Page last updated: 2024-10-25

ciglitazone and Brain Neoplasms

ciglitazone has been researched along with Brain Neoplasms in 4 studies

ciglitazone: structure given in second source; PPAR agonist used for type II diabetes
ciglitazone : An aromatic ether that consists of 1,3-thiazolidine-2,4-dione with position 5 substituted by a 4-[(1-methylcyclohexyl)methoxy]benzyl group. A selective PPARgamma agonist.

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
" The present study was undertaken to determine the precise mechanism of cell death induced by ciglitazone, a synthetic PPAR gamma agonist, in A172 human glioma cells."7.74Ciglitazone induces caspase-independent apoptosis through down-regulation of XIAP and survivin in human glioma cells. ( Choi, CH; Kang, DW; Kang, SK; Kim, YK; Park, JY, 2008)
" The present study was undertaken to determine the precise mechanism of cell death induced by ciglitazone, a synthetic PPAR gamma agonist, in A172 human glioma cells."3.74Ciglitazone induces caspase-independent apoptosis through down-regulation of XIAP and survivin in human glioma cells. ( Choi, CH; Kang, DW; Kang, SK; Kim, YK; Park, JY, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ehrmann, J2
Strakova, N2
Vrzalikova, K1
Hezova, R1
Kolar, Z2
Bartos, J1
Malikova, J1
Dolezel, J1
Lenman, A1
Fowler, CJ1
Kang, DW1
Choi, CH1
Park, JY1
Kang, SK1
Kim, YK1

Other Studies

4 other studies available for ciglitazone and Brain Neoplasms

ArticleYear
Expression of STATs and their inhibitors SOCS and PIAS in brain tumors. In vitro and in vivo study.
    Neoplasma, 2008, Volume: 55, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Gene Expression; Glioblastoma; Humans; Molecular Chaperones; Phos

2008
Peroxisome proliferator-activated receptors (PPAR) agonists affect cell viability, apoptosis and expression of cell cycle related proteins in cell lines of glial brain tumors.
    Neoplasma, 2005, Volume: 52, Issue:2

    Topics: Apoptosis; Bezafibrate; Brain Neoplasms; Cell Cycle; Cell Differentiation; Cell Survival; Flow Cytom

2005
Interaction of ligands for the peroxisome proliferator-activated receptor gamma with the endocannabinoid system.
    British journal of pharmacology, 2007, Volume: 151, Issue:8

    Topics: Amidohydrolases; Animals; Anti-Inflammatory Agents; Brain; Brain Neoplasms; Cannabinoid Receptor Mod

2007
Ciglitazone induces caspase-independent apoptosis through down-regulation of XIAP and survivin in human glioma cells.
    Neurochemical research, 2008, Volume: 33, Issue:3

    Topics: Annexin A5; Apoptosis; Apoptosis Inducing Factor; Blotting, Western; Brain Neoplasms; Caspases; Cell

2008