cifenline has been researched along with Kidney Failure, Chronic in 8 studies
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test the hypothesis that renal failure alters the disposition of cibenzoline in humans, an absolute bioavailability and elimination kinetic study was performed." | 2.67 | Bioavailability and kinetics of cibenzoline in patients with normal and impaired renal function. ( Aogaichi, K; Aronoff, G; Barbalas, M; Brazzell, R; Brier, M; Massarella, J; Mayer, ML; Sloan, R, 1991) |
| " The pharmacokinetic parameters observed in the healthy volunteers were similar to those reported previously." | 1.27 | Effect of renal impairment on the pharmacokinetics of cibenzoline. ( Aogaichi, K; Chow, MS; Di Persio, D; Khoo, KC; Kluger, J; Massarella, JW; Smith, M, 1988) |
| " Plasma elimination half-life was prolonged, with values ranging from 7:4 to 23." | 1.27 | Pharmacokinetics of cibenzoline in patients with renal impairment. ( Aubert, P; Baglin, A; Canal, M; Flouvat, B; Guedon, J; Prinseau, J, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takahashi, M | 1 |
| Echizen, H | 1 |
| Takahashi, K | 1 |
| Shimada, S | 1 |
| Aoyama, N | 1 |
| Izumi, T | 1 |
| Ozasa, Y | 1 |
| Takamura, S | 1 |
| Seishi, I | 1 |
| Kitada, H | 1 |
| Uekihara, S | 1 |
| Hayano, S | 1 |
| Kasuga, A | 1 |
| Maruyama, H | 1 |
| Sato, T | 1 |
| Nogawa, S | 1 |
| Mitamura, H | 1 |
| Saruta, T | 1 |
| Wakutani, Y | 1 |
| Matsushima, E | 1 |
| Son, A | 1 |
| Shimizu, Y | 1 |
| Goto, Y | 1 |
| Ishida, H | 1 |
| Honda, T | 2 |
| Soejima, H | 1 |
| Aronoff, G | 1 |
| Brier, M | 1 |
| Mayer, ML | 1 |
| Barbalas, M | 1 |
| Aogaichi, K | 2 |
| Sloan, R | 1 |
| Brazzell, R | 1 |
| Massarella, J | 1 |
| Massarella, JW | 1 |
| Khoo, KC | 1 |
| Di Persio, D | 1 |
| Smith, M | 1 |
| Kluger, J | 1 |
| Chow, MS | 1 |
| Canal, M | 1 |
| Flouvat, B | 1 |
| Aubert, P | 1 |
| Guedon, J | 1 |
| Prinseau, J | 1 |
| Baglin, A | 1 |
2 trials available for cifenline and Kidney Failure, Chronic
| Article | Year |
|---|---|
Long-term low-dose cibenzoline in patients with chronic renal failure undergoing hemodialysis.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Dose-Respon | 2000 |
Bioavailability and kinetics of cibenzoline in patients with normal and impaired renal function.
Topics: Administration, Oral; Adult; Biological Availability; Half-Life; Humans; Imidazoles; Infusions, Intr | 1991 |
6 other studies available for cifenline and Kidney Failure, Chronic
| Article | Year |
|---|---|
Extremely prolonged elimination of cibenzoline at toxic plasma concentrations in patients with renal impairments.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Chromatography, High P | 2002 |
[A case of acute cibenzoline intoxication in a hemodialysis patient].
Topics: Acute Disease; Aged; Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Humans; Imida | 2003 |
Myasthenia-like syndrome induced by overdosage of cibenzoline.
Topics: Aged; Anti-Arrhythmia Agents; Aortic Aneurysm; Aortic Dissection; Atrial Fibrillation; Blepharoptosi | 1996 |
Myasthenialike syndrome due to adverse effects of cibenzoline in a patient with chronic renal failure.
Topics: Angina Pectoris; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electric Stimulation; Heart Ventricle | 1998 |
Effect of renal impairment on the pharmacokinetics of cibenzoline.
Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Female; Humans; Imidazoles; Kidney Failur | 1988 |
Pharmacokinetics of cibenzoline in patients with renal impairment.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Creatinine; Female; Half-Life; Humans; Im | 1985 |