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ciglitazone and Cardiac Remodeling, Ventricular

ciglitazone has been researched along with Cardiac Remodeling, Ventricular in 2 studies

ciglitazone: structure given in second source; PPAR agonist used for type II diabetes
ciglitazone : An aromatic ether that consists of 1,3-thiazolidine-2,4-dione with position 5 substituted by a 4-[(1-methylcyclohexyl)methoxy]benzyl group. A selective PPARgamma agonist.

Research Excerpts

ExcerptRelevanceReference
" To test the hypothesis that PPARgamma decreased LVH and cardiac fibrosis in chronic pressure overload, in part, by increasing SOD, eNOS and elastin and decreasing NOX4, MMP and collagen synthesis and degradation, chronic pressure overload analogous to systemic hypertension was created in C57BL/6J mice by occluding the abdominal aorta above the kidneys (aortic stenosis-AS)."7.74Reversal of systemic hypertension-associated cardiac remodeling in chronic pressure overload myocardium by ciglitazone. ( Henderson, BC; Kartha, GK; Moshal, KS; Ovechkin, A; Reynolds, C; Rodriguez, WE; Sen, U; Tyagi, N; Tyagi, SC, 2007)
" To test the hypothesis that PPARgamma decreased LVH and cardiac fibrosis in chronic pressure overload, in part, by increasing SOD, eNOS and elastin and decreasing NOX4, MMP and collagen synthesis and degradation, chronic pressure overload analogous to systemic hypertension was created in C57BL/6J mice by occluding the abdominal aorta above the kidneys (aortic stenosis-AS)."3.74Reversal of systemic hypertension-associated cardiac remodeling in chronic pressure overload myocardium by ciglitazone. ( Henderson, BC; Kartha, GK; Moshal, KS; Ovechkin, A; Reynolds, C; Rodriguez, WE; Sen, U; Tyagi, N; Tyagi, SC, 2007)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tyagi, N2
Moshal, KS2
Lominadze, D1
Ovechkin, AV1
Tyagi, SC2
Henderson, BC1
Sen, U1
Reynolds, C1
Ovechkin, A1
Kartha, GK1
Rodriguez, WE1

Other Studies

2 other studies available for ciglitazone and Cardiac Remodeling, Ventricular

ArticleYear
Homocysteine-dependent cardiac remodeling and endothelial-myocyte coupling in a 2 kidney, 1 clip Goldblatt hypertension mouse model.
    Canadian journal of physiology and pharmacology, 2005, Volume: 83, Issue:7

    Topics: Acetylcholine; Animals; Blotting, Western; Collagen; Endothelin-1; Endothelium, Vascular; Fibrosis;

2005
Reversal of systemic hypertension-associated cardiac remodeling in chronic pressure overload myocardium by ciglitazone.
    International journal of biological sciences, 2007, Sep-07, Volume: 3, Issue:6

    Topics: Animals; Collagen; Elastin; Fibrosis; Heart; Hypertension; Hypertrophy, Left Ventricular; Hypoglycem

2007