Page last updated: 2024-10-25

ciclopirox and Nail Fungus

ciclopirox has been researched along with Nail Fungus in 102 studies

Research Excerpts

ExcerptRelevanceReference
"Ciclopirox 8% hydrolacquer is more active than reference ciclopirox nail lacquer in the treatment of onychomycosis."9.14An innovative water-soluble biopolymer improves efficacy of ciclopirox nail lacquer in the management of onychomycosis. ( Altmeyer, P; Baran, R; Combemale, P; Hartmane, I; Hercogova, J; Koudelkova, V; Mikazans, I; Ruzicka, T; Tosti, A, 2009)
"To evaluate the efficacy of a combination therapy of ciclopirox nail lacquer and oral terbinafine compared to oral terbinafine monotherapy for the treatment of onychomycosis caused by dermatophytes."9.11Combination of oral terbinafine and topical ciclopirox compared to oral terbinafine for the treatment of onychomycosis. ( Avner, S; Henri, T; Nir, N, 2005)
"This multicenter, open-label, uncontrolled, noncomparative, observational, postmarketing study assessed the efficacy and safety of ciclopirox nail lacquer solution 8% in 3666 patients for the treatment of onychomycosis."9.09A multicenter, open-label study of the efficacy and safety of ciclopirox nail lacquer solution 8% for the treatment of onychomycosis in patients with diabetes. ( Nietsch, KH; Seebacher, C; Ulbricht, HM, 2001)
"Ciclopirox nail lacquer solution 8%, effective and safe for the treatment of dermatophyte onychomycosis of mild-to-moderate severity, covers a broad-spectrum of organisms and also may be effective in onychomycosis caused by Candida species and nondermatophyte molds."8.81Ciclopirox nail lacquer: a brush with onychomycosis. ( Gupta, AK, 2001)
"Ciclopirox nail lacquer solution 8% is a recent addition to the armamentarium of therapies available to the physician and patient for the treatment of onychomycosis."8.80Pharmacoeconomic analysis of ciclopirox nail lacquer solution 8% and the new oral antifungal agents used to treat dermatophyte toe onychomycosis in the United States. ( Gupta, AK, 2000)
"Data from the pivotal US trials have demonstrated that ciclopirox nail lacquer 8% topical solution is significantly more effective than placebo in the treatment of onychomycosis caused by Trichophyton rubrum, and of mild to moderate toe onychomycosis without lunula involvement."8.80Ciclopirox nail lacquer topical solution 8% in the treatment of toenail onychomycosis. ( Baran, R; Fleckman, P; Gupta, AK, 2000)
"We report a case of proximal fold cellulitis in both big toes, associated with a bilateral proximal onychomycosis and an intertrigo of the fourth space due to Fusarium solani."7.73[Bilateral proximal cellulitis and onychomycosis in both big toes due to Fusarium solani]. ( Sellart-Altisent, M; Torres-Rodríguez, JM, 2006)
" Its antifungal activity has been compared to ciclopiroxolamine and sulconazole, commonly used in onychomycosis treatment and chosen because of their very different chemical structures."7.70Use of caryophyllene oxide as an antifungal agent in an in vitro experimental model of onychomycosis. ( Chaumont, JP; Michel, L; Millet-Clerc, J; Yang, D, 1999)
" Nail avulsion followed by long-term occlusive application of ciclopiroxolamine cleared the onychomycosis, whereas the sole and palm infection was resistant to ciclopiroxolamine and glutaraldehyde treatment."7.67Hendersonula toruloidea infection: successful response of onychomycosis to nail avulsion and topical ciclopiroxolamine. ( Johansson, S; Rollman, O, 1987)
"Onychomycosis is prevalent in the Canadian population, and risk factors, such as old age and diabetes, are increasing."6.43Ciclopirox nail lacquer 8% for the treatment of onychomycosis: a Canadian perspective. ( Gupta, AK; Lynch, LE; Schouten, JR, 2005)
"Ciclopirox has been formulated in a nail lacquer delivery system."6.41Dermatopharmacology of ciclopirox nail lacquer topical solution 8% in the treatment of onychomycosis. ( Bohn, M; Kraemer, KT, 2000)
"A new water-soluble formulation for a ciclopirox nail lacquer showed similar efficacy to the reference product to eradicate toenail onychomycosis and superiority in the mycological cure defined by negative culture, thus preventing reinfections and recurrences."5.69Efficacy and safety of a new medicated nail hydrolacquer in the treatment of adults with toenail onychomycosis: A randomised clinical trial. ( Bermejo, R; Briones, VG; Campos, FF; Corrales, A; Igea, SA; Martínez, H; Nieto, C; Otero-Espinar, FJ; Picas, J; Zalacain-Vicuña, AJ, 2023)
"Onychomycosis is a relatively common disease accounting for up to 50% of all nail disorders."5.36Ciclopirox nail lacquer for the treatment of onychomycosis: an open non-comparative study. ( Amichai, B; Grunwald, MH; Nathansohn, N; Shemer, A; Trau, H, 2010)
"Efinaconazole topical solution 10% and tavaborole topical solution 5% are FDA approved for the treatment of onychomycosis in children ≥6 years; ciclopirox topical solution 8% nail lacquer is approved in children ≥12 years."5.22Onychomycosis in children - review on treatment and management strategies. ( Gupta, AK; Piguet, V; Shear, NH; Venkataraman, M, 2022)
"A treatment of onychomycosis comprising chemical avulsion of the pathological nail, ciclopirox cream and nail lacquer is significantly more effective than amorolfine nail lacquer."5.17A multicenter, randomized, open-label, controlled study comparing the efficacy, safety and cost-effectiveness of a sequential therapy with RV4104A ointment, ciclopiroxolamine cream and ciclopirox film-forming solution with amorolfine nail lacquer alone in ( Ben Osman, A; Bienvenu, AL; Bulai-Livideanu, C; Cazeau, C; Coubetergues, H; Coustou, D; Doss, N; Fazaa, B; Lahfa, M; Mokthar, I; Nouira, R; Paul, C; Picot, S; Turki, H; Voisard, JJ; Zourabichvili, O, 2013)
"Ciclopirox 8% hydrolacquer is more active than reference ciclopirox nail lacquer in the treatment of onychomycosis."5.14An innovative water-soluble biopolymer improves efficacy of ciclopirox nail lacquer in the management of onychomycosis. ( Altmeyer, P; Baran, R; Combemale, P; Hartmane, I; Hercogova, J; Koudelkova, V; Mikazans, I; Ruzicka, T; Tosti, A, 2009)
"To evaluate the efficacy of a combination therapy of ciclopirox nail lacquer and oral terbinafine compared to oral terbinafine monotherapy for the treatment of onychomycosis caused by dermatophytes."5.11Combination of oral terbinafine and topical ciclopirox compared to oral terbinafine for the treatment of onychomycosis. ( Avner, S; Henri, T; Nir, N, 2005)
"This multicenter, open-label, uncontrolled, noncomparative, observational, postmarketing study assessed the efficacy and safety of ciclopirox nail lacquer solution 8% in 3666 patients for the treatment of onychomycosis."5.09A multicenter, open-label study of the efficacy and safety of ciclopirox nail lacquer solution 8% for the treatment of onychomycosis in patients with diabetes. ( Nietsch, KH; Seebacher, C; Ulbricht, HM, 2001)
"60 patients, suffering from an onychomycosis produced by molds were treated for a maximum of 6 months with ciclopirox nail lacquer (8%)."5.07[Therapy with ciclopirox lacquer of onychomycoses caused by molds]. ( Ulbricht, H; Wörz, K, 1994)
"Terbinafine is an excellent choice in diabetics due to its low risk of drug-drug interaction and proven efficacy against the typical pathogens that cause onychomycosis."4.85Onychomycosis and diabetes. ( Cantrell, W; Cathcart, S; Elewski, Be, 2009)
"The management of onychomycosis using topical agents has improved with the introduction of ciclopirox and amorolfine nail lacquers; other topical agents may be less effective."4.82The use of topical therapies to treat onychomycosis. ( Baran, R; Gupta, AK; Ryder, JE, 2003)
"Based on the patient-level analysis, we concluded that terbinafine is the most cost-effective therapy in the treatment of onychomycosis from a managed care perspective."4.82Economic analysis of oral and topical therapies for onychomycosis of the toenails and fingernails. ( Amaya, K; Arikian, S; Casciano, J; Doyle, J; Haspel, M; Kahler, K; Shear, N, 2003)
" As both amorolfine and ciclopirox have proved useful as monotherapy for onychomycosis that does not involve the nail matrix area, the purpose of this article is to check if, when combined with oral agents, the effectiveness and scope of treatment can be improved further."4.82Topical antifungal drugs for the treatment of onychomycosis: an overview of current strategies for monotherapy and combination therapy. ( Baran, R; Kaoukhov, A, 2005)
"Ciclopirox nail lacquer solution 8%, effective and safe for the treatment of dermatophyte onychomycosis of mild-to-moderate severity, covers a broad-spectrum of organisms and also may be effective in onychomycosis caused by Candida species and nondermatophyte molds."4.81Ciclopirox nail lacquer: a brush with onychomycosis. ( Gupta, AK, 2001)
"Ciclopirox nail lacquer solution 8% is a recent addition to the armamentarium of therapies available to the physician and patient for the treatment of onychomycosis."4.80Pharmacoeconomic analysis of ciclopirox nail lacquer solution 8% and the new oral antifungal agents used to treat dermatophyte toe onychomycosis in the United States. ( Gupta, AK, 2000)
"Ciclopirox nail lacquer solution 8% has been shown to be effective in the treatment of dermatophyte onychomycosis of mild to moderate severity Other studies report the effectiveness of ciclopirox nail lacquer in onychomycosis caused by Candida sp and nondermatophyte molds."4.80Ciclopirox nail lacquer solution 8% in the 21st century. ( Baran, R; Gupta, AK, 2000)
"Data from the pivotal US trials have demonstrated that ciclopirox nail lacquer 8% topical solution is significantly more effective than placebo in the treatment of onychomycosis caused by Trichophyton rubrum, and of mild to moderate toe onychomycosis without lunula involvement."4.80Ciclopirox nail lacquer topical solution 8% in the treatment of toenail onychomycosis. ( Baran, R; Fleckman, P; Gupta, AK, 2000)
"Onychomycosis is a nail infection caused by Trichophyton interdigitale and other fungi, which can be treated with topical amorolfine (AMR) and ciclopirox olamine (CPX)."4.12Reactive oxygen and nitrogen species are crucial for the antifungal activity of amorolfine and ciclopirox olamine against the dermatophyte Trichophyton interdigitale. ( Almeida, BCT; Baltazar, LM; Carmo, PHF; Dornelas, JCM; Ferreira, GF; Freitas, GJC; Peres, NTA; Santos, DA, 2022)
"There currently are 3 topical agents approved by the US Food and Drug Administration (FDA) to treat onychomycosis: tavaborole, efinaconazole, and ciclopirox."3.85Clinical trial designs for topical antifungal treatments of onychomycosis and implications on clinical practice. ( Adigun, CG; Gellings Lowe, N; Hall, SB; Joseph, WS; Rich, P; Vlahovic, TC; Zane, LT, 2017)
"In 1996, oral terbinafine joined itraconazole and fluconazole on the short list of systemic medications that could be used to treat onychomycosis (although fluconazole was not approved for this indication by the US Food and Drug Administration [FDA], it was commonly used for this purpose)."3.83Antifungal Drugs for Onychomycosis: Efficacy, Safety, and Mechanisms of Action. ( Rosen, T; Stein Gold, LF, 2016)
" Tavaborole topical solution, 5% is a novel boron-based pharmaceutical approved for the treatment of toenail onychomycosis due to Trichophyton rubrum or T mentagrophytes."3.81In Vitro Nail Penetration and Antifungal Activity of Tavaborole, a Boron-Based Pharmaceutical. ( Chanda, S; Coronado, D; Merchant, T; Zane, LT, 2015)
" He had been treated with two courses of oral terbinafine and topical 8% ciclopirox for presumed onychomycosis."3.81Trichophytum rubrum endonyx onychomycosis resistant to standard oral and topical therapies. ( Jellinek, N; Mulvaney, PM; Telang, GH, 2015)
"The in vitro activities of luliconazole, amorolfine, ciclopirox, and terbinafine were determined against 320 dermatophyte isolates from large toenails of onychomycosis patients enrolled into an ongoing phase 2b/3 clinical study."3.80Luliconazole demonstrates potent in vitro activity against dermatophytes recovered from patients with onychomycosis. ( Fothergill, AW; McCarthy, DI; Tavakkol, A; Wiederhold, NP, 2014)
"When formulated with lipid enhancers, the amount of ciclopirox in the ventral/intermediate layer and supporting bed dramatically exceed the inhibitory concentration of ciclopirox for the most common onychomycosis organisms."3.80Ciclopirox delivery into the human nail plate using novel lipid diffusion enhancers. ( Hafeez, F; Hui, X; Maibach, H; Rosenthal, B; Selner, M, 2014)
"Two nail lacquers, containing ciclopirox (CPX) or amorolfine (MRF), based on water-insoluble polymers are currently considered mainstays of topical treatment of onychomycosis."3.76Hydrosoluble medicated nail lacquers: in vitro drug permeation and corresponding antimycotic activity. ( Burgalassi, S; Chetoni, P; Ghelardi, E; Mailland, F; Monti, D; Saccomani, L; Senesi, S, 2010)
"We report a case of proximal fold cellulitis in both big toes, associated with a bilateral proximal onychomycosis and an intertrigo of the fourth space due to Fusarium solani."3.73[Bilateral proximal cellulitis and onychomycosis in both big toes due to Fusarium solani]. ( Sellart-Altisent, M; Torres-Rodríguez, JM, 2006)
"A structure-activity relationship investigation for a more efficacious therapy to treat onychomycosis, a fungal infection of the toe and fingernails, led to the discovery of a boron-containing small molecule, 5-fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2690), which is currently in clinical trials for onychomycosis topical treatment."3.73Discovery of a new boron-containing antifungal agent, 5-fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the potential treatment of onychomycosis. ( Akama, T; Alley, MR; Baker, SJ; Hernandez, V; Lau, A; Mao, W; Plattner, JJ; Sanders, V; Zhang, YK; Zhou, H, 2006)
"Amorolfine was consistently more cost-effective in terms of weighted average daily treatment cost and cost per patient cured than ciclopirox and tioconazole, when all therapies were used as indicated to treat onychomycosis."3.73Treatment costs of three nail lacquers used in onychomycosis. ( Adjadj, L; Jäckel, A; Lambert, J; Marty, JP, 2005)
"Ciclopirox nail lacquer 8% (Penlac, Aventis Pharma) was approved by the US FDA in December 1999, as a component of a comprehensive management program, for use in immunocompetent patients who have mild to moderate onychomycosis of the fingers and toes without lunula involvement due to Trichophyton rubrum."3.70Ciclopirox nail lacquer topical solution 8%. ( Gupta, AK, 2000)
" Its antifungal activity has been compared to ciclopiroxolamine and sulconazole, commonly used in onychomycosis treatment and chosen because of their very different chemical structures."3.70Use of caryophyllene oxide as an antifungal agent in an in vitro experimental model of onychomycosis. ( Chaumont, JP; Michel, L; Millet-Clerc, J; Yang, D, 1999)
"Itraconazole is an effective, broad-spectrum triazole used as continuous or pulse therapy in the treatment of onychomycosis."3.69Economic evaluation of antifungal agents in the treatment of toenail onychomycosis in Germany. ( De Doncker, P; Dubois, DJ; Eggleston, A; Gupta, AK; Haneke, E; Tormans, G; Van Doorslaer, EK; Van Rossem, K, 1996)
" Nail avulsion followed by long-term occlusive application of ciclopiroxolamine cleared the onychomycosis, whereas the sole and palm infection was resistant to ciclopiroxolamine and glutaraldehyde treatment."3.67Hendersonula toruloidea infection: successful response of onychomycosis to nail avulsion and topical ciclopiroxolamine. ( Johansson, S; Rollman, O, 1987)
"Onychomycosis is a prevalent condition affecting the United States and global population."3.01Individual Article: Updated Review of Topical Pharmaceuticals and Complementary and Alternative Medications for the Treatment of Onychomycosis in Both General and Special Populations in the United States. ( Issa, NT; Kircik, L, 2023)
" Study B: More subjects adhered to amorolfine dosage (81."2.84Patient-reported outcomes from two randomised studies comparing once-weekly application of amorolfine 5% nail lacquer to other methods of topical treatment in distal and lateral subungual onychomycosis. ( Sarkany, M; Schaller, M; Sigurgeirsson, B, 2017)
"Onychomycosis is a fungal infection of the nail unit."2.80Treatment of Onychomycosis - a Clinical Study. ( Pajaziti, L; Vasili, E, 2015)
"The conventional treatment of onychomycosis involves oral and topical therapy."2.61Novel Drug Delivery Strategies for the Treatment of Onychomycosis. ( Dhamoon, RK; Gupta, M; Popli, H, 2019)
"Onychomycosis is a fungal nail infection caused by dermatophytes, nondermatophytes, and yeast, and is the most common nail disorder seen in clinical practice."2.61Onychomycosis: Treatment and prevention of recurrence. ( Lipner, SR; Scher, RK, 2019)
"Onychomycosis is a common and difficult-to-treat fungal infection of the nail unit that gradually leads to dystrophic changes of the nail plate and nail bed."2.53Antifungal agents for onychomycosis: new treatment strategies to improve safety. ( Chanda, S; Coronado, D; Del Rosso, J; Zane, LT, 2016)
"Ciclopirox was first developed for fungal skin infections and vaginal candidiasis, and is currently well established in these indications."2.46Ciclopirox: recent nonclinical and clinical data relevant to its use as a topical antimycotic agent. ( Mailland, F; Monti, D; Subissi, A; Togni, G, 2010)
"Onychomycosis is a frequent nail disease caused by dermatophytes, yeasts, and nondermatophyte molds."2.46Onychomycosis. ( Vera-Cabrera, L; Welsh, E; Welsh, O, 2010)
"In the treatment of onychomycosis, compliance and drug interactions are important considerations, as diabetic patients frequently take concomitant medications."2.45Toenail onychomycosis in diabetic patients: issues and management. ( Budihardja, D; Freund, V; Mayser, P, 2009)
"Onychomycosis is prevalent in the Canadian population, and risk factors, such as old age and diabetes, are increasing."2.43Ciclopirox nail lacquer 8% for the treatment of onychomycosis: a Canadian perspective. ( Gupta, AK; Lynch, LE; Schouten, JR, 2005)
"Topical treatment of onychomycosis, as opposed to oral therapies, offers a distinct advantage by allowing the patient to apply medication directly to the affected area, thus decreasing the potential for serious adverse events, such as drug toxicity and drug interactions."2.42Management of onychomycosis with topicals. ( Albert, SF; Weis, ZH, 2004)
"Ciclopirox has been formulated in a nail lacquer delivery system."2.41Dermatopharmacology of ciclopirox nail lacquer topical solution 8% in the treatment of onychomycosis. ( Bohn, M; Kraemer, KT, 2000)
"rubrum."2.40Childhood white superficial onychomycosis caused by Trichophyton rubrum: report of seven cases and review of the literature. ( Lucky, AW; Ploysangam, T, 1997)
"Ciclopirox olamine is a substituted pyridone antimycotic, unrelated to the imidazole derivatives, with activity against a broad spectrum of dermatophytes, yeasts, actinomycetes, molds, other fungi, and a variety of Gram-positive and Gram-negative bacteria."2.37Ciclopirox olamine 1% cream. A preliminary review of its antimicrobial activity and therapeutic use. ( Brogden, RN; Dawson, GW; Jue, SG, 1985)
"Onychomycosis affects up to 50% of patients in the older population."1.91Evaluation of the heat sensitivity of Trichophyton rubrum and Trichophyton interdigitale. ( Braun, C; Kerschnitzki, A; Mann, M; Seidel, K; Tietze, JK; Tietze, LF, 2023)
" There are limited data on adverse events associated with the newer topical onychomycosis drugs."1.56Retrospective analysis of adverse events with topical onychomycosis medications reported to the United States Food and Drug Administration. ( Lipner, SR; Wang, Y, 2020)
"Onychomycosis is a prevailing disease caused by fungal infection of nails that mostly affects athletes and the elderly."1.43Development of ciclopirox nail lacquer with enhanced permeation and retention. ( Choi, JY; Go, TG; Han, SD; Jun, JH; Kang, MH; Kim, JO; Son, MW; Thapa, RK; Yong, CS, 2016)
"Onychomycosis is a fungal infection mostly induced by dermatophytes such as Trichophyton rubrum."1.40Comparison of the antifungal efficacy of terbinafine hydrochloride and ciclopirox olamine containing formulations against the dermatophyte Trichophyton rubrum in an infected nail plate model. ( Müller-Goymann, CC; Täuber, A, 2014)
"Onychomycosis is a relatively common disease accounting for up to 50% of all nail disorders."1.36Ciclopirox nail lacquer for the treatment of onychomycosis: an open non-comparative study. ( Amichai, B; Grunwald, MH; Nathansohn, N; Shemer, A; Trau, H, 2010)
"Treatment with terbinafine plus ciclopiroxolamine was effective."1.35Nail infection by Aspergillus ochraceopetaliformis. ( Brasch, J; Egberts, F; Jensen, JM; Tintelnot, K; Varga, J, 2009)
"Onychomycosis is a challenging fungal infection to treat topically, likely due to the unique properties of the nail plate."1.34In Vitro penetration of a novel oxaborole antifungal (AN2690) into the human nail plate. ( Akama, T; Baker, SJ; Barbadillo, S; Cashmore, AK; Hold, KM; Hui, X; Maibach, HI; Plattner, JJ; Sanders, V; Wester, RC; Zhang, YK, 2007)
"Successful treatment of onychomycosis in the infection site depends not only on achieving the minimal inhibitory concentration (MIC) of the antifungal agent, usually determined on fresh, proliferating fungal strains, but also on the effectivity against fungal spores dormant in nail keratin."1.32Action mechanisms of modern antifungal agents and resulting problems in the management of onychomycosis. ( Seebacher, C, 2003)
"The successful treatment of onychomycosis requires special knowledge of the various clinical presentations, of the differential diagnosis and of recent advances in medical mycology."1.32[Onychomycosis]. ( Reinel, D, 2004)
"Onychomycosis is often considered only as a cosmetic diagnosis."1.32Onychomycosis: current treatment options. ( Jones, ED, 2003)
"This report presents original methods to assess the bioavailability of an antifungal drug from a varnish preparation in finger nails."1.28Ciclopirox nail lacquer 8%: in vivo penetration into and through nails and in vitro effect on pig skin. ( Ceschin-Roques, CG; Hänel, H; Luc, J; Michel, G; Pruja-Bougaret, SM; Vandermander, J, 1991)

Research

Studies (102)

TimeframeStudies, this research(%)All Research%
pre-19903 (2.94)18.7374
1990's14 (13.73)18.2507
2000's38 (37.25)29.6817
2010's39 (38.24)24.3611
2020's8 (7.84)2.80

Authors

AuthorsStudies
Baker, SJ2
Zhang, YK2
Akama, T2
Lau, A1
Zhou, H1
Hernandez, V1
Mao, W1
Alley, MR1
Sanders, V2
Plattner, JJ2
Carmo, PHF1
Freitas, GJC1
Dornelas, JCM1
Almeida, BCT1
Baltazar, LM1
Ferreira, GF1
Peres, NTA1
Santos, DA1
Bellmann, T1
Luber, R1
Kischio, L1
Karl, B1
Pötzinger, Y1
Beekmann, U1
Kralisch, D1
Wiegand, C1
Fischer, D1
Zalacain-Vicuña, AJ1
Nieto, C1
Picas, J1
Martínez, H1
Bermejo, R1
Corrales, A1
Campos, FF1
Igea, SA1
Otero-Espinar, FJ1
Briones, VG1
Seidel, K1
Tietze, LF1
Braun, C1
Mann, M1
Kerschnitzki, A1
Tietze, JK1
Issa, NT1
Kircik, L1
Wang, Y1
Lipner, SR3
Endringer Pinto, F1
Bagger, C1
Kunze, G1
Joly-Tonetti, N1
Thénot, JP1
Osman-Ponchet, H1
Janfelt, C1
Gupta, AK11
Venkataraman, M1
Shear, NH1
Piguet, V1
Schaller, M4
Sigurgeirsson, B1
Sarkany, M1
Rich, P1
Vlahovic, TC1
Joseph, WS1
Zane, LT3
Hall, SB1
Gellings Lowe, N1
Adigun, CG1
Fabrizi, V1
Zacconi, I1
Principato, M1
Pesca, C1
Cruciani, D1
Crotti, S1
Papini, M1
Cutrín Gómez, E1
Anguiano Igea, S1
Delgado-Charro, MB1
Gómez Amoza, JL1
Otero Espinar, FJ1
Scher, RK3
Kline-Schoder, A1
Le, Z1
Zderic, V1
Ko, D1
Dhamoon, RK1
Popli, H1
Gupta, M1
Hafeez, F1
Hui, X2
Selner, M1
Rosenthal, B1
Maibach, H1
Paul, C1
Coustou, D1
Lahfa, M1
Bulai-Livideanu, C1
Doss, N1
Mokthar, I1
Turki, H1
Nouira, R1
Fazaa, B1
Ben Osman, A1
Zourabichvili, O1
Cazeau, C1
Coubetergues, H1
Picot, S1
Bienvenu, AL1
Voisard, JJ1
Täuber, A2
Müller-Goymann, CC2
Lipner, S1
Wiederhold, NP1
Fothergill, AW1
McCarthy, DI1
Tavakkol, A1
Coronado, D2
Merchant, T1
Chanda, S2
Pajaziti, L1
Vasili, E1
Seidl, HP1
Jäckel, A4
Müller, J2
Borelli, C3
Polak, A1
Braunsdorf, C1
Mailänder-Sanchez, D1
Mulvaney, PM1
Telang, GH1
Jellinek, N1
Hossin, B1
Rizi, K1
Murdan, S1
Shimamura, T2
Miyamae, A1
Arai, M1
Minemura, A1
Nozawa, A1
Kubota, N2
Rosen, T3
Stein Gold, LF3
Del Rosso, J1
Thapa, RK1
Choi, JY1
Go, TG1
Kang, MH1
Han, SD1
Jun, JH1
Son, MW1
Yong, CS1
Kim, JO1
Eichenfield, LF1
Friedlander, SF1
Carrillo-Muñoz, AJ1
Quindós, G1
Del Valle, O1
Santos, P1
Giusiano, G1
Guardia, C1
Eraso, E1
Ezkurra, PA1
Tur-Tur, C1
Hernández-Molina, JM1
Brasch, J1
Varga, J1
Jensen, JM1
Egberts, F1
Tintelnot, K1
Cathcart, S1
Cantrell, W1
Elewski, Be1
de Berker, D1
Baran, R6
Tosti, A1
Hartmane, I1
Altmeyer, P1
Hercogova, J1
Koudelkova, V1
Ruzicka, T1
Combemale, P1
Mikazans, I1
Mayser, P1
Freund, V1
Budihardja, D1
Monti, D4
Saccomani, L2
Chetoni, P2
Burgalassi, S2
Senesi, S1
Ghelardi, E1
Mailland, F3
Berger, U1
Walker, B1
Schmidt, S1
Weindl, G1
Shemer, A1
Nathansohn, N1
Trau, H1
Amichai, B1
Grunwald, MH1
Welsh, O1
Vera-Cabrera, L1
Welsh, E1
Traynor, MJ1
Turner, RB1
Evans, CR1
Khengar, RH1
Jones, SA1
Brown, MB1
Subissi, A2
Togni, G1
Tampucci, S1
Nagasaka, S1
Suzuki, T1
Mukai, H1
Shibuya, K1
Macura, AB1
Krzyściak, P1
Skóra, M1
Gniadek, A1
Herranz, U1
Dal Bo, L1
Cooper, EA1
Cursi, ÍB1
Silva, RT1
Succi, IB1
Bernardes-Engemann, AR1
Orofino-Costa, R1
Casciano, J1
Amaya, K1
Doyle, J1
Arikian, S1
Shear, N1
Haspel, M1
Kahler, K1
Jones, ED1
Ryder, JE1
Seebacher, C2
Epstein, E1
Daniel, CR1
Daniel, MP1
Daniel, J1
Sullivan, S1
Bell, FE1
Reinel, D1
Werschler, WP1
Bondar, G1
Armstrong, D1
Albert, SF1
Weis, ZH1
Sidou, F1
Soto, P1
Kaoukhov, A1
Schouten, JR1
Lynch, LE1
Marty, JP1
Lambert, J1
Adjadj, L1
Avner, S1
Nir, N1
Henri, T1
Sardana, K1
Garg, VK1
Manchanda, V1
Rajpal, M1
Romano, C1
Ghilardi, A1
Fimiani, M1
Torres-Rodríguez, JM1
Sellart-Altisent, M1
Figueiredo, VT1
de Assis Santos, D1
Resende, MA1
Hamdan, JS1
Wester, RC1
Barbadillo, S1
Cashmore, AK1
Hold, KM1
Maibach, HI1
Qadripur, SA1
Horn, G1
Höhler, T2
Ulbricht, H1
Wörz, K1
Cohen, PR1
Liony, C1
Joly, P1
Balguerie, X1
Fusade, T1
Lauret, P1
Rüping, KW1
Haas, PJ1
Effendy, I1
Kolczak, H1
Ossowski, B1
Van Doorslaer, EK1
Tormans, G1
Van Rossem, K1
Eggleston, A1
Dubois, DJ1
De Doncker, P1
Haneke, E1
Ploysangam, T1
Lucky, AW1
Bohn, M1
Kraemer, KT1
Fleckman, P1
Yang, D1
Michel, L1
Chaumont, JP1
Millet-Clerc, J1
Nietsch, KH1
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Galitz, J1
Ceschin-Roques, CG1
Hänel, H1
Pruja-Bougaret, SM1
Luc, J1
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Zhou, G1
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Deluol, AM1
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Johansson, S1
Jue, SG1
Dawson, GW1
Brogden, RN1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Effectiveness of Topical Amphotericin B in 30% Dimethylsulphoxide and 30% Dimethylsulphoxide in Treating of Non-dermatophytes Onychomycosis: Randomized Double Blind Controlled Trial Pilot Study[NCT03814343]Phase 419 participants (Actual)Interventional2019-01-15Completed
A Placebo Controlled, Randomized, Prospective Study to Evaluate the Efficacy and Safety of PinPointe FootLaser in Patients Who Have Failed Oral Terbinafine Treatment for Onychomycosis[NCT01920178]7 participants (Actual)Interventional2013-04-30Terminated (stopped due to Financial support of the Study withdrawn by Nuvolase, Inc ( PinPointe FootLaser) due to delayed start of the Study and inadequate subjects enrolled)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Adverse Events During and Following Each Study Treatment

(NCT01920178)
Timeframe: 12 months

Interventionparticipants (Number)
PinPointe Foot Laser0
Sham Laser Group0

Reviews

26 reviews available for ciclopirox and Nail Fungus

ArticleYear
Individual Article: Updated Review of Topical Pharmaceuticals and Complementary and Alternative Medications for the Treatment of Onychomycosis in Both General and Special Populations in the United States.
    Journal of drugs in dermatology : JDD, 2023, Sep-01, Volume: 22, Issue:9

    Topics: Ciclopirox; Humans; Onychomycosis; Pharmaceutical Preparations; Quality of Life; United States

2023
Onychomycosis in children - review on treatment and management strategies.
    The Journal of dermatological treatment, 2022, Volume: 33, Issue:3

    Topics: Administration, Topical; Adult; Antifungal Agents; Child; Ciclopirox; Humans; Onychomycosis; Terbina

2022
Onychomycosis: Treatment and prevention of recurrence.
    Journal of the American Academy of Dermatology, 2019, Volume: 80, Issue:4

    Topics: Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Ciclopirox; Fluconazole

2019
Novel Drug Delivery Strategies for the Treatment of Onychomycosis.
    Pharmaceutical nanotechnology, 2019, Volume: 7, Issue:1

    Topics: Administration, Topical; Antifungal Agents; Ciclopirox; Drug Carriers; Humans; Liposomes; Morpholine

2019
Antifungal agents for onychomycosis: new treatment strategies to improve safety.
    Dermatology online journal, 2016, Mar-16, Volume: 22, Issue:3

    Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Boron Compounds; Bridged Bicyclo C

2016
Pediatric Onychomycosis: The Emerging Role of Topical Therapy.
    Journal of drugs in dermatology : JDD, 2017, 02-01, Volume: 16, Issue:2

    Topics: Administration, Topical; Adult; Age Factors; Antifungal Agents; Child; Ciclopirox; Family; Humans; I

2017
Onychomycosis and diabetes.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2009, Volume: 23, Issue:10

    Topics: Administration, Topical; Antifungal Agents; Ciclopirox; Diabetes Complications; Humans; Morpholines;

2009
Clinical practice. Fungal nail disease.
    The New England journal of medicine, 2009, May-14, Volume: 360, Issue:20

    Topics: Administration, Oral; Administration, Topical; Aged; Antifungal Agents; Ciclopirox; Debridement; Dia

2009
Toenail onychomycosis in diabetic patients: issues and management.
    American journal of clinical dermatology, 2009, Volume: 10, Issue:4

    Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Ciclopirox; Comorbidity; Diabetes

2009
Onychomycosis.
    Clinics in dermatology, 2010, Mar-04, Volume: 28, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Antifungal Agents; Ciclopirox; Drug Administration

2010
Ciclopirox: recent nonclinical and clinical data relevant to its use as a topical antimycotic agent.
    Drugs, 2010, Nov-12, Volume: 70, Issue:16

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antifungal Agents; Candidiasis; Ciclopirox;

2010
Economic analysis of oral and topical therapies for onychomycosis of the toenails and fingernails.
    Managed care (Langhorne, Pa.), 2003, Volume: 12, Issue:3

    Topics: Adult; Antifungal Agents; Ciclopirox; Cost-Benefit Analysis; Drug Costs; Economics, Pharmaceutical;

2003
The use of topical therapies to treat onychomycosis.
    Dermatologic clinics, 2003, Volume: 21, Issue:3

    Topics: Administration, Cutaneous; Antifungal Agents; Ciclopirox; Humans; Morpholines; Onychomycosis; Pyrido

2003
Assessing treatment outcomes in toenail onychomycosis clinical trials.
    American journal of clinical dermatology, 2004, Volume: 5, Issue:3

    Topics: Antifungal Agents; Ciclopirox; Clinical Trials as Topic; Foot Dermatoses; Humans; Itraconazole; Naph

2004
Management of onychomycosis with topicals.
    Clinics in podiatric medicine and surgery, 2004, Volume: 21, Issue:4

    Topics: Administration, Topical; Antifungal Agents; Ciclopirox; Foot Dermatoses; Humans; Onychomycosis; Pyri

2004
Topical antifungal drugs for the treatment of onychomycosis: an overview of current strategies for monotherapy and combination therapy.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2005, Volume: 19, Issue:1

    Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Ciclopirox; Clinical Trials as Top

2005
Ciclopirox nail lacquer 8% for the treatment of onychomycosis: a Canadian perspective.
    Skin therapy letter, 2005, Volume: 10, Issue:7

    Topics: Antifungal Agents; Canada; Ciclopirox; Humans; Onychomycosis; Pyridones; Treatment Outcome

2005
Topical and surgical treatment of onychomycosis.
    Journal of the American Academy of Dermatology, 1994, Volume: 31, Issue:3 Pt 2

    Topics: Administration, Topical; Antifungal Agents; Ciclopirox; Combined Modality Therapy; Debridement; Foot

1994
Childhood white superficial onychomycosis caused by Trichophyton rubrum: report of seven cases and review of the literature.
    Journal of the American Academy of Dermatology, 1997, Volume: 36, Issue:1

    Topics: Allylamine; Antifungal Agents; Child; Child, Preschool; Ciclopirox; Coloring Agents; Female; Foot De

1997
Dermatopharmacology of ciclopirox nail lacquer topical solution 8% in the treatment of onychomycosis.
    Journal of the American Academy of Dermatology, 2000, Volume: 43, Issue:4 Suppl

    Topics: Administration, Topical; Animals; Antifungal Agents; Cattle; Ciclopirox; Clinical Trials as Topic; D

2000
Ciclopirox nail lacquer topical solution 8% in the treatment of toenail onychomycosis.
    Journal of the American Academy of Dermatology, 2000, Volume: 43, Issue:4 Suppl

    Topics: Administration, Topical; Adult; Aged; Analysis of Variance; Antifungal Agents; Ciclopirox; Clinical

2000
Ciclopirox nail lacquer solution 8% in the 21st century.
    Journal of the American Academy of Dermatology, 2000, Volume: 43, Issue:4 Suppl

    Topics: Administration, Topical; Antifungal Agents; Ciclopirox; Foot Dermatoses; Forecasting; Humans; Onycho

2000
Pharmacoeconomic analysis of ciclopirox nail lacquer solution 8% and the new oral antifungal agents used to treat dermatophyte toe onychomycosis in the United States.
    Journal of the American Academy of Dermatology, 2000, Volume: 43, Issue:4 Suppl

    Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Arthrodermataceae; Ciclopirox; Cos

2000
Ciclopirox nail lacquer: a brush with onychomycosis.
    Cutis, 2001, Volume: 68, Issue:2 Suppl

    Topics: Administration, Topical; Antifungal Agents; Ciclopirox; Clinical Trials as Topic; Humans; Onychomyco

2001
Treatment of dermatophyte toenail onychomycosis in the United States. A pharmacoeconomic analysis.
    Journal of the American Podiatric Medical Association, 2002, Volume: 92, Issue:5

    Topics: Administration, Topical; Antifungal Agents; Ciclopirox; Drug Costs; Foot Dermatoses; Griseofulvin; H

2002
Ciclopirox olamine 1% cream. A preliminary review of its antimicrobial activity and therapeutic use.
    Drugs, 1985, Volume: 29, Issue:4

    Topics: Animals; Antifungal Agents; Candidiasis, Cutaneous; Candidiasis, Vulvovaginal; Ciclopirox; Dermatomy

1985

Trials

13 trials available for ciclopirox and Nail Fungus

ArticleYear
Efficacy and safety of a new medicated nail hydrolacquer in the treatment of adults with toenail onychomycosis: A randomised clinical trial.
    Mycoses, 2023, Volume: 66, Issue:7

    Topics: Administration, Topical; Adult; Antifungal Agents; Ciclopirox; Foot Dermatoses; Humans; Nails; Onych

2023
Patient-reported outcomes from two randomised studies comparing once-weekly application of amorolfine 5% nail lacquer to other methods of topical treatment in distal and lateral subungual onychomycosis.
    Mycoses, 2017, Volume: 60, Issue:12

    Topics: Administration, Topical; Adult; Aged; Antifungal Agents; Ciclopirox; Drug Administration Schedule; F

2017
A multicenter, randomized, open-label, controlled study comparing the efficacy, safety and cost-effectiveness of a sequential therapy with RV4104A ointment, ciclopiroxolamine cream and ciclopirox film-forming solution with amorolfine nail lacquer alone in
    Dermatology (Basel, Switzerland), 2013, Volume: 227, Issue:2

    Topics: Adolescent; Adult; Aged; Antifungal Agents; Ciclopirox; Cost-Benefit Analysis; Drug Combinations; Dr

2013
Treatment of Onychomycosis - a Clinical Study.
    Medical archives (Sarajevo, Bosnia and Herzegovina), 2015, Volume: 69, Issue:3

    Topics: Antifungal Agents; Ciclopirox; Drug Administration Schedule; Drug Therapy, Combination; Fluconazole;

2015
An innovative water-soluble biopolymer improves efficacy of ciclopirox nail lacquer in the management of onychomycosis.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2009, Volume: 23, Issue:7

    Topics: Adult; Antifungal Agents; Biopolymers; Ciclopirox; Female; Humans; Male; Middle Aged; Onychomycosis;

2009
Nail penetration and predicted mycological efficacy of an innovative hydrosoluble ciclopirox nail lacquer vs. a standard amorolfine lacquer in healthy subjects.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2013, Volume: 27, Issue:2

    Topics: Adult; Ciclopirox; Humans; Male; Middle Aged; Morpholines; Nails; Onychomycosis; Pyridones; Referenc

2013
Comparison of visual assessments versus planimetry assessments in a large-scale clinical trial of onychomycosis.
    The Journal of dermatological treatment, 2014, Volume: 25, Issue:3

    Topics: Antifungal Agents; Ciclopirox; Diagnosis, Computer-Assisted; Foot Dermatoses; Humans; Naphthalenes;

2014
A randomized comparison of nail surface remanence of three nail lacquers, containing amorolfine 5%, ciclopirox 8% or tioconazole 28%, in healthy volunteers.
    International journal of tissue reactions, 2004, Volume: 26, Issue:1-2

    Topics: Adult; Antifungal Agents; Ciclopirox; Female; Humans; Imidazoles; Lacquer; Male; Morpholines; Nails;

2004
Combination of oral terbinafine and topical ciclopirox compared to oral terbinafine for the treatment of onychomycosis.
    The Journal of dermatological treatment, 2005, Volume: 16, Issue:5-6

    Topics: Administration, Oral; Administration, Topical; Adult; Antifungal Agents; Ciclopirox; Drug Therapy, C

2005
[On the local efficacy of ciclopiroxolamine in onychomycoses (author's transl)].
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:8A

    Topics: Adolescent; Adult; Aged; Antifungal Agents; Ciclopirox; Clinical Trials as Topic; Female; Humans; Ma

1981
[Therapy with ciclopirox lacquer of onychomycoses caused by molds].
    Mycoses, 1994, Volume: 37 Suppl 1

    Topics: Administration, Topical; Antifungal Agents; Ciclopirox; Follow-Up Studies; Humans; Lacquer; Onychomy

1994
[Treatment onychomycoses--bifonazole nail set in comparison with urea with ciclopiroxolamine formulation].
    Zeitschrift fur arztliche Fortbildung, 1993, Apr-12, Volume: 87, Issue:5

    Topics: Administration, Topical; Adult; Aged; Antifungal Agents; Ciclopirox; Female; Humans; Male; Middle Ag

1993
A multicenter, open-label study of the efficacy and safety of ciclopirox nail lacquer solution 8% for the treatment of onychomycosis in patients with diabetes.
    Cutis, 2001, Volume: 68, Issue:2 Suppl

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifungal Agents; Ciclopirox; Diabetes Com

2001

Other Studies

63 other studies available for ciclopirox and Nail Fungus

ArticleYear
Discovery of a new boron-containing antifungal agent, 5-fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the potential treatment of onychomycosis.
    Journal of medicinal chemistry, 2006, Jul-27, Volume: 49, Issue:15

    Topics: Administration, Topical; Antifungal Agents; Aspergillus fumigatus; Boron Compounds; Bridged Bicyclo

2006
Reactive oxygen and nitrogen species are crucial for the antifungal activity of amorolfine and ciclopirox olamine against the dermatophyte Trichophyton interdigitale.
    Medical mycology, 2022, Aug-18, Volume: 60, Issue:8

    Topics: Animals; Antifungal Agents; Arthrodermataceae; Ciclopirox; Ergosterol; Microbial Sensitivity Tests;

2022
Bacterial nanocellulose patches as a carrier for hydrating formulations to improve the topical treatment of nail diseases.
    International journal of pharmaceutics, 2022, Nov-25, Volume: 628

    Topics: Administration, Topical; Antifungal Agents; Ciclopirox; Excipients; Glycerol; Humans; Nail Diseases;

2022
Evaluation of the heat sensitivity of Trichophyton rubrum and Trichophyton interdigitale.
    European journal of dermatology : EJD, 2023, Feb-01, Volume: 33, Issue:1

    Topics: Ciclopirox; Hot Temperature; Humans; Onychomycosis; Powders; Trichophyton

2023
Retrospective analysis of adverse events with topical onychomycosis medications reported to the United States Food and Drug Administration.
    Archives of dermatological research, 2020, Volume: 312, Issue:8

    Topics: Administration, Topical; Adverse Drug Reaction Reporting Systems; Antifungal Agents; Boron Compounds

2020
Visualisation of penetration of topical antifungal drug substances through mycosis-infected nails by matrix-assisted laser desorption ionisation mass spectrometry imaging.
    Mycoses, 2020, Volume: 63, Issue:8

    Topics: Administration, Topical; Allylamine; Antifungal Agents; Ciclopirox; Humans; Lacquer; Morpholines; Na

2020
Clinical trial designs for topical antifungal treatments of onychomycosis and implications on clinical practice.
    Cutis, 2017, Volume: 100, Issue:4

    Topics: Administration, Cutaneous; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocycl

2017
Toenail onychomycosis by Trichophyton rubrum and concurrent infestation with Tyrophagus putrescentiae.
    Le infezioni in medicina, 2017, Dec-01, Volume: 25, Issue:4

    Topics: Aged; Agricultural Workers' Diseases; Animal Husbandry; Antifungal Agents; Ciclopirox; Diabetes Mell

2017
Microstructural alterations in the onychomycotic and psoriatic nail: Relevance in drug delivery.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2018, Volume: 128

    Topics: Administration, Topical; Adult; Antifungal Agents; Ciclopirox; Clobetasol; Foot Dermatoses; Healthy

2018
Ultrasound-Enhanced Ciclopirox Delivery for Treatment of Onychomycosis.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2018, Volume: 2018

    Topics: Administration, Topical; Antifungal Agents; Ciclopirox; Humans; Nails; Onychomycosis; Permeability;

2018
Optimizing topical therapy for onychomycosis: the importance of patient education.
    Cutis, 2018, Volume: 102, Issue:6

    Topics: Administration, Topical; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic

2018
Ciclopirox delivery into the human nail plate using novel lipid diffusion enhancers.
    Drug development and industrial pharmacy, 2014, Volume: 40, Issue:6

    Topics: Absorption, Physicochemical; Administration, Topical; Antifungal Agents; Cadaver; Ciclopirox; Dose-R

2014
Comparison of the antifungal efficacy of terbinafine hydrochloride and ciclopirox olamine containing formulations against the dermatophyte Trichophyton rubrum in an infected nail plate model.
    Molecular pharmaceutics, 2014, Jul-07, Volume: 11, Issue:7

    Topics: Animals; Antifungal Agents; Arthrodermataceae; Cattle; Chemistry, Pharmaceutical; Ciclopirox; Foot D

2014
Onychomycosis: current and future therapies.
    Cutis, 2014, Volume: 93, Issue:2

    Topics: Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Ciclopirox; Debridement

2014
Luliconazole demonstrates potent in vitro activity against dermatophytes recovered from patients with onychomycosis.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:6

    Topics: Antifungal Agents; Arthrodermataceae; Ciclopirox; Dermatomycoses; Humans; Imidazoles; Microbial Sens

2014
In Vitro Nail Penetration and Antifungal Activity of Tavaborole, a Boron-Based Pharmaceutical.
    Journal of drugs in dermatology : JDD, 2015, Volume: 14, Issue:6

    Topics: Administration, Topical; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic

2015
Sporicidal effect of amorolfine and other antimycotics used in the therapy of fungal nail infections.
    Mycoses, 2015, Volume: 58, Issue:10

    Topics: Antifungal Agents; Candida albicans; Ciclopirox; Epidermophyton; Fluconazole; Hand Dermatoses; Human

2015
Comparison of user-friendliness and treatment cost of Loceryl® vs. Ciclopoli®--a patient's perspective.
    Mycoses, 2015, Volume: 58, Issue:10

    Topics: Administration, Topical; Adult; Antifungal Agents; Ciclopirox; Foot Dermatoses; Germany; Health Care

2015
Trichophytum rubrum endonyx onychomycosis resistant to standard oral and topical therapies.
    Dermatology online journal, 2015, Sep-17, Volume: 21, Issue:9

    Topics: Administration, Cutaneous; Administration, Oral; Antifungal Agents; Ciclopirox; Drug Resistance, Mul

2015
Application of Hansen Solubility Parameters to predict drug-nail interactions, which can assist the design of nail medicines.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2016, Volume: 102

    Topics: Adolescent; Adult; Antifungal Agents; Ciclopirox; Drug Interactions; Female; Humans; Keratins; Male;

2016
[Distribution of Luliconazole in Nail Plate by In Vitro Permeation and Efficacy by Zone of Inhibition Test after Treatment of Luliconazole Nail Solution].
    Medical mycology journal, 2016, Volume: 57, Issue:1

    Topics: Administration, Topical; Antifungal Agents; Ciclopirox; Dose-Response Relationship, Drug; Drug Resis

2016
In vitro evaluation of the antifungal efficacy of poloxamer 407-based formulations in an infected nail plate model.
    International journal of pharmaceutics, 2016, May-30, Volume: 505, Issue:1-2

    Topics: Administration, Topical; Animals; Antifungal Agents; Cattle; Chemistry, Pharmaceutical; Ciclopirox;

2016
Antifungal Drugs for Onychomycosis: Efficacy, Safety, and Mechanisms of Action.
    Seminars in cutaneous medicine and surgery, 2016, Volume: 35, Issue:3 Suppl 3

    Topics: Administration, Cutaneous; Administration, Oral; Antifungal Agents; Boron Compounds; Bridged Bicyclo

2016
Introduction.
    Seminars in cutaneous medicine and surgery, 2016, Volume: 35, Issue:3 Suppl 3

    Topics: Administration, Cutaneous; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocycl

2016
Using Topical Antifungal Medications: Instructions for patients.
    Seminars in cutaneous medicine and surgery, 2016, Volume: 35, Issue:3 Suppl 3

    Topics: Administration, Cutaneous; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocycl

2016
Development of ciclopirox nail lacquer with enhanced permeation and retention.
    Archives of pharmacal research, 2016, Volume: 39, Issue:7

    Topics: Administration, Topical; Animals; Antifungal Agents; Cattle; Ciclopirox; Hoof and Claw; Humans; Lacq

2016
In vitro antifungal activity of sertaconazole nitrate against recent isolates of onychomycosis causative agents.
    Journal of chemotherapy (Florence, Italy), 2008, Volume: 20, Issue:4

    Topics: Antifungal Agents; Arthrodermataceae; Ciclopirox; Dose-Response Relationship, Drug; Fluconazole; Fun

2008
Nail infection by Aspergillus ochraceopetaliformis.
    Medical mycology, 2009, Volume: 47, Issue:6

    Topics: Antifungal Agents; Aspergillus; Ciclopirox; Female; Foot Dermatoses; Humans; Middle Aged; Naphthalen

2009
Hydrosoluble medicated nail lacquers: in vitro drug permeation and corresponding antimycotic activity.
    The British journal of dermatology, 2010, Feb-01, Volume: 162, Issue:2

    Topics: Absorption; Administration, Topical; Animals; Antifungal Agents; Cattle; Ciclopirox; Hoof and Claw;

2010
Susceptibility testing of amorolfine, bifonazole and ciclopiroxolamine against Trichophyton rubrum in an in vitro model of dermatophyte nail infection.
    Medical mycology, 2009, Volume: 47, Issue:7

    Topics: Administration, Topical; Antifungal Agents; Ciclopirox; Humans; Imidazoles; Microbial Sensitivity Te

2009
Ciclopirox nail lacquer for the treatment of onychomycosis: an open non-comparative study.
    The Journal of dermatology, 2010, Volume: 37, Issue:2

    Topics: Administration, Topical; Adult; Antifungal Agents; Ciclopirox; Female; Foot Dermatoses; Humans; Lacq

2010
Effect of a novel penetration enhancer on the ungual permeation of two antifungal agents.
    The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:6

    Topics: Adenosine Triphosphate; Administration, Topical; Antifungal Agents; Cadaver; Ciclopirox; Humans; In

2010
Validation of bovine hoof slices as a model for infected human toenails: in vitro ciclopirox transungual permeation.
    The British journal of dermatology, 2011, Volume: 165, Issue:1

    Topics: Administration, Topical; Animals; Antifungal Agents; Cattle; Ciclopirox; Disease Models, Animal; Hoo

2011
Establishment of a novel model of onychomycosis in rabbits for evaluation of antifungal agents.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:7

    Topics: Animals; Antifungal Agents; Ciclopirox; Lacquer; Male; Models, Biological; Morpholines; Onychomycosi

2011
Case report: onychomycosis due to Trichophyton schoenleinii.
    Mycoses, 2012, Volume: 55, Issue:2

    Topics: Antifungal Agents; Ciclopirox; Foot Dermatoses; Humans; Male; Middle Aged; Mycological Typing Techni

2012
[When the nail is the polished one].
    MMW Fortschritte der Medizin, 2012, May-31, Volume: 154, Issue:10

    Topics: Administration, Topical; Antifungal Agents; Ciclopirox; Combined Modality Therapy; Disease Progressi

2012
Onychomycosis due to Neoscytalidium treated with oral terbinafine, ciclopirox nail lacquer and nail abrasion: a pilot study of 25 patients.
    Mycopathologia, 2013, Volume: 175, Issue:1-2

    Topics: Administration, Oral; Administration, Topical; Ascomycota; Ciclopirox; Debridement; Female; Humans;

2013
Onychomycosis: current treatment options.
    Journal of the American Academy of Nurse Practitioners, 2003, Volume: 15, Issue:4

    Topics: Antifungal Agents; Ciclopirox; Female; Humans; Itraconazole; Male; Middle Aged; Onychomycosis; Patie

2003
I've heard there's a nail polish for nail fungus. Does it work?
    Mayo Clinic women's healthsource, 2003, Volume: 7, Issue:10

    Topics: Administration, Topical; Antifungal Agents; Ciclopirox; Humans; Onychomycosis; Pyridones

2003
Action mechanisms of modern antifungal agents and resulting problems in the management of onychomycosis.
    Mycoses, 2003, Volume: 46, Issue:11-12

    Topics: Antifungal Agents; Ciclopirox; Combined Modality Therapy; Humans; Microbial Sensitivity Tests; Micro

2003
Fungus-free versus disease-free nails.
    Journal of the American Academy of Dermatology, 2004, Volume: 50, Issue:1

    Topics: Antifungal Agents; Ciclopirox; Humans; Onychomycosis; Pyridones; Remission Induction

2004
Managing simple chronic paronychia and onycholysis with ciclopirox 0.77% and an irritant-avoidance regimen.
    Cutis, 2004, Volume: 73, Issue:1

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Chronic Dise

2004
[Onychomycosis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2004, Volume: 55, Issue:2

    Topics: Antifungal Agents; Ciclopirox; Debridement; Diagnosis, Differential; Drug Therapy, Combination; Fluc

2004
Treatment costs of three nail lacquers used in onychomycosis.
    The Journal of dermatological treatment, 2005, Volume: 16, Issue:5-6

    Topics: Adult; Antifungal Agents; Ciclopirox; Drug Costs; Europe; Female; Foot Dermatoses; Hand Dermatoses;

2005
Congenital candidal onychomycoses: effective cure with ciclopirox olamine 8% nail lacquer.
    The British journal of dermatology, 2006, Volume: 154, Issue:3

    Topics: Administration, Topical; Antifungal Agents; Candidiasis; Ciclopirox; Hand Dermatoses; Humans; Infant

2006
Dystrophic onychomycosis due to Microsporum gypseum.
    Mycoses, 2006, Volume: 49, Issue:4

    Topics: Adult; Ciclopirox; Female; Humans; Microsporum; Naphthalenes; Onychomycosis; Pyridones; Terbinafine

2006
[Bilateral proximal cellulitis and onychomycosis in both big toes due to Fusarium solani].
    Revista iberoamericana de micologia, 2006, Volume: 23, Issue:4

    Topics: Antifungal Agents; Cellulitis; Ciclopirox; Diabetes Mellitus, Type 2; Disease Susceptibility; Drug R

2006
Identification and in vitro antifungal susceptibility testing of 200 clinical isolates of Candida spp. responsible for fingernail infections.
    Mycopathologia, 2007, Volume: 164, Issue:1

    Topics: Antifungal Agents; Brazil; Candida; Candidiasis; Ciclopirox; Fluconazole; Hand Dermatoses; Humans; I

2007
In Vitro penetration of a novel oxaborole antifungal (AN2690) into the human nail plate.
    Journal of pharmaceutical sciences, 2007, Volume: 96, Issue:10

    Topics: Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chemistry, Pharmaceutic

2007
[Cutaneous and nail infections caused by Hendersonula toruloidea].
    Annales de dermatologie et de venereologie, 1993, Volume: 120, Issue:3

    Topics: Adult; Antifungal Agents; Ciclopirox; Dermatomycoses; Diagnosis, Differential; Female; Hand Dermatos

1993
[Onychomycoses--therapeutic challenge for physician and patient. Report from the MYK 92 26th Scientific Meeting of the German-speaking Mycology Association. Graz, 4 September 1992].
    Fortschritte der Medizin. Supplement : die Kongressinformation fur die Praxis, 1993, Volume: 139

    Topics: Antifungal Agents; Ciclopirox; Humans; Onychomycosis; Pyridones

1993
[Topical therapy of onychomycoses with 8% ciclopirox laquer. An open, non-comparative study].
    Fortschritte der Medizin, 1993, Apr-30, Volume: 111, Issue:12

    Topics: Administration, Topical; Adult; Aged; Antifungal Agents; Ciclopirox; Female; Humans; Male; Middle Ag

1993
Economic evaluation of antifungal agents in the treatment of toenail onychomycosis in Germany.
    Dermatology (Basel, Switzerland), 1996, Volume: 193, Issue:3

    Topics: Algorithms; Antifungal Agents; Ciclopirox; Cost-Benefit Analysis; Costs and Cost Analysis; Decision

1996
[Hydroxy pyridone as antimycotic agent].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1996, Volume: 47, Issue:11 Suppl

    Topics: Adult; Age Factors; Antifungal Agents; Ciclopirox; Humans; Infant; Infant, Newborn; Onychomycosis; P

1996
Ciclopirox (Penlac) nail lacquer for onychomycosis.
    The Medical letter on drugs and therapeutics, 2000, Jun-12, Volume: 42, Issue:1080

    Topics: Antifungal Agents; Ciclopirox; Clinical Trials as Topic; Dose-Response Relationship, Drug; Erythema;

2000
Ciclopirox nail lacquer topical solution 8%.
    Skin therapy letter, 2000, Volume: 6, Issue:1

    Topics: Administration, Topical; Antifungal Agents; Ciclopirox; Clinical Trials as Topic; Humans; Onychomyco

2000
Use of caryophyllene oxide as an antifungal agent in an in vitro experimental model of onychomycosis.
    Mycopathologia, 1999, Volume: 148, Issue:2

    Topics: Animals; Antifungal Agents; Ciclopirox; Hoof and Claw; Humans; Imidazoles; Onychomycosis; Polycyclic

1999
Successful treatment of onychomycosis with ciclopirox nail lacquer: a case report.
    Cutis, 2001, Volume: 68, Issue:2 Suppl

    Topics: Administration, Topical; Aged; Antifungal Agents; Ciclopirox; Foot Dermatoses; Humans; Male; Onychom

2001
[New treatments of onychomycoses].
    Annales de dermatologie et de venereologie, 1992, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifungal Agents; Candidiasis; Ciclopirox; Fluconazole; Foot Dermatoses; H

1992
Ciclopirox nail lacquer 8%: in vivo penetration into and through nails and in vitro effect on pig skin.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1991, Volume: 4, Issue:2

    Topics: Administration, Topical; Animals; Antifungal Agents; Biological Transport; Candida; Ciclopirox; Cosm

1991
A clinical and laboratory study of ciclopirox olamine (8% Batrafen) in the treatment of onychomycosis.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 1991, Volume: 6, Issue:3

    Topics: Adult; Aged; Antifungal Agents; Candida albicans; Ciclopirox; Female; Foot Dermatoses; Hand Dermatos

1991
Onychomycosis and AIDS: treatment with topical ciclopirox olamine.
    International journal of dermatology, 1990, Volume: 29, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Administration, Topical; Antifungal Agents; Ciclopirox; Hand Der

1990
Hendersonula toruloidea infection: successful response of onychomycosis to nail avulsion and topical ciclopiroxolamine.
    Acta dermato-venereologica, 1987, Volume: 67, Issue:6

    Topics: Administration, Cutaneous; Adult; Antifungal Agents; Ciclopirox; Hand Dermatoses; Humans; Male; Mito

1987