2,4-dione with position 5 substituted by a 4-[(1-methylcyclohexyl)methoxy]benzyl group. A selective PPARgamma agonist.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response studies on proliferation found that uterine leiomyoma was more sensitive to inhibition by ciglitizone treatments than normal myometrium." | 1.34 | Growth inhibition and apoptosis induced in human leiomyoma cells by treatment with the PPAR gamma ligand ciglitizone. ( Bae, I; Cha, SD; Cho, CH; Jeon, DS; Kwon, KY; Kwon, SH; Nam, DH; Ramachandran, S; Shin, SJ; Song, DK, 2007) |
| "Human leiomyomas were also found to express all three PPAR isoforms, and primary cultures of these cells were sensitive to the inhibitory effects of PPARgamma ligands." | 1.32 | Inhibition of proliferation and estrogen receptor signaling by peroxisome proliferator-activated receptor gamma ligands in uterine leiomyoma. ( Broaddus, RR; Copland, JA; Fischer, SM; Gottardis, MM; Houston, KD; Walker, CL, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Houston, KD | 1 |
| Copland, JA | 1 |
| Broaddus, RR | 1 |
| Gottardis, MM | 1 |
| Fischer, SM | 1 |
| Walker, CL | 1 |
| Kim, BY | 1 |
| Cho, CH | 2 |
| Song, DK | 2 |
| Mun, KC | 1 |
| Suh, SI | 1 |
| Kim, SP | 1 |
| Shin, DH | 1 |
| Jang, BC | 1 |
| Kwon, TK | 1 |
| Cha, SD | 2 |
| Bae, I | 2 |
| Bae, JH | 1 |
| Nam, DH | 1 |
| Ramachandran, S | 1 |
| Kwon, KY | 1 |
| Jeon, DS | 1 |
| Shin, SJ | 1 |
| Kwon, SH | 1 |
3 other studies available for ciglitazone and Fibroid
| Article | Year |
|---|---|
Inhibition of proliferation and estrogen receptor signaling by peroxisome proliferator-activated receptor gamma ligands in uterine leiomyoma.
Topics: Animals; Cell Division; Chromans; Docosahexaenoic Acids; Estradiol; Female; Humans; Leiomyoma; Ligan | 2003 |
Ciglitizone inhibits cell proliferation in human uterine leiomyoma via activation of store-operated Ca2+ channels.
Topics: Calcium; Calcium Channels; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Fe | 2005 |
Growth inhibition and apoptosis induced in human leiomyoma cells by treatment with the PPAR gamma ligand ciglitizone.
Topics: Apoptosis; Blotting, Western; Caspase 8; Cell Cycle; Cell Proliferation; Dose-Response Relationship, | 2007 |