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cidofovir anhydrous and Cytomegalovirus

cidofovir anhydrous has been researched along with Cytomegalovirus in 155 studies

*Cytomegalovirus: A genus of the family HERPESVIRIDAE, subfamily BETAHERPESVIRINAE, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions. Infection with Cytomegalovirus is also seen as an opportunistic infection in AIDS. [MeSH]

Research

Studies (155)

TimeframeStudies, this research(%)All Research%
pre-19903 (1.94)18.7374
1990's49 (31.61)18.2507
2000's60 (38.71)29.6817
2010's34 (21.94)24.3611
2020's9 (5.81)2.80

Authors

AuthorsStudies
Bronson, JJ; Ghazzouli, I; Hitchcock, MJ; Martin, JC; Webb, RR1
Alexander, P; Krishnamurthy, VV; Prisbe, EJ1
Bédard, J; Chan, L; Nguyen-Ba, P; Quimpère, M; Turcotte, N; Yuen, L1
Andrei, G; De Clercq, E; Froeyen, M; Hendrix, C; Herdewijn, P; Snoeck, R; Wang, J1
Andrei, G; Balzarini, J; Castro, A; De Clercq, E; Gil, C; Martinez, A; Otero, J; Perez, C; Prieto, C; Snoeck, R1
De Clercq, E; Garuti, L; Roberti, M1
Andrei, G; Balzarini, J; De Clercq, E; McGuigan, C; Pathirana, RN; Snoeck, R1
Andrei, G; Balzarini, J; De Clercq, E; García-López, MT; Gerona-Navarro, G; González-Muñiz, R; Pérez de Vega, MJ; Snoeck, R2
Andrei, G; Balzarini, J; Barbarić, M; Cetina, M; De Clercq, E; Frković, D; Kralj, M; Mintas, M; Nagl, A; Opacić, N; Pavelić, K; Raić-Malić, S; Snoeck, R; Zorc, B1
Andrei, G; Balzarini, J; Barbarić, M; De Clercq, E; Grdisa, M; Hergold-Brundić, A; Mintas, M; Nagl, A; Pavelić, K; Pilepić, V; Snoeck, R; Ursić, S; Zorc, B1
Bédard, J; Chan, L; Drouin, M; Falardeau, G; Lachance, H; St-Pierre, A; Yannopoulos, CG1
De Clercq, E; Glapski, C; Guillerm, G; Muzard, M; Pilard, S1
Beadle, JR; Ciesla, SL; Hartline, C; Hostetler, KY; Keith, KA; Kern, ER; Wan, WB1
Adrian, J; Chen, X; Cushing, TD; DiMaio, H; Doughan, B; Flygare, J; Jaen, J; Liang, L; Mayorga, V; Mellon, H; Miao, S; Peterson, MG; Powers, JP; Spector, F; Stein, C; Wright, M; Xu, D; Ye, Q1
Chou, S; Rawlinson, WD; Scott, GM; Weinberg, A1
Adrian, J; Chen, X; Cushing, T; Dimaio, H; Jaen, J; Liang, L; Mayorga, V; Miao, S; Peterson, MG; Powers, JP; Spector, F; Stein, C; Wright, M; Xu, D; Ye, Q1
Chou, S; Li, S; Marousek, GI; Van Wechel, LC; Weinberg, A1
Andrei, G; De Clercq, E; Enguehard-Gueiffier, C; Gueiffier, A; Snoeck, R; Véron, JB1
Andrei, G; Balzarini, J; Camarasa, MJ; de Castro, S; Naesens, L; Peromingo, MT; Snoeck, R; Velázquez, S1
Allouchi, H; Andrei, G; De Clercq, E; Enguehard-Gueiffier, C; Gueiffier, A; Snoeck, R; Véron, JB1
Andrei, G; Balzarini, J; Camarasa, MJ; De Castro, S; García-Aparicio, C; Snoeck, R; Velázquez, S1
Kesel, AJ1
Andrei, G; Balzarini, J; Dračínský, M; Holý, A; Krečmerová, M; Snoeck, R; Tichý, T1
Borysko, K; Breitenbach, J; Drach, JC; Hilfinger, J; Kashemirov, BA; Kijek, P; Kim, JS; McKenna, CE; Mitchell, S; Peterson, LW1
Borysko, KZ; Breitenbach, JM; Collins, M; Drach, JC; Hilfinger, JM; Kashemirov, BA; Krylov, IS; McKenna, CE; Peterson, LW; Serpi, M; Zakharova, VM1
Drach, JC; Li, C; Prichard, MN; Quenelle, DC; Zemlicka, J1
Andrei, G; Babkov, DA; Balzarini, J; Chizhov, AO; Khandazhinskaya, AL; Novikov, MS; Ozerov, AA; Paramonova, MP; Seley-Radtke, KL; Snoeck, R1
Andrei, G; Kokosza, K; Piotrowska, DG; Schols, D; Snoeck, R1
Andrei, G; Kraljević Pavelić, S; Makuc, D; Martinović, T; Mintas, M; Pavelić, K; Plavec, J; Schols, D; Snoeck, R; Stipković Babić, M; Wittine, K1
Andrei, G; Babkov, DA; Chizhov, AO; Khandazhinskaya, AL; Novikov, MS; Seley-Radtke, KL; Snoeck, R1
Andrei, G; Buckheit, RW; De Jonghe, S; Groaz, E; Hartman, T; Herdewijn, P; Kalkeri, R; Luo, M; Ptak, RG; Schols, D; Snoeck, R1
Andrei, G; Balzarini, J; Dračínský, M; Krečmerová, M; Pomeisl, K; Snoeck, R1
Andrei, G; Hulpia, F; Liekens, S; Noppen, S; Schols, D; Snoeck, R; Van Calenbergh, S; Vervaeke, P1
Chou, S1
Fan, Z; Huang, F; Jiang, L; Liu, Q; Shi, P; Sun, J; Wang, Z; Xu, J; Xu, N; Xuan, L; Yang, Y; Yin, Z; Yu, G1
Cho, SY; Choi, SM; Jung, JY; Kim, HJ; Kim, M; Lee, DG; Nho, D; Oh, EJ1
Alain, S; Aranzamendi, M; Berengua, C; Bodro, M; Cofan, F; Cordero, E; Esteva, C; Fernández Avilés, F; Fernández Sabé, N; Hantz, S; Len, O; Linares, L; Marcos, MÁ; Martin-Davila, P; Moreno, A; Mosquera, MM; Navarro Gabriel, M; Pérez Jiménez, AB; Plault, N; Rodríguez, C; Rovira, M; Sánchez-Palomino, S; Santos Bravo, M; Suarez-Lledó, M; Vidal, E1
Kleiboeker, SB1
Bar-On, S; Haynes, RK; Lantsberg, D; Laskov, I; Oiknine-Djian, E; Panet, A; Wolf, DG1
Chiereghin, A; Contini, C; Felici, S; Gabrielli, L; La Corte, R; Lazzarotto, T; Maritati, M; Piccirilli, G; Turello, G1
Aguilar-Guisado, M; Berastegui-Cabrera, J; Marrugal-Lorenzo, JA; Merino, L; Pachón, J; Sánchez-Céspedes, J1
Alfares, M; Ambinder, RF; Arav-Boger, R; Avery, RK; Forman, MS; Jones, RJ; Lees, L; Mehta Steinke, SA; Ostrander, D; Shedeck, A; Shoham, S; Valsamakis, A1
Boivin, G; Piret, J2
Bruminhent, J; Rotjanapan, P; Watcharananan, SP1
Agrawal, N; Beltran, D; Echenique, IA; Najafian, N; Ramirez-Ruiz, L1
Grassi, G; Mazzaglia, A; Neri, G; Pennisi, R; Piperno, A; Pizzo, MM; Scala, A; Sciortino, MT; Sortino, G; Zagami, R; Zhu, Y1
Meesing, A; Razonable, RR1
DeVita, AV; Gentry, BG; Markovich, KC; O'Brien, MS; Selleseth, D; Sethna, P1
Hartline, CB; James, SH; Lanier, ER; Price, NB; Prichard, MN1
Fischer, L; Göhring, K; Hamprecht, K; Jahn, G; Laib Sampaio, K1
Bowlin, TL; Chou, S; Komazin-Meredith, G; Williams, JD1
Gregg, K; Hakki, M; Kaul, DR1
Chou, S; Ercolani, RJ; Lefterova, MI; Pinsky, BA; Sahoo, MK; Strasfeld, LM1
Fischer, L; Göhring, K; Hamprecht, K; Jahn, G; Sampaio, KL1
Chou, S; Ercolani, RJ; Lanier, ER1
Fischer, L; Göhring, K; Hamprecht, K; Hofmann, J; Imrich, E; Jahn, G; Sampaio, KL1
Krecmerova, M1
Andrei, G; Chen, X; Liu, NN; Schols, D; Snoeck, R; Wen, YN; Wu, QP; Xiang, YH; Zhang, QS; Zhang, ZF; Zhang, ZY1
Asano-Mori, Y; Chiba, S; Kako, S; Kanda, Y; Kurokawa, M; Motokura, T; Oshima, K; Shiraki, K; Watanabe, T1
Járay, J; Péter, A; Telkes, G; Varga, M1
Chou, S; Lurain, NS1
Kern, ER; Prichard, MN1
Bowlin, TL; Chou, S; Marousek, G1
Chavala, S; Miller, MB; Moss, HB; Say, E1
Carmichael, A; Goldsmith, PM; Husain, MM; Middleton, SJ; Zhang, H1
Aldern, KA; Beadle, JR; Harden, E; Hartline, C; Hostetler, KY; Kern, ER; Rodriguez, N1
Zaia, JA2
Bakker, HI; De Boer, FM; Harmsen, MC; Meijer, DK; Molema, G; van der Strate, BW1
Baldanti, F; Campanini, G; Comolli, G; Gerna, G; Lilleri, D; Ridolfo, AL; Rusconi, S1
Alain, S; Belloc, S; Brouet, JC; Ducancelle, A; Malphettes, M; Mazeron, MC; Petit, F; Sanson Le Pors, MJ; Scieux, C1
Clark, DA; Emery, VC; Fryer, JF; Griffiths, PD1
Baldanti, F; Gerna, G; Lurain, N1
Bidanset, DJ; Hartline, CB; Kern, ER; Rybak, RJ2
Beadle, JR; Bidanset, DJ; Hostetler, KY; Kern, ER; Wan, WB1
Beadle, JR; Collins, DJ; Hostetler, KY; Kern, ER; Quenelle, DC; Wan, WB1
Freitag, M; Herget, T; Kupfer, R; Marschall, M; Morbitzer, M; Stamminger, T1
Beadle, JR; Ciesla, SL; Hartline, C; Hostetler, KY; Kern, ER; Valiaeva, N; Wan, WB1
Morton, CJ; Ng, HL; Parker, MW; Rawlinson, WD; Scott, GM1
Beadle, JR; Daily, SL; Harden, EA; Hartline, CB; Hostetler, KY; Kern, ER; Kushner, NL; Prichard, MN; Wan, WB; Williams-Aziz, SL1
Boivin, G; Gilbert, C1
De Clercq, E1
Chou, S; Drew, WL; Marousek, GI; Miner, RC1
Abdelhalim, A; Almyroudis, NG; Battiwalla, M; Becker, J; Elefante, A; McCarthy, A; McCarthy, PL; Paplham, P; Segal, BH; Smith, P1
Eizuru, Y1
Bernstein, DI; Bravo, FJ; Cardin, RD1
Chou, S; Marousek, GI1
Beadle, JR; Collins, DJ; Hartline, CB; Hostetler, KY; Kern, ER; Pettway, LR; Quenelle, DC; Wan, WB1
Chou, S; Li, S; Marousek, G; Weinberg, A1
Chatterjee, S; Gangopadhyay, NN; Whitley, RJ1
Hamzeh, FM; Lee, FE; Lietman, PS; Moore, MR1
De Clercq, E; Neyts, J1
Bruggeman, CA; de Clercq, E; Havenith, M; Stals, FS; Zeytinoglu, A1
De Clercq, E; Neyts, J; Snoeck, R; Sobis, H; Vandeputte, M1
Cherrington, JM; Drew, WL; Hitchcock, MJ; Lalezari, JP; Miner, R1
Chen, MS; Huang, ES; Kim, C; Smith, JL; Xiong, X1
Flaherty, JF1
Bryson, HM; Lea, AP1
Andrei, G; De Clercq, E; Snoeck, R1
Bosmans, E; Bron, D; De Clereq, E; Delforge, A; Lagneaux, L; Schols, D; Snoeck, R; Stryckmans, P1
Chen, MS; Smith, JL; Xiong, X1
Kuppermann, BD1
Eizuru, Y; Harada, K; Ihara, S; Isashiki, Y; Minamishima, Y1
Cherrington, JM; Freeman, WR; Fuller, MD; Jiles, RE; Smith, IL; Spector, SA1
Chou, S; Drew, WL; Follansbee, SE; Guentzel, S; Lalezari, JP; Marousek, G; Miner, RC; Poscher, ME1
Pérez, JL1
Takahashi, K1
Ai, E; Freeman, WR; Mueller, AJ; Powell, HC; Rahhal, FM; Smith, IL; Spector, SA; Taskintuna, I1
Baldanti, F; Biron, KK; Gerna, G1
Freeman, WR; Karavellas, MP; Macdonald, JC; Morse, LS; Reed, JB; Torriani, FJ1
Cherrington, JM; Cihlar, T; Fuller, MD1
Cherrington, JM; Cihlar, T; Fuller, MD; Mulato, AS1
Aissa, N; Carquin, J; Dewilde, A; Freymuth, F; Houhou-Fidouh, N; Mazeron, MC; Scieux, C; Thouvenot, D1
Dunn, JP; Enger, C; Forman, M; Hubbard, L; Jabs, DA1
Cherrington, JM; Drew, WL; Fuller, MD; Lalezari, JP; Lamy, PD; Miner, R; Nuessle, S1
Avila, CP; Cheng, L; Freeman, WR; Keefe, KS; Macdonald, JC; Rao, NA1
Bedard, J; Bowlin, T; Chan, L; Drach, J; Huffman, J; Lis, M; May, S; Rando, R; Sidwell, R; Tryphonas, L1
Barbeau, D; Bedard, J; Bowlin, TL; May, S; Rando, RF; Yuen, L1
Buchanan, J; Davis, LJ1
Bowen, EF; Cherrington, JM; Emery, VC; Griffiths, PD; Johnson, MA; Lamy, PD1
Cherrington, J; Jaffe, HS; Safrin, S1
Botsis, C; Kyriakis, KP; Paparizos, VA; Papastamopoulos, V; Stavrianeas, NG; Zagoraios, Y1
Einsele, H; Hebart, H1
Biel, SS; Chen, S; Gelderblom, HR; Held, TK; Kurth, A; Nitsche, A; Siegert, W1
Chou, S; Drew, WL; Miner, RC1
Distler, A; Ketteler, M; Mertz, A; Offermann, G; Preuschof, L; Schäfer, H; Stöffler-Meilicke, M1
Boeckh, M; Chuang, EL; Corey, L; Crippa, F; Sale, G1
Bruggeman, CA; Bruning, JH; De Clercq, E; Lemström, K; Persoons, M; Stals, FS1
Bandt, D; Bornhäuser, M; Ehninger, G; Freiberg-Richter, J; Geissler, G; Helwig, A; Platzbecker, U; Plettig, R; Rethwilm, A; Schuler, U; Thiede, C1
Blanchet, KD1
Emery, VC1
Basara, N; Kiehl, MG1
Castagnola, E; Chierici, M; Cristina, E; Lanino, E; Miano, M; Morreale, G1
Alkan, S; Bhorade, SM; Garrity, ER; Husain, AN; McCabe, MA; Norwick, L; Sandesara, C; Vigneswaran, WT; Yeldandi, V1
Chakrabarti, S; Collingham, KE; Fegan, CD; Milligan, DW; Osman, H1
Chou, SW1
Bartolozzi, B; Bosi, A; Guidi, S; Orsi, A; Rossi Ferrini, P; Vannucchi, AM1
Andrei, G; Blaheta, RA; Cinatl, J; De Clercq, E; Doerr, HW; Kreuter, J; Michaelis, M; Neyts, J; Rabenau, HF; Snoeck, R; Vogel, JU1
Cinatl, J; Doerr, HW; Kreuter, J; Langer, K; Michaelis, M; Rabenau, H; Vogel, JU1
Holý, A; Otová, B; Votruba, I1
Kern, ER1
Hitchcock, MJ; Martin, JC1
Andrei, G; De Clercq, E; Neyts, J; Schols, D; Snoeck, R1
Balzarini, J; De Clercq, E; Neyts, J; Snoeck, R1
De Clercq, E; Himpens, B; Neyts, J; Schols, D; Snoeck, R1
Bruggeman, CA; de Clercq, E; Stals, FS1
Baba, M; De Clercq, E; Konno, K; Shigeta, S; Yokota, T1
Kim, CU; Luh, BY; Martin, JC1
Feng, JS; Fong, CK; Hsiung, GD; Li, SB; Lucia, HL; Yang, ZH1
Balzarini, J; Bron, D; De Clercq, E; Delforge, A; Lagneaux, L; Snoeck, R; Stryckmans, P; Van der Auwera, P1
Balzarini, J; De Clercq, E; Neyts, J; Schols, D; Snoeck, R1
De Clercq, E; Holy, A; Rosenberg, I; Sakuma, T; Snoeck, R1

Reviews

18 review(s) available for cidofovir anhydrous and Cytomegalovirus

ArticleYear
New Developments in the Management of Cytomegalovirus Infection After Transplantation.
    Drugs, 2018, Volume: 78, Issue:11

    Topics: Acetates; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Immunotherapy; Organ Transplantation; Quinazolines; Valganciclovir

2018
Antiviral drug resistance in herpesviruses other than cytomegalovirus.
    Reviews in medical virology, 2014, Volume: 24, Issue:3

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Viral; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Herpesvirus 6, Human; Humans; Immunocompromised Host; Organophosphonates

2014
Amino Acid Ester Prodrugs of Nucleoside and Nucleotide Antivirals.
    Mini reviews in medicinal chemistry, 2017, Volume: 17, Issue:10

    Topics: Adenine; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Herpesvirus 3, Human; Humans; Nucleosides; Nucleotides; Organophosphonates; Prodrugs

2017
[Gastrointestinal cytomegalovirus infections in organ transplant patients].
    Orvosi hetilap, 2008, Dec-21, Volume: 149, Issue:52

    Topics: Acyclovir; Antiviral Agents; Biopsy; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Endoscopy, Gastrointestinal; Foscarnet; Ganciclovir; Gastric Mucosa; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Immunocompromised Host; Immunoglobulins; Immunotherapy, Adoptive; Intestinal Mucosa; Organ Transplantation; Organophosphonates; Primary Prevention; Valganciclovir

2008
Antiviral drug resistance of human cytomegalovirus.
    Clinical microbiology reviews, 2010, Volume: 23, Issue:4

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genome, Viral; Humans; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Sequence Analysis, DNA

2010
The search for new therapies for human cytomegalovirus infections.
    Virus research, 2011, Volume: 157, Issue:2

    Topics: Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Guanine; Humans; Organophosphonates; Valganciclovir; Virus Replication

2011
Prevention and management of CMV-related problems after hematopoietic stem cell transplantation.
    Bone marrow transplantation, 2002, Volume: 29, Issue:8

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Organophosphorus Compounds; Risk Factors

2002
Clinical and biologic aspects of human cytomegalovirus resistance to antiviral drugs.
    Human immunology, 2004, Volume: 65, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Antiretroviral Therapy, Highly Active; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA Mutational Analysis; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins; Virus Replication

2004
[Mechanism of drug-resistance in human cytomegalovirus].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Feb-28, Volume: 65 Suppl 2 Pt. 1

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins

2007
Cidofovir.
    Drugs, 1996, Volume: 52, Issue:2

    Topics: Animals; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Resistance, Microbial; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds

1996
Therapeutic options for resistant cytomegalovirus retinitis.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Volume: 14 Suppl 1

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Infusions, Intravenous; Organophosphonates; Organophosphorus Compounds; Recurrence; Thionucleotides

1997
Resistance to antivirals in human cytomegalovirus: mechanisms and clinical significance.
    Microbiologia (Madrid, Spain), 1997, Volume: 13, Issue:3

    Topics: Antiviral Agents; Cidofovir; Codon; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genes, Viral; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins; Viral Structural Proteins

1997
[Recent advances in antiviral drugs--antiviral agents to HCMV, HHV-6, and HHV-7].
    Nihon rinsho. Japanese journal of clinical medicine, 1998, Volume: 56, Issue:1

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Purines; Thymidine Kinase

1998
Cidofovir. Review of current and potential clinical uses.
    Advances in experimental medicine and biology, 1999, Volume: 458

    Topics: AIDS-Related Opportunistic Infections; Animals; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds

1999
Cytomegalovirus infection following stem cell transplantation.
    Haematologica, 1999, Volume: 84 Suppl EHA-4

    Topics: Acyclovir; Antibodies, Viral; Antiviral Agents; Blood Donors; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Immunocompromised Host; Immunotherapy, Adoptive; Leukocyte Transfusion; Organophosphonates; Organophosphorus Compounds; Premedication; Risk Factors; Tissue Donors; Transfusion Reaction; Virus Latency

1999
Progress in understanding cytomegalovirus drug resistance.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2001, Volume: 21, Issue:3

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Forecasting; Foscarnet; Ganciclovir; Humans; Incidence; Organophosphonates; Organophosphorus Compounds

2001
Cytomegalovirus drug resistance and clinical implications.
    Transplant infectious disease : an official journal of the Transplantation Society, 2001, Volume: 3 Suppl 2

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Incidence; Organ Transplantation; Organophosphonates; Organophosphorus Compounds; Risk Factors

2001
Value of animal models to evaluate agents with potential activity against human cytomegalovirus.
    Transplantation proceedings, 1991, Volume: 23, Issue:3 Suppl 3

    Topics: Acyclovir; Animals; Antiviral Agents; Cell Division; Cell Survival; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Fibroblasts; Ganciclovir; Humans; Mice; Organophosphonates; Organophosphorus Compounds; Virus Replication

1991

Trials

2 trial(s) available for cidofovir anhydrous and Cytomegalovirus

ArticleYear
Susceptibility of human cytomegalovirus to cidofovir is unchanged after limited in vivo exposure to various regimens of drug.
    The Journal of infectious diseases, 1996, Volume: 173, Issue:4

    Topics: Adult; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds

1996
Cidofovir for cytomegalovirus-preemptive therapy in stem cell transplant recipients.
    Blood, 2001, Sep-01, Volume: 98, Issue:5

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Myelodysplastic Syndromes; Organophosphonates; Organophosphorus Compounds; Prospective Studies; Transplantation, Homologous; Treatment Failure; Viremia; Virus Activation

2001

Other Studies

135 other study(ies) available for cidofovir anhydrous and Cytomegalovirus

ArticleYear
Synthesis and antiviral activity of the nucleotide analogue (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:7

    Topics: Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Cidofovir; Cytomegalovirus; Cytosine; Cytosine Nucleotides; Female; Guinea Pigs; Humans; Mice; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Vero Cells

1989
Synthesis and antiviral activity of pyranosylphosphonic acid nucleotide analogues.
    Journal of medicinal chemistry, 1996, Mar-15, Volume: 39, Issue:6

    Topics: Antiviral Agents; Cytomegalovirus; Herpesvirus 2, Human; Nucleotides

1996
Identification of novel nucleotide phosphonate analogs with potent anti-HCMV activity.
    Bioorganic & medicinal chemistry letters, 1998, Dec-15, Volume: 8, Issue:24

    Topics: Antiviral Agents; Cytomegalovirus; Microbial Sensitivity Tests; Nucleotides; Organophosphorus Compounds; Stereoisomerism; Structure-Activity Relationship

1998
The cyclohexene ring system as a furanose mimic: synthesis and antiviral activity of both enantiomers of cyclohexenylguanine.
    Journal of medicinal chemistry, 2000, Feb-24, Volume: 43, Issue:4

    Topics: Animals; Antiviral Agents; Cyclohexanes; Cytomegalovirus; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Humans; Models, Molecular; Molecular Mimicry; Purine Nucleosides; Stereoisomerism; Structure-Activity Relationship

2000
Nonnucleoside human cytomegalovirus inhibitors: synthesis and antiviral evaluation of (chlorophenylmethyl)benzothiadiazine dioxide derivatives.
    Journal of medicinal chemistry, 2000, Aug-24, Volume: 43, Issue:17

    Topics: Animals; Anti-HIV Agents; Antiviral Agents; Benzothiadiazines; Chlorocebus aethiops; Cyclic S-Oxides; Cytomegalovirus; HeLa Cells; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Structure-Activity Relationship; T-Lymphocytes; Vero Cells

2000
Synthesis and antiviral/antiproliferative activity of some N-sulphonylbenzimidazoles.
    Bioorganic & medicinal chemistry letters, 2002, Oct-07, Volume: 12, Issue:19

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Benzimidazoles; Cytomegalovirus; Drug Screening Assays, Antitumor; Herpesvirus 3, Human; Humans; Mice; Structure-Activity Relationship; T-Lymphocytes; Tumor Cells, Cultured; Viral Plaque Assay

2002
Discovery of a new family of inhibitors of human cytomegalovirus (HCMV) based upon lipophilic alkyl furano pyrimidine dideoxy nucleosides: action via a novel non-nucleosidic mechanism.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Antiviral Agents; Cell Line; Cytomegalovirus; Furans; Humans; Pyrimidine Nucleosides; Structure-Activity Relationship; Virus Replication

2004
Synthesis and anti-HCMV activity of 1-acyl-beta-lactams and 1-acylazetidines derived from phenylalanine.
    Bioorganic & medicinal chemistry letters, 2004, May-03, Volume: 14, Issue:9

    Topics: Antiviral Agents; Azetidines; Cytomegalovirus; Lactams

2004
The novel L- and D-amino acid derivatives of hydroxyurea and hydantoins: synthesis, X-ray crystal structure study, and cytostatic and antiviral activity evaluations.
    Journal of medicinal chemistry, 2005, Jan-27, Volume: 48, Issue:2

    Topics: Amino Acids; Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Line, Tumor; Crystallography, X-Ray; Cytomegalovirus; Drug Screening Assays, Antitumor; Herpesvirus 3, Human; Humans; Hydantoins; Hydroxyurea; Stereoisomerism; Structure-Activity Relationship

2005
Synthesis, X-ray crystal structure study, and cytostatic and antiviral evaluation of the novel cycloalkyl-N-aryl-hydroxamic acids.
    Journal of medicinal chemistry, 2005, Feb-10, Volume: 48, Issue:3

    Topics: Acetamides; Adamantane; Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Line, Tumor; Crystallography, X-Ray; Cytomegalovirus; Drug Screening Assays, Antitumor; Humans; Hydroxamic Acids; Mice; Molecular Structure; Structure-Activity Relationship

2005
Design and synthesis of a potent macrocyclic 1,6-naphthyridine anti-human cytomegalovirus (HCMV) inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6

    Topics: Antiviral Agents; Cytomegalovirus; Drug Design; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Models, Chemical; Models, Molecular; Molecular Structure; Naphthyridines

2005
From 1-acyl-beta-lactam human cytomegalovirus protease inhibitors to 1-benzyloxycarbonylazetidines with improved antiviral activity. A straightforward approach to convert covalent to noncovalent inhibitors.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Alanine; Antiviral Agents; Azetidines; Cells, Cultured; Cytomegalovirus; Humans; Lactams; Protease Inhibitors; Structure-Activity Relationship

2005
Inactivation of S-adenosyl-L-homocysteine hydrolase by 6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine and 6'-chloro-6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine. Antiviral and cytotoxic effects.
    Journal of medicinal chemistry, 2006, Feb-23, Volume: 49, Issue:4

    Topics: Adenosylhomocysteinase; Antineoplastic Agents; Antiviral Agents; Cells, Cultured; Cytomegalovirus; Deoxyadenosines; Herpesvirus 3, Human; Humans; Nucleosides; Stereoisomerism; Structure-Activity Relationship

2006
Synthesis and antiviral evaluation of alkoxyalkyl derivatives of 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine against cytomegalovirus and orthopoxviruses.
    Journal of medicinal chemistry, 2006, Mar-23, Volume: 49, Issue:6

    Topics: Adenine; Antiviral Agents; Cell Line; Cytomegalovirus; Esters; Humans; Organophosphonates; Orthopoxvirus; Stereoisomerism; Structure-Activity Relationship

2006
Discovery of a novel series of inhibitors of human cytomegalovirus primase.
    Bioorganic & medicinal chemistry letters, 2006, Sep-15, Volume: 16, Issue:18

    Topics: Antiviral Agents; Bone Marrow; Cell Line; Cytomegalovirus; DNA Primase; Enzyme Inhibitors; Humans; Molecular Structure; Pyrimidines; Structure-Activity Relationship

2006
Multidrug resistance conferred by novel DNA polymerase mutations in human cytomegalovirus isolates.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; Drug Resistance, Multiple; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genotype; Humans; Immunocompromised Host; Mutation; Organophosphonates; Phenotype; Viral Proteins; Virus Replication

2007
SAR studies on a novel series of human cytomegalovirus primase inhibitors.
    Bioorganic & medicinal chemistry letters, 2007, Apr-15, Volume: 17, Issue:8

    Topics: Administration, Oral; Animals; Antiviral Agents; Biological Availability; Cytomegalovirus; DNA Primase; DNA Replication; Drug-Related Side Effects and Adverse Reactions; Humans; Inhibitory Concentration 50; Pyrimidines; Rats; Structure-Activity Relationship; Viral Load

2007
Growth and drug resistance phenotypes resulting from cytomegalovirus DNA polymerase region III mutations observed in clinical specimens.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11

    Topics: Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genotype; Humans; Mutation; Phenotype

2007
Influence of 6 or 8-substitution on the antiviral activity of 3-phenethylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (HCMV) and varicella-zoster virus (VZV).
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Antiviral Agents; Cell Line; Cell Survival; Cytomegalovirus; Dose-Response Relationship, Drug; Herpesvirus 3, Human; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Pyridines; Stereoisomerism; Structure-Activity Relationship

2007
4"-Benzoylureido-TSAO derivatives as potent and selective non-nucleoside HCMV inhibitors. Structure-activity relationship and mechanism of antiviral action.
    Journal of medicinal chemistry, 2008, Sep-25, Volume: 51, Issue:18

    Topics: Antiviral Agents; Cell Line; Cytomegalovirus; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Thymidine; Urea

2008
Influence of 6- or 8-substitution on the antiviral activity of 3-arylalkylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (CMV) and varicella-zoster virus (VZV): part II.
    Bioorganic & medicinal chemistry, 2008, Nov-01, Volume: 16, Issue:21

    Topics: Antiviral Agents; Cell Survival; Cells, Cultured; Cytomegalovirus; Cytomegalovirus Infections; Herpes Zoster; Herpesvirus 3, Human; Humans; Imidazoles; Lung; Molecular Structure; Pyridines; Structure-Activity Relationship

2008
4-Benzyloxy-gamma-sultone derivatives: discovery of a novel family of non-nucleoside inhibitors of human cytomegalovirus and varicella zoster virus.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cytomegalovirus; Herpesvirus 3, Human; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Naphthalenesulfonates; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Virus Replication

2009
Broad-spectrum antiviral activity including human immunodeficiency and hepatitis C viruses mediated by a novel retinoid thiosemicarbazone derivative.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:5

    Topics: Anti-Bacterial Agents; Benzaldehydes; Cell Line, Tumor; Chromatography, Thin Layer; Cytomegalovirus; Hepacivirus; Herpesvirus 3, Human; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Retinoids; Stereoisomerism; Structure-Activity Relationship; Thiosemicarbazones

2011
New prodrugs of Adefovir and Cidofovir.
    Bioorganic & medicinal chemistry, 2011, Jun-01, Volume: 19, Issue:11

    Topics: Adenine; Animals; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytomegalovirus; Cytosine; Herpesvirus 3, Human; HIV; Humans; Organophosphonates; Prodrugs; Simplexvirus

2011
Synthesis, transport and antiviral activity of Ala-Ser and Val-Ser prodrugs of cidofovir.
    Bioorganic & medicinal chemistry letters, 2011, Jul-01, Volume: 21, Issue:13

    Topics: Administration, Oral; Alanine; Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Molecular Structure; Organophosphonates; Peptides; Prodrugs; Rats; Serine; Valine

2011
Tyrosine-based 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) prodrugs: synthesis, stability, antiviral activity, and in vivo transport studies.
    Journal of medicinal chemistry, 2011, Aug-25, Volume: 54, Issue:16

    Topics: Adenine; Animals; Antiviral Agents; Area Under Curve; Biological Availability; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cidofovir; Cowpox virus; Cytomegalovirus; Cytosine; Fibroblasts; Herpesvirus 1, Human; Humans; Inhibitory Concentration 50; Mice; Models, Chemical; Molecular Structure; Organophosphonates; Prodrugs; Rats; Tyrosine; Vaccinia virus

2011
Synthesis and antiviral activity of 6-deoxycyclopropavir, a new prodrug of cyclopropavir.
    Bioorganic & medicinal chemistry, 2012, Apr-15, Volume: 20, Issue:8

    Topics: Administration, Oral; Animals; Antiviral Agents; Cowpox virus; Cyclopropanes; Cytomegalovirus; Guanine; Hepatitis B virus; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 4, Human; HIV-1; Humans; Male; Mice; Mice, Inbred BALB C; Mice, SCID; Microbial Sensitivity Tests; Molecular Structure; Prodrugs; Vaccinia virus

2012
Synthesis and anti-HCMV activity of 1-[ω-(phenoxy)alkyl]uracil derivatives and analogues thereof.
    Bioorganic & medicinal chemistry, 2013, Jul-15, Volume: 21, Issue:14

    Topics: Antiviral Agents; Cells, Cultured; Cytomegalovirus; Humans; Receptors, Virus; Structure-Activity Relationship; Uracil; Virus Replication

2013
Design, antiviral and cytostatic properties of isoxazolidine-containing amonafide analogues.
    Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13

    Topics: Acrylamides; Adenine; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Survival; Cycloaddition Reaction; Cytomegalovirus; Cytostatic Agents; Drug Design; Enterovirus; Humans; Isoxazoles; Naphthalimides; Nitrogen Oxides; Organophosphonates; Phlebovirus; Simplexvirus; Structure-Activity Relationship; Vaccinia virus

2015
Novel halogenated 3-deazapurine, 7-deazapurine and alkylated 9-deazapurine derivatives of L-ascorbic or imino-L-ascorbic acid: Synthesis, antitumour and antiviral activity evaluations.
    European journal of medicinal chemistry, 2015, Sep-18, Volume: 102

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Ascorbic Acid; Cell Line; Cell Proliferation; Cytomegalovirus; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fibroblasts; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Purines; Structure-Activity Relationship

2015
Toward the discovery of dual HCMV-VZV inhibitors: Synthesis, structure activity relationship analysis, and cytotoxicity studies of long chained 2-uracil-3-yl-N-(4-phenoxyphenyl)acetamides.
    Bioorganic & medicinal chemistry, 2015, Nov-01, Volume: 23, Issue:21

    Topics: Acetamides; Antiviral Agents; Cell Line; Cell Proliferation; Cytomegalovirus; DNA Viruses; Drug Evaluation, Preclinical; Herpesvirus 3, Human; Humans; RNA Viruses; Structure-Activity Relationship; Uracil; Virus Replication

2015
Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs.
    Journal of medicinal chemistry, 2017, 07-27, Volume: 60, Issue:14

    Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Aspartic Acid; Cell Line; Cytomegalovirus; Drug Resistance, Viral; Drug Stability; Esters; Hepatitis B virus; Herpesvirus 3, Human; Humans; Hydrogen-Ion Concentration; Microsomes, Liver; Nucleosides; Organophosphonates; Prodrugs; Stereoisomerism; Structure-Activity Relationship

2017
New prodrugs of two pyrimidine acyclic nucleoside phosphonates: Synthesis and antiviral activity.
    Bioorganic & medicinal chemistry, 2017, 09-01, Volume: 25, Issue:17

    Topics: Antiviral Agents; Cell Line; Cytomegalovirus; Herpesvirus 3, Human; Humans; Organophosphonates; Prodrugs; Pyrimidine Nucleosides; Simplexvirus

2017
Synthesis of a 3'-C-ethynyl-β-d-ribofuranose purine nucleoside library: Discovery of C7-deazapurine analogs as potent antiproliferative nucleosides.
    European journal of medicinal chemistry, 2018, Sep-05, Volume: 157

    Topics: Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Proliferation; Cytomegalovirus; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Purine Nucleosides; Small Molecule Libraries; Structure-Activity Relationship; Vaccinia virus

2018
Opposite effects of cytomegalovirus UL54 exonuclease domain mutations on acyclovir and cidofovir susceptibility.
    Antiviral research, 2021, Volume: 195

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exonucleases; Ganciclovir; Mutation; Viral Proteins

2021
Cidofovir, a choice for salvage treatment of cytomegalovirus infection in patients with haploidentical hematopoietic stem cell transplantation.
    Transplant infectious disease : an official journal of the Transplantation Society, 2022, Volume: 24, Issue:2

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Retrospective Studies; Salvage Therapy

2022
Intra-host diversity of drug-resistant cytomegalovirus: A case report of cytomegalovirus infection after allogeneic hematopoietic cell transplantation.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2022, Volume: 28, Issue:10

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Mutation; Phosphotransferases (Alcohol Group Acceptor)

2022
Genotypic and Phenotypic Study of Antiviral Resistance Mutations in Refractory Cytomegalovirus Infection.
    The Journal of infectious diseases, 2022, 11-01, Volume: 226, Issue:9

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Ganciclovir; Humans; Mutation; Phenotype; Viral Proteins

2022
Prevalence of cytomegalovirus antiviral drug resistance in transplant recipients.
    Antiviral research, 2023, Volume: 215

    Topics: Antiviral Agents; Benzimidazoles; Cidofovir; Cytomegalovirus; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Prevalence; Transplant Recipients; Viral Proteins

2023
Artemisone demonstrates synergistic antiviral activity in combination with approved and experimental drugs active against human cytomegalovirus.
    Antiviral research, 2019, Volume: 172

    Topics: Acetates; Antiviral Agents; Artemisinins; Benzimidazoles; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Interactions; Drug Synergism; Drugs, Investigational; Female; Ganciclovir; Humans; Organ Culture Techniques; Organophosphonates; Placenta; Pregnancy; Quinazolines; Ribonucleosides

2019
Multidrug-resistant cytomegalovirus infection in a patient with granulomatosis with polyangiitis during immunosuppressive treatment.
    Antiviral therapy, 2020, Volume: 25, Issue:2

    Topics: Antiviral Agents; Cidofovir; Cyclophosphamide; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Multiple, Viral; Female; Ganciclovir; Granulomatosis with Polyangiitis; Humans; Immunosuppressive Agents; Middle Aged; Prednisone

2020
In vitro co-infection by cytomegalovirus improves the antiviral activity of ganciclovir against human adenovirus.
    International journal of antimicrobial agents, 2020, Volume: 56, Issue:2

    Topics: A549 Cells; Adenovirus Infections, Human; Adenoviruses, Human; Antiviral Agents; Cell Line; Cidofovir; Coinfection; Cytomegalovirus; DNA, Viral; Ganciclovir; Humans; Inhibitory Concentration 50; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor)

2020
Outcomes of transplant recipients treated with cidofovir for resistant or refractory cytomegalovirus infection.
    Transplant infectious disease : an official journal of the Transplantation Society, 2021, Volume: 23, Issue:3

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Ganciclovir; Humans; Retrospective Studies; Transplant Recipients

2021
Antiviral Drugs Against Herpesviruses.
    Advances in experimental medicine and biology, 2021, Volume: 1322

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Drug Resistance, Viral; Humans; Simplexvirus

2021
Epidemiology and Outcome of Ganciclovir-Resistant Cytomegalovirus Infection After Solid Organ Transplantation: A Single Transplant Center Experience in Thailand.
    Transplantation proceedings, 2017, Volume: 49, Issue:5

    Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Female; Foscarnet; Ganciclovir; Humans; Kidney Transplantation; Liver Transplantation; Male; Middle Aged; Mutation; Organ Transplantation; Organophosphonates; Postoperative Complications; Real-Time Polymerase Chain Reaction; Retrospective Studies; Thailand; Young Adult

2017
Ganciclovir Dosing Strategies and Development of Cytomegalovirus Resistance in a Kidney Transplant Recipient: A Case Report.
    Transplantation proceedings, 2017, Volume: 49, Issue:7

    Topics: Aged; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Immunoglobulins; Immunoglobulins, Intravenous; Isoxazoles; Kidney; Kidney Transplantation; Leflunomide; Male; Organophosphonates; Postoperative Complications; Tissue Donors

2017
Intracellular trafficking and therapeutic outcome of multiwalled carbon nanotubes modified with cyclodextrins and polyethylenimine.
    Colloids and surfaces. B, Biointerfaces, 2018, Mar-01, Volume: 163

    Topics: Animals; Antiviral Agents; beta-Cyclodextrins; Biological Transport; Chlorocebus aethiops; Cidofovir; Cytomegalovirus; Cytosine; Drug Carriers; Drug Liberation; Green Fluorescent Proteins; Kinetics; Lysosomes; Nanotubes, Carbon; Organophosphonates; Plasmids; Polyethyleneimine; Rhodamines; Vero Cells

2018
In vitro evaluation of current and novel antivirals in combination against human cytomegalovirus.
    Antiviral research, 2018, Volume: 158

    Topics: Antiviral Agents; Benzimidazoles; Cell Line; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Antagonism; Drug Combinations; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Endodeoxyribonucleases; Fibroblasts; Foscarnet; Ganciclovir; Guanine; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Ribonucleosides; Viral Proteins; Virus Replication

2018
Selection and recombinant phenotyping of a novel CMX001 and cidofovir resistance mutation in human cytomegalovirus.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7

    Topics: Amino Acid Sequence; Antiviral Agents; Base Sequence; Cells, Cultured; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phenotype; Sequence Analysis, DNA

2013
Generation and characterization of a GCV resistant HCMV UL97-mutation and a drug sensitive UL54-mutation.
    Antiviral research, 2013, Volume: 100, Issue:3

    Topics: Antiviral Agents; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Foscarnet; Ganciclovir; Genes, Viral; Humans; Mutagenesis; Mutation, Missense; Organophosphonates; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Viral Proteins

2013
Cytomegalovirus mutants resistant to ganciclovir and cidofovir differ in susceptibilities to synguanol and its 6-ether and 6-thioether derivatives.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:3

    Topics: Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytosine; Drug Resistance, Multiple, Viral; Foscarnet; Ganciclovir; Genotype; Guanine; Mutation; Organophosphonates

2014
UL54 foscarnet mutation in an hematopoietic stem cell transplant recipient with cytomegalovirus disease.
    Transplant infectious disease : an official journal of the Transplantation Society, 2014, Volume: 16, Issue:2

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Mutation; Organophosphonates; Viral Proteins

2014
Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; High-Throughput Nucleotide Sequencing; Humans; Immunocompromised Host; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mutation; Organophosphonates; Pneumonia, Viral; Time Factors; Viral Proteins; Virus Replication

2014
Identification of newly detected, drug-related HCMV UL97- and UL54-mutations using a modified plaque reduction assay.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2015, Volume: 69

    Topics: Adult; Antiviral Agents; Cell Line; Child; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Female; Ganciclovir; Genotype; Humans; Infant; Male; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins

2015
Novel Cytomegalovirus UL54 DNA Polymerase Gene Mutations Selected In Vitro That Confer Brincidofovir Resistance.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Gene Expression; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Protein Domains; Viral Proteins

2016
Identification of resistance-associated HCMV UL97- and UL54-mutations and a UL97-polymporphism with impact on phenotypic drug-resistance.
    Antiviral research, 2016, Volume: 131

    Topics: Adolescent; Adult; Antiviral Agents; Child; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genotype; Humans; Immunocompromised Host; Infant; Middle Aged; Mutation; Organophosphonates; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Polymorphism, Genetic; Viral Proteins

2016
Synthesis and Ativiral Activity of 5-(Benzylthio)-4-carbamyl-1,2,3-triazoles Against Human Cytomegalovirus (CMV) and Varicella-zoster Virus (VZV).
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2017, Volume: 13, Issue:5

    Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytomegalovirus; Cytosine; Ganciclovir; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Organophosphonates; Thymidine Kinase; Triazoles

2017
Case report: persistent cytomegalovirus (CMV) infection after haploidentical hematopoietic stem cell transplantation using in vivo alemtuzumab: emergence of resistant CMV due to mutations in the UL97 and UL54 genes.
    Journal of medical virology, 2008, Volume: 80, Issue:10

    Topics: Alemtuzumab; Anemia, Refractory, with Excess of Blasts; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antiviral Agents; Base Sequence; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Microbial Sensitivity Tests; Middle Aged; Molecular Sequence Data; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Viral Proteins; Virus Activation

2008
Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:1

    Topics: Alkaline Phosphatase; Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exonucleases; Foscarnet; Ganciclovir; Genes, Reporter; Genotype; Guanine; Humans; Inhibitory Concentration 50; Mutation; Organophosphonates; Phenotype; Viral Proteins; Virus Replication

2012
Ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with wild-type CMV in her plasma.
    Journal of clinical microbiology, 2012, Volume: 50, Issue:5

    Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA, Viral; Drug Resistance, Viral; Eye; Female; Foscarnet; Ganciclovir; Humans; Organophosphonates; Plasma; Sequence Analysis, DNA

2012
Case report: Multidrug-resistant cytomegalovirus in a modified multivisceral transplant recipient.
    Transplantation, 2012, Apr-15, Volume: 93, Issue:7

    Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Multiple, Viral; Female; Foscarnet; Ganciclovir; Humans; Immunosuppressive Agents; Intestine, Small; Isoxazoles; Kidney Transplantation; Leflunomide; Organophosphonates; Pancreas Transplantation; Recurrence; Stomach; Treatment Outcome

2012
Alkoxyalkyl esters of cidofovir and cyclic cidofovir exhibit multiple-log enhancement of antiviral activity against cytomegalovirus and herpesvirus replication in vitro.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:8

    Topics: Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Fibroblasts; Guinea Pigs; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Liposomes; Mice; Organophosphonates; Organophosphorus Compounds; Rats; Structure-Activity Relationship; Viral Plaque Assay; Virus Replication

2002
Prevention of cytomegalovirus disease in hematopoietic stem cell transplantation.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Oct-15, Volume: 35, Issue:8

    Topics: Acyclovir; Antiviral Agents; Chemoprevention; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Risk Factors; Transplantation, Autologous; Transplantation, Homologous; Valacyclovir; Valganciclovir; Valine

2002
Synergy of bovine lactoferrin with the anti-cytomegalovirus drug cidofovir in vitro.
    Antiviral research, 2003, Volume: 58, Issue:2

    Topics: Acyclovir; Animals; Antiviral Agents; Cattle; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Drug Synergism; Foscarnet; Ganciclovir; Inhibitory Concentration 50; Lactoferrin; Organophosphonates; Organophosphorus Compounds

2003
Human cytomegalovirus double resistance in a donor-positive/recipient-negative lung transplant patient with an impaired CD4-mediated specific immune response.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 53, Issue:3

    Topics: Antigens, Viral; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cidofovir; Cytokines; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Resistance, Viral; Ganciclovir; Humans; Immunity, Cellular; Lung; Lung Transplantation; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds

2004
Comparison of sequential cytomegalovirus isolates in a patient with lymphoma and failing antiviral therapy.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2004, Volume: 29, Issue:4

    Topics: Aged; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Resistance, Viral; Evolution, Molecular; Female; Foscarnet; Ganciclovir; Humans; Lymphoma, T-Cell; Molecular Epidemiology; Mutation, Missense; Organophosphonates; Organophosphorus Compounds; Polymorphism, Restriction Fragment Length; Sequence Analysis, DNA

2004
Susceptibility of porcine cytomegalovirus to antiviral drugs.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 53, Issue:6

    Topics: Animals; Antiviral Agents; Cell Survival; Cidofovir; Cytomegalovirus; Cytosine; DNA, Viral; Fluorescent Antibody Technique, Indirect; Foscarnet; Ganciclovir; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Polymerase Chain Reaction; Swine; Virus Replication

2004
Efficacy of ganciclovir and cidofovir against human cytomegalovirus replication in SCID mice implanted with human retinal tissue.
    Antiviral research, 2004, Volume: 63, Issue:1

    Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Transplantation, Heterologous; Virus Replication

2004
Oral activity of ether lipid ester prodrugs of cidofovir against experimental human cytomegalovirus infection.
    The Journal of infectious diseases, 2004, Aug-01, Volume: 190, Issue:3

    Topics: Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Esters; Ether; Humans; Lipids; Male; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Prodrugs; Treatment Outcome

2004
Oral treatment of murine cytomegalovirus infections with ether lipid esters of cidofovir.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:9

    Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Esters; Female; Injections, Intraperitoneal; Injections, Intravenous; Lipids; Mice; Mice, Inbred BALB C; Organophosphonates; Organophosphorus Compounds; Structure-Activity Relationship; Viral Load

2004
Novel chemical class of pUL97 protein kinase-specific inhibitors with strong anticytomegaloviral activity.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:11

    Topics: Antiviral Agents; Blotting, Western; Cell Line; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Viral; Enzyme Inhibitors; Ganciclovir; Humans; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Quinazolines; Viral Plaque Assay; Virus Replication

2004
Comparison of the antiviral activities of alkoxyalkyl and alkyl esters of cidofovir against human and murine cytomegalovirus replication in vitro.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:2

    Topics: Animals; Anti-HIV Agents; Cells, Cultured; Cidofovir; Coloring Agents; Cytomegalovirus; Cytosine; Esters; Ethylene Glycols; Glycerol; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mice; Neutral Red; Organophosphonates; Propylene Glycols; Structure-Activity Relationship; Viral Plaque Assay; Virus Replication

2005
Murine cytomegalovirus resistant to antivirals has genetic correlates with human cytomegalovirus.
    The Journal of general virology, 2005, Volume: 86, Issue:Pt 8

    Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Ganciclovir; Guanine; Humans; Mice; Models, Molecular; Molecular Sequence Data; Muromegalovirus; Mutation; Organophosphonates; Protein Kinases; Sequence Alignment; Valacyclovir; Valine; Virus Replication

2005
Comparative activities of lipid esters of cidofovir and cyclic cidofovir against replication of herpesviruses in vitro.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:9

    Topics: Antiviral Agents; Cell Adhesion; Cell Proliferation; Cell Survival; Cells, Cultured; Cidofovir; Cyclization; Cytomegalovirus; Cytosine; Enzyme-Linked Immunosorbent Assay; Esters; Fibroblasts; Flow Cytometry; Herpesviridae; Humans; In Situ Hybridization; Organophosphonates; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Viral Plaque Assay; Virus Replication

2005
New reporter cell line to evaluate the sequential emergence of multiple human cytomegalovirus mutations during in vitro drug exposure.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:12

    Topics: Amino Acid Sequence; Antiviral Agents; Cell Line; Cidofovir; Cytomegalovirus; Cytosine; DNA Replication; DNA, Viral; Drug Resistance, Viral; Ganciclovir; Humans; Molecular Sequence Data; Mutation; Organophosphonates

2005
Inhibition of the replication of DNA viruses by phosphonylmethoxyalkyl-purines and -pyrimidines.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Adenine; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA Viruses; Organophosphonates; Simplexvirus; Virus Replication

1989
Maribavir sensitivity of cytomegalovirus isolates resistant to ganciclovir, cidofovir or foscarnet.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2006, Volume: 37, Issue:2

    Topics: Antiviral Agents; Benzimidazoles; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Ribonucleosides; Viral Proteins

2006
Leflunomide failure to control recurrent cytomegalovirus infection in the setting of renal failure after allogeneic stem cell transplantation.
    Transplant infectious disease : an official journal of the Transplantation Society, 2007, Volume: 9, Issue:1

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Therapy, Combination; Encephalitis, Viral; Fatal Outcome; Ganciclovir; Hodgkin Disease; Humans; Isoxazoles; Leflunomide; Male; Middle Aged; Organophosphonates; Peripheral Blood Stem Cell Transplantation; Postoperative Complications; Renal Insufficiency; Secondary Prevention; Treatment Failure; Virus Activation

2007
A model of human cytomegalovirus infection in severe combined immunodeficient mice.
    Antiviral research, 2007, Volume: 76, Issue:2

    Topics: Animals; Antiviral Agents; Cell Culture Techniques; Cell Line; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Gelatin Sponge, Absorbable; Humans; Male; Mice; Mice, SCID; Organophosphonates; Viral Plaque Assay

2007
Accelerated evolution of maribavir resistance in a cytomegalovirus exonuclease domain II mutant.
    Journal of virology, 2008, Volume: 82, Issue:1

    Topics: Amino Acid Sequence; Amino Acid Substitution; Antiviral Agents; Benzimidazoles; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Protein Structure, Tertiary; Ribonucleosides; Sequence Alignment; Viral Proteins

2008
Effect of oral treatment with (S)-HPMPA, HDP-(S)-HPMPA or ODE-(S)-HPMPA on replication of murine cytomegalovirus (MCMV) or human cytomegalovirus (HCMV) in animal models.
    Antiviral research, 2008, Volume: 79, Issue:2

    Topics: Adenine; Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Herpesviridae Infections; Liver; Mice; Mice, Inbred BALB C; Mice, SCID; Muromegalovirus; Organophosphonates; Survival Analysis

2008
Contrasting drug resistance phenotypes resulting from cytomegalovirus DNA polymerase mutations at the same exonuclease locus.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2008, Volume: 43, Issue:1

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exodeoxyribonucleases; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phenotype; Protein Structure, Tertiary; Viral Proteins

2008
A rapid protein A binding radioimmunoassay for the evaluation of antiviral agents.
    Journal of virological methods, 1994, Volume: 48, Issue:2-3

    Topics: Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Evaluation Studies as Topic; Ganciclovir; Humans; Interferons; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Radioimmunoassay; Staphylococcal Protein A; Time Factors; Virus Replication

1994
Activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl) cytosine against human cytomegalovirus when administered as single-bolus dose and continuous infusion in in vitro cell culture perfusion system.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:10

    Topics: Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Half-Life; Humans; Organophosphonates; Organophosphorus Compounds

1994
New inhibitors of cytomegalovirus replication: in vitro evaluation, mechanism of action, and in vivo activity.
    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1994, Volume: 56, Issue:6

    Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Ganciclovir; Herpesviridae Infections; Humans; Immunologic Deficiency Syndromes; Mice; Mice, SCID; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Virus Replication

1994
Rat cytomegalovirus-induced pneumonitis after allogeneic bone marrow transplantation: effective treatment with (S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:2

    Topics: Animals; Antigens, Viral; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Immunohistochemistry; Lung; Male; Organophosphonates; Organophosphorus Compounds; Paraffin Embedding; Pneumonia, Viral; Rats; Whole-Body Irradiation

1993
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)-cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)-guanine in the treatment of intracerebral murine cytomegalovirus infections in immunocompetent and immunodeficient mice.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1993, Volume: 12, Issue:4

    Topics: Animals; Animals, Newborn; Antiviral Agents; Brain; Brain Diseases; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Ganciclovir; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds

1993
Kinetic analysis of the interaction of cidofovir diphosphate with human cytomegalovirus DNA polymerase.
    Biochemical pharmacology, 1996, Jun-14, Volume: 51, Issue:11

    Topics: Animals; Antiviral Agents; Base Sequence; Cattle; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA; Fibroblasts; Humans; Kinetics; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Viral Proteins

1996
Current and experimental therapeutic options for cytomegalovirus disease.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Apr-15, Volume: 53, Issue:8 Suppl 2

    Topics: Administration, Oral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Delayed-Action Preparations; Foscarnet; Ganciclovir; Guanine; Humans; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds

1996
Patterns of resistance and sensitivity to antiviral compounds of drug-resistant strains of human cytomegalovirus selected in vitro.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1996, Volume: 15, Issue:7

    Topics: Acyclovir; Adenine; Antiviral Agents; Cells, Cultured; Cidofovir; Cytarabine; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Fibroblasts; Foscarnet; Humans; Lung; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid

1996
Imbalance in production of cytokines by bone marrow stromal cells following cytomegalovirus infection.
    The Journal of infectious diseases, 1996, Volume: 174, Issue:5

    Topics: Bone Marrow Cells; Cidofovir; Cytokines; Cytomegalovirus; Cytosine; Ganciclovir; Humans; Lipopolysaccharides; Organophosphonates; Organophosphorus Compounds; Stromal Cells; Virus Replication

1996
Effect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongation.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:3

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA Primers; DNA-Directed DNA Polymerase; DNA, Viral; Humans; Organophosphonates; Organophosphorus Compounds; Templates, Genetic

1997
Genetic analysis of a clinical isolate of human cytomegalovirus exhibiting resistance against both ganciclovir and cidofovir.
    Archives of virology, 1997, Volume: 142, Issue:2

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Resistance, Microbial; Ganciclovir; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Sequence Analysis, DNA

1997
High-level resistance of cytomegalovirus to ganciclovir is associated with alterations in both the UL97 and DNA polymerase genes.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:1

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance; Ganciclovir; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor)

1997
Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Male; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Recombination, Genetic; RNA-Directed DNA Polymerase; Sequence Analysis, DNA

1997
Clinical failure of CMV retinitis with intravitreal cidofovir is associated with antiviral resistance.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1998, Volume: 116, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA, Viral; Drug Resistance, Microbial; Ganciclovir; Humans; Injections; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Treatment Failure; Vitreous Body

1998
Interpreting human cytomegalovirus antiviral drug susceptibility testing: the role of mixed virus populations.
    The Journal of infectious diseases, 1998, Volume: 177, Issue:3

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds

1998
Lack of reactivation of cytomegalovirus (CMV) retinitis after stopping CMV maintenance therapy in AIDS patients with sustained elevations in CD4 T cells in response to highly active antiretroviral therapy.
    The Journal of infectious diseases, 1998, Volume: 177, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Female; HIV Protease Inhibitors; HIV-1; Humans; Male; Organophosphonates; Organophosphorus Compounds; Recurrence; Virus Activation; Virus Replication

1998
Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments.
    Journal of virology, 1998, Volume: 72, Issue:7

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genes, Viral; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Recombination, Genetic; Virus Replication

1998
A point mutation in the human cytomegalovirus DNA polymerase gene selected in vitro by cidofovir confers a slow replication phenotype in cell culture.
    Virology, 1998, Sep-01, Volume: 248, Issue:2

    Topics: Amino Acid Sequence; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Microbial; Enzyme Repression; Exonucleases; Ganciclovir; Molecular Sequence Data; Organophosphonates; Organophosphorus Compounds; Phenotype; Phosphodiesterase I; Phosphoric Diester Hydrolases; Point Mutation; Sequence Homology, Amino Acid; Viral Proteins; Virus Replication

1998
[Comparison of the in vitro sensitivity to cidofovir and ganciclovir of clinical cytomegalovirus isolates. Coordinated Action Group 11].
    Pathologie-biologie, 1998, Volume: 46, Issue:6

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Enzyme Inhibitors; Ganciclovir; Humans; Microbial Sensitivity Tests; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins

1998
Cytomegalovirus retinitis and viral resistance: 3. Culture results. CMV Retinitis and Viral Resistance Study Group.
    American journal of ophthalmology, 1998, Volume: 126, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Baltimore; Blood; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Resistance, Microbial; Female; Follow-Up Studies; Foscarnet; Ganciclovir; Humans; Male; Organophosphonates; Organophosphorus Compounds; Prognosis; Prospective Studies; Survival Rate; Urine; Viremia

1998
In vitro antiviral susceptibilities of isolates from cytomegalovirus retinitis patients receiving first- or second-line cidofovir therapy: relationship to clinical outcome.
    The Journal of infectious diseases, 1998, Volume: 178, Issue:6

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genotype; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Recurrence

1998
Cytomegalovirus iritis.
    Ophthalmic surgery and lasers, 1998, Volume: 29, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; Antibodies, Viral; Antigens, Viral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Fatal Outcome; Humans; Immunohistochemistry; Iris; Iritis; Male; Organophosphonates; Organophosphorus Compounds

1998
Comparative study of the anti-human cytomegalovirus activities and toxicities of a tetrahydrofuran phosphonate analogue of guanosine and cidofovir.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:3

    Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Cidofovir; Cytomegalovirus; Cytosine; Guanine; Guanosine; Guinea Pigs; Humans; Kidney; Male; Mice; Mice, Inbred BALB C; Organophosphonates; Organophosphorus Compounds; Phosphinic Acids; Rats; Viral Plaque Assay; Virus Replication

1999
A high throughput colorimetric cell proliferation assay for the identification of human cytomegalovirus inhibitors.
    Antiviral research, 1999, Volume: 41, Issue:1

    Topics: Antiviral Agents; Cidofovir; Colorimetry; Cytomegalovirus; Cytopathogenic Effect, Viral; Cytosine; Fibroblasts; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Tetrazolium Salts; Virus Replication

1999
Comment: cidofovir in the treatment of cytomegaloviral disease.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:6

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Organophosphonates; Organophosphorus Compounds

1999
Quantitative changes in cytomegalovirus DNAemia and genetic analysis of the UL97 and UL54 genes in AIDS patients receiving cidofovir following ganciclovir therapy.
    Journal of medical virology, 1999, Volume: 58, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Ganciclovir; Genotype; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Prospective Studies; Retinitis; Viral Load; Viral Proteins

1999
Lack of reactivation of cytomegalovirus retinitis in an AIDS patient, during and after stopping long-term cidofovir treatment: case report.
    Journal of chemotherapy (Florence, Italy), 2000, Volume: 12, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Administration Schedule; Humans; Male; Organophosphonates; Organophosphorus Compounds; Virus Activation

2000
Treatment of BK virus-associated hemorrhagic cystitis and simultaneous CMV reactivation with cidofovir.
    Bone marrow transplantation, 2000, Volume: 26, Issue:3

    Topics: Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Hematuria; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Papillomavirus Infections; Virus Activation

2000
A deletion mutation in region V of the cytomegalovirus DNA polymerase sequence confers multidrug resistance.
    The Journal of infectious diseases, 2000, Volume: 182, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Drug Resistance, Multiple; Foscarnet; Ganciclovir; Gene Deletion; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases; Transfection

2000
Fatal cytomegalovirus pneumonia after preemptive antiviral therapy in a renal transplant recipient.
    Clinical nephrology, 2000, Volume: 54, Issue:5

    Topics: Antigens, Viral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Fatal Outcome; Female; Foscarnet; Ganciclovir; Humans; Kidney Transplantation; Middle Aged; Organophosphonates; Organophosphorus Compounds; Pneumonia, Viral; Polymerase Chain Reaction; Postoperative Complications

2000
Virological, clinical, and ophthalmologic features of cytomegalovirus retinitis after hematopoietic stem cell transplantation.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Jan-15, Volume: 32, Issue:2

    Topics: Adult; Antiviral Agents; Chronic Disease; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Female; Foscarnet; Ganciclovir; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Risk Factors; Treatment Outcome; Virus Activation

2001
Enhancement of transplantation-associated atherosclerosis by CMV, which can be prevented by antiviral therapy in the form of HPMPC.
    Transplant international : official journal of the European Society for Organ Transplantation, 1994, Volume: 7 Suppl 1

    Topics: Animals; Antiviral Agents; Aorta; Arteriosclerosis; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Graft Rejection; Male; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Rats; Rats, Inbred BN; Rats, Inbred Lew; Transplantation, Homologous; Transplantation, Isogeneic; Tunica Intima; Tunica Media; Virus Replication

1994
Successful preemptive cidofovir treatment for CMV antigenemia after dose-reduced conditioning and allogeneic blood stem cell transplantation.
    Transplantation, 2001, Apr-15, Volume: 71, Issue:7

    Topics: Adult; Antigens, Viral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Feasibility Studies; Female; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Male; Middle Aged; Mycoses; Myeloablative Agonists; Organophosphonates; Organophosphorus Compounds; Phosphoproteins; Preventive Medicine; Prospective Studies; Transplantation Conditioning; Viral Matrix Proteins

2001
CMV retinitis: a clinical management update.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Algorithms; Antiviral Agents; Cidofovir; Clinical Protocols; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Injections; Organophosphonates; Organophosphorus Compounds; Patient Participation; Vitreous Body

1996
Strategies for management of cytomegalovirus (CMV) infection after allogeneic bone marrow transplantation: the "doubling of baseline CMV pp65 antigenemia" and the "cidofovir as rescue treatment approaches.
    Blood, 2001, Sep-01, Volume: 98, Issue:5

    Topics: Antigens, Viral; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Phosphoproteins; Recurrence; Salvage Therapy; Time Factors; Transplantation, Homologous; Viral Matrix Proteins; Viremia

2001
Quantification of cytomegalovirus (CMV) viral load by the hybrid capture assay allows for early detection of CMV disease in lung transplant recipients.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2001, Volume: 20, Issue:9

    Topics: Adult; Antiviral Agents; Cell Culture Techniques; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Female; Ganciclovir; Humans; Illinois; Immunization, Passive; Lung Transplantation; Male; Middle Aged; Nucleic Acid Hybridization; Organophosphonates; Organophosphorus Compounds; Predictive Value of Tests; Prospective Studies; Reagent Kits, Diagnostic; Sensitivity and Specificity; Survival Analysis; Syndrome; Viral Load

2001
Predictive efficacy of SCID-hu mouse models for treatment of human cytomegalovirus infections.
    Antiviral chemistry & chemotherapy, 2001, Volume: 12 Suppl 1

    Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Virus Replication

2001
Cidofovir as primary pre-emptive therapy for post-transplant cytomegalovirus infections.
    Bone marrow transplantation, 2001, Volume: 28, Issue:9

    Topics: Adult; Antiviral Agents; Cidofovir; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Evaluation; Eye Infections, Viral; Female; Foscarnet; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Pilot Projects; Polymerase Chain Reaction; Probenecid; Recurrence; Safety; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Uveitis, Anterior; Viral Load; Viremia; Vomiting

2001
Polymerase chain reaction-based "pre-emptive" therapy with cidofovir for cytomegalovirus reactivation in allogeneic hematopoietic stem cells transplantation recipients: a prospective study.
    Haematologica, 2002, Volume: 87, Issue:4

    Topics: Adult; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Hematopoietic Stem Cell Transplantation; Humans; Middle Aged; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Prospective Studies; Virus Activation

2002
Antiviral and immunomodulatory activity of the metal chelator ethylenediaminedisuccinic acid against cytomegalovirus in vitro and in vivo.
    Antiviral research, 2002, Volume: 55, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Antiviral Agents; Cell Adhesion; Cell Line; Chelating Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Microbial; Ethylenediamines; Herpesviridae Infections; Humans; Intercellular Adhesion Molecule-1; Jurkat Cells; Mice; Mice, SCID; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Succinates; Virus Replication

2002
In vitro antiviral activity of aphidicolin and its derivates. Synergistic effects of aphidicolin with other antiviral drugs.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:5

    Topics: Adenoviridae; Antiviral Agents; Aphidicolin; Cidofovir; Cytomegalovirus; Cytosine; Dose-Response Relationship, Drug; Drug Synergism; Herpesvirus 1, Human; Humans; Indicators and Reagents; Organophosphonates; Organophosphorus Compounds; Virus Replication

2002
Pretreatment of the host cell with 1-(S)-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) is sufficient for its antiviral effect.
    Acta virologica, 1992, Volume: 36, Issue:3

    Topics: Antigens, Viral; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytopathogenic Effect, Viral; Cytosine; Drug Administration Schedule; Humans; In Vitro Techniques; Organophosphonates; Organophosphorus Compounds; Virus Replication

1992
Phosphonomethylether compounds as antiviral agents.
    Transplantation proceedings, 1991, Volume: 23, Issue:3 Suppl 3

    Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Haplorhini; Herpes Simplex; Mice; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Structure-Activity Relationship

1991
Antiviral activity of anti-cytomegalovirus agents (HPMPC, HPMPA) assessed by a flow cytometric method and DNA hybridization technique.
    Antiviral research, 1991, Volume: 16, Issue:1

    Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cytomegalovirus; Cytosine; Flow Cytometry; Ganciclovir; Humans; Microbial Sensitivity Tests; Nucleic Acid Hybridization; Organophosphonates; Organophosphorus Compounds; Viral Plaque Assay

1991
Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro.
    Antiviral research, 1991, Volume: 16, Issue:1

    Topics: Animals; Antiviral Agents; Cidofovir; Cytarabine; Cytidine; Cytomegalovirus; Cytosine; Deoxycytidine; DNA, Viral; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured; Virus Replication

1991
Sensitive, reproducible and convenient fluorometric assay for the in vitro evaluation of anti-cytomegalovirus agents.
    Journal of virological methods, 1991, Volume: 35, Issue:1

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Esterases; Flow Cytometry; Fluoresceins; Fluorometry; Foscarnet; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Polyethylene Glycols; Suramin

1991
Comparative activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine against rat cytomegalovirus infection in vitro and in vivo.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:11

    Topics: Animals; Antiviral Agents; Cell Survival; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Guanosine Triphosphate; Humans; Male; Organophosphonates; Organophosphorus Compounds; Rats; Viral Plaque Assay; Virus Replication

1991
Comparative inhibitory effects of nucleoside analogues on different clinical isolates of human cytomegalovirus in vitro.
    The Journal of infectious diseases, 1991, Volume: 163, Issue:2

    Topics: Adenine; Adenosine; Antiviral Agents; Cell Line; Cidofovir; Cytidine; Cytomegalovirus; Cytosine; Ganciclovir; Guanosine; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Thymidine

1991
Synthesis and antiviral activity of (S)-9-[4-hydroxy-3-(phosphonomethoxy)butyl]guanine.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:6

    Topics: Adenine; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Guanine; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Viral Plaque Assay

1990
Activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) against guinea pig cytomegalovirus infection in cultured cells and in guinea pigs.
    Antiviral research, 1990, Volume: 13, Issue:5

    Topics: Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Guinea Pigs; Organ Specificity; Organophosphonates; Organophosphorus Compounds; Viral Plaque Assay; Virus Replication

1990
Inhibitory effects of potent inhibitors of human immunodeficiency virus and cytomegalovirus on the growth of human granulocyte-macrophage progenitor cells in vitro.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1990, Volume: 9, Issue:8

    Topics: Adenine; Adult; Antiviral Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Foscarnet; Ganciclovir; Granulocytes; Hematopoietic Stem Cells; HIV; Humans; Macrophages; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Zidovudine

1990
Selective inhibition of human cytomegalovirus DNA synthesis by (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine [(S)-HPMPC] and 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG).
    Virology, 1990, Volume: 179, Issue:1

    Topics: Antiviral Agents; Cell Line; Cell Survival; Cidofovir; Cytomegalovirus; Cytosine; DNA; DNA Replication; DNA, Viral; Flow Cytometry; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds

1990
(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, a potent and selective inhibitor of human cytomegalovirus replication.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:12

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds; Virus Replication

1988