ciglitazone has been researched along with Cataract in 3 studies
ciglitazone: structure given in second source; PPAR agonist used for type II diabetes
ciglitazone : An aromatic ether that consists of 1,3-thiazolidine-2,4-dione with position 5 substituted by a 4-[(1-methylcyclohexyl)methoxy]benzyl group. A selective PPARgamma agonist.
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The cataractogenic potential of the thiazolidinedione ciglitazone (CIG) was investigated in vivo and in vitro." | 3.73 | Ciglitazone-induced lenticular opacities in rats: in vivo and whole lens explant culture evaluation. ( Aleo, MD; Doshna, CM; Navetta, KA, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sampath, S | 1 |
| McLean, LA | 1 |
| Buono, C | 1 |
| Moulin, P | 1 |
| Wolf, A | 1 |
| Chibout, SD | 1 |
| Pognan, F | 1 |
| Busch, S | 1 |
| Shangari, N | 1 |
| Cruz, E | 1 |
| Gurnani, M | 1 |
| Patel, P | 1 |
| Reising, A | 1 |
| Aleo, MD | 2 |
| Doshna, CM | 1 |
| Navetta, KA | 2 |
| Avery, MJ | 1 |
| Beierschmitt, WP | 1 |
| Drupa, CA | 1 |
| Fortner, JH | 1 |
| Kaplan, AH | 1 |
| Shepard, RM | 1 |
| Walsh, CM | 1 |
3 other studies available for ciglitazone and Cataract
| Article | Year |
|---|---|
The use of rat lens explant cultures to study the mechanism of drug-induced cataractogenesis.
Topics: Acetates; Animals; Cataract; Cell Survival; Eye Proteins; Gene Expression Profiling; Gene Expression | 2012 |
Ciglitazone-induced lenticular opacities in rats: in vivo and whole lens explant culture evaluation.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Cataract; Dogs; Dose-Response Relationship, Drug; Fema | 2005 |
The use of explant lens culture to assess cataractogenic potential.
Topics: Adenosine Triphosphate; Aminooxyacetic Acid; Animals; Benzopyrans; Biotransformation; Cataract; Drug | 2000 |