ciglitazone has been researched along with Diabetes Mellitus in 4 studies
ciglitazone: structure given in second source; PPAR agonist used for type II diabetes
ciglitazone : An aromatic ether that consists of 1,3-thiazolidine-2,4-dione with position 5 substituted by a 4-[(1-methylcyclohexyl)methoxy]benzyl group. A selective PPARgamma agonist.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Chronic administration of ADD-3878 for as long as 12 wk to young yellow KK mice, which were in the early stage of diabetes and obesity, depressed age-dependent rises in blood glucose, plasma triglyceride, and insulin without exerting any effect on obesity." | 5.27 | Reduction of insulin resistance in obese and/or diabetic animals by 5-[4-(1-methylcyclohexylmethoxy)benzyl]-thiazolidine-2,4-dione (ADD-3878, U-63,287, ciglitazone), a new antidiabetic agent. ( Fujita, T; Iwatsuka, H; Kawamatsu, Y; Sohda, T; Sugiyama, Y; Suzuoki, Z; Taketomi, S, 1983) |
| "Insulin resistance is a characteristic feature of type II diabetes as well as obesity." | 2.41 | [Discovery and development of a new insulin sensitizing agent, pioglitazone]. ( Fujita, T; Ikeda, H; Kawamatsu, Y; Meguro, K; Sohda, T, 2002) |
| " Chronic administration of ADD-3878 for as long as 12 wk to young yellow KK mice, which were in the early stage of diabetes and obesity, depressed age-dependent rises in blood glucose, plasma triglyceride, and insulin without exerting any effect on obesity." | 1.27 | Reduction of insulin resistance in obese and/or diabetic animals by 5-[4-(1-methylcyclohexylmethoxy)benzyl]-thiazolidine-2,4-dione (ADD-3878, U-63,287, ciglitazone), a new antidiabetic agent. ( Fujita, T; Iwatsuka, H; Kawamatsu, Y; Sohda, T; Sugiyama, Y; Suzuoki, Z; Taketomi, S, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Momose, Y | 1 |
| Maekawa, T | 1 |
| Yamano, T | 1 |
| Kawada, M | 1 |
| Odaka, H | 1 |
| Ikeda, H | 2 |
| Sohda, T | 3 |
| Kawamatsu, Y | 2 |
| Fujita, T | 2 |
| Meguro, K | 1 |
| Sugiyama, Y | 1 |
| Taketomi, S | 1 |
| Iwatsuka, H | 1 |
| Suzuoki, Z | 1 |
| Arakawa, K | 1 |
| Inamasu, M | 1 |
| Matsumoto, M | 1 |
| Okumura, K | 1 |
| Yasuda, K | 1 |
| Akatsuka, H | 1 |
| Kawanami, S | 1 |
| Watanabe, A | 1 |
| Homma, K | 1 |
| Saiga, Y | 1 |
| Ozeki, M | 1 |
| Iijima, I | 1 |
1 review available for ciglitazone and Diabetes Mellitus
| Article | Year |
|---|---|
[Discovery and development of a new insulin sensitizing agent, pioglitazone].
Topics: Animals; Clinical Trials as Topic; Clofibrate; Diabetes Mellitus; Diabetes Mellitus, Experimental; D | 2002 |
3 other studies available for ciglitazone and Diabetes Mellitus
| Article | Year |
|---|---|
Novel 5-substituted 2,4-thiazolidinedione and 2,4-oxazolidinedione derivatives as insulin sensitizers with antidiabetic activities.
Topics: Animals; Chromatography, High Pressure Liquid; COS Cells; Crystallography, X-Ray; Diabetes Mellitus; | 2002 |
Reduction of insulin resistance in obese and/or diabetic animals by 5-[4-(1-methylcyclohexylmethoxy)benzyl]-thiazolidine-2,4-dione (ADD-3878, U-63,287, ciglitazone), a new antidiabetic agent.
Topics: Animals; Blood Glucose; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dogs; Fatty | 1983 |
Novel benzoxazole 2,4-thiazolidinediones as potent hypoglycemic agents. Synthesis and structure-activity relationships.
Topics: Animals; Benzopyrans; Benzoxazoles; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hypoglyc | 1997 |