Compounds > cidofovir anhydrous
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cidofovir anhydrous and Herpes Simplex

cidofovir anhydrous has been researched along with Herpes Simplex in 57 studies

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's19 (33.33)18.2507
2000's18 (31.58)29.6817
2010's14 (24.56)24.3611
2020's6 (10.53)2.80

Authors

AuthorsStudies
Andrei, G; Balzarini, J; Hocková, D; Holý, A; Snoeck, R1
Andrei, G; De Jonghe, S; Herdewijn, P; Lescrinier, E; Plebanek, E; Snoeck, R1
Abdel-Moty, SG; Andrei, G; Hayallah, AM; Mohammed, AF; Simons, C; Snoeck, R1
Bouscarat, F; Boutolleau, D; Bucau, M; Burrel, S; Fidouh, N; Ghosn, J; Hachon, L; Joly, V; Khellaf, L; Lariven, S; Le Pluart, D; Thy, M1
Andrei, G; Gillemot, S; Reynders, M; Schalkwijk, HH; Selleslag, D; Snoeck, R1
Bertin, C; Blaizot, R; Couppié, P; Jumpertz, M1
Heidenreich, D; Hofmann, WK; Jawhar, M; Klein, SA; Kreil, S; Mueller, N; Nolte, F1
Amaral, BP; Cargnelutti, JF; Feio, LM; Flores, E; Merchioratto, I; Mortari, APG; Nogueira, CW; Weiblen, R1
Baukmann, S; Brunnemann, AK; Bühler, S; Fickenscher, H; Krumbholz, A; Rose, R; Sauerbrei, A; Zell, R1
Dhillon, VK; Kumar, PN; Mathur, A; Yang, CQ1
Agut, H; Boutolleau, D; Burrel, S; Caumes, E; Epelboin, L; Katlama, C; Regnier, S; Seang, S; Valantin, MA; Voujon, D1
Alaibac, M; Peserico, A; Piaserico, S; Sandini, E1
Chemaly, RF; Hosing, C; Lahoti, A; Saunders, IM; Trevino, C; Westmoreland, M1
Epstein, JB; Gharapetian, S; Lill, M; Rejali, AR; Tzachanis, D; Zabner, R1
Edelmann, A; Hofmann, J; Kühl, JS; Sauerbrei, A; Voigt, S1
Barshak, MB; Durand, ML; Foster, CS; Kim, IK; Mali, JO; Scott, NL; Stryjewski, TP; Tobin, EH; Young, LH1
Cieśluk, B; Dzieciatkowski, T; Majewska, A; Łuczak, M1
Bernardin, R; Castelo-Soccio, L; Goldstein, SA; Kovarik, C; Stern, J1
Ellis, RM; Hood, AF; Mohr, MR; Oldfield, EC1
Bohn, K; Hamprecht, K; Heim, A; Hoffmann, D; Hofmann, J; Jahn, G; Sauerbrei, A; Schnitzler, P; Weissbrich, B; Wutzler, P; Zell, R1
Armistead, P; Dean, A; Khan, T; Muluneh, B1
Snoeck, R1
Morfin, F; Thouvenot, D1
Afouna, MI; Fincher, TK; Reddy, IK; Zaghloul, AA1
Blauvelt, A; Sanchez, S; Toro, JR; Turiansky, G1
Chilukuri, S; Rosen, T1
Hirschel, B; Pechère, M; Piguet, V; Saurat, JH; Schiffer, V; Toutous-Trellu, L1
Aoki, K; Eto, T; Gondo, H; Harada, M; Henzan, H; Kato, K; Miyamoto, T; Nagafuji, K; Nagatoshi, Y; Obama, K; Ohba, T1
Bessesen, M; Krause, PR; Madinger, N; Patel, A; Weinberg, A; Wyles, DL1
Aldern, KA; Beadle, JR; Hartline, CB; Hostetler, KY; Keith, KA; Kern, ER; Ruiz, JC1
Andrei, G; De Clercq, E; Fiten, P; Gordts, B; Goubau, P; Opdenakker, G; Selleslag, D; Snoeck, R; van Landuyt, H1
Andrei, G; De Clercq, E; Fiten, P; Froeyen, M; Opdenakker, G; Snoeck, R1
Assil, KK; Bergeron-Lynn, G; Besen, G; De Clercq, E; Flores-Aguilar, M; Gangan, P; Kupperman, BD; Munguia, D; Pursley, M; Vuong, C1
Andrei, G; Balzarini, J; Clumeck, N; De Clercq, E; Gérard, M; Hedderman, A; Sadzot-Delvaux, C; Silverman, A; Snoeck, R; Tricot, G1
Davidson, JM; Drew, WL; Fisher, PE; Glutzer, E; Jaffe, HS; Lalezari, JP; Miner, D; Owen, WF; Safrin, S1
Bergeron-Lynn, G; Chandler, B; De Clercq, E; Flores-Aguilar, M; Freeman, WR; Huang, JS; Munguia, D; Vuong, C; Wiley, CA1
Andrei, G; Clumeck, N; De Clercq, E; Gerard, M; Sadzot-Delvaux, C; Snoeck, R; Tricot, G1
Assil, KK; Bergeron-Lynn, G; Besen, G; Connor, JD; De Clercq, E; Freeman, WR; Kuppermann, BD; Munguia, D; Pursley, M; Vuong, C; Wiley, CA1
Boggs, J; Cheung, T; Corey, L; Drew, WL; Feinberg, J; Gathe, J; Jaffe, HS; Kessler, H; Kramer, F; Lalezari, J; Lee, S; McGuire, B; Safrin, S; Schacker, T1
Luks-Golger, DB; Martinez, CM1
Levine, JF; LoPresti, AE; Mendel, DB; Munk, GB; Tai, CY1
Engler, RJ; Katial, RK; Myers, KW1
Don, PC; Kaufmann, M; Lateef, F; Weinberg, JM; White, SM1
Afouna, MI; DeClercq, E; El-Shattawy, HH; Ghanem, AH; Higuchi, WI; Kern, ER; Mehta, SC1
Aymard, M; Chen, Y; Devergie, A; Espérou, H; Garderet, L; Garrait, V; Gluckman, E; Hocqueloux, L; Leleu, G; Molina, JM; Morfin, F; Morinet, F; Ribaud, P; Rocha, V; Scieux, C; Sélimi, F; Socié, G; Thouvenot, D1
Blot, N; Dehesdin, D; Janvresse, C; Schneider, P; Tron, P; Vannier, JP; Young, P1
Bordigoni, P; Carret, AS; Corsaro, D; Dauendorffer, JN; Edert, D; Le Faou, A; Venard, V1
Bryant, P; Carapetis, J; Curtis, N; Sasadeusz, J; Waters, K1
Ait Arkoub, Z; Arnulf, B; Chebbi, F; Fillet, AM; Lefrere, F; Varet, B1
Geusau, A; Kopp, T; Rieger, A; Stingl, G1
Hitchcock, MJ; Martin, JC1
De Castro, LM; De Clercq, E; Gangemi, JD; Ghaffar, A; Kern, ER; Mayer, EP; Vogt, PE1
Datema, R; Yang, H1
De Clercq, E; Holý, A1

Reviews

6 review(s) available for cidofovir anhydrous and Herpes Simplex

ArticleYear
Cutaneous viral infections in organ transplant patients.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2014, Volume: 149, Issue:4

    Topics: Acitretin; Administration, Cutaneous; Aminoquinolines; Antiviral Agents; Cidofovir; Cytosine; Dermatologic Agents; Hair Diseases; Herpes Simplex; Herpes Zoster; Humans; Ichthyosis; Imiquimod; Immunocompromised Host; Immunosuppressive Agents; Incidence; Italy; Molluscum Contagiosum; Organ Transplantation; Organophosphonates; Skin Diseases, Viral; Transplant Recipients; Warts

2014
[Perspectives for the treatment and prevention of herpes simplex infections].
    Annales de dermatologie et de venereologie, 2002, Volume: 129, Issue:4 Pt 2

    Topics: 2-Aminopurine; Acyclovir; Aminoquinolines; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Famciclovir; Herpes Simplex; Herpes Simplex Virus Vaccines; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Imiquimod; Interferon Inducers; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine

2002
Herpes simplex virus resistance to antiviral drugs.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2003, Volume: 26, Issue:1

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Enzyme Inhibitors; Exodeoxyribonucleases; Foscarnet; Herpes Simplex; Humans; Immunocompromised Host; Mutation; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Thymidine Kinase; Viral Proteins; Virus Replication

2003
Topical cidofovir for the treatment of dermatologic conditions: verruca, condyloma, intraepithelial neoplasia, herpes simplex and its potential use in smallpox.
    Dermatologic clinics, 2003, Volume: 21, Issue:2

    Topics: Administration, Cutaneous; Administration, Topical; Antiviral Agents; Carcinoma in Situ; Carcinoma, Squamous Cell; Cidofovir; Condylomata Acuminata; Cytosine; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Skin Diseases, Infectious; Skin Neoplasms; Smallpox; Warts

2003
Management of acyclovir-resistant herpes simplex virus.
    Dermatologic clinics, 2003, Volume: 21, Issue:2

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Foscarnet; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Stomatitis, Herpetic; Trifluridine; Vidarabine

2003
Cidofovir use in acyclovir-resistant herpes infection.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:12

    Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Simplexvirus

1997

Trials

5 trial(s) available for cidofovir anhydrous and Herpes Simplex

ArticleYear
Diphenyl diselenide and cidofovir present anti-viral activity against Bovine Alphaherpesvirus 2 in vitro and in a sheep model.
    Research in veterinary science, 2021, Volume: 134

    Topics: Animals; Antiviral Agents; Benzene Derivatives; Cidofovir; Female; Herpes Simplex; Herpesvirus 2, Bovine; Mammary Glands, Animal; Organoselenium Compounds; Sheep; Sheep Diseases; Virus Shedding

2021
[Treatment of cutaneous human papilloma virus, poxvirus and herpes simplex virus infections with topical cidofovir in HIV positive patients].
    Annales de dermatologie et de venereologie, 2004, Volume: 131, Issue:5

    Topics: Administration, Topical; Adult; Antiviral Agents; Cidofovir; Cytosine; Female; Herpes Simplex; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Poxviridae Infections; Skin Diseases, Viral

2004
Cidofovir for treating adenoviral hemorrhagic cystitis in hematopoietic stem cell transplant recipients.
    Bone marrow transplantation, 2004, Volume: 34, Issue:10

    Topics: Adenoviridae; Adenoviridae Infections; Adolescent; Adult; Antiviral Agents; Child; Cidofovir; Cystitis; Cytomegalovirus Infections; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Humans; Male; Middle Aged; Opportunistic Infections; Organophosphonates; Treatment Outcome

2004
A randomized, double-blind, placebo-controlled trial of cidofovir gel for the treatment of acyclovir-unresponsive mucocutaneous herpes simplex virus infection in patients with AIDS.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Animals; Antiviral Agents; Cells, Cultured; Chlorocebus aethiops; Cidofovir; Cytosine; Double-Blind Method; Drug Resistance, Microbial; Female; Foscarnet; Gels; Herpes Simplex; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mouth Mucosa; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Vero Cells

1997
NDA filed to treat refractory herpes.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:2

    Topics: Administration, Topical; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Approval; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Randomized Controlled Trials as Topic; Recurrence; United States; United States Food and Drug Administration

1997

Other Studies

46 other study(ies) available for cidofovir anhydrous and Herpes Simplex

ArticleYear
Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: efficient synthesis and antiviral activity.
    Bioorganic & medicinal chemistry, 2011, Aug-01, Volume: 19, Issue:15

    Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Herpes Simplex; HIV; HIV Infections; Humans; Mice; Nucleosides; Organophosphonates; Simplexvirus; Structure-Activity Relationship; Vaccinia; Vaccinia virus; Virus Diseases; Viruses

2011
Emimycin and its nucleoside derivatives: Synthesis and antiviral activity.
    European journal of medicinal chemistry, 2018, Jan-20, Volume: 144

    Topics: Antiviral Agents; Cell Line; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 3, Human; Humans; Nucleosides; Pyrazines; Varicella Zoster Virus Infection; Virus Replication

2018
Synthesis and anti-HSV activity of tricyclic penciclovir and hydroxybutylguanine derivatives.
    Bioorganic & medicinal chemistry, 2019, 03-15, Volume: 27, Issue:6

    Topics: Acyclovir; Antiviral Agents; Guanine; Herpes Genitalis; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Models, Molecular

2019
Novel mutations in antiviral multiresistant HSV-2 genital lesion: A case report.
    Journal of medical virology, 2022, Volume: 94, Issue:12

    Topics: Acyclovir; Antiviral Agents; Cidofovir; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Genitalia; Herpes Simplex; Herpesvirus 2, Human; Humans; Imiquimod; Mutation; Obesity; Thymidine Kinase; Valacyclovir

2022
Heterogeneity and viral replication fitness of HSV-1 clinical isolates with mutations in the thymidine kinase and DNA polymerase.
    The Journal of antimicrobial chemotherapy, 2022, 10-28, Volume: 77, Issue:11

    Topics: Acyclovir; Antiviral Agents; Cidofovir; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Herpes Simplex; Herpesvirus 1, Human; Humans; Mutation; Thymidine Kinase; Virus Replication

2022
Intravenous cidofovir for pseudotumoral genital herpes simplex virus infection in two persons living with human immunodeficiency virus (HIV).
    International journal of dermatology, 2023, Volume: 62, Issue:4

    Topics: Cidofovir; Genitalia; Herpes Genitalis; Herpes Simplex; Herpesvirus 2, Human; HIV; HIV Infections; Humans

2023
Topical Treatment of Acyclovir-Resistant Herpes Simplex Virus Stomatitis after Allogeneic Hematopoietic Cell Transplantation.
    Oncology research and treatment, 2020, Volume: 43, Issue:12

    Topics: Acyclovir; Administration, Topical; Adult; Aged; Antiviral Agents; Cidofovir; Drug Resistance, Viral; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesvirus 1, Human; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Stomatitis; Treatment Outcome

2020
Antiviral susceptibility of recombinant Herpes simplex virus 1 strains with specific polymerase amino acid changes.
    Antiviral research, 2021, Volume: 195

    Topics: Acyclovir; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Guanine; Herpes Simplex; Herpesvirus 1, Human; Humans; Immunocompromised Host; Microbial Sensitivity Tests; Thymidine Kinase; Vero Cells

2021
Intralesional Cidofovir for Treatment of Acyclovir-Resistant Laryngeal Herpes Manifesting as Supraglottic Mass.
    The Annals of otology, rhinology, and laryngology, 2019, Volume: 128, Issue:3

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Herpes Simplex; Humans; Injections, Intralesional; Laryngitis; Male; Middle Aged

2019
Long-term follow-up of HIV-infected patients once diagnosed with acyclovir-resistant herpes simplex virus infection.
    International journal of STD & AIDS, 2014, Volume: 25, Issue:9

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Follow-Up Studies; Foscarnet; Herpes Simplex; HIV Infections; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates; Retrospective Studies; Skin Diseases, Viral; Skin Ulcer; Socioeconomic Factors; Thymidine Kinase; Treatment Outcome

2014
Topical cidofovir-induced acute kidney injury in two severely immunocompromised patients with refractory multidrug-resistant herpes simplex virus infections.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2016, Volume: 22, Issue:2

    Topics: Acute Kidney Injury; Administration, Topical; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Multiple, Viral; Herpes Simplex; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates

2016
Complex management of resistant oral herpes simplex virus infection following hematopoietic stem cell transplantation: potential role of topical cidofovir.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016, Volume: 24, Issue:8

    Topics: Administration, Topical; Aged; Antiviral Agents; Cidofovir; Cytosine; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Humans; Male; Organophosphonates; Transplantation Conditioning

2016
Brincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation.
    Transplant infectious disease : an official journal of the Transplantation Society, 2016, Volume: 18, Issue:5

    Topics: Acyclovir; Adenoviridae; Adenovirus Infections, Human; Antibiotic Prophylaxis; Antiviral Agents; Child, Preschool; Cidofovir; Cytosine; DNA, Viral; Drug Resistance, Viral; Epstein-Barr Virus Infections; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpes Zoster; Herpesvirus 1, Human; Herpesvirus 3, Human; Herpesvirus 4, Human; Humans; Immunocompromised Host; Meningoencephalitis; Mucositis; Myelodysplastic Syndromes; Organophosphonates; Rituximab; Viral Load

2016
Treatment of Refractory Acute Retinal Necrosis with Intravenous Foscarnet or Cidofovir.
    Ocular immunology and inflammation, 2018, Volume: 26, Issue:2

    Topics: Aged; Aged, 80 and over; Antiviral Agents; Cidofovir; Cytosine; Eye Infections, Viral; Foscarnet; Herpes Simplex; Herpes Zoster Ophthalmicus; Herpesvirus 3, Human; Humans; Infusions, Intravenous; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Retinal Necrosis Syndrome, Acute; Retrospective Studies; Simplexvirus; Vitreous Body

2018
[In vitro acyclovir and cidofovir susceptibilities of human herpesvirus type 1 clinical isolates].
    Medycyna doswiadczalna i mikrobiologia, 2008, Volume: 60, Issue:2

    Topics: Acyclovir; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Herpes Simplex; Herpesvirus 1, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Vero Cells

2008
Successful treatment of acyclovir-resistant herpes simplex virus with intralesional cidofovir.
    Archives of dermatology, 2010, Volume: 146, Issue:2

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Facial Dermatoses; Herpes Simplex; Humans; Injections, Intralesional; Male; Organophosphonates

2010
Recalcitrant herpetic scrotal ulcer as a manifestation of immune reconstitution inflammatory syndrome.
    Journal of the American Academy of Dermatology, 2011, Volume: 65, Issue:2

    Topics: Administration, Topical; Adult; Antiretroviral Therapy, Highly Active; Antiviral Agents; Biopsy, Needle; Cidofovir; Cytosine; Diagnosis, Differential; Follow-Up Studies; Herpes Simplex; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Immunohistochemistry; Male; Organophosphonates; Scrotum; Severity of Illness Index; Skin Ulcer; Treatment Outcome; Wound Healing

2011
Novel resistance-associated mutations of thymidine kinase and DNA polymerase genes of herpes simplex virus type 1 and type 2.
    Antiviral therapy, 2011, Volume: 16, Issue:8

    Topics: Acyclovir; Adolescent; Adult; Aged; Antiviral Agents; Bromodeoxyuridine; Child; Child, Preschool; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Female; Foscarnet; Genotype; Guanine; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Infant; Male; Middle Aged; Mutation; Organophosphonates; Sequence Analysis, DNA; Thymidine Kinase; Viral Proteins

2011
Successful clearance of cutaneous acyclovir-resistant, foscarnet-refractory herpes virus lesions with topical cidofovir in an allogeneic hematopoietic stem cell transplant patient.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2013, Volume: 19, Issue:2

    Topics: Acyclovir; Administration, Topical; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Foscarnet; Gels; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesvirus 1, Human; Humans; Organophosphonates; Real-Time Polymerase Chain Reaction; Transplantation, Homologous; Treatment Outcome

2013
Effect of Azone upon the in vivo antiviral efficacy of cidofovir or acyclovir topical formulations in treatment/prevention of cutaneous HSV-1 infections and its correlation with skin target site free drug concentration in hairless mice.
    International journal of pharmaceutics, 2003, Mar-06, Volume: 253, Issue:1-2

    Topics: Acyclovir; Adjuvants, Pharmaceutic; Administration, Topical; Animals; Antiviral Agents; Azepines; Cidofovir; Cytosine; Drug Administration Schedule; Female; Herpes Simplex; Herpesvirus 1, Human; Mice; Mice, Hairless; Organophosphonates; Organophosphorus Compounds; Permeability; Skin Absorption

2003
Development of herpes simplex virus disease in patients who are receiving cidofovir.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Sep-01, Volume: 41, Issue:5

    Topics: Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Herpes Simplex; Humans; Male; Organophosphonates; Simplexvirus

2005
Synthesis and antiviral evaluation of alkoxyalkyl-phosphate conjugates of cidofovir and adefovir.
    Antiviral research, 2007, Volume: 75, Issue:1

    Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cowpox; Cytomegalovirus Infections; Cytosine; Herpes Simplex; HIV-1; Humans; In Vitro Techniques; Molecular Structure; Organophosphonates; Sensitivity and Specificity; Vaccinia

2007
Dual infection with polyomavirus BK and acyclovir-resistant herpes simplex virus successfully treated with cidofovir in a bone marrow transplant recipient.
    Transplant infectious disease : an official journal of the Transplantation Society, 2007, Volume: 9, Issue:2

    Topics: Acyclovir; Adolescent; Antiviral Agents; BK Virus; Bone Marrow Transplantation; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Herpes Simplex; Herpesvirus 1, Human; Humans; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections

2007
DNA polymerase mutations in drug-resistant herpes simplex virus mutants determine in vivo neurovirulence and drug-enzyme interactions.
    Antiviral therapy, 2007, Volume: 12, Issue:5

    Topics: Adenine; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Enzyme Inhibitors; Exodeoxyribonucleases; Foscarnet; Genotype; Herpes Simplex; Herpesvirus 1, Human; Humans; Mice; Models, Molecular; Mutation; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Phenotype; Protein Binding; Protein Conformation; Vero Cells; Viral Proteins; Virulence

2007
Long-term therapy for herpes retinitis in an animal model with high-concentrated liposome-encapsulated HPMPC.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1995, Volume: 113, Issue:5

    Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Electroretinography; Eye Infections, Viral; Fundus Oculi; Herpes Simplex; Liposomes; Longitudinal Studies; Organophosphonates; Organophosphorus Compounds; Rabbits; Retinitis

1995
Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC).
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18, Issue:4

    Topics: Acyclovir; Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; DNA Restriction Enzymes; DNA, Viral; Drug Resistance, Microbial; Foscarnet; Herpes Genitalis; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Opportunistic Infections; Organophosphonates; Organophosphorus Compounds; Skin Diseases, Viral; Thymidine Kinase

1994
Treatment with intravenous (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]-cytosine of acyclovir-resistant mucocutaneous infection with herpes simplex virus in a patient with AIDS.
    The Journal of infectious diseases, 1994, Volume: 170, Issue:3

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Herpes Simplex; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Organophosphonates; Organophosphorus Compounds; Simplexvirus

1994
Long-acting therapy of viral retinitis with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine.
    The Journal of infectious diseases, 1994, Volume: 169, Issue:3

    Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Ganciclovir; Herpes Simplex; Herpesvirus 1, Human; Organophosphonates; Organophosphorus Compounds; Rabbits; Retinitis; Time Factors

1994
A new topical treatment for resistant herpes simplex infections.
    The New England journal of medicine, 1993, Sep-23, Volume: 329, Issue:13

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance; Herpes Simplex; Humans; Immunocompromised Host; Organophosphonates; Organophosphorus Compounds; Simplexvirus

1993
Liposome-encapsulated (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine for long-acting therapy of viral retinitis.
    The Journal of infectious diseases, 1996, Volume: 173, Issue:1

    Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Drug Carriers; Eye Infections, Viral; Herpes Simplex; Herpesvirus 1, Human; Injections; Liposomes; Organophosphonates; Organophosphorus Compounds; Rabbits; Retina; Retinitis; Vitreous Body

1996
Successful treatment of an acyclovir- and foscarnet-resistant herpes simplex virus type 1 lesion with intravenous cidofovir.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 26, Issue:2

    Topics: Acyclovir; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Foscarnet; Herpes Simplex; Herpesvirus 1, Human; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Organophosphonates; Organophosphorus Compounds

1998
Probenecid hypersensitivity in AIDS: a case report.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1998, Volume: 80, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Cidofovir; Cytosine; Drug Hypersensitivity; Herpes Simplex; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid; Uricosuric Agents

1998
Treatment of acyclovir-resistant, foscarnet-unresponsive HSV infection with topical cidofovir in a child with AIDS.
    Archives of dermatology, 1998, Volume: 134, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Anti-HIV Agents; Child, Preschool; Cidofovir; Cytosine; Drug Resistance, Microbial; Facial Dermatoses; Foscarnet; Herpes Simplex; Humans; Male; Organophosphonates; Organophosphorus Compounds; Treatment Failure

1998
Influence of the treatment protocol upon the in vivo efficacy of cidofovir (HPMPC) and of acyclovir (ACV) formulations in topical treatment of cutaneous HSV-1 infection in hairless mice.
    Journal of pharmaceutical sciences, 1999, Volume: 88, Issue:5

    Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; Female; Herpes Simplex; Mice; Mice, Hairless; Organophosphonates; Organophosphorus Compounds; Skin Diseases, Viral

1999
Resistant herpes simplex virus type 1 infection: an emerging concern after allogeneic stem cell transplantation.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 31, Issue:4

    Topics: Acyclovir; Adolescent; Adult; Antiviral Agents; Child; Cidofovir; Cytosine; Drug Resistance, Microbial; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesvirus 1, Human; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Transplantation, Homologous

2000
Treatment of an acyclovir and foscarnet-resistant herpes simplex virus infection with cidofovir in a child after an unrelated bone marrow transplant.
    Bone marrow transplantation, 2000, Volume: 26, Issue:8

    Topics: Acyclovir; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytosine; Drug Resistance; Female; Foscarnet; Herpes Simplex; Humans; Infant; Organophosphonates; Organophosphorus Compounds

2000
Gilead announces phase I/II data insufficient for marketing clearance of FORVADE topical gel to treat refractory herpes in patients with AIDS.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:4

    Topics: Administration, Topical; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytosine; Herpes Simplex; Humans; Investigational New Drug Application; Organophosphonates; Organophosphorus Compounds; United States; United States Food and Drug Administration

1997
Acyclovir-resistant herpes: expanded access available for cidofovir gel (Forvade).
    AIDS treatment news, 1997, Feb-07, Issue:No 264

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Approval; Gels; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds

1997
Infection due to acyclovir resistant herpes simplex virus in patients undergoing allogeneic hematopoietic stem cell transplantation.
    Pathologie-biologie, 2001, Volume: 49, Issue:7

    Topics: Acute Disease; Acyclovir; Adolescent; Amino Acid Substitution; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Codon; Cytosine; DNA Mutational Analysis; Drug Resistance, Viral; Female; Foscarnet; Graft vs Host Disease; Herpes Simplex; Humans; Immunocompromised Host; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Male; Mutation, Missense; Organophosphonates; Organophosphorus Compounds; Point Mutation; Salvage Therapy; Simplexvirus; Thymidine Kinase; Transplantation, Homologous; Valacyclovir; Valine; Viral Proteins; Virus Activation

2001
Successful treatment of foscarnet-resistant herpes simplex stomatitis with intravenous cidofovir in a child.
    The Pediatric infectious disease journal, 2001, Volume: 20, Issue:11

    Topics: Acyclovir; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Cytosine; Drug Resistance, Multiple, Viral; Female; Foscarnet; Herpes Simplex; Herpesvirus 1, Human; Humans; Immunocompromised Host; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Stomatitis

2001
Multiple herpes simplex virus infections with various resistance patterns in a matched unrelated donor transplant recipient.
    Bone marrow transplantation, 2001, Volume: 28, Issue:8

    Topics: Acyclovir; Antineoplastic Agents, Alkylating; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Combined Modality Therapy; Cyclosporine; Cytarabine; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Fatal Outcome; Foscarnet; Graft vs Host Disease; Herpes Genitalis; Herpes Simplex; Humans; Hydroxyurea; Immunocompromised Host; Immunosuppressive Agents; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methotrexate; Middle Aged; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Transplantation Conditioning; Whole-Body Irradiation

2001
Successful treatment of an aciclovir-resistant herpes simplex type 2 infection with cidofovir in an AIDS patient.
    The British journal of dermatology, 2002, Volume: 147, Issue:1

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Fissure in Ano; Herpes Simplex; Herpesvirus 2, Human; Humans; Organophosphonates; Organophosphorus Compounds

2002
Phosphonomethylether compounds as antiviral agents.
    Transplantation proceedings, 1991, Volume: 23, Issue:3 Suppl 3

    Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Haplorhini; Herpes Simplex; Mice; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Structure-Activity Relationship

1991
Phosphonylmethoxyalkyl purine and pyrimidine derivatives for treatment of opportunistic cytomegalovirus and herpes simplex virus infections in murine AIDS.
    Antiviral research, 1991, Volume: 16, Issue:1

    Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Herpes Simplex; Immune Tolerance; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Opportunistic Infections; Organophosphonates; Organophosphorus Compounds

1991
Prolonged and potent therapeutic and prophylactic effects of (S)-1-[(3-hydroxy-2-phosphonylmethoxy)propyl]cytosine against herpes simplex virus type 2 infections in mice.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:8

    Topics: Animals; Antiviral Agents; Brain Stem; Cidofovir; Cytosine; Drug Administration Schedule; Encephalitis; Female; Ganciclovir; Herpes Simplex; Mice; Organophosphonates; Organophosphorus Compounds; Premedication

1991
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine in various models of herpes simplex virus infection in mice.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:4

    Topics: Acyclovir; Animals; Antiviral Agents; Brain Diseases; Cidofovir; Cytosine; Herpes Simplex; Mice; Mice, Hairless; Mice, Nude; Organophosphonates; Organophosphorus Compounds; Peritoneal Cavity; Skin Diseases, Infectious

1991